Comparative Study on the Clinical Efficacy and Safety of Acitretin and MTX in the Treatment of Pustular Psoriasis by TLR7/MyD88/CXCL16 Pathway by Jiajing Lu, Yu Wang, Ying Li, Yu Gong, Yangfeng Ding, Yuling Shi

“…MTX was used in the control group, and different doses of acitretin were used in the study group, which were divided into low-dose group (n=13), medium-dose group (n=13), and high-dose group (n=14). Symptom relief time, recurrence rate, GPPASI improvement rate, treatment response rate, BSA, DLQI score, and TLR7 and CXCL16 levels were compared among four groups. …”
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Moxibustion for Herpes Zoster and Postherpetic Neuralgia: A Meta-Analysis by Yuanen Huang, Jingping Wu, Hongbin Cheng, Yanling Liu

“…The VAS scales, WMD = 1.69 (95% CI: 1.17∼2.22), and the time of analgesia, WMD = 2.41 (95% CI: 3.26∼1.73), indicated that moxibustion surpassed others in the relief of pain. NRS was just reported in one study. …”
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Innovative Diagnostic Approaches and Treatment Strategies for Endometriosis: Current Trends and Future Direction - Review by Wiktoria Domino, Joanna Śnieżna, Wojciech Florczak, Karol Dzwonnik, Urszula Zelik, Jagienka Włodyka, Gabriela Trestka, Maria Przygoda, Jakub Dziewic, Kamila Stępień, Sabina Adamczyk

“…The primary goals of treatment include pain relief, improving the patient's quality of life, preventing disease recurrence, preserving fertility, and reducing the need for surgery. …”
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Impact of functional re-education and environmental adaptation in cancer patients with respiratory pathology: Study protocol. by Eduardo Jose Fernandez-Rodriguez, Maria Isabel Rihuete-Galve, Alberto Garcia-Martin, Celia Sanchez-Gomez, Fausto Jose Barbero-Iglesias, Roberto Mendez-Sanchez, Ana Silvia Puente-Gonzalez, Susana Saez-Gutierrez, Emilio Fonseca-Sanchez, Juan Jesus Cruz-Hernandez

“…While traditional clinical approaches, primarily focused on pharmacological interventions, are commonly employed to manage dyspnoea, we argue that these methods may not always provide optimal symptomatic relief. Therefore, we propose a study protocol to implement an interdisciplinary intervention for these patients. …”
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Improved Analgesic Effect of Paravertebral Blocks before and after Video-Assisted Thoracic Surgery: A Prospective, Double-Blinded, Randomized Controlled Trial by Lihua Chu, Xiaolin Zhang, Yaping Lu, Guohao Xie, Shengwen Song, Xiangming Fang, Baoli Cheng

“…Paravertebral block (PVB) was proven to provide effective analgesia in patients with VATS; however, there is no difference in pain relief between preoperative PVB and postoperative PVB. …”
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SCN10A gene polymorphism is associated with pain sensitivity and postoperative analgesic effects in patients undergoing gynecological laparoscopy by Yang Gao, Jing Li, Lin Gan, Meng Cai, Xiaofeng Lei, Jin Yu

“…The AA group exhibited more self-control analgesic pump compressions within the first 24 h post-surgery, quicker depletion of analgesics in the pump, and lower patient satisfaction with pain relief compared to GA and GG groups (P < 0.05). Conclusions Female patients with homozygous SCN10A mutations may experience higher preoperative pain scores and increased sensitivity to postoperative pain following gynecological laparoscopic surgery with intravenous patient-controlled analgesia. …”
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Community disaster exposure and first onset of depression: A panel analysis of nationally representative South African data, 2008-2017. by Andrew Tomita, Busisiwe P Ncama, Yoshan Moodley, Rashieda Davids, Jonathan K Burns, Tafadzwanashe Mabhaudhi, Albert T Modi, Rob Slotow

“…Given that many individuals in South Africa rely on social, food parcel relief, and health services from government/public sector, timely access to community-based supportive intervention is needed for disaster survivors, prioritizing socially vulnerable groups to help mitigate problems associated with mental health challenges.…”
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Comparative Evaluation of Functional Outcomes in High Condylar Fractures Treated with Closed Methods with and without Temporomandibular Joint Arthrocentesis: A Research Protocol fo... by Sachindra Dubey, Nitin Bhola, Anchal Agarwal

“…Hence, the present study will present the utility of arthrocentesis as an adjunct procedure to closed reduction in high condylar fractures, improving the functionality of the condyle, providing pain relief, increasing mouth opening and bite force, stabilising bilateral occlusion, and normalising excursive movements. …”
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Efficacy of ultrasound guided erector spinae plane block compared to wound infiltration for postoperative analgesia following laparoscopic living donor nephrectomy: a double-blinde... by Sekar Loganathan, Kamal Kajal, Kashish Garg, Sameer Sethi, Deepesh B Kenwar, Amit Sharma, Ashish Aditya, Varun Mahajan, Naveen B Naik, Rajnikant Kumar

“…Conclusion Ultrasound-guided ESPB provided effective pain relief compared to wound infiltration with local anaesthetic in patients who underwent LLDN. …”
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Efficacy and safety of Lutai Danshen Baishao granules for treating female melasma: A randomized, double-blind, placebo-controlled trial by Meiyu Lyu, Yi Yang, Jinlian Liu, Wenting Fei, Min Fu, Yunting Hong, Hongguo Rong, Chun Wang, Linyuan Wang, Jianjun Zhang

“…The total TCM symptom evaluation score significantly decreased (test group: 6.00 vs. placebo group: 7.00, P = .001), with significant relief in symptoms such as improvement in dark lips, nails, and waist soreness in the test group, compared with that in the placebo group (P < .05). …”
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The Effectiveness of Cancer Pain Management in a Tertiary Hospital Outpatient Pain Clinic in Thailand: A Prospective Observational Study by Suratsawadee Wangnamthip, Skaorat Panchoowong, Carolina Donado, Kimberly Lobo, Pimporn Phankhongsap, Pinyo Sriveerachai, Pramote Euasobhon, Pranee Rushatamukayanunt, Sahatsa Mandee, Nantthasorn Zinboonyahgoon, Charles B. Berde

“…The current Siriraj multidisciplinary approach provided effective relief of pain and stabilization of other cancer-related symptoms. …”
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Enhancing Pan evaporation predictions: Accuracy and uncertainty in hybrid machine learning models by Khabat Khosravi, Aitazaz A. Farooque, Amir Naghibi, Salim Heddam, Ahmad Sharafati, Javad Hatamiafkoueieh, Soroush Abolfathi

“…Eight input scenarios were developed using both manual and automated feature selection techniques, including correlation-based subset selection evaluation (CfsSubsetEval or CSE), Principal Component Analysis (PCA), and the Relief Attribute Evaluator (RAE). The results demonstrate that the BA-Kstar ensemble model achieved superior performance (R2 = 0.91, RMSE = 1.60, NSE = 0.91, and RSR = 0.30). …”
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Repetitive Transcranial Magnetic Stimulation for the Treatment of Complex Regional Pain Syndrome: A Pilot Study by Foglia SD, Drapeau CC, Ramdeo KR, Adams FC, Soppitt DB, Rehsi RS, Shanthanna H, Nelson AJ

“…Repetitive transcranial magnetic stimulation (rTMS) has shown to be beneficial for pain relief in neuropathic pain and initial evidence in CRPS is promising, but studies are limited. …”
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Intratonsillar Immunotherapy: A Convenient and Effective Alternative to Subcutaneous Immunotherapy for Allergic Rhinitis by Tian Gu, Wei Zhang, Lu Tan, Rong Xiang, Peiqiang Liu, Jingyu Huang, Qin Deng, Yuqin Deng, Zezhang Tao, Shiming Chen, Yu Xu

“…ITIT demonstrated superior and faster symptom relief, especially in younger patients, while requiring markedly fewer doses and injections than SCIT. …”
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“If that would have lessened my symptoms, that would have been great...”: a qualitative study about the acceptability of tecovirimat as treatment for mpox by Sara Paparini, Rosalie Hayes, Benjamin Weil, Will Nutland, Ismael Maatouk, Teodora Wi, Chloe M. Orkin, Rosamund Lewis

“…To increase acceptability of such treatments, clinicians should ensure patients are aware of mpox symptom management options, including pain relief; acknowledge and address patient concerns upfront and within the context of non-stigmatising care; and communicate offers in a consistent and supportive manner in line with locally approved eligibility criteria and protocols at the time.…”
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Spacer-type tibial osteotomy versus open wedge high tibial osteotomy and unicompartmental knee arthroplasty for Kellgren-Lawrence grade 3–4 medial unicompartmental knee osteoarthri... by Yi Zhang, Xiangzhi Yin, Jinli Chen, Yingze Zhang, Tengbo Yu

“…UKA achieved the most significant pain relief based on VAS (P = 0.014), KSS pain score (0.030), and WOMAC score (P = 0.000) at 6 months postoperatively, but there were no differences between three groups at 12 and 24 months postoperatively. …”
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Outcomes of Open Reduction and Modified McLaughlin’s Procedure in Neglected Posterior Shoulder Dislocation by Vikas, Jatin Prakash, Karan Maggo, Jujhar Singh, Ankesh Jain, Naval Bhatia

“…The procedure leads to significant improvements in Constant Shoulder Scores, pain relief, functional recovery, and shoulder stability. …”
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Study on mechanical properties of sandstone damaged by blasting load under triaxial cyclic loading and unloading by Haibo Wang, Genshuo Zhu, Ziyi Lu, Qi Zong, Hao Wang

“…Therefore, the safety and stability of the surrounding rock should be strictly monitored when applying blasting pressure relief technology to avoid safety accidents.…”
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Study of Ultrasound-Assisted Low-Pressure Closed Acid Digestion Method for Trace Element Determination in Rock Samples by Inductively Coupled Plasma Mass Spectrometry by Xijuan Tan, Yunxiu Ren, Ting Liang, Denghong Wang

“…By using 1.5 mL of a binary acid mixture of HNO₃–HF with a ratio of 2:1, rock powder samples of 50 mg were completely decomposed in 12 h at 140 °C after 4 h of ultrasonic treatment with or without pressure relief procedure. The element extraction efficiency of this method was evaluated via the yielded relative errors (REs) of the trace elements in a series of geological standard reference materials (SRMs) with compositions from basic to acidic. …”
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Experimental studies of unsteady processes of cryogenic liquid evaporation in rocket tank model by V. I. Trushlyakov, V. A. Urbansky, A. N. Pavlenko, V. E. Zhukov, E. Yu. Sukhorukova

“…., given external thermal loading, pressure relief after reaching 4 atm. up to 1 atm. The technique of processing the results of pressure and temperature measurements with the assumptions and limitations is given.…”
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