Efficacy of drugs most commonly prescribed at functional gastrointestinal diseases (functional dyspepsia syndrome and irritable bowel syndrome) observational study results by V. T. Ivashkin, Ye. A. Poluektova, D. V. Reykhart, O. S. Shifrin, A. G. Beniashvili, O. S. Lyashenko, A. V. Belostotsky

“…Modes of treatment which included trimebutine demonstrated higher efficacy in comparison to treatment algorithms, which included antispasmodic medications with respect to relief of all symptoms (according to the «7×7» questionnaire data), except for constipation and in disorders of stool consistency (firm stool): efficacy of trimebutinecontaining moods for those symptoms was comparable to those with application of spasmolytic drugs. …”
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Postendodontic Pain after Pulpotomy or Root Canal Treatment in Mature Teeth with Carious Pulp Exposure: A Multicenter Randomized Controlled Trial by Mohammad Jafar Eghbal, Ali Haeri, Arash Shahravan, Ali Kazemi, Fariborz Moazami, Mohammad Ali Mozayeni, Eshaghali Saberi, Mohammad Samiei, Mehdi Vatanpour, Alireza Akbarzade Baghban, Mahta Fazlyab, Ardavan Parhizkar, Mahboobe Ahmadi, Nazila Akbarian Rad, Shima Bijari, Delaram Bineshmarvasti, Paria Davoudi, Roya Dehghan, Mandana Dehghani, Habibollah Ebrahimi, Nafiseh Emami, Nafiseh Farajian, Rahim Fereidooni, Gelareh Ghobadi, Mostafa Ghodrati, Atefeh Gohari, Azadeh Hashemi, Mohammadreza Hosseini, Elham Karami, Nasir Kheirabadi, Sepideh Kozegari, Hadi Labaf Ghasemi, Alireza Majidi, Parastu Malekzadeh, Vahid Mehrabi, Mehrnush Mohammadi, Leila Moradi Eslami, Atefeh Noghani, Negin Omatali, Negar Pourhatami, Behnam Rahbani Nobar, Saeid Rahmani, Parviz Shafaq, Sara Soofiabadi, Somaye Teimoori, Farzaneh Vatandoost, Saeed Asgary

“…Pulpotomy with MTA/CEM and RCT demonstrate comparable and effective postoperative pain relief.…”
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Magnesium in pain control - mechanisms of action in perioperative pain, neuropathic pain and migraine by Anna Konarska, Artur Fabijański, Adriana Dukacz, Wojciech Firlej, Joanna Rychlewska-Duda, Justyna Lisiecka, Michał Nowak, Mateusz Janik, Barbara Ufnalska, Anna Machowiak

“…Its use can reduce opioid consumption, enhance pain relief, and improve outcomes, highlighting the need for further research into its clinical applications in pain management.   …”
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Phytoplankton growth and succession driven by topography and hydrodynamics in seasonal ice-covered lakes by Ziyue Zhao, Yanfeng Wu, Y. Jun Xu, Yexiang Yu, Guangxin Zhang, Dehua Mao, Xuemei Liu, Changlei Dai

“…The effects of topographic factors (relief, surface curvature, water depth, slope gradient, roughness, and slope aspect) on the hydrodynamic field and phytoplankton distribution were discussed. …”
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Exploration of the quantitative-effectiveness association between acupuncture temporal parameters and chemotherapy-induced peripheral neuropathy in cancer patients: a dose-response... by Hao Tian, Qin Luo, Liuyang Huang, Liuyang Huang, Liuyang Huang, Guang Chen, Mingsheng Sun, Fanrong Liang

“…The identified time-dose-response relationship suggests that tailoring acupuncture frequency and duration can to optimize pain relief in CIPN patients. Future high-quality studies and large-scale multicenter clinical trials are needed to validate these findings.…”
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Characterization of Sleep Structure and Autonomic Dysfunction in REM Sleep Behavior Disorder by Nicla Mandas, Maximiliano Mollura, Giulia Baldazzi, Parisa Sattar, Maria Mura, Elisa Casaglia, Michela Figorilli, Laura Giorgetti, Pietro Mattioli, Francesco Calizzano, Francesco Fama, Dario Arnaldi, Monica Puligheddu, Danilo Pani, Riccardo Barbieri

“…Coexistence of PD seems to improve sleep quality, possibly due to a sleep-related relief of their symptoms.…”
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Efficacy of Functional Endoscopic Sinus Surgery and Impact of Chronic Lung Disease on its Outcome in Patients of Chronic Rhinosinusitis by Minakshmi Karmakar, V D Prasanna Kumar Vasamsetty, Bonapart Chowdhury

“…In view of the above, this study was carried out to determine the prevalence and severity of various symptom manifestations of chronic rhinosinusitis as well as to compare the symptomatic relief of the patients following surgery by regular follow ups and by using grading systems. …”
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Hydrogel loaded with cerium-manganese nanoparticles and nerve growth factor enhances spinal cord injury repair by modulating immune microenvironment and promoting neuronal regenera... by Zhaoyang Gong, Zhenhao Chen, Dachuan Li, Xiao Lu, Jianwei Wu, Hanqiu Sun, Ximeng Wang, Siyang Liu, Xinlei Xia, Feizhou Lu, Jianyuan Jiang, Chi Sun, Hongli Wang, Feng Zeng, Xiaosheng Ma

“…Abstract Background Spinal cord injury (SCI) treatment remains a formidable challenge, as current therapeutic approaches provide only marginal relief and fail to reverse the underlying tissue damage. …”
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Détermination du statut du Chimpanzé, Pan troglodytes verus, dans une zone non protégée de savane boisée à Bagnomba, Sénégal : Implication pour sa conservation by Papa Ibnou Ndiaye, Landing Badji, Stacy Marie Lindshield, Cheikh Tidiane Bâ, Jill Pruetz

“…Les particularités écologiques des habitats du chimpanzé dans cette zone (relief, végétation, disponibilité d’aliments, entre autres) associées à leur caractère sacré par les populations locales constituent des atouts qui favoriseraient la conservation des chimpanzés dans cette zone si des mesures idoines de protection étaient prises. …”
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Chemotherapy plus therapeutic plasmapheresis with 4% human albumin solution in multiple myeloma patients with acute kidney injury: a prospective, open-label, proof-of-concept study by Tianzhi Wu, Dandan Liu, Shangqin Liu, Hui Xiao, Bei Xiong, Yi Zhou, Yafen Xiong, Qin Cui, Jiang Wu, Minghui Liu, Hongli Liu, Yiming Li, Meixin Wang, Xueqin Bao, Ye Li, Fuling Zhou

“…The three symptoms with the greatest relief were urine foam, poor appetite, and blurred vision. …”
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Biotechnological Phytocomplex of <i>Zanthoxylum piperitum</i> (L.) DC. Enhances Collagen Biosynthesis In Vitro and Improves Skin Elasticity In Vivo by Giovanna Rigillo, Giovanna Pressi, Oriana Bertaiola, Chiara Guarnerio, Matilde Merlin, Roberto Zambonin, Stefano Pandolfo, Angela Golosio, Francesca Masin, Fabio Tascedda, Marco Biagi, Giulia Baini

“…Biologically, <i>Z. piperitum</i> has antimicrobial, antioxidant, and anti-inflammatory properties, and it is studied for its potential benefits in pain relief and digestive health. This study proposed a novel biotechnological <i>Z. piperitum</i> phytocomplex (ZPP) obtained by plant cell culture for skin health, specifically targeting collagen synthesis, extracellular matrix stability, and resilience against cellular stress. …”
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Chemical Characterization and Differential Lipid-Modulating Effects of Selected Plant Extracts from Côa Valley (Portugal) in a Cell Model for Liver Steatosis by Ricardo Amorim, Mário Pedro Marques, Catarina Melim, Carla Varela, Vilma A. Sardão, José Teixeira, Maria Inês Dias, Lillian Barros, Paulo J. Oliveira, Célia Cabral

“…., and <i>Geranium lucidum</i> L. (pain relief, gastric issues). Given their rich ethnomedicinal history, we evaluated their protective effects on an in vitro model of metabolic dysfunction-associated steatotic liver disease (MASLD). …”
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Double-Blind Clinical Trial of Arginine Supplementation in the Treatment of Adult Patients with Sickle Cell Anaemia by Renata M. N. Eleutério, Francisco O. Nascimento, Tamara G. Araújo, Marilena F. Castro, Tarcísio P. Almeida Filho, Pedro A. Maia Filho, José Eleutério, Darcielle B. D. Elias, Romélia P. G. Lemes

“…The use of L-arginine as a coadjuvant in the treatment of sickle cell anaemia may function as a potential tool for pain relief, consequently improving the life of patients.…”
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Association of epidural labor analgesia with maternal and neonatal outcomes in women with preeclampsia: a propensity score-matched single-center retrospective cohort study by Xi-Zhu Wu, Tuan-Fang Fang, Yi-Han Zheng, Su-Jing Zhang, Yi Xie, Xiang Gao, Guo-Lin Lu

“…Abstract Background Epidural labor analgesia (ELA) is widely and safely used for labor pain relief. However, it remains unclear whether ELA affects maternal and neonatal outcomes in women suffering from preeclampsia. …”
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Seabed Acoustic Mapping Revealing an Uncharted Habitat of Circular Depressions Along the Southeast Brazilian Outer Shelf by Ana Carolina Lavagnino, Marcos Daniel Leite, Tarcila Franco, Pedro Smith Menandro, Fernanda Vedoato Vieira, Geandré Carlos Boni, Alex Cardoso Bastos

“…A total of 3660 depressions were mapped between 46 and 85 m in depth, reaching an area of 460 m² and 5 m relief. The continental shelf morphology was subdivided into three sectors based on morphology: inter-valleys, valley edges, and valley flanks, and eleven sites were selected for direct sampling/imaging at the CDs along the sectors. …”
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Inferior vena cava ultrasound in acute decompensated heart failure: design rationale of the CAVA‐ADHF‐DZHK10 trial by Alexander Jobs, Reinhard Vonthein, Inke R. König, Jane Schäfer, Matthias Nauck, Svenja Haag, Carlo Federico Fichera, Thomas Stiermaier, Jakob Ledwoch, Alisa Schneider, Miroslava Valentova, Stephan vonHaehling, Stefan Störk, Dirk Westermann, Tobias Lenz, Natalie Arnold, Frank Edelmann, Philipp Seppelt, Stephan Felix, Matthias Lutz, Felix Hedwig, Martin Borggrefe, Clemens Scherer, Steffen Desch, Holger Thiele

“…However, ultrasound results will only be reported to treating physicians in the intervention group. Treatment target is relief of congestion‐related signs and symptoms in both groups with the additional goal to reduce the IVC diameter ≤21 mm and increase IVC collapsibility >50% in the intervention group. …”
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Characterizing populations prioritized for PrEP in 19 African countries: a review of national guidance by Lauren A. Graybill, Caroline N. McKay, Jiayu Wang, Nadia A. Sam‐Agudu, Marcel Yotebieng, Friday Saidi, Linda‐Gail Bekker, Bonnie E. Shook‐Sa, Benjamin H. Chi, Nora E. Rosenberg

“…Methods Between January and June 2023, we searched for current National HIV Treatment and Prevention Guidelines, National HIV Strategic Plans, and the United States President's Emergency Plan for AIDS Relief (PEPFAR) Country Operational Plans (COPs) for all African countries implementing PrEP programmes supported by PEPFAR in 2022. …”
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The impact of nationality status and place of residency on health-related social needs and quality of life among Palestinian Refugees in Jordan by Hamza Alduraidi, Rahaf Issam Abu Zayid, Noor Mahmoud Jaber, Bassam Saleh Hijazi, Sa'ed Radwan Khamis, Hasan Fahed Awad, Marah Al-Khateeb, Saif alnour Mahmoud Aldhirat, Ahmad Amjed Toubasi

“…International states and organizations should help meet these needs by funding the United Nations’ Relief and Work Agency for Palestinian Refugees in the Near East (UNRWA) and the Jordanian government. …”
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Evaluation of Common and Atypical Clinical Presentations of Tinea Faciei: A Cross-sectional Study from Barabanki, Uttar Pradesh, India by Suganita, Deepika Agarwal, Sonal Sachan, Vandana Yadav, Harshit Jaiswal, Divya Prajapati

“…Moreover, the present study highlights that many patients use steroids in the form of topical, oral and injection to get quick relief, which can complicate the diagnosis.…”
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Corticostriatal glutamate‐mediated dynamic therapeutic efficacy of electroacupuncture in a parkinsonian rat model by Xinxin Jiang, Min Sun, Yitong Yan, Yanhua Wang, Xinyu Fan, Jing Wei, Ke Wang, Peirong Liang, Zirui Wang, Jihan Wang, Xiaomin Wang, Jun Jia

“…EA effectively suppresses excessiveglutamate transmission and high‐beta synchronization, contributing to motorsymptom relief. Activation of corticostriatalglutamatergic projections may hinder the efficacy of EA.…”
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