Association Between Patient-Reported Pain and Remission or Low Disease Activity in Patients with Rheumatoid Arthritis: Data from RA-BE-REAL Prospective Observational Study by Peter C. Taylor, Walid Fakhouri, Samuel Ogwu, Ewa Haladyj, Inmaculada de la Torre, Bruno Fautrel, Rieke Alten, Peter Nash, Eugen Feist

“…Almost half the patients who were in remission/LDA receiving baricitinib achieved ≥ 70% pain relief. At 3 M, the proportion of patients in remission/LDA with pain VAS ≤ 20 mm was 62.1% (cohort A), 55.0% (cohort B-TNFi) and 55.6% (cohort B-OMA), while for those not in remission/LDA, it was 8.5% and 8.7% (cohort A and B-TNFi, respectively) and 5.3% (B-OMA). …”
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Determination of Cenozoic Sedimentary Structures Using Integrated Geophysical Surveys: A Case Study in the Hebei Plain, China by Yi Yang, Jie Zhang, Junjie Wu, Pei Li, Xingchun Wang, Qingquan Zhi, Guojiang Hao, Jianhua Li, Xiaohong Deng

“…In this study, gravity, magnetotelluric (MT) sounding and shallow seismic methods are used to explore the basement relief and stratigraphic structure of the alluvial proluvial area in front of Taihang Mount in the North China Plain so as to understand the geological structure and sedimentary evolution of the area. …”
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Gastroprotective Effects of Aqueous Extracts of Broccoli Stems on Acute Injury in Rats: A Comprehensive Evaluation of Gastric Function and Inflammatory Responses by Jihye Choi, Yuseong Jang, Hyeon-Gi Paik, Melissa Hyun-Joo Ha, Jungkee Kwon

“…<i>Results</i>: The BSE 250 mg/kg group exhibited significant relief of clinical signs compared to the negative control group. …”
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Gaussian process latent variable models-ANN based method for automatic features selection and dimensionality reduction for control of EMG-driven systems by Maham Nayab, Asim Waris, Muhammad Jawad Khan, Dokhyl AlQahtani, Ahmed Imran, Syed Omer Gilani, Umer Hameed Shah

“…In individual comparisons, GPLVM had the shortest computational time (29 s), which was significantly less than that of all the other models (p &lt; 0.05), with PCA following at approximately 35 s and Relief at approximately 57 s, while PPCA took approximately 69 s, and Lasso exhibited higher computational costs than all the models but lower computational costs than did the original set. …”
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Efficacy and Safety of Different Acupuncture Treatments for Cancer-Related Pain: A Systematic Review and Network Meta-Analysis by Tianle Xie MD, Can Liu MD, Yudi Wu MD, Xiuxiu Li MD, Qianyun Yang PhD, Jing Tan PhD

“…Network meta-analysis showed that, compared to Usual Medicine, Acupuncture + Usual Medicine + Traditional Chinese medicine (MD = −1.83, 95% CI: −2.86 to −0.80) could reduce NRS scores, Acupuncture + Traditional Chinese medicine (OR = 30.86, 95% CI: 3.75-254.20) could improve cancer pain relief, Moxibustion + Usual Medicine (MD = 2.12, 95% CI: 0.43-3.80) could effectively improve KPS score, Acupuncture + Application of Chinese medicine (OR = 0.16, 95% CI: 0.04-0.66) is associated with a lower incidence of constipation, Electro-Acupuncture + Usual Medicine (OR = 0.11, 95% CI: 0.03-0.45) shows a lower incidence of nausea and vomiting, Acupuncture + Moxibustion + Usual Medicine (OR = 0.29, 95% CI: 0.09-0.90) is associated with a lower incidence of dizziness. …”
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Intravenous Oxycodone versus Intravenous Morphine in Cancer Pain: A Randomized, Open-Label, Parallel-Group, Active-Control Study by Kyung-Hee Lee, Jung-Hun Kang, Ho-Suk Oh, Moon-Ki Choi, Byoung-Yong Shim, Young-Jun Eum, Hye-Jeong Park, Jin-Hyong Kang

“…While this reduction was similar between groups (3.5 ± 2.2 versus 3.1 ± 1.8, P value = 0.562), oxycodone achieved faster pain relief (average pain: 3.0 ± 1.6 versus 3.9 ± 1.6, P value = 0.020) on Day 2 and significant NRS reductions for worst pain on Day 2 (P value = 0.045) and current pain on Day 2 (P value = 0.035) and Day 5 (P value = 0.020) compared to morphine. …”
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LA GEOPEDOLOGIA COMO BASE PARA ZONIFICAR LA APTITUD FORESTAL EN UNA CUENCA DEL NOROESTE DE LA PATAGONIA ARGENTINA by Maria Cristina Frugoni, Romina González Musso, Gabriel Falbo, Dolores Zapiola

“…According to this approach three landscapes were recognized: glacial modeled mountains, plateau and valley. The relief consists mainly of steep to very steep slopes, and valley bottoms with poorly drained soils. …”
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Continuously relapsing (for two years) course of diarrheal variant of IBS (<i>Clinical case</i>) by Ye. A. Poluektova, S. Yu. Kuchumova, A. A. Kurbatova, A. A. Sheptulin, O. S. Shifrin, V. T. Ivashkin

“…Prescribed treatment included dioctaedric smectite, probiotic and antipsychotic drug, which had led to complete relief of all symptoms.Conclusion. Careful taking past history and carrying out detailed laboratory and instrumental tool investigation allowed to establish clinical diagnosis in the patient, and pathogenicly proven treatment promoted achievement of disease remission.…”
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Lecture poétique des langues locales : cas de Nyanndra Mun (Proverbes) du Roi Salomon by Koffi Samuel N’ZI & Kouamé Gilles YAO

“…Elle a porté essentiellement sur la langue baoulé[1] et permis, à travers l’analyse de quelques extraits de Nyanndra Mun (transcription en Baoulé du livre des proverbes du Roi Salomon), de mettre en relief les riches dimensions linguistiques et littéraires de cette langue locale. …”
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Assessing The Impact of Tea Production on The Economic Development of Local Community: A Case Study of Kayonza Tea Factory in Kayonza Sub- County Kanungu District. by Tukwasibwe, Joab

“…The study findings show that the factors that have favoured tea production were land availability which is a major factor consisting 90% of the respondents, farm labour, relief, agro-input use and the growing promotion as a strategic agricultural enterprise, the contributions of tea production in Kayonza sub-county Kanungu District were a source of income which is the major contribution of tea production (97%), employment opportunities, foreign exchange earner for the county, contributing to food security, infrastructural development, and the challenges affecting tea production in Kayonza sub-county Kanungu District were pest and diseases which is the major challenge to tea production (90%) cost of production, lack of comprehensive policies, , poor road networks and infrastructures, poor agricultural technology, marketing and value¬addition constraints, climatic changes and seasonal effects and poor access to information. …”
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Metabolite profile and antioxidant activities of Trikatu, black pepper, Javanese long pepper, and red ginger essential oils by Dewa Ayu Ika Pramitha, Tati Herlina, Iman Permana Maksum, Ari Hardianto, Abd. Wahid Rizaldi Akili, Jalifah Latip

“…These insights support broader applications in aromatherapy, wellness, and healthcare, where TR essential oil can be used for antioxidant support, stress relief, and as a natural supplement. Future research may further optimize these essential oils for targeted therapeutic and preventive applications.…”
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Multicentre, randomised controlled trial to investigate the effects of parental touch on relieving acute procedural pain in neonates (Petal) by Eleri Adams, Daniel Crankshaw, Ria Evans Fry, Rebeccah Slater, Caroline Hartley, Maria M Cobo, Fiona Moultrie, Annalisa G V Hauck, Vaneesha Monk, Shellie Robinson, Marianne van der Vaart, Luke Baxter, Ravi Poorun, Aomesh Bhatt

“…The trial aim is to determine whether parental touch prior to a painful clinical procedure provides effective pain relief in neonates.Methods and analysis This is a multicentre randomised controlled trial. …”
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Allopregnanolone relieves paclitaxel induced mechanical hypersensitivity via inhibiting spinal cord PGE2-EP2 mediated microglia-neuron signaling by Kunlin Guo, Lei Gao, Ping Li, Shanwu Feng, Liping Zhao, Xian Wang

“…Here, we investigated if allopregnanolone attenuates extracellular signal-regulated kinase (ERK) and its downstream prostaglandin E2 (PGE2) expression in the dorsal spinal cord concomitant with neuropathic pain relief in paclitaxel (PTX)-induced neuropathic pain model rats. …”
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A New Device Improves Signs and Symptoms of TMD by Ruggero Cattaneo, Davide Pietropaoli, Barry C. Cooper, Dino Capparè, Eleonora Ortu, Annalisa Monaco

“…ELIBA can be considered as a new device, potentially useful for head-neck pain relief in patients suffering from chronic TMD. In addition, its use promotes a muscles relaxation inducing freeway space increase. …”
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Diagnostics of chronic small intestinal obstruction in patient with ectopic pancreas in the Meckel's diverticulum (case report) by Zinaida A. Lemeshko, O. S. Shifrin, A. V. Korolev, T. L. Lemina, I. A. Sokolina, A. Ye. Leonovich, K. A. Lesko, A. S. Tertychny, V. T. Ivashkin

“…Surgical intervention for intussusception and resection of diverticulum-containing portion of the small intestine resulted in improvement of the patient state, relief of pain attacks and signs of intestinal obstruction. …”
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Spatiotemporal variations of water levels and river-lake interaction in the Poyang Lake basin under the extreme drought by Hexiang Chen, Guangqiu Jin, Hongwu Tang, Jinran Wu, You-Gan Wang, Zhongtian Zhang, Yanqing Deng, Siyi Zhang

“…During the drought period, both natural precipitation-driven flow increase in upstream rivers and water released from the dam provided short-term relief, though insufficient to fully mitigate the drought conditions.…”
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Comparative efficacy of <i>Bifidobacterium bifidum, Bifidobacterium longum, Bifidobacterium infantis, Lactobacillus rhamnosus</i> composition and prucalopride in treatment of const... by V. T. Ivashkin, O. M. Drapkina, A. A. Sheptulin, O. S. Shifrin, Ye. A. Poluektova, S. Yu. Kuchumova

“…Probiotic of Florasan-D and enterokinetic Resolor at application in patients with IBS-C for 4 wks possess similar efficacy in main symptom reduction, relief of BOS, improvement of quality of life. Florasan-D is better tolerated by patients due to gradual increase of stool frequency during treatment course.…”
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Analgesic efficacy and safety of methylene blue combined with cocktail for periarticular infiltration following total knee arthroplasty: a prospective, randomized, controlled study by Yijiang Deng, Yong Yang, Feng Zhu, Wenzhi Liu, Jiarui Chen, Guangmin Xu

“…Moreover, it synergistically enhanced the local anesthetic analgesia and provided sustained pain relief for at least 4 weeks.…”
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Increased TSPO alleviates neuropathic pain by preventing pyroptosis via the AMPK-PGC-1α pathway by Baolong Li, Kaiming Yu, Xiongyao Zhou, Jialu Sun, Le Qi, Weiye Li, Tuo Yang, Weizhen Li, Ningning Wang, Xiaosong Gu, Shusen Cui, Rangjuan Cao

“…Furthermore, Mendelian randomization analysis of GWAS data indicated that increased TSPO expression was linked to pain relief. Through drug screening, molecular docking, and behavioral assays, we identified zopiclone as a promising TSPO-targeting drug for pain treatment. …”
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Efficacy and Safety of a Stimulator Using Low-Intensity Pulsed Ultrasound Combined with Transcutaneous Electrical Nerve Stimulation in Patients with Painful Knee Osteoarthritis by Eu-Deum Kim, Yu Hui Won, Sung-Hee Park, Jeon-Hwan Seo, Da-Sol Kim, Myoung-Hwan Ko, Gi-Wook Kim

“…The effects of a stimulator using LIPUS with TENS on pain relief and functional improvement were not superior to the only TENS therapy. …”
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