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Promoter engineering with programmable upstream activating sequences in Aspergillus Niger cell factory
Published 2025-01-01“…A wide dynamic range of promoters, particularly strong promoters, are required for fine-tuning the regulation of gene expression to balance metabolic flux and achieve the high yields of desired products. …”
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42
Butyrate Supplementation Improves Intestinal Health and Growth Performance in Livestock: A Review
Published 2025-01-01“…Additionally, butyrate plays a role in the epigenetic regulation of gene expression through histone acetylation, influencing tissue development and immune modulation. …”
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43
Robust genome editing activity and the applications of enhanced miniature CRISPR-Cas12f1
Published 2025-01-01“…Furthermore, we demonstrate that eCas12f1 efficiently induces apoptosis in cancer cells and is compatible with base editing and regulation of gene expression, verifying its high utility and applicability in gene therapy research.…”
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44
Role of sirtuins in epigenetic regulation and aging control
Published 2024-04-01“…However, the SIRT influence on the epigenetic regulation of gene expression during the aging process and the development of disorders is one of the most important aspects of maintaining the homeostasis of organs and tissues. …”
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45
Introduction to genetic analysis /
Published 2020Table of Contents: “…Gene Isolation and Manipulation -- 11. Regulation of Gene Expression in Bacteria and Their Viruses -- 12. …”
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46
Effects of polyamines and indole on the expression of ribosome hibernation factors in <i>Escherichia coli</i> at the translational level
Published 2024-03-01“…Polyamines and indole are small regulatory molecules that are involved in the adaptation to stress in bacteria, including the regulation of gene expression. Genes, the translation of which is under the regulatory effects of polyamines, form the polyamine modulon. …”
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47
Different functions of PHF10 isoforms – subunits of the PBAF chromatin remodeling complex
Published 2019-03-01“…Chromatin remodelling multiprotein complexes play an important role in regulation of gene expression in embryogenesis and in the adult organism. …”
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48
MicroRNA-223 Expression Is Upregulated in Insulin Resistant Human Adipose Tissue
Published 2015-01-01“…MicroRNAs (miRNAs) are short noncoding RNAs involved in posttranscriptional regulation of gene expression and influence many cellular functions including glucose and lipid metabolism. …”
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49
Research Progress on Natural Products That Regulate miRNAs in the Treatment of Osteosarcoma
Published 2025-01-01“…miRNAs are small non-coding RNA molecules that play critical roles in the regulation of gene expression and have been closely associated with various diseases, including cancer. …”
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50
Identification of new genes regulating nodule development in Medicago truncatula: an in-silico approach
Published 2024-09-01“…This shows that IPD3 through interaction with these proteins could be involved in regulation of gene expression and cell cycle. Besides, we found a possible cytokinin transport gene ABCG38 and showed the activation of its expression in nodules compared to root. …”
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51
Argonaute2 modulates megakaryocyte development and sex-specific control of platelet protein expression and reactivity
Published 2025-01-01“…Platelet reactivity controlled by Ago2 reflects sex-specific regulation of gene expression potentially at both transcriptional and translational levels in megakaryocytes and platelets.…”
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52
A nociceptor-specific RNAi screen in Drosophila larvae identifies RNA-binding proteins that regulate thermal nociception
Published 2025-01-01“…Diverse RNA-binding proteins regulate the development and morphology of larval nociceptors, implying important roles for post-transcriptional regulation of gene expression in these neurons, but the importance of these mechanisms for nociceptive behavior has not been investigated systematically. …”
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53
Endometrial Cancer and Hypermethylation: Regulation of DNA and MicroRNA by Epigenetics
Published 2012-01-01“…Silencing of genes such as APC and CHFR, Sprouty 2, RASSF1A, GPR54, CDH1, and RSK4 by DNA hypermethylation, onset of Lynch syndrome due to hereditary epimutation of hMLH1 and hMSH2 mismatch repair genes, and regulation of gene expression by microRNAs may also underlie the carcinogenic mechanisms of endometrial cancer. …”
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54
Mono-allelic epigenetic regulation of polycistronic transcription initiation by RNA polymerase II in Trypanosoma brucei
Published 2025-02-01“…These findings suggest epigenetic chromatin-based regulation of gene expression is deeply conserved among eukaryotes, including early divergent eukaryotes that rely on polycistronic transcription.IMPORTANCEThe single-cell parasite Trypanosoma brucei causes lethal diseases in both humans and livestock. …”
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55
Identifying a Serum Exosomal-Associated lncRNA/circRNA-miRNA-mRNA Network in Coronary Heart Disease
Published 2021-01-01“…Functional enrichment analysis showed that DEMs were significantly enriched in “chromatin silencing at rDNA,” “telomere organization,” and “negative regulation of gene expression, epigenetic.” PPI network analysis showed that 25 hub DEMs were closely related to CHD, of which ubiquitin C (UBC) was the most important. …”
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56
Mycochemistry, antioxidant, anticancer activity, and molecular docking of compounds of F12 of ethyl acetate extract of Astraeus asiaticus with BcL2 and Caspase 3
Published 2025-02-01“…The mechanism of anticancer effect of F12 (AAEAE) on cancer cell lines included induction of apoptosis, LDH leakage, and up regulation of gene expression levels of Caspase 3, Caspase 9, P53, and down regulation of BcL2 of all three cell lines. …”
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57
Identification of RNA Editing Sites Reveals Functional Modifications with the Addition of Methionine to the Daily Rations of Yaks
Published 2025-01-01“…This provides further understanding of the mechanism of yak muscle tissue and regulation of gene expression after the addition of methionine to daily rations.…”
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58
<i>METTL3</i> and <i>FTO</i> Regulate Heat Stress Response in Hu Sheep Through Lipid Metabolism via m6A Modification
Published 2025-01-01“…In the lipid deposition heat stress model of preadipocytes, the regulation of gene expression was similar to that in hepatocytes.…”
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59
Reconstruction and computational analysis of the microRNA regulation gene network in wheat drought response mechanisms
Published 2025-01-01“…Wheat adaptation to water deficit is ensured by complex molecular genetic mechanisms, including the coordinated work of multiple genes regulated by transcription factors and signaling non-coding RNAs, particularly microRNAs (miRNAs). miRNA-mediated regulation of gene expression is considered one of the main mechanisms of plant resistance to abiotic stresses. …”
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Cooperative mechanisms of LexA and HtpG in the regulation of virulence gene expression in Pseudomonas plecoglossicida
Published 2025-01-01“…Our previous research suggested that LexA might collaboratively regulate virulence gene expression with HtpG during infection. This study aims to elucidate the molecular mechanism by which LexA controls virulence gene expression. …”
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