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  1. 13761
  2. 13762

    Mechanism of Exogenous Silicon in Enhancing Cold Stress Tolerance in <i>Solanum lycopersicum</i> L. Seedlings: Insights from Resistance and Quality Indicators by Fan Zhang, Yihong Zhao, Yuanbo Zhang, Yu Shi, Leiping Hou, Abid Khan, Ruixing Zhang, Yi Zhang

    Published 2024-12-01
    “…The results show that compared with the control treatment, the plant height, stem diameter, and fresh weight of above-ground and underground parts of tomato seedlings decreased significantly by 46.52%, 42.53%, 28.81%, and 28.97%, respectively, after 15 days of low-temperature stress (<i>p</i> < 0.05), and in order to resist low temperature, the activity of antioxidant enzymes and the content of osmotic adjustment substances were up-regulated in seedlings. Ultimately, low-temperature stress inhibited the morphological growth, nutritional quality, and yield of fruits. …”
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  3. 13763

    Predictive role of SLC1A5 in neuroblastoma prognosis and immunotherapy by Jian Cheng, Miaomiao Sun, Xiao Dong, Yang Yang, Xiaohan Qin, Xing Zhou, Yongcheng Fu, Yuanyuan Wang, Jingyue Wang, Da Zhang

    Published 2025-01-01
    “…Additionally, SLC1A5 negatively regulated ST8SIA1, a gene crucial for GD2 biosynthesis, suggesting that SLC1A5 inhibition may enhance GD2-directed immunotherapies. …”
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  4. 13764

    Analisis Kinerja Augmented Reality HyperText Markup Language (ARHTML) Melalui Pemanfaatan Web Graphics Library dan OpenGl Shading Language untuk Pengembangan 3D by Multohadi Hamzaturrazak, Abdul Jabbar, Rizal Setya Perdana, Aryo Pinandito

    Published 2024-10-01
    “…WebGL serves as the authoritative standard for 3D graphical rendering within web-based interfaces, whereas GLSL functions as the scripting language responsible for regulating the visual presentation produced by WebGL. …”
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  5. 13765

    Exosomes Derived from Mesenchymal Stem Cells Ameliorate Hypoxia/Reoxygenation-Injured ECs via Transferring MicroRNA-126 by Qunwen Pan, Yan Wang, Qing Lan, Weiquan Wu, Zhenxuan Li, Xiaotang Ma, Liming Yu

    Published 2019-01-01
    “…Stem cell-released exosomes (EXs) could modulate target cell functions by delivering their cargos, and exert therapeutic effects as their mother cells. miR-126 is an important regulator of EC functions and angiogenesis. In this study, we determined whether EXs released from MSC-EXs provided beneficial effects on hypoxia/reoxygenation- (H/R-) injured ECs by transferring miR-126. …”
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  6. 13766

    Four weeks of slow-paced breathing: a longitudinal, randomized, placebo-controlled study of the autonomic nervous system by Nicolas Bourdillon, Arnaud Rochat, Vanessa Hoop, Grégoire P. Millet

    Published 2025-01-01
    “… Introduction The autonomic nervous system (ANS) relies on two essential feedback loops: respiratory sinus arrythmia (RSA) and arterial baroreflex which are both regulated by a complex interplay of sympathetic and parasympathetic activations. …”
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  7. 13767

    AGD1/USP10/METTL13 complexes enhance cancer stem cells proliferation and diminish the therapeutic effect of docetaxel via CD44 m6A modification in castration resistant prostate can... by Hong Wang, Chunli Cui, Weiyi Li, Hui Wu, Jianjun Sha, Jiahua Pan, Wei Xue

    Published 2025-01-01
    “…Additionally, liposomal-chitosan nanocomplex drug delivery systems were designed to explore AGD1’s role in regulating docetaxel treatment resistance in CRPC. Results AGD1 expression was upregulated in PCSCs and exosomes. …”
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  8. 13768

    MAZ-mediated tumor progression and immune evasion in hormone receptor-positive breast cancer: Targeting tumor microenvironment and PCLAF+ subtype-specific therapy by Gaofeng Ni, Yuwei Sun, Hongling Jia, Zhikai Xiahou, Yumeng Li, Fu Zhao, Hongyan Zang

    Published 2025-02-01
    “…MAZ, identified as a key regulator, contributed to tumor progression, while the tumor microenvironment had a pivotal identity in immune evasion. …”
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  9. 13769

    Bifurcation analysis of multistability and hysteresis in a model of HIV infection by I. V. Mironov, M. Yu. Khristichenk, Yu. M. Nechepurenko, D. S. Grebennikov, G. A. Bocharov

    Published 2023-12-01
    “…HIV-1 control efforts with reliance on immunotherapy remain at a conceptual stage due to the complexity of a set of processes that regulate the dynamics of infection and immune response. …”
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  10. 13770

    Rescue of Mutant CFTR Channel Activity by Investigational Co-Potentiator Therapy by Mafalda Bacalhau, Filipa C. Ferreira, Marcelo Folhadella M. F. Azevedo, Talita P. Rosa, Camilla D. Buarque, Miquéias Lopes-Pacheco

    Published 2025-01-01
    “…<b>Background:</b> The potentiator VX-770 (ivacaftor) has been approved as a monotherapy for over 95 cystic fibrosis (CF)-causing variants associated with gating/conductance defects of the CF transmembrane conductance regulator (CFTR) channel. However, despite its therapeutic success, VX-770 only partially restores CFTR activity for many of these variants, indicating they may benefit from the combination of potentiators exhibiting distinct mechanisms of action (i.e., co-potentiators). …”
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  11. 13771
  12. 13772

    CEST imaging combined with 1H-MRS reveal the neuroprotective effects of riluzole by improving neurotransmitter imbalances in Alzheimer’s disease mice by Yuanyu Shen, Xiaolei Zhang, Siqi Liu, Lijing Xin, Wentao Xuan, Caiyu Zhuang, Yue Chen, Beibei Chen, Xinhui Zheng, Renhua Wu, Yan Lin

    Published 2025-01-01
    “…Conclusions CEST imaging combined with 1H-MRS demonstrated the effectiveness of riluzole in modulating Glu- and GABA-related changes and improving cognitive function in 3xTg AD mice, potentially through regulating key proteins involved in neurotransmitter metabolism. …”
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  13. 13773

    miR-26a-5p Attenuates Oxidative Stress and Inflammation in Diabetic Retinopathy through the USP14/NF-κB Signaling Pathway by Jie Bian, Weizhong Ge, Zhengmei Jiang

    Published 2024-01-01
    “…Moreover, miR-26a-5p targeted USP14 and inversely regulated USP14 expression. Additionally, HG-evoked activation of NF-κB signaling was suppressed by USP14 knockdown or miR-26a-5p upregulation. …”
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  14. 13774

    Radiogenomics and machine learning predict oncogenic signaling pathways in glioblastoma by Abdul Basit Ahanger, Syed Wajid Aalam, Tariq Ahmad Masoodi, Asma Shah, Meraj Alam Khan, Ajaz A. Bhat, Assif Assad, Muzafar Ahmad Macha, Muzafar Rasool Bhat

    Published 2025-01-01
    “…Disruptions in various oncogenic signaling pathways, such as Receptor Tyrosine Kinase (RTK)-Ras-Extracellular signal-regulated kinase (ERK) signaling, Phosphoinositide 3- Kinases (PI3Ks), tumor protein p53 (TP53), and Neurogenic locus notch homolog protein (NOTCH), contribute to the development of different tumor types, each exhibiting distinct morphological and phenotypic features that can be observed at a microscopic level. …”
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  15. 13775

    Designing a Conceptual model for Evaluating the Performance of Software Developers in Fintech Organizations by Hassan Javadi, Fereshteh Amin

    Published 2024-11-01
    “…These sub-themes, listed in order of priority, include teamwork, quality of produced software, customer satisfaction, documentation skills, participation in knowledge sharing, commitment to scheduling, mastery of production tools, participation in goal realization, compliance with organizational regulations, adherence to technical standards, problem-solving ability, and frequency of software rewriting. …”
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  16. 13776

    Effect of Whole Wheat Noodles on Biochemical Indexes and Histopathology of Type 2 Diabetic Rats by Li WU, Yuan ZHANG, Chunhong TANG, Huan YOU, Haijun CHANG, Shuai ZHANG

    Published 2025-02-01
    “…Conclusion: Whole wheat noodle has a significant intervention effect on type 2 diabetes mellitus, manifested in slowing down weight loss, lowering blood glucose values, regulating lipid metabolism and oxidative stress levels in the body, eliminating inflammatory edema in the organs, and restoring cellular damage of the organs in several ways.…”
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  17. 13777

    Analisis Penerimaan Learning Management System Institut Teknologi Garut Menggunakan Technology Acceptance Model by Asri Mulyani, Dede Kurniadi, Mita Hidayani Putri

    Published 2023-08-01
    “…In addition to complying with government regulations, the Garut Institute of Technology academic community also follows the development of interactive information technology-based education with the use of informative applications through electronic media in order to get efficient results, namely the Learning Management System. …”
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  18. 13778

    Longitudinal genetic studies of cognitive characteristics by R. N. Mustafin, A. V. Kazantseva, R. F. Enikeeva, S. B. Malykh, E. K. Khusnutdinova

    Published 2020-03-01
    “…The data on the correlation between transgenerational epigenetic inheritance of cognitive abilities and the insert of transposable elements in intergenic regions is discussed. Transposons regulate genes functioning in the brain due to the processing of their transcripts into non-coding RNAs. …”
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  19. 13779

    Exploring anticancer, antioxidant, and antimicrobial potential of Aspergillus flavus, a fungal endophyte isolated from Dillenia indica leaf callus by Ashish Gupta, Brajesh Chandra Pandey, Mohd Yaseen, Renu Kushwaha, Madhavenda Shukla, Pratima Chaudhary, Partha Pratim Manna, Aparna Singh, Ida Tiwari, Gopal Nath, Nishi Kumari

    Published 2025-02-01
    “…Methods: For callus initiation, leaf tissues of Dillenia indica were inoculated on Murashige and Skoog's medium supplemented with BAP (1mgl-1) and NAA (1mgl-1) plant growth regulators. To raise pure cultures of endophyte, fungal hyphae were isolated from the contaminated cultures and were grown on Potato Dextrose Agar medium. …”
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  20. 13780

    Upregulated astrocyte HDAC7 induces Alzheimer-like tau pathologies via deacetylating transcription factor-EB and inhibiting lysosome biogenesis by Jinwang Ye, Suyue Zhong, Huali Wan, Xing Guo, Xuanbao Yao, Qiong Liu, Liming Chen, Jian-Zhi Wang, Shifeng Xiao

    Published 2025-01-01
    “…However, the precise role of autophagy lysosomal signaling in astrocytes that regulates tau pathology remains unclear. Methods We investigated the expression of class IIa HDAC7 in astrocytes from AD patients and PS19 mice. …”
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