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13601
Effects of ursolic acid on growth performance, serum biochemistry, antioxidant capacity, and intestinal health of broilers
Published 2025-01-01“…In conclusion, adding 450 mg/kg UA to broiler feed can improve serum and jejunal antioxidant capacity, reduce jejunal and ileal inflammation, improve jejunal morphology, and regulate caecal microbiota structure composition, promoting broiler growth.…”
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13602
Letecká báze na Českomoravské vysočině
Published 2009-06-01“… The signing of the Munich Pact at the end of September 1938 did not only signify the demise of the first Czechoslovak Republic, but it also brought an end to a range of policies and regulations that Czechoslovakia had adopted in the second half of the 1930s in order to prepare for a potential conflict with Nazi Germany. …”
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13603
Synergistic effects of Vachellia nilotica-derived zinc oxide nanoparticles and melatonin on drought tolerance in Fragaria × ananassa
Published 2025-01-01“…ZnO NPs enhance nutrient uptake and stress resistance, while MT regulates growth hormones and boosts photosynthetic efficiency. …”
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13604
Visfatin Induces Inflammation and Insulin Resistance via the NF-κB and STAT3 Signaling Pathways in Hepatocytes
Published 2019-01-01“…Visfatin-induced inflammation and insulin resistance were regulated by JAK2/STAT3 and IKK/NF-κB signaling; together with AG490 or Bay 7082, visfatin significantly reduced mRNA levels of IL-6, TNF-α and IL-1β and rescued insulin signaling. …”
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13605
Single-Cell RNA-Seq Uncovers Cellular Heterogeneity from Deep Fascia in Necrotizing Fasciitis Patients
Published 2025-01-01“…Furthermore, the levels of SAA1, PTX3, S100 family, MARCO, and STAB1 were up-regulated in different subclusters with anti-infection roles against NF, which were proven by immunohistochemistry. …”
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13606
Clinical relevance of macromolecular complexes involving integrins, potassium and sodium ion channels and the sodium/proton antiporter in human breast cancer
Published 2025-01-01“…A complex composed by β1 integrin, hERG1 K+ channel, the neonatal form of the Na+ channel NaV 1.5 (nNaV1.5) and the Na+/H+ antiporter NHE1 (NHE1/hERG1/β1/nNaV1.5 complex) has been recently described to be expressed and regulate relevant cancer related behaviors in Breast Cancer (BCa) cells. …”
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13607
Altered CD73-Adenosine Signaling Linked to Infection in Patients undergoing hemodialysis
Published 2025-01-01“…The enzyme CD73, a cell surface 5′-nucleotidase, regulates the balance between pro-inflammatory nucleotides and anti-inflammatory adenosine. …”
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13608
Variations of microbiota and metabolites in rhizosphere soil of Carmona microphylla at the co-contaminated site with polycyclic aromatic hydrocarbons and heavy metals
Published 2025-01-01“…Some key bacterial taxa are resistant to HMs in rhizosphere soils, whereas they are susceptible to complex contamination in non-rhizosphere soils, which could be a consequence of the rhizosphere by regulating soil metabolism. It also provides a valuable reference for how co-contaminants and rhizosphere effect shape together soil bacterial community through the changes of soil metabolites.…”
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13609
Nicotine-induced CHRNA5 activation modulates CES1 expression, impacting head and neck squamous cell carcinoma recurrence and metastasis via MEK/ERK pathway
Published 2024-10-01“…Nicotine exposure activates CHRNA5, regulating CES1 expression via the MEK/ERK pathway, contributing to the recurrence and metastasis of head and neck squamous carcinoma.…”
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13610
The Roles of Skin Fibroblasts at Local Acupoints in Chrono-Acupuncture
Published 2020-01-01“…The aim of this study was to demonstrate the peripheral mechanisms of chrono-acupuncture by observing acupuncture at different time points affecting relative proteins to regulate the cytoskeleton of fibroblasts differently. …”
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13611
LncRNA GAS5 inhibits glioma progression through miR-135b-5p/APC axis
Published 2025-02-01“…Western blotting and qRT-PCR indicated that GAS5 was down-regulated in the glioma cell lines and tissues than human normal astrocytes and para-cancer tissues (P<0.01). …”
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13612
Relationship between the ideal and reality in civil service: retrospective approach towards ethical problems in the interwar Lithuanian Republic
Published 2011-06-01“…Lithuanian legislator, earlier than scientists, tried to introduce the model for civil servants, emphasizing certain aspects of their activity or indicating some restrictions. The first laws regulating the activity of civil servants were passed as far back as 1919 and 1920. …”
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13613
Identification of SETD4 as an Onco‐Immunological Biomarker Encompassing the Tumor Microenvironment, Prognoses, and Therapeutic Responses in Various Human Cancers
Published 2025-01-01“…ABSTRACT Background SET domain‐containing protein 4 (SETD4) is a histone methyltransferase that has been shown to modulate cell proliferation, differentiation, and inflammatory responses by regulating histone H4 trimethylation (H4K20me3). Previous reports have demonstrated its function in the quiescence of cancer stem cells as well as drug resistance in several cancers. …”
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13614
Neuronal density in the brain cortex and hippocampus in Clsnt2-KO mouse strain modeling autistic spectrum disorder
Published 2022-07-01“…Our new findings indicate that calsyntenin-2 regulates neuronal hippocampal density in subfield-specific manner, suggesting that the CA1 neuronal subpopulation may represent a cellular target for earlylife preventive therapy of ASD.…”
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13615
Homologous recombination deficiency test validation in patients with high-grade advanced ovarian cancer
Published 2025-02-01“…Our in-house assay is eligible for diagnostic test approval and market access as per Brazilian regulations.…”
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13616
Effects of Negative Pressure Wound Therapy on Levels of Angiopoetin-2 and Other Selected Circulating Signaling Molecules in Patients with Diabetic Foot Ulcer
Published 2019-01-01“…We assessed NPWT’s effect on the plasma levels of angiopoietin-2 (Ang2), a key regulator of angiogenesis, and its microvesicular receptors (Tie2) as well as the microvesicles (MVs) themselves in DFU patients. …”
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13617
The Mla pathway promotes Vibrio cholerae re-expansion from stationary phase
Published 2025-02-01“…Additional mechanistic studies support the idea that the Mla pathway is critical for maintaining the culturability of V. cholerae because it promotes energy homeostasis, likely due to its role in regulating outer membrane vesicle shedding. Together our findings provide insights into the cellular processes that control re-expansion from stationary phase and demonstrate a previously undiscovered role for the Mla pathway.IMPORTANCEBacteria regularly encounter conditions with nutrient scarcity, where cell growth and division are minimal. …”
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13618
The Influence of Digital Talent Development and Green Innovation and The Use of Green Innovation As Mediation To Measure Data Centre Performance
Published 2025-01-01“…Telkom Group faces the biggest challenges in data centre development in the form of compliance with increasingly stringent sustainability regulations, increasing demand for skilled and experienced talent, as well as the challenge of adopting green innovation as a solution to sustainability issues. …”
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13619
Evaluating a novel team learning approach for integrating drugs in sports education in preclinical medical training
Published 2025-02-01“…The session aimed to introduce fundamental concepts of performance-enhancing drugs, anti-doping regulations, and patient communication strategies within the context of sports medicine. …”
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13620
Xiaohua Funing decoction ameliorates non-alcoholic fatty liver disease by modulating the gut microbiota and bile acids
Published 2025-02-01“…In addition, glycochenodeoxycholic acid was identified as a potential biomarker of NAFLD.DiscussionIn summary, our experiments revealed that XFD regulates the gut microbiota and BAs, providing beneficial effects on liver lipid accumulation in NAFLD.…”
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