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  1. 13461

    Effect of feedback-integrated reflection, on deep learning of undergraduate medical students in a clinical setting by Zainab Maqsood, Madiha Sajjad, Raheela Yasmin

    Published 2025-01-01
    “…Abstract Background Reflection fosters self-regulated learning by enabling learners to critically evaluate their performance, identify gaps, and make plans to improve. …”
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    Article
  2. 13462

    Obesity-induced mesenteric PVAT remodelling is sexually dimorphic, but not driven by ovarian hormones by Lisa Ivatt, Mhairi Paul, Allende Miguelez-Crespo, Patrick W. F. Hadoke, Matthew A. Bailey, Ruth A. Morgan, Mark Nixon

    Published 2025-01-01
    “…Perivascular adipose tissue (PVAT), a metabolically active tissue surrounding blood vessels, plays a key role in regulating vascular tone. In obesity, PVAT becomes dysregulated which may contribute to vascular dysfunction; how sex impacts the remodelling of PVAT and thus the altered vascular contractility during obesity is unclear. …”
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  3. 13463

    Hepatocyte Rho-associated kinase signaling is required for mice to survive experimental porphyria-associated liver injury by Jessica M. Herrera, Yun Weng, Tyler J. Lieberthal, Marcus Paoletti, Tammy T. Chang

    Published 2025-02-01
    “…Rho-associated kinases 1 and 2 (ROCK1 and ROCK2) regulate critical cell functions, including actomyosin contractility, apoptosis, and proliferation. …”
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  4. 13464

    Determinación de la absorción de agua de una pieza termoplástica modular impresa = Determination of water absorption of a printed modular thermoplastic part by Sandra Moyano-Sanz, Amparo Verdú-Vázquez, Mercedes Valiente-López

    Published 2022-12-01
    “…Abstract In this work, the results obtained in the laboratory tests, referring to the determination of water absorption, of a printed modular thermoplastic piece and two pieces of fired clay are analyzed and compared with the values stipulated in the current regulations and the documentation of declaration of corresponding benefits. …”
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    Article
  5. 13465

    Dietary and plasma atherogenic and thrombogenic indices and cardiometabolic risk factors among overweight and individuals with obesity by Reyhaneh Mokhtari, Mahdieh Abbasalizad Farhangi

    Published 2025-02-01
    “…Conclusion This research introduces a novel field of investigation and emphasizes the possible importance of TI, AI, and AIP indices in regulating cardiometabolic risk factors.…”
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    Article
  6. 13466

    The Performance of Irrigation Schemes in Sudan Affected by Climate Variability and the Grand Ethiopian Renaissance Dam by Shamseddin M. Ahmed, Khalid G. Biro Turk, Hassan Ali Dinar

    Published 2025-01-01
    “…However, the construction of the Grand Ethiopian Renaissance Dam (GERD) in the Blue Nile at the Sudan border has changed water flow regulations along the Blue Nile. Therefore, the Sudanese irrigation schemes that depend on the Blue Nile are affected by the operation and management of the GERD. …”
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  7. 13467

    Pharmacological effects of fibroblast growth factor 21 are sex-specific in mice with the <em>lethal yellow</em> (A<sup>y</sup>) mutation by E. N. Makarova, T. V. Yakovleva, N. Yu. Balyibina, K. O. Baranov, E. I. Denisova, A. D. Dubinina, N. A. Feofanova, N. M. Bazhan

    Published 2020-04-01
    “…Hypothalamic melanocortin 4 receptors (MC4R) regulate energy balance. Mutations in the MC4R gene are the most common cause of monogenic obesity in humans. …”
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    Article
  8. 13468

    Paeoniflorin alleviates sepsis-associated acute kidney injury in mice by inhibiting aerobic glycolysis through the β-catenin/c-Myc pathway by GONG Yu, LEI Jiao, ZHANG Ming

    Published 2025-01-01
    “…PF treatment attenuated the renal tissue damage, decreased Paller score (P<0.05), reduced serum Scr and NGAL levels (P<0.05), HK2, LDHA and serum lactate levels, and contents of IL-1β and IL-18 in renal tissues (P<0.05), and down-regulated the renal expression of total β-catenin, p-β-cateninY654, nucleus β-catenin and c-Myc when compared with the levels in the model group (P<0.05). …”
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  9. 13469

    miR-576-5p Promotes the Proliferation of Papillary Thyroid Carcinoma through the MAPK4-AKT Pathway by Rui Hai, Yang Zhou, Fan Li, Qingxi Guo, Yang Long, Fang Wang, Lian Cheng, Fei Wu, Shi Chen, Xiangyu Zhou

    Published 2022-01-01
    “…Expression levels of mitogen-activated protein kinase 4 (MAPK4) and phosphorylation levels of protein kinase B (AKT), extracellular regulated protein kinase (ERK), and P38 mitogen-activated protein kinase (P38) were detected by western blotting or immunohistochemistry (IHC). …”
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  10. 13470

    Biological characteristics of bream (Abramis brama Linnaeus, 1758) of the Kremenchuk Reservoir as an object of commercial fishery by N. Rudyk-Leuska, O. Buzevych, M. Leuskyi, I. Burjak

    Published 2024-12-01
    “…The obtained data were used to adjust the limits for the harvest of aquatic biological resources of the Kremenchuk Reservoir and fishery regimes in terms of regulating the fishing effort for 2025.…”
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    Article
  11. 13471

    Nucleotide sequence variants, gene expression and serum profile of immune and antioxidant markers associated with brucellosis resistance/susceptibility in Shami goat by Ahmed A. Elsayed, Ahmed M. Sallam

    Published 2025-01-01
    “…Levels of gene expression of SLC11A1, TLR1, TLR9, SP110, ADORA3, CARD15, IRF3, HMOX1, TKT, RPIA and AMPD were significantly (P < 0.05) up regulated in the infected compared to the non-infected ones. …”
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  12. 13472

    Spatial and seasonal distribution of selected nitrogen cycle genes in deep waters of the Baltic Proper by Michał Grabski, Michał Grabski, Ewa Kotlarska, Aneta Łuczkiewicz, Konrad Hryniewicz, Grzegorz Węgrzyn, Beata Szymczycha

    Published 2025-02-01
    “…Marine nitrogen cycle ultimately depends on the biological responses of oceanic microbial communities. It indirectly regulates primary production and influences the strength of the biological pump, which contributes to the oceanic uptake of atmospheric carbon dioxide (CO2). …”
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  13. 13473

    Genome-wide microsatellite characterization and their marker development and transferability in Broussonetia Species by Xiaowen Jia, Hanyu Li, Ying Han, Lu Wang, Chanjuan Lai, Xi Liu, Pan Li, Zupei Lei, Yonghua Zhang

    Published 2025-01-01
    “…Genic-mapped SSRs may regulate biological processes by influencing gene activity and protein function. …”
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  14. 13474

    Perancangan dan Pembuatan Sistem Informasi Retensi Rekam Medis Rawat Jalan di Puskesmas Jenggawah Kabupaten Jember by Andri Permana Wicaksono, Muhaiminul Aziz, Feby Erawantini, Ida Nurmawati

    Published 2022-08-01
    “…The result of this study is an outpatient medical record retention information system that has the ability to regulate and manage the retention, preservation, and destruction of outpatient medical record documents and is integrated with the information system for borrowing and returning medical record documents so that it can make it easier for officers to carry out retention activity at Jenggawah Public Health Center. …”
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  15. 13475

    Design and Dynamic Analysis of Ideological and Political Education Platform Based on Network Multimedia Technology by Xiaowen Chen

    Published 2022-01-01
    “…Because of the thought-political education platform design and ideological dynamic analysis of network multimedia technology, this study analyzes the construction and teaching circumstances of the platform, and then uses principal component analysis to analyze students’ political theory, political attitude, civilized etiquette, observance of thought, collective thought, public welfare thought, analysis of learning ideas, get the eigenvalues and variance %, of which the proportion of variance of the first four principal components exceeds 90%; public welfare activities and the idea of abiding by laws and regulations have a better influence on the first main component; collective thinking has a comparison on the impact of the second principal component, the correlation between the indicators of thought-political education and the concept of students’ quality is greater than 0.75; it shows that each index has a large degree of correlation with the concept of students’ quality, among which Political attitudes have the greatest impact on students’ quality outlook, with a correlation coefficient of 0.911; secondly, using a nonhomogeneous hidden Markov model to analyze ideological dynamics, we can get the learning situation in different ideological states; finally, the hot spots during the epidemic are related to ideological dynamics Sexual analysis showed that the p values were all less than 0.05, and the correlation analysis between hotspots and ideological dynamics during the epidemic was significant, namely “national sentiments”, “social responsibility”, “angels in white”, “Chinese power”, and “the benevolence of doctors”. …”
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  16. 13476

    PEDAGOGICAL CONTENT THREE-FACTOR MODEL OF EDUCATING HIGH-SCHOOL STUDENTS FOR PROFESSIONAL ACTIVITIES by T. A. Lopatukhina, A. V. Rynkevich

    Published 2016-09-01
    “…The methods involve the analysis of a condition of higher education and the provisions of the Federal Law on Education regulating its functioning in the Russian Federation; text-centered approach to education of the person of culture – the professional specialist, responsible for the activities.Results and scientific novelty. …”
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  17. 13477

    Achievements and prospects of applying high-throughput sequencing techniques to potato genetics and breeding by I. V. Bykova, N. A. Shmakov, D. A. Afonnikov, A. V. Kochetov, E. K. Khlestkina

    Published 2017-03-01
    “…The Potato Genome Sequencing Consortium activities included not only constructing genome libraries, sequencing, assembling and annotation of the genome, but also genome sequence-based investigations uncovering features of potato genome evolution, SNP identification, analysis of genes and gene networks regulating resistance to phytopathogens and technological characteristics. …”
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    Article
  18. 13478

    DLAT is involved in ovarian cancer progression by modulating lipid metabolism through the JAK2/STAT5A/SREBP1 signaling pathway by Hui Wang, Shen Luo, Yue Yin, Yang Liu, Xiaomei Sun, Ling Qiu, Xin Wu

    Published 2025-01-01
    “…Western blot analysis was performed to determine whether the JAK2/STAT5 signaling pathway was involved in DLAT-regulated SREBP1 expression. Commercially available triglyceride and cholesterol detection kits, as well as Nile Red and Oil red O staining were used to measure lipid metabolism. …”
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    Article
  19. 13479

    PLCG2 and IFNAR1: The Potential Biomarkers Mediated by Immune Infiltration and Osteoclast Differentiation of Ankylosing Spondylitis in the Peripheral Blood by Bo Han, Qiaobo Xie, Weishi Liang, Peng Yin, Xianjun Qu, Yong Hai

    Published 2024-01-01
    “…Dysregulation of PLCG2 and IFNAR1 are key factors in disease occurrence and development of AS through regulating immune infiltration and osteoclast differentiation. …”
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    Article
  20. 13480

    Comparative analysis of the whole transcriptome landscapes of muscle and adipose tissue in Qinchuan beef cattle by Ju Qiu, Zheng Ma, Zhipeng Hong, Xu Yin, Yun Chen, Hafiz Qadeer Ahmed, Linsen Zan, Anning Li

    Published 2025-01-01
    “…Abstract Background Muscle and adipose tissue are the most critical indicators of beef quality, and their development and function are regulated by noncoding RNAs (ncRNAs). However, the differential regulatory mechanisms of ncRNAs in muscle and adipose tissue remain unclear. …”
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