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13141
Epigenetic Biomarkers and the Wnt/β-Catenin Pathway in Opisthorchis viverrini-associated Cholangiocarcinoma: A Scoping Review on Therapeutic Opportunities.
Published 2024-09-01“…<h4>Background</h4>Epigenetic modifications, such as DNA methylation and histone modifications, are pivotal in regulating gene expression pathways related to inflammation and cancer. …”
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13142
Some Problems of the Realization of Marital Relation with Foreigners
Published 2021-07-01“…It has been noted that marital and family relations are regulated by separate legislative acts and in some countries by religious norms. …”
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13143
Extracellular Vesicles in Periodontitis: Pathogenic Mechanisms and Therapeutic Potential
Published 2025-01-01“…Conversely, extracellular vesicles derived from dental stem cells (DSCs) have demonstrated the ability to regulate the local periodontal immune environment and foster the regeneration and repair of periodontal tissues, positioning them as a promising candidate for cell-free therapeutic approaches to periodontitis. …”
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13144
QUALITY EVALUATION OF THE TPP POWER GENERATING UNITS WEAR RECONDITIONING
Published 2016-02-01“…In practical work these constraints give place to essential ambiguity of the decision. Further to regulating techniques by way of informational support, the authors propose conducting the wear-reconditioning quality evaluation (repair quality) accordingly the technical-and-economic indexes pattern of change. …”
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13145
Paediatric Contacts of Adult COVID-19 Patients: Clinical Parameters, Risk Factors, and Outcome
Published 2021-01-01“…Parents with higher education and in the health profession and the families of symptomatic contacts reported better compliance with quarantine regulations. Conclusion. A significant number of children were exposed to adult COVID-19 patients. …”
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13146
Effects of Baicalin on Gout Based on Network Pharmacology, Molecular Docking, and in vitro Experiments
Published 2025-02-01“…The results of cell experiments suggested that baicalin could reduce the levels of inflammatory cytokines by inhibiting the TLR4/NF-κB signaling pathway in MSU-stimulated THP-1 cells and regulate the expression of these hub targets.Conclusion: These results revealed that baicalin possesses “multitarget, multipathway, multilevel” regulatory effects. …”
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13147
Psychometric Properties of the Arabic Version of the Pain Resilience Scale among Lebanese Adults with Chronic Musculoskeletal Pain
Published 2024-01-01“…The Pain Resilience Scale (PRS), which measures behavioral perseverance and the ability to regulate emotions and cognition despite ongoing pain, lacks an Arabic version. …”
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13148
How the Suboxone Education Programme presented as a solution to risks in the Canadian opioid crisis: a critical discourse analysis
Published 2022-07-01“…Within this context, this study examined how the ‘Suboxone Education Programme’, developed and delivered by a pharmaceutical company as part of a federally regulated risk management program, was presented as a solution to various kinds of risks relating to opioid use in public documents from medical institutions across Canada.Setting These documents were issued during the Canadian opioid crisis, a time when the involvement of industry in health policy was being widely questioned given industry’s role in driving the overprescribing of opioid analgesics and contributing to population-level harms.Design A critical discourse analysis of 69 documents collected between July 2020 and May 2021 referencing the Suboxone Education Program spanning 13 years (2007–2021) from medical, nursing and pharmacy institutions sourced from every Canadian province and territory. …”
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13149
MEG3 Alleviated LPS-Induced Intestinal Injury in Sepsis by Modulating miR-129-5p and Surfactant Protein D
Published 2020-01-01“…These findings indicated that MEG3 might be a potential target for intestinal damage caused by sepsis via regulating miR-129-5p and SP-D.…”
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13150
Mechanisms linking river flow regime and riparian hardwood establishment
Published 2025-01-01“…Further, under both reservoir‐controlled and unimpaired flow regimes, establishment was strongly determined by post‐deposition flow increases: seeds deposited at elevations low enough to support rooting were often killed via inundation or scour in flow fluctuations that occurred under both reservoir‐regulated and unregulated flow scenarios. When soil moisture dynamics are represented even simply, the survivable rate of stage decline is not constant but depends on capillary fringe height, seed elevation, and the duration of stage decline. …”
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13151
Genetic sources for barley (<i>Hordeum vulgare</i>) breeding in the Volga-Vyatka region
Published 2019-06-01“…General principles regulating selection of initial genotypes for barley tissue culture were formulated. …”
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13152
Investigating the effect of driven length and diameter of monopile on seismic performance of offshore wind turbines through Physical Modeling
Published 2024-12-01“…Monopiles, cylindrical hollow piles with diameters ranging from 2 to 8 meters and lengths of approximately 60 meters, are widely used to install offshore wind turbines. The design regulations for these turbines often overlook influential factors such as soil-structure interaction and refer to seismic design guidelines for onshore turbines. …”
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13153
The Golden Afromontane ecosystems at cross-road: Wetland-based upstream-downstream linkage in Genale Dawa River Basin
Published 2025-01-01“…Although provisioning ESV has increased, regulating, supporting, and cultural ESVs have experienced significant losses. …”
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13154
The Association between Hepcidin and Iron Status in Children and Adolescents with Obesity
Published 2021-01-01“…It is postulated that inflammation increases hepcidin, a regulator of iron homeostasis. The aim of this study was to investigate the associations between iron status, hepcidin, and BMI-standard deviation score (BMI-SDS) in children with and without obesity. …”
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13155
Spaciotemporal distribution characteristics of glacial lakes and the factors influencing the Southeast Tibetan Plateau from 1993 to 2023
Published 2025-01-01“…Glacial lakes play a crucial role in regulating the freshwater ecosystems of the region, but they also pose a significant threat to local infrastructure and populations due to flooding caused by glacial lake outbursts. …”
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13156
The Different Insulin-Sensitising and Anti-Inflammatory Effects of Palmitoleic Acid and Oleic Acid in a Prediabetes Model
Published 2022-01-01“…Although the effects of palmitoleic acid (POA) are still debated, POA can regulate glucose homeostasis, lipid metabolism, and cytokine production, thus improving metabolic disorders. …”
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13157
Identification of GPD1L as a Potential Prognosis Biomarker and Associated with Immune Infiltrates in Lung Adenocarcinoma
Published 2023-01-01“…In this study, following an examination of the TGCA datasets, we found that GPD1L displayed a dysregulated state in a wide variety of cancers; this led us to believe that GPD1L is an essential regulator in the progression of malignancies. In addition, we found that the expression of GPD1L was much lower in LUAD tissues when compared with nontumor specimens. …”
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13158
Exploring the Hepatoprotective Effect of Agaricus bisporus Based on Network Pharmacology
Published 2025-01-01“…These results confirmed the predictions, indicating that ABEE might exert its hepatoprotective effect by regulating the expression of Bcl-2, MYC, NF-κB1 and RELA through salicylic acid, palmitic acid, linolenic acid, and chrysin, as well as their associated signaling pathways such as chemical carcinogenesis-receptor activation. …”
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13159
Internal transcribed spacer metagenomics data unravelling the core fungal community structure residing the wheat and maize rhizosphereNCBINCBINCBI
Published 2025-02-01“…The microbial communities exert a significant influence on the vigor, growth, development and productivity of plants by supporting nutrient acquisition, organic matter decomposition and tolerance against biotic and abiotic stresses such as heat, high salt, drought and disease, by regulating plant defense responses. The rhizosphere is a complex micro-ecological zone in the direct vicinity of plant roots and is considered a hotspot of microbial diversity. …”
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13160
Modern classification and molecular-genetic aspects of osteogenesis imperfecta
Published 2020-04-01“…In the last decade, it has become known that autosomal recessive, autosomal dominant and X-linked mutations in a wide range of genes, encoding proteins that are involved in the synthesis of type I collagen, its processing, secretion and post-translational modification, as well as in proteins that regulate the differentiation and activity of bone-forming cells, cause imperfect osteogenesis. …”
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