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12901
Solving the choice puzzle: Financial and non-financial stakeholders preferences in corporate disclosures
Published 2023-12-01“…This study establishes a connection between firms’ unconventional and less traditional activities, such as CSP, and conservative financial reporting, offering valuable insights for investors, analysts, and regulators. AcknowledgmentThis paper is co-funded by the European Union through the European Education and Culture Executive Agency (EACEA) within the project “Embracing EU corporate social responsibility: challenges and opportunities of business-society bonds transformation in Ukraine” – 101094100 – EECORE – ERASMUS-JMO-2022-HEI-TCH-RSCH-UA-IBA / ERASMUS-JMO-2022-HEI-TCHRSCH https://eecore.snau.edu.ua/…”
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12902
MiR-128-3p mediates MRP2 internalization in estrogen-induced cholestasis through targeting PDZK1
Published 2025-02-01“…Emerging evidence indicates that PDZ domain containing 1 (PDZK1) regulates localization of MRP2; however, PDZK1’s role and regulatory machinery in MRP2-mediated estrogen-induced cholestasis (EIC) remain unclear. …”
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12903
Microstructure Evolution and Mechanical Properties of B<sub>4</sub>C-Reinforced TC11 + xFe Composites Fabricated by HIP
Published 2025-01-01“…In addition, the optimal overall properties can be achieved by strictly regulating the addition ratio of 2 wt% Fe and 1 wt% B<sub>4</sub>C, allowing for a compressive strength of 2301 MPa while still maintaining a compressive strain of 24.6%.…”
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12904
Hypoxia signature derived from tumor-associated endothelial cells predict prognosis in gastric cancer
Published 2025-01-01“…EPAS1 was a VWF trans-regulated gene and highly positively correlated with VWF in expression. …”
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12905
Natural factors outweigh anthropogenic impact on aquatic phoD-harboring communities along Yangtze River basin
Published 2025-01-01“…The bacterial communities encoding alkaline phosphatase (phoD) gene (phoD-harboring communities hereafter), play essential roles in regulating organic phosphorus (P) mineralization in aquatic ecosystems. …”
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12906
Influences of non-uniformly distributed forming loads on deformation sequence and texture evolution in tailor heat treated Al6014 blanks
Published 2025-01-01“…In this study, to address these issues, a control strategy that utilizes non-uniformly distributed pressure (NUDP) to regulate the regional deformation behaviors of tailor heat treated blank (THTB) is proposed. …”
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12907
Programmed cell death-related gene IL20RA facilitates tumor progression and remodels tumor microenvironment in thyroid cancer
Published 2025-01-01“…Abstract Programmed cell death (PCD) is a vital biological process that is essential for regulating cell progression and tumor microenvironment. …”
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12908
Overexpression of HIF-2α, TWIST, and CXCR4 Is Associated with Lymph Node Metastasis in Papillary Thyroid Carcinoma
Published 2013-01-01“…TWIST and CXCR4 mRNA expression levels were up-regulated in PTCs, and high mRNA expression of TWIST and CXCR4 was significantly correlated with LNM (P=0.005 and P=0.010, resp.). …”
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12909
Lipid Coating Modulates Effects of Nanoceria on Oxidative Metabolism in Human Embryonic Lung Fibroblasts: A Case of Cardiolipin
Published 2025-01-01“…The unique redox properties of nanoscale cerium dioxide determine its diverse application in biology and medicine as a regulator of oxidative metabolism. Lipid modifiers of the nanoparticle surface change their biochemical properties and bioavailability. …”
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12910
Polydatin-Induced Shift of Redox Balance and Its Anti-Cancer Impact on Human Osteosarcoma Cells
Published 2024-12-01“…Analysis of the oxidative stress regulators SIRT1 and Nrf2 at the gene and protein levels using real-time PCR and Western blot indicates an early oxidative response to PD treatment. …”
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12911
Variations in the Obesity Gene “LEPR” Contribute to Risk of Type 2 Diabetes Mellitus: Evidence from a Meta-Analysis
Published 2016-01-01“…Leptin is a hormone protein regulating food intake and energy expenditure. A number of studies have evaluated the genetic effect of leptin (LEP) and leptin receptor (LEPR) genes on T2DM. …”
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12912
Anti-Neuroinflammatory Effects of Prenylated Indole Alkaloids from the Antarctic Fungus <i>Aspergillus</i> sp. Strain SF-7367
Published 2025-01-01“…Results of Western blotting and molecular docking showed that brevianamide K could regulate the activation of nuclear factor kappa-light-chain-enhancer of activated B cell (NF-κB) signaling. …”
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12913
The Anti-Inflammatory Effects of Shinbaro3 Is Mediated by Downregulation of the TLR4 Signalling Pathway in LPS-Stimulated RAW 264.7 Macrophages
Published 2018-01-01“…Three mechanisms explaining the effects of Shinbaro3 in RAW 264.7 cells were identified as follows: (1) inhibition of the extracellular signal-regulated kinase 1 and 2 (ERK1/2), stress-activated protein kinase (SAPK)/c-Jun N-terminal protein kinase (JNK), and p38 mitogen-activated protein kinase (MAPK) pathways; (2) suppression of IκB kinase-α/β (IKK-α/β) phosphorylation and nuclear factor-kappa B (NF-κB) subunits in the NF-κB pathway, which are involved in MyD88-dependent signalling; and (3) downregulation of IFN-β mRNA expression via inhibition of interferon regulatory factor 3 (IRF3) and Janus-activated kinase 1 (JAK1)/signal transducer and activator of transcription 1 (STAT1) phosphorylation, which is involved in TRIF-dependent signalling. …”
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12914
Efficient hydrogen peroxide reduction in glutathione peroxidase cycle using cost-effective FeSe2 nanospheres
Published 2025-01-01“…IntroductionHydrogen peroxide plays a crucial role in melanogenesis by regulating tyrosinase activity, the key melanin-forming enzyme responsible for the browning of fruits, vegetables, and seafood. …”
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12915
Pengaruh Gaya Kepemimpinan Situasional, Motivasi dan Kompensasi Terhadap Produktivitas Kerja Karyawan
Published 2024-09-01“…Background: The competition in the business world is so tight, but the development of manufacturing companies that are increasingly showing that the positive trend is related to the role of leaders who are figures who regulate the company's operational system. HR work productivity will increase through the implementation of the impact program of leadership style, appropriate compensation. …”
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12916
Exploring bio-remediation strategies by a novel bacteria Micrococcus sp. strain HX in Cr(VI)-contaminated groundwater from long-term industrial polluted
Published 2025-01-01“…Transcriptome analyses revealed oxidoreductase activity, ATP binding and the NAD(P) binding region protein-related gene expression were up-regulated. Binding reduction experiments indicated that most of the Cr(III) was detected extracellular, which suggests that the reduction of Cr(VI) by HX was mainly extracellular enzyme-catalyzed.…”
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12917
Dryland fungi are spatially heterogeneous and resistant to global change drivers
Published 2024-12-01“…Abstract Fungi are considered particularly important in regulating the structure and function of dryland ecosystems, yet the response of dryland fungal communities to global change remains notably understudied. …”
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12918
Integrated omics revealed the altered colonic microenvironment after inhibition of peripheral serotonin synthesis by LP533401
Published 2024-12-01“…Abstract Gut‐derived 5‐hydroxytryptamine (5‐HT), known as serotonin, plays a crucial role in regulating gastrointestinal functions. However, the impact of disruptions in gut‐derived 5‐HT synthesis on the early gut microbiome and intestinal microenvironment remains unclear. …”
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12919
ERK5 Contributes to VEGF Alteration in Diabetic Retinopathy
Published 2010-01-01“…We investigated a novel pathway, namely extracellular signal regulated kinase 5 (ERK5) mediated signaling, in modulating glucose-induced vascular endothelial growth factor (VEGF) expression. …”
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12920
Peripheral blood miRNAs are associated with airflow below threshold in children with asthma
Published 2025-01-01“…Abstract Background MicroRNAs (miRNAs) are crucial post-transcriptional regulators involved in inflammatory diseases, such as asthma. …”
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