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12661
Design of retrofit flue gas (CO2) scrubber for dependable clean energy at the Duvha Coal Power Plant
Published 2024-10-01“…The goal of this work is to design a CO2 flue gas cleaning retrofit system that will meet the most stringent air quality regulations in an operational coal power station in Southern Africa. …”
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12662
Dihydromyricetin inhibits injury caused by ischemic stroke through the lncRNA SNHG17/miR-452-3p/CXCR4 axis
Published 2025-01-01“…The protective effects of DHM were found to be mediated through the downregulation of SNHG17, which in turn modulated miR-452-3p expression. miR-452-3p was identified as a negative regulator of pro-inflammatory CXCR4, a direct target whose expression was inversely affected by SNHG17. …”
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12663
Changes in IL-16 Expression in the Ovary during Aging and Its Potential Consequences to Ovarian Pathology
Published 2022-01-01“…The expression of IL-16, frequency of macrophages (a source of IL-16) and expression of microRNA (miR) 125a-5p (a regulator of IL-16 gene) were performed by immunohistochemistry, immunoblotting, and gene expression assays. …”
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12664
Technological innovation, trade openness, natural resources, clean energy on environmental sustainably: a competitive assessment between CO2 emission, ecological footprint, load ca...
Published 2025-02-01“…The study recommends that BRICS + T nations prioritize investments in green technologies, strengthen environmental regulations, and enhance international collaboration to accelerate the transition to renewable energy. …”
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12665
Deer antler velvet (Cervus elaphus sibiricus) promotes fracture healing via partial BMP2-Smad mediated osteoblast differentiation
Published 2025-01-01“…CES administration also significantly upregulated the expression of TGF-β1 day 7, BMP 2, and osterix day 14 at the fracture site and also up-regulated alkaline phosphatase (ALP) activity, calcium deposition, and the phosphorylation of Smad in MG63 cells. …”
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12666
Dynamics of REL, RELA and IRF1 transcription factor expression in U937 macrophages after dioxin exposure
Published 2017-02-01“…Macrophages are key regulators of the innate immune response, as well as one of the first types of cells which respond to chemical stress, so the study of the action of TCDD on these cells is important. …”
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12667
Definition and content of the concept of transparency of criminal justice
Published 2022-09-01“…On the basis of the analysis of criminal procedural norms that reveal the content of the principles of publicity and openness, suggestions have been made regarding: 1) increasing the degree of legal certainty of the norms that regulate the procedure for consideration by the investigating judge of a request for the conduct of secret investigative (search) actions; 2) it is necessary to take into account that the list of grounds provided for in Art. 27 of the Criminal Procedure Code of Ukraine, is not exhaustive, and/or to provide for the grounds indicated in this article, or to indicate that other cases provided for by the Criminal Procedure Code of Ukraine are possible. …”
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12668
A Novel Role for Brain Natriuretic Peptide: Inhibition of IL-1β Secretion via Downregulation of NF-kB/Erk 1/2 and NALP3/ASC/Caspase-1 Activation in Human THP-1 Monocyte
Published 2017-01-01“…Identifying molecules modulating their expression is a crucial need to develop new therapeutic agents. IL-1β is a strong regulator of Brain Natriuretic Peptide (BNP), a hormone involved in cardiovascular homeostasis by guanylyl cyclase Natriuretic Peptide Receptor (NPR-1). …”
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12669
Counteraction corruption under martial law: an analysis of problems and opportunities
Published 2024-06-01“…The beginning of the full-scale invasion of russia led not only to significant financial problems in Ukraine, but also to an increase in the level of corruption, which led to active actions by the state to counteract it. State bodies that regulate corruption manifestations are considered, as well as the normative and legal framework for combating corruption in the conditions of martial law in Ukraine is analyzed, with the determination of opportunities in this area. …”
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12670
Administrative legal relations with the participation of the State Bureau of Investigation
Published 2024-03-01“…It is emphasised that these are mainly intra-organisational relations within these bodies, since their purpose is to counteract crimes committed by law enforcement officers, judges and senior civil servants, i.e. their external activities are generally not managerial and are not regulated by administrative and legal provisions.…”
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12671
Characterization of gene expression profiles in Alzheimer's disease and osteoarthritis: A bioinformatics study.
Published 2025-01-01“…However, to confirm the effectiveness of these genes as therapeutic targets, more in-depth mechanistic studies are needed in the future, particularly to explore the feasibility and specific mechanisms of combating disease progression by regulating the expression of these genes.<h4>Conclusions</h4>This study suggests that AD and OA shares common molecular mechanisms. …”
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12672
Starch metabolism in potato <i>Solanum tuberosum</i> L.
Published 2022-06-01“…It is a complex process, requiring the orchestrated work of many enzymes, transporter and targeting proteins, transcription factors, and other regulators. Two types of starch are recognized with regard to their biological functions. …”
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12673
Decoding CKD-induced muscle atrophy through the critical role of lncRNA GAS5 and pyroptosis
Published 2025-03-01“…Our findings provide new evidence for GAS5’s role in regulating cellular pyroptosis in CKD-induced skeletal muscle atrophy.…”
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12674
LEBIH DARI SEKADAR TREN: PENGARUH FOMO (FEAR OF MISSING OUT), PERBANDINGAN SOSIAL, DAN MATERIALISME PADA PERILAKU BUY NOW PAY LATER GEN Z
Published 2025-01-01“…Its implications include the need for regulations to manage BNPL responsibly and business opportunities to leverage this trend.…”
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12675
Network pharmacology combined with experimental verification for exploring the potential mechanism of phellodendrine against depression
Published 2025-01-01“…PHE exerted an anti-MDD effect by regulating SLC6A4, SLC6A3, SLC6A2, MAOA and other targets through serotonergic synapse, salivary secretion, dopaminergic synapse, and cAMP signalling pathway. …”
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12676
Introduction of the Project “Community Police Officer” as a Step towards Strengthening Local Security Infrastructure
Published 2020-02-01“…The author has emphasized on the importance of developing Regulations on the organization of community police officers’ work and developing an effective mechanism for elaborating the training programs for community police officers.…”
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12677
Therapeutic potential of targeting the IRF2/POSTN/Notch1 axis in nucleus pulposus cells for intervertebral disc degeneration
Published 2025-01-01“…IRF2 was identified as a regulator of POSTN at the transcriptional level, contributing to NLRP3 activation and NP cell pyroptosis. …”
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12678
Gastronomy vs gastro-anomie? Japan’s foodscape
Published 2024-10-01“…Nowadays, washoku is the institutional foundation for a specialized legislative act regulating the procedure of Re-McDonaldization of the population. …”
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12679
Investigating the role of hyperexpressed HCN1 in inducing myocardial infarction through activation of the NF-κB signaling pathway
Published 2024-12-01“…In conclusion, PDTC provided protection against HCN1-induced cardiomyocyte injury, potentially by modulating inflammatory cytokines and regulating the IKKβ/IκB/NF-κB signaling pathway.…”
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12680
Wogonin Inhibits Cardiac Hypertrophy by Activating Nrf-2-Mediated Antioxidant Responses
Published 2021-01-01“…To further explore the role of nuclear factor- (erythroid-derived 2-) like 2 (Nrf-2) in regulating the antioxidant effects of Wog in cardiac hypertrophy, siRNA analysis was conducted. …”
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