An Efficiency Optimized Direct Model Predictive Control of Induction Machine Drive by Adeola Balogun, Sodiq Agoro, Sunday Adetona, Ayobami Olajube, Frank Okafor

“…Discrete dynamic model of the induction machine is applied in stationary reference frame with pre-set present and past reference values of the speed and rotor flux for generating the stator current references The uniqueness of the MPC proposed herein is that it does not require outer cascade proportional plus integral (PI) controllers used for regulating rotor speed and flux. Elimination of the outer loop cascade is made possible in this article by the introduction of a unique four-term cost function comprising of weighted magnitudes of the errors between four measured state variables and their reference commands.  …”
Get full text

Psychiatric disorders in children and adolescents with temporal lobe epilepsy: A narrative review by Pietro Cappelletto, Claudia Accolla, Martina Preti, Tiziana Pisano, Carmen Barba, Renzo Guerrini

“…Psychiatric disorders associated with temporal lobe epilepsy are relatively frequent, probably in relation to the critical role that some limbic structures in the temporal lobe, such as the amygdala and hippocampus, play in regulating emotions and behavior.…”
Get full text

The relative risk of fatal poisoning by methadone or buprenorphine within the wider population of England and Wales by Dave Marteau, Rebecca McDonald, Kamlesh Patel

“…Clinicians should be aware of the increased risk of prescribing methadone, and tighter regulations are needed to prevent its diversion.…”
Get full text

Data on the administrative workload and perceived administrative burden of farmers in SwitzerlandZenodo by Gabriele Mack, Christian Ritzel, Jeanine Ammann, Katja Heitkämper, Nadja El Benni

“…Finally, the results showed that 28 % of the Swiss farmers had received a penalty for non-compliance with direct payment regulations.…”
Get full text

miR-197 Participates in Lipopolysaccharide-Induced Cardiomyocyte Injury by Modulating SIRT1 by Miaomiao Liu, Ying Zhang, Xiantong Cao, Tao Shi, Yang Yan

“…Subsequently, silent information regulator 1 (SIRT1) was downregulated in H9c2 cells to explore its interaction with miR-197 under LPS induction. …”
Get full text

Immunopathology of Airway Surface Liquid Dehydration Disease by Brandon W. Lewis, Sonika Patial, Yogesh Saini

“…In this disease, a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene results in dehydration of the airway surface liquid (ASL) layer. …”
Get full text

Effects of levothyroxine therapy on bone and mineral metabolism in hypothyroidism: a systematic review and meta-analysis by Xiaotao Li, Taotao Zhang, Hongling Zhang, Shanshan Liu, Limin Tian

“…Abstract Background Thyroid hormone plays an important role in accumulating bone development and regulating bone metabolism. It is established that hypothyroidism is linked to increased risk of osteoporosis and fracture. …”
Get full text

HIF-3α-Induced miR-630 Expression Promotes Cancer Hallmarks in Cervical Cancer Cells by Forming a Positive Feedback Loop by Qiaohui Gao, Zhenghua Ren, Shengyuan Jiao, Juan Guo, Xia Miao, Jin Wang, Junye Liu

“…But we know little about how the hypoxia factors and microRNAs orchestrate to regulate hallmarks of cervical cancer cells. Methods. …”
Get full text

Legal aspects of protecting the Ukrainian population against emergencies under martial law by O. A. Lukianykhina, S. A. Petrovska

“…The introduction of martial law on the territory of Ukraine affects the civil defence system in terms of the legal framework and the process of organising disaster protection, which is manifested in the following 1) in addition to the Civil Protection Code of Ukraine No. 5403-VI of 2 October 2012 and departmental by-laws in the field of civil protection of the population from emergencies, an extra legal basis appears in the form of the Decree of the President of Ukraine on the introduction of martial law, the provisions of which may define additional tasks in the field of civil defence; ensure the implementation of functions on protection of the population from emergencies; 2) the structure of public administration is changed, which provides for the establishment of military administrations, which, in cooperation with the military command, ensure coordination of public authorities, in particular those responsible for the protection of the population from emergencies; 3) during the legal regime of martial law, it is allowed to involve citizens of Ukraine in socially useful works carried out to eliminate man-made, natural and military emergencies that occurred during martial law and their consequences It is noted that the procedure for engaging representatives of the categories specified in the Resolution of the Cabinet of Ministers of Ukraine “On Approval of the Procedure for Engaging Able-bodied Persons in Socially Useful Work under Martial Law” needs to be clarified at the level of individual by-laws and regulations at the level of peculiarities of their collection, notification, management of their activities, disciplinary liability and the system of payment of remuneration in cash or in kind, non-material incentives, their institutionalisation and methodological basis for organising and conducting such work.…”
Get full text

Roles of Copper Transport Systems Members in Breast Cancer by Yichang Chen, Chen Li, Mengxin Li, Bing Han

“…Both copper deficiency and excess can inhibit breast cancer growth, while copper transport systems may contribute to its progression by regulating copper ion transport and the activity of associated proteins. …”
Get full text

Options of dyslipidemia treatment at non-alcoholic fatty liver disease by M. V. Mayevskaya, M. A. Morozova

“…These substances play important role in lipid metabolism regulating expression of the genes (including PPARα) involved in lipid and glucose metabolism. …”
Get full text

The Effectiveness of Interaction between Scientific Supervisors and Graduate Students at the University and at the Academy of Sciences by E. V. Biricheva, Z. A. Fattakhova

“…The solution of this set of problems seems to be based, first of all, on a new regulatory framework at the federal level, revising the types and volumes of workload of graduate students and their supervisors, fixing the need to write a dissertation during the course of study, regulating the requirements for scientific supervisors and guaranteeing them advanced training in the field managerial competencies. …”
Get full text

The opposite association of HRAS and KRAS mutations with clinical variables of bladder cancer by M. P. Smal, A. I. Rolevich, T. N. Nabebina, S. A. Krasny, R. I. Goncharova

“…HRAS, KRAS and NRAS gene products belong to the superfamily of small GTPases. These proteins regulate cellular response to extracellular stimuli by means of activation of different signaling pathways. …”
Get full text

Downregulation of PGC-1α Prevents the Beneficial Effect of EET-Heme Oxygenase-1 on Mitochondrial Integrity and Associated Metabolic Function in Obese Mice by Shailendra P. Singh, Lars Bellner, Luca Vanella, Jian Cao, John R. Falck, Attallah Kappas, Nader G. Abraham

“…EET is identified as an upstream positive regulator of PGC-1α that leads to increased HO-1, decreased BW and fasting blood glucose and increased insulin receptor phosphorylation, that is, increased insulin sensitivity and mitochondrial integrity, and possible use of EET-agonist for treatment of obesity and metabolic syndrome.…”
Get full text

Objective Features of Administrative Offenses under the Article 443 of the Code of Ukraine on Administrative Offenses and Their Impact on the Scope of Powers of the National Police... by V. V. Krykun

“…The author has established the content of a socially dangerous act, which stipulates administrative liability under the Art. 433 of the Code of Ukraine on Administrative Offenses: 1) violation of the rules provided by the Resolution of the Cabinet of Ministers of Ukraine “On the prevention of the spread of an acute respiratory disease COVID-19 caused by the corona virus SARS-CoV-2 on the territory of Ukraine” dated from March 11, 2020 No. 211; 2) violation of the requirements of regulatory acts (orders, instructions, rules, regulations, etc.) of the Ministry of Health, which establish sanitary-hygienic and sanitary-anti-epidemic rules. …”
Get full text

The cell cycle regulatory gene polymorphisms TP53 (rs1042522) and MDM2 (rs2279744) in lung cancer: a meta-analysis by O. Bulgakova, A. Kussainova, R. Bersimbaev

“…The tumor suppressor p53 plays a crucial role in maintaining genomic stability and tumor prevention. MDM2 is a critical regulator of the p53 protein. Despite the importance of p53 pathway in cancer, data on the contribution of SNPs of TP53 (rs1042522) and MDM2 (rs2279744) to the development of lung cancer are very contradictory. …”
Get full text

Approaches to ecological sustainability in sub-Saharan Africa: Evaluating the role of globalization, renewable energy, economic growth, and population density by Abdikafi Hassan Abdi, Siyad Abdirahman Siyad, Mohamed Okash Sugow, Omar Mohamed Omar

“…Based on these findings, the study recommends that SSA countries prioritize investments in renewable energy infrastructure, adopt stricter environmental regulations, embrace green technologies to promote sustainable economic growth and leverage urbanization and infrastructure development.…”
Get full text

Uninvestigated Dyspepsia and Heartburn Overlap Syndrome at Industrial Hub of Eastern Siberia by V. V. Tsukanov, A. V. Vasiutin, J. L. Tonkikh, E. V. Kasparov, O. V. Smirnova

“…Each participant signed an informed examination consent, in accordance to the regulations by the World Medical Association’s Declaration of Helsinki. …”
Get full text

‘There’s a Little Bit of Tension There’: perspectives of mothers and early childhood educators on breast-feeding in child care centers by Jill R Demirci, Rachel Dieterich, Melissa Glasser, Caroline Harpel, Timothy Shope

“…EC educators’ capacity to offer breast-feeding support was constrained by CCC infant feeding regulations, inadequate breast-feeding training and time limitations. …”
Get full text

Phytochemical composition and antioxidant properties of Canarium odontophyllum (Sarawak Olive): A seasonal fruit from Borneo, East Malaysia by Gilbert Ringgit, Bo Eng Cheong, Muhammad Dawood Shah, Shafiquzzaman Siddiquee

“…Other health-beneficial compounds were also found, such as palmitic amide (2.46 %), deoxymiroestrol (6.23 %), and N-Cyclohexanecarbonylpentadecylamine (48.92 %), which are important in preventing metal corrosion, regulating hormones, and distinguishing between N-palmitoylethanolamine-hydrolyzing acid amidase (NPAA) and fatty acid amide hydrolase (FAAH), respectively. …”
Get full text