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12521
Dorsal Root Ganglion Maintains Stemness of Bone Marrow Mesenchymal Stem Cells by Enhancing Autophagy through the AMPK/mTOR Pathway in a Coculture System
Published 2018-01-01“…Moreover, the autophagy level of BMSCs, regulating their stemness, was promoted in the coculture group, mediated by the AMPK/mTOR pathway. …”
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12522
Lachnospiraceae-bacterium alleviates ischemia-reperfusion injury in steatotic donor liver by inhibiting ferroptosis via the Foxo3-Alox15 signaling pathway
Published 2025-12-01“…Dysbiosis of the gut microbiota has been implicated in modulating IRI, and Lachnospiraceae plays a pivotal role in regulating host inflammatory and immune responses, but its specific role in liver transplantation IRI remains unclear. …”
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12523
Organic Light-Emitting Diode with Color Tunable between Bluish-White Daylight and Orange-White Dusk Hue
Published 2014-01-01“…The reason why the present device can effectively regulate the shifting of recombination zone is because the first emissive layer itself possesses an effective hole modulation barrier of 0.2 eV. …”
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12524
Probiotic Characterization of Lactic Acid Bacteria from Donkey Feces in China
Published 2025-01-01“…Probiotics are beneficial to humans and animals and often used for regulating immunity, intestinal microbiota balance, and animal growth performance. …”
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12525
Soil microbiome interventions for carbon sequestration and climate mitigation
Published 2025-01-01“…ABSTRACT Mitigating climate change in soil ecosystems involves complex plant and microbial processes regulating carbon pools and flows. Here, we advocate for the use of soil microbiome interventions to help increase soil carbon stocks and curb greenhouse gas emissions from managed soils. …”
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12526
CTSG is a prognostic marker involved in immune infiltration and inhibits tumor progression though the MAPK signaling pathway in non-small cell lung cancer
Published 2024-12-01“…Transcriptome sequencing and subsequent bioinformatic analysis were performed to explore the signaling pathways regulated by CTSG. Western blotting and qPCR were utilized to assess the influence of CTSG on the MAPK and EMT signaling pathways. …”
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12527
Astragaloside IV inhibits atherosclerosis caused by ferritin autophagy in a lipid deposition environment by activating Nrf2
Published 2025-03-01“…Collectively, these findings suggest that astragaloside IV can regulate autophagy-dependent NCOA4 and FTH1 expression through activation of Nrf2, thereby inhibiting autophagy.…”
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12528
Conductive polymers and derivatives as recognition element for electrochemical sensing of food and drug additives: A brief perspective
Published 2025-01-01“…Conducting polymers (CPs) are a distinct category of polymeric materials characterised by conjugated main chains that display adjustable electrical and optical properties. By regulating their doping states, these characteristics can be enhanced for many applications. …”
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12529
Adenosine cyclic phosphate with ultrasonic-assisted pectinase extraction alleviated allergic reactions in RBL-2H3 through inhibiting the influx of intracellular Ca2+
Published 2023-05-01“…Our results demonstrate that jujube cAMP regulated the cytokine balance in the allergy pathway through blocking the influx of extracellular Ca2+, with the prevention of allergy symptoms.…”
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12530
Restriction Enzyme Analysis of DNA Methylation in “Condensed” Chromatin of Ha-Ras-Transformed NIH 3T3 Cells
Published 2000-01-01“…Since DNA methylation is likely to be involved in regulating the nucleosomal level of DNA packaging, we studied the role of DNA methylation in higher‐order chromatin organization induced by Ha‐ras. …”
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12531
Injectable Hierarchical Bioactive Hydrogels with Fibroblast Growth Factor 21/Edaravone/Caffeic Acid Asynchronous Delivery for Treating Parkinson's Disease
Published 2025-01-01“…., reduction the loss of tyrosine hydroxylase in substantia nigra compacta and striatum (retained ≈10‐fold versus control), decreasing oxidative stress, reducing astrocyte and microglia activation, and stimulating the AMPK/PGC‐1α axis to regulate the mitochondrial function, providing a multi‐dimensional PD therapy. …”
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12532
Intravenous Transplantation of Mesenchymal Stem Cells Reduces the Number of Infiltrated Ly6C+ Cells but Enhances the Proportions Positive for BDNF, TNF-1α, and IL-1β in the Infarct...
Published 2018-01-01“…The resident microglial and infiltrating cells from peripheral circulation are involved in the pathological processes of ischemia stroke and may be regulated by mesenchymal stem/stromal cell (MSC) transplantation. …”
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12533
Current challenges, and potential solutions to increase acceptance and long-term consumption of cultured meat and edible insects – A review
Published 2025-06-01“…Likewise, non-product barriers such as familiarity, neophobia, cultural context, and government regulations influence consumer acceptance. This review will provide a consolidated update on the current challenges faced by cultured meats and insects, two upcoming and trending alternative proteins, and give a holistic view of consumer acceptance in terms of product quality as well as external non-product barriers. …”
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12534
Simulating responses of riparian ecosystem network complexity to flow regime shifts in arid regions
Published 2025-01-01“…The study’s methodology and findings provide a scientific foundation for developing comprehensive management guidelines to regulate riparian areas under global change.…”
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12535
Identification of dominant species of submerged vegetation based on Sentinel-2 red-edge band: A case study of Lake Erhai, China
Published 2025-02-01“…Aquatic vegetation plays a crucial role as a primary producer and ecological regulator, serving as an indispensable purifier in inland lakes. …”
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12536
ANKRD22 participates in the proinflammatory activities of macrophages in the colon cancer tumor microenvironment
Published 2025-02-01“…Our previous study suggested that ANKRD22 may play a role in regulating the functional state transition of macrophages. …”
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12537
circZNF532 promotes endothelial-to-mesenchymal transition in diabetic retinopathy by recruiting TAF15 to stabilize PIK3CD
Published 2024-07-01“…This study explored the role of circRNA zinc finger protein 532 (circZNF532) in regulating EndMT in DR progression. Human retinal microvascular endothelial cells (HRMECs) were exposed to high glucose (HG) to induce the DR cell model. …”
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12538
GPX4 expression changes in proximal tubule cells highlight the role of ferroptosis in IgAN
Published 2025-01-01“…Subsequent enrichment analysis revealed that the differentially expressed genes associated with OS in PTCs were primarily linked to the process of ferroptosis. Therefore, regulators of ferroptosis were collected to define the ferroptosis activity of PTCs in IgAN, and we found that the activity of suppressing ferroptosis was significantly enhanced. …”
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12539
Expression of Interferon Effector Gene SART1 Correlates with Interferon Treatment Response against Hepatitis B Infection
Published 2016-01-01“…Mechanistically, silencing SART1 abrogated the antiviral activity of IFN-α, reduced the expression of IFN-stimulated genes (ISGs) Mx, OAS, and PKR, and attenuated JAK-STAT signaling in HepG2 cells, suggesting that SART1 regulates IFN-mediated antiviral activity through JAK-STAT signaling and ISG expression. …”
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12540
Stimulation of TLR4 by LMW-HA Induces Metastasis in Human Papillary Thyroid Carcinoma through CXCR7
Published 2013-01-01“…In inflammatory sites, high molecular weight hyaluronan fragments are degraded into lower molecular weight hyaluronan fragments (LMW-HA) to regulate immune responses. However, the function of LMW-HA in PTC progression remains to be elucidated. …”
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