Circulating Levels of Betatrophin and Irisin Are Not Associated with Pancreatic β-Cell Function in Previously Diagnosed Type 2 Diabetes Mellitus Patients by Lingshu Wang, Jun Song, Chuan Wang, Peng Lin, Kai Liang, Yu Sun, Tianyi He, Wenjuan Li, Ruxing Zhao, Jun Qin, Yiran Lu, Jinbo Liu, Fuqiang Liu, Xinguo Hou, Li Chen

“…Betatrophin and irisin are two recently identified hormones which may participate in regulating pancreatic β-cell function. However, the associations of these two hormones with β-cell function remain unclear. …”
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Electroacupuncture Mitigates Hippocampal Cognitive Impairments by Reducing BACE1 Deposition and Activating PKA in APP/PS1 Double Transgenic Mice by Yinshan Tang, Shujun Shao, Yu Guo, You Zhou, Jin Cao, Anping Xu, Jihong Wu, Zhigang Li, Dulian Xiang

“…In summary, EA treatment might reduce BACE1 deposition in APP/PS1 transgenic mice and regulate PKA and its associated substrates, such as LTP to change memory and learning abilities.…”
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Circulating Angiogenic Growth Factors in Diabetes Patients with Peripheral Arterial Disease and Exertional Leg Pain in Ghana by Kwame Yeboah, Jennifer A. Agyekum, Eric Kyei Baafour, Daniel A. Antwi, Afua B. Adjei, Vincent Boima, Ben Gyan

“…Peripheral arterial disease (PAD) is a common complication of diabetes, associated with impairment in angiogenesis. Angiogenesis is regulated by angiogenic growth factors such as angiopoietin 1 (Ang-1), Ang-2, and vascular endothelial growth factor (VEGF). …”
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Immunoreactivity of the SARS-CoV-2 entry proteins ACE-2 and TMPRSS-2 in murine models of hormonal manipulation, ageing, and cardiac injury by Susan Bengs, Alexia Rossi, Martina Haberecker, Nidaa Mikail, Alexander Meisel, Achi Haider, Muriel Grämer, Angela Portmann, Atanas Todorov, Christof Schönenberger, Caroline E. Gebhard, Gabriela M. Kuster, Vera Regitz-Zagrosek, Catherine Gebhard

“…Abstract Previous work indicates that SARS-CoV-2 virus entry proteins angiotensin-converting enzyme 2 (ACE-2) and the cell surface transmembrane protease serine 2 (TMPRSS-2) are regulated by sex hormones. However, clinical studies addressing this association have yielded conflicting results. …”
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Norcantharidin induces G2/M arrest and apoptosis via activation of ERK and JNK, but not p38 signaling in human renal cell carcinoma ACHN cells by Huang Shuaishuai, Tuergong Gulimire, Zhu Hangjie, Wang Xue, Weng Guobin, Ren Yu

“…Interestingly, NCTD treatment provoked the phosphorylation of extracellular-regulated protein kinase (ERK) and c-Jun-N-terminal kinase (JNK), but not of p38 MAPK. …”
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Urinary glucose detection with spiral shape hollow core photonic crystal fiber: Towards improved diabetes management by Md. Safiul Islam, A.H.M. Iftekharul Ferdous, Md. Jakir Hossen, Abdullah Al Mamun, Khalid Sifulla Noor, Diponkar Kundu, Md. Galib Hasan

“…Acute diabetes treatment and follow-up rely on urine glucose detection since it provides a non-invasive, reasonably priced means to assess glucose levels and regulate the progression of the disease. This article presents the development of a circular shape core and semi-circular trapezoid air holes biosensor PCF to assess the glucose concentration in urine inside the THz band. …”
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Dietary Lactiplantibacillus plantarum KX041 attenuates colitis-associated tumorigenesis and modulates gut microbiota by Tao Wang, Panpan Wang, Li Yin, Xiuchao Wang, Yuanyuan Shan, Yanglei Yi, Yuan Zhou, Bianfang Liu, Xin Wang, Xin Lü

“…In addition, treatment with L. plantarum KX041 could directly regulate gut microbiota, thereby increasing the abundance of beneficial bacteria (like SCFAs-producing bacteria, Akkermansia) and decreasing the abundance of harmful bacteria (like pro-inflammatory bacteria, Parasutterella), which in turn raised SCFAs levels and lowered LPS levels. …”
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RECQL4 requires PARP1 for recruitment to DNA damage, and PARG dePARylation facilitates its associated role in end joining by Mansoor Hussain, Prabhat Khadka, Komal Pekhale, Tomasz Kulikowicz, Samuel Gray, Alfred May, Deborah L. Croteau, Vilhelm A. Bohr

“…RECQL4 is involved in regulating major DNA repair pathways, such as homologous recombination and nonhomologous end joining (NHEJ). …”
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CC16 alleviates PM2.5-induced lung epithelial cell injury and airway inflammation in asthmatic mice by inhibiting ferroptosis by Aili Wang, Jianling Liu, Zhangwen Li, Ze Qian, Shuo Yang, Shaohua Luo, Jinle Lin, Jian Wu

“…Results: CC16 significantly modulated key regulators of ferroptosis (NRF2, GPX4, SLC7A11, HO-1) and attenuated pro-inflammatory cytokines (IL-13, IL-5, IL-6, IL-1β, IL-17A) in PM2.5-exposed lung epithelial cells. …”
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The Role of Dectin-1-Mediated M1 Macrophage Polarization in Cerebral Ischemia-Reperfusion Injury by Chen Zongyun, Lin Bixia, Ding Fadian, Hong Xiaoping, Chen Hongbin, Deng Yu, Liu Qicai, Ye Xiaoyi, Zeng Kai

“…Dectin-1 plays an important role in cerebral ischemia-reperfusion injury by regulating the function of immune cells. Methods. C57BL/6 was blindly divided into four groups including the sham-operated group and the three different kinds of middle cerebral artery occlusion (MCAO) groups (after 6 hours, 12 hours, and 24 hours after plug removal). …”
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Circadian Variation of Zinc, Copper, Selenium, and Bromine in Human Milk by Nor Hidayah Mohd Taufek, Hana’ Nahlaa Hafiz Majdi, Aina Zafirah Azhar, Abdul Rahman Fata Nahas, Awis Sukarni Mohmad Sabere, Joseph Bidai

“…This may indicate a functional circadian clock regulating infants’ biological development. Future studies should explore the factors influencing the development of fully functional circadian rhythmicity in infants. …”
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Downregulation of Thromboxane A2 Receptor Occurs Mainly via Nuclear Factor-KappaB Signaling Pathway in Rat Renal Artery by Yaping Zhang, Man Mi, Yan-Hua Xie, Si-Wang Wang, Lars Edvinsson, Cang-Bao Xu

“…Thromboxane A2 (TXA2) acts on TXA2 receptors (TP) to regulate renal artery blood flow and subsequently contributes to the pathogenesis of renal ischemia. …”
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PLGA confers upon conventional nonfluorescent molecules luminescent properties to trigger 1O2-induced pyroptosis and immune response in tumors by Lan Zou, Rujing Wang, Mengnan Zhao, Yuke Li, Chen Sun, Jinjin Xie, Yan Chen, Qian Jing, Dandan Mi, Sanjun Shi

“…Abstract Pyroptosis, a recently identified cellular demise regulated by gasdermin family proteins, is emerging as a promising avenue in cancer immunotherapy. …”
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Mechanism of engineered macrophage membrane bionic gene-carrying nanospheres for targeted drug delivery to promote wound repair in deep second-degree burns by Zhihan Zhu, Xinghua Zhu, Shichen Miao, Bolin Wang, Zihan Li, Dinghao Zhang, Shentian Zou, Yi Zhang, Qingrong Zhang, Kesu Hu

“…PCNA and HGF expression was significantly up-regulated in the HGF@ETMM@NPS group. The HGF@ETMM@NPS complex drug delivery system used in this research promoted wound healing via effective delivery of HGF to burn wounds, thereby accelerating skin cell growth and migration.…”
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Sodium Lactate Accelerates M2 Macrophage Polarization and Improves Cardiac Function after Myocardial Infarction in Mice by Jialiang Zhang, Fangyang Huang, Li Chen, Guoyong Li, Wenhua Lei, Jiahao Zhao, Yanbiao Liao, Yijian Li, Changming Li, Mao Chen

“…Sodium lactate facilitates anti-inflammatory M2 macrophage polarization and protects against MI by regulating P-STAT3.…”
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A Reduction in Selenoprotein S Amplifies the Inflammatory Profile of Fast-Twitch Skeletal Muscle in the mdx Dystrophic Mouse by Craig Robert Wright, Giselle Larissa Allsopp, Alex Bernard Addinsall, Natasha Lee McRae, Sofianos Andrikopoulos, Nicole Stupka

“…There is interest in characterising novel genes that regulate inflammation due to their potential to modify disease progression. …”
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MicroRNA-32-5p promotes the proliferation and metastasis of gastric cancer cells by Chao Sun, Lai-gang Huang, Bing Leng, Yanting Guo, Chen Chen, Ruijie Lv, Yan Dong, Tian-tian Gao, De-qing Sun

“…We concluded that miR-32-5p negatively regulated the DSC2 expression, might be a potential therapeutic targeting of cancers, most especially in GC.…”
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Corporate accreditation system of PJSC Gazprom as a tool for ensuring uniformity of measurements of organization by R. T. Saetova, I. A. Battalov, Ya. V. Denisova

“…Protection of the interests of the consumer and the rights of the supplier is ensured by the accuracy of determining the quantity and quality indicators of the supplied products established in technical regulations, standards and by minimizing risks to life, human health and the environment on the basis of reliable measurements. …”
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Alcohol Inhibits Odontogenic Differentiation of Human Dental Pulp Cells by Activating mTOR Signaling by Wei Qin, Qi-Ting Huang, Michael D. Weir, Zhi Song, Ashraf F. Fouad, Zheng-Mei Lin, Liang Zhao, Hockin H. K. Xu

“…Our findings show for the first time that EtOH can suppress DPC differentiation and mineralization in a mTOR-dependent manner, indicating that EtOH may be involved in negatively regulating the dental pulp repair.…”
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Tannins for food preservation and human health: A review of current knowledge by Yesim Ozogul, Yilmaz Ucar, Eskindir Endalew Tadesse, Nikheel Rathod, Piotr Kulawik, Monica Trif, Tuba Esatbeyoglu, Fatih Ozogul

“…Tannins also play a role in regulating plant growth and development, while having a protective function against ultraviolet radiation. …”
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