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12441
The myometrial transcriptome changes in mares with endometrosis
Published 2025-01-01“…In conclusion, transcriptomic alterations in the myometrium of mares with endometrosis may indicate an impaired function of the contractile machinery, mechanisms regulating calcium influx and handling, as well as changes in ECM composition, leading to a decreased contractile activity and structural changes in the myometrium of affected mares.…”
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12442
Targeting ferroptosis for improved radiotherapy outcomes in HPV‐negative head and neck squamous cell carcinoma
Published 2025-02-01“…To enhance the efficacy of radiotherapy (RT) in human papillomavirus (HPV)‐negative head and neck squamous cell carcinoma (HNSCC), we explored targeting ferroptosis, a regulated cell death process. We developed a gene signature associated with ferroptosis using Cox proportional hazard modeling in HPV‐negative HNSCC patients who underwent RT. …”
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12443
Renal Failure Associated with APECED and Terminal 4q Deletion: Evidence of Autoimmune Nephropathy
Published 2010-01-01“…Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is a rare autosomal recessive disorder caused by mutations in the autoimmune regulator gene (AIRE). Terminal 4q deletion is also a rare cytogenetic abnormality that causes a variable syndrome of dysmorphic features, mental retardation, growth retardation, and heart and limb defects. …”
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12444
Sulforaphane enhances Nrf2-mediated antioxidant responses of skeletal muscle induced by exhaustive exercise in HIIT mice
Published 2022-09-01“…ABSTRACT: Nuclear factor erythroid-derived 2-like 2 (Nrf2) is the master regulator of antioxidant defenses. High-intensity interval training (HIIT) has been proposed as a time-efficient training program and has become a substantial component of modern training program. …”
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12445
Improvement of organizational and methodological issues of analytical control of natural gas quality in Testing laboratory
Published 2021-09-01“…The basis of consumer confidence in the purchased products is ensured by the reliability of confirmation of the conformity of products established in the requirements of technical regulations and standards. Confirmation of the quality of products constantly requires the analytical laboratory to implement methods and techniques for monitoring the quality of analyzes. …”
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12446
1-Methylcyclopropene Delays Browning and Maintains Aroma in Fresh-Cut Nectarines
Published 2025-01-01“…The results indicated that 1-MCP restrained the soluble quinone (SQC) accumulation in fresh-cut nectarines by regulating the peroxidase (POD) and polyphenol oxidase (PPO) activities and the metabolism of phenolic compounds. …”
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12447
Integration of Metabolomics and Transcriptomics to Reveal the Antitumor Mechanism of <i>Dendrobium officinale</i> Polysaccharide-Based Nanocarriers in Enhancing Photodynamic Immuno...
Published 2025-01-01“…The transcriptomics analysis showed that 1352 genes were differentially expressed among the three groups. The differentially regulated functional pathways were primally related to the antitumor immune response. …”
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12448
The extraction of effective components and an antioxidant activity study of Tulipa edulis
Published 2024-01-01“…Meanwhile, the gene expression of heme oxygenase 1 (HO-1), γ-glutamyl cysteine ligase catalytic subunit (GCLC) and NAD(P)H quinone oxidoreductase-1 (NQO1) in HUVEC cells was up-regulated after treated with F2. This study provides reference value for the further development and application of T. edulis and the development of functional food.…”
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12449
Effect of IRAK-M on Airway Inflammation Induced by Cigarette Smoking
Published 2017-01-01“…IRAK-M, negatively regulating Toll-like receptor, is shown the dual properties in the varied disease contexts. …”
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12450
Multisensor Data Fusion and GIS-DRASTIC Integration for Groundwater Vulnerability Assessment With Rainfall Consideration
Published 2025-01-01“…Nitrate and TDS, the two reliable and recognized scientific water quality measurements, have been used to validate the model. By regulating and controlling anthropogenic and agricultural pollution, the danger of contamination can be decreased. …”
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12451
Anti-inflammatory Property of Galectin-1 in a Murine Model of Allergic Airway Inflammation
Published 2019-01-01“…These immunomodulatory effects in the allergic lung were correlated with the activation of extracellular signal-regulated kinase (ERK) signaling pathway and downregulation of endogenous Gal-1. …”
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12452
Comparative functional analysis of a new CDR1-like ABC transporter gene in multidrug resistance and virulence between Magnaporthe oryzae and Trichophyton mentagrophytes
Published 2025-02-01“…MoCdr1 and TmCdr1 are conserved in structures and functions, and both involved in drug resistance and pathogenicity by analogously regulating gene expression levels related to transporter activity, MAPK signaling pathway, and metabolic processes. …”
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12453
Enhancing maize seed resistance to chilling stress through seed germination and surface morphological changes using high voltage electrostatic field
Published 2025-02-01“…These results demonstrate that HVEF treatment enhances soluble sugar accumulation during seed germination, regulating osmotic balance within the cells. Furthermore, SEM assessed maize microtissue morphology after chilling injury and HVEF treatment. …”
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12454
Hypoxia inducible factor-dependent upregulation of Agrp in glomus type I cells of the carotid body
Published 2025-02-01“…Given the unexpected abundance of AgRP in glomus type I cells, a chemoreceptor cell specialized in oxygen sensing, we proceeded to investigate whether Agrp expression in the CB is regulated by hypoxemia and associated oxygen-sensing molecular mechanisms. …”
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12455
Functional poly(ether-ketone-ketone) composite scaffold with enhanced cell-material interaction, anti-inflammatory and osteogenesis for facilitating osteointegration and bone regen...
Published 2025-04-01“…Additionally, SPBC enhanced the adsorption of fibronectin and vitronectin on the scaffold surface and regulated the maturation of cytoskeleton and adhesion plaques by increasing the phosphorylation level of FAK at Y397, thereby promoting cell adhesion and spreading. …”
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12456
Serine/threonine protein kinase mediates rifampicin resistance in Brucella melitensis through interacting with ribosomal protein RpsD and affecting antioxidant capacity
Published 2025-01-01“…These findings demonstrate that the STPK gene mediates resistance by regulating sulfur metabolism to counteract the reactive oxygen species induced by rifampicin. …”
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12457
Differential expression and localization of expansins in Arabidopsis shoots: implications for cell wall dynamics and drought tolerance
Published 2025-02-01“…These findings highlight the critical role of EXPA1 in regulating plant growth, development, and stress response, with potential applications in improving drought tolerance in crops.…”
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12458
Polymorphism T3111C of the Clock gene in ethnic groups of women from Russia and Buryatia
Published 2018-04-01“…Circadian rhythms are regulated by the group of circadian genes. It is known that women suffer from sleep disorders more often than men. …”
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12459
Uptake of CCR7 by KIR2DS4+ NK Cells Is Induced upon Recognition of Certain HLA-C Alleles
Published 2015-01-01“…Here, we examined the functional outcome of the KIR2DS4/HLA class I interaction by the use of an alternative functional system based on the ability of KIR2DS4 to regulate the mechanism of trogocytosis by NK cells. …”
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12460
Naringenin inhibits lipid accumulation by activating the AMPK pathway in vivo and vitro
Published 2023-07-01“…Real-time PCR analysis results showed that naringenin regulated the expression of lipid metabolism genes. …”
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