Computational identification and experimental validation of novel Saccharum officinarum microRNAs along with their targets through RT-PCR approach by Abdul Baqi, Samiullah, Jadoon Khan, Asma Sadiq, Yousaf Khan, Shahid Ali, Syed Nadeem ul Hassan Mohani, Naqeebullah Khan, Tawaf Ali Shah, Khalid S. Almaary, Youssouf Ali Younous, Mohammed Bourhia

“…Thus, the novel sugarcane miRNAs target a wide range of important genes help regulate the environment for sugarcane to generate a higher-quality crop.…”
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Parthenolide improves sepsis-induced coagulopathy by inhibiting mitochondrial-mediated apoptosis in vascular endothelial cells through BRD4/BCL-xL pathway by Jun Zhang, Xing Zhu, Yong Li, Yinyu Wu, Yunxia Du, Hai Yang, Zhengchao Liu, Haoyu Pei, Rui Li, Huan Luo, Deyu Zuo, Han She, Qingxiang Mao

“…The role of Parthenolide (PTL) in regulating SIC by protecting VECs remains unclear. Methods The study utilized septic rats and lipopolysaccharide (LPS)-stimulated VECs to simulate a SIC model and observe the therapeutic effects of PTL. …”
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Cardiomyocyte-Restricted Deletion of PPARβ/δ in PPARα-Null Mice Causes Impaired Mitochondrial Biogenesis and Defense, but No Further Depression of Myocardial Fatty Acid Oxidation... by Jian Liu, Peiyong Wang, Lan He, Yuquan Li, Jinwen Luo, Lihong Cheng, Qianhong Qin, Lawrence A. Brako, Woo-kuen Lo, William Lewis, Qinglin Yang

“…It is well documented that PPARα and PPARβ/δ share overlapping functions in regulating myocardial lipid metabolism. However, previous studies demonstrated that cardiomyocyte-restricted PPARβ/δ deficiency in mice leads to severe cardiac pathological development, whereas global PPARα knockout shows a benign cardiac phenotype. …”
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Experimental identification of I-mode characteristics at the edge of FIRE mode in KSTAR by Chweeho Heo, SangJin Park, GyungJin Choi, Jaewook Kim, Eun-jin Kim, YoungMu Jeon, Minjun J. Choi, Hyunsun Han, Choongki Sung, TaikSoo Hahm, Yong-Su Na

“…The edge region of the recently discovered fast ion-regulated enhancement mode (FIRE mode) (Han and Park et al 2022 Nature 609 269–275), which primarily operates in the unfavorable ion $\nabla B$ drift configuration, is investigated in detail for the first time. …”
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Rapamycin Improves Palmitate-Induced ER Stress/NF κ B Pathways Associated with Stimulating Autophagy in Adipocytes by Jiajing Yin, Liping Gu, Yufan Wang, Nengguang Fan, Yuhang Ma, Yongde Peng

“…Autophagy helps to adapt to cellular stress and involves in regulating innate inflammatory response. In present study, we examined the activity of rapamycin, a mTOR kinase inhibitor, against endoplasmic reticulum stress and inflammation in adipocytes. …”
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Numerical assessment of solar panel with utilizing ferrofluid flow within wavy duct equipped with V-shaped fins by Mohammed A. Tashkandi, Ali Basem, Hussein A.Z. AL-bonsrulah, Lioua Kolsi, Mahmood Shaker Albdeiri, Lotfi Ben Said, Amira M. Hussin

“…Lorentz force is applied in the y-axis direction to regulate the flow of the ferrofluid, a mixture of water and magnetic nanoparticles. …”
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Exosomes Derived from Stem Cells from the Apical Papilla Promote Dentine-Pulp Complex Regeneration by Inducing Specific Dentinogenesis by Xueying Zhuang, Lingli Ji, Huan Jiang, Yao Liu, Xuemei Liu, Jing Bi, Weidong Zhao, Zhenjiang Ding, Xu Chen

“…Exosomes are the key regulator for the paracrine activity of stem cells and can influence the function of recipient cells. …”
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Nobiletin restores the intestinal barrier of HFD-induced obese mice by promoting MHC-II expression and lipid metabolism by Ni Yang, Yue-Shan Pang, Yali Zheng, Yan-Ju Gong, Wei-Jun Ding

“…Taken together, nobiletin restored intestinal barrier integrity and lipid metabolism by regulating MHC-II expression.…”
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The Treg/Th17 Imbalance in Patients with Obstructive Sleep Apnoea Syndrome by Jin Ye, Hui Liu, Gehua Zhang, Peng Li, Zhiyuan Wang, Shaotong Huang, Qintai Yang, Yuan Li

“…Obstructive sleep apnoea syndrome (OSAS) is a chronic inflammatory disease regulated by T lymphocytes. Our purpose is to assess the pattern of Th17 cells and CD4+CD25+Foxp3+ regulatory T (Treg) cells in peripheral blood of patients with OSAS. …”
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Dissecting the Molecular Mechanism of Wang-Bi Capsule in the Treatment of Experimental Rheumatoid Arthritis Based on Synovial Tissue Proteomic Analysis by Haiyang Shu, Yingjie Shi, Li Li, Ning Zhao, Cheng Lu, Aiping Lu, Xiaojuan He

“…Furthermore, the proteomic analysis of synovial tissue showed that WB could regulate several signaling pathways associated with inflammation or cell migration, such as “IL-1 signaling,” “IL-8 signaling,” and “CXCR4 signaling.” …”
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The Imbalance of FOXP3/GATA3 in Regulatory T Cells from the Peripheral Blood of Asthmatic Patients by Tiantian Chen, Xiaoxia Hou, Yingmeng Ni, Wei Du, Huize Han, Youchao Yu, Guochao Shi

“…Treg cells decreased in asthmatic patients, with an impaired immunosupression function and a Th2-like phenotype, which may be due to overexpression of GATA3 and FOXP3, regulated by USP21 and PIM2, respectively.…”
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Identifying the Economic Criteria for Sustainable Development Reporting Based on Islamic Texts at the Level of Companies by Morteza Yousefi, Rasoul Baradaran Hassanzadeh, Ali Reza Radbin, Mohammad Ali Rabbipoor, Saeed Hassanzadeh Delgsha

“…Findings showed that the components of the economic dimension of sustainability reporting in Islamic texts include 18 components and 268 examples. which can be effective for standardization in the field of sustainable reporting and disclosure regulations of the stock exchange and securites organization teachings and Islamic values.…”
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Comprehensive landscape and oncogenic role of extrachromosomal circular DNA in malignant biliary strictures by Zhuo Cheng, Xuanmei Luo, Wenzheng Liu, Xiaofang Lu, Hong Chang, Yingchun Wang, Wei Zheng, Xiue Yan, Yonghui Huang

“…EccDNA carrying miR-106a/363 cluster or miR-374b/421 cluster were proven to regulate cancer gene expression, accelerate tumor proliferation, and inhibit tumor apoptosis. …”
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3D Electrospun Nanofiber-Based Scaffolds: From Preparations and Properties to Tissue Regeneration Applications by Shanshan Han, Kexin Nie, Jingchao Li, Qingqing Sun, Xiaofeng Wang, Xiaomeng Li, Qian Li

“…Electrospun nanofibers have been frequently used for tissue engineering due to their morphological similarities with the extracellular matrix (ECM) and tunable chemical and physical properties for regulating cell behaviors and functions. However, most of the existing electrospun nanofibers have a closely packed two-dimensional (2D) membrane with the intrinsic shortcomings of limited cellular infiltration, restricted nutrition diffusion, and unsatisfied thickness. …”
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The intervention effects of Lactobacillus casei LC2W on Escherichia coli O157:H7 -induced mouse colitis by Guangqiang Wang, Hongyu Tang, Ying Zhang, Xiang Xiao, Yongjun Xia, Lianzhong Ai

“…Furthermore, L. casei LC2W could down-regulate the expression of pro-inflammatory cytokines (TNF-α, IL-6, and IL-1β) and protect the intestinal barrier function by improving the level of MUC2, ZO-1 and E-cadherin 1 compared to the control group. …”
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Rapid growing mass of the mandible due to an oral metastasis of thymoma: Case report of an extremely rare localization and review of published cases by Francesco Scilla, Cosimo Rupe, Gioele Gioco, Luca Raffaelli, Filippo Lococo, Ciro Mazzarella, Guido Rindi, Romeo Patini, Carlo Lajolo

“…Thymomas and thymic carcinomas are the two main tumors that can affect the thymus, a lymphatic gland that plays an important role in regulating the immune system. The aims of this paper are (i) to describe an extremely rare case of thymoma metastasis to the oral cavity (ii) report all published cases of thymic tumor metastases to the oral cavity. …”
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The mutational landscape of Staphylococcus aureus during colonisation by Francesc Coll, Beth Blane, Katherine L. Bellis, Marta Matuszewska, Toska Wonfor, Dorota Jamrozy, Michelle S. Toleman, Joan A. Geoghegan, Julian Parkhill, Ruth C. Massey, Sharon J. Peacock, Ewan M. Harrison

“…Despite limited within-host genetic diversity, we observed an excess of protein-altering mutations in metabolic genes, in regulators of quorum-sensing (agrA and agrC) and in known antibiotic targets (fusA, pbp2, dfrA and ileS). …”
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Two sexually compatible monokaryons from a heterokaryotic Lentinula edodes strain respond differently to heat stress by Yuan Guo, Wenyu Jiao, Yajie Zhang, Meiting Tan, Qi Gao, Yu Liu, Shouxian Wang

“…The differentially accumulated metabolites (DAMs) of both strains were enriched in the glycerophospholipid metabolism, alpha-linolenic acid metabolism, biosynthesis of cofactors, etc, but were regulated differently in each strain. The enriched KEGG pathways for SP3 tend to be downregulated, whereas those in SP30 exhibited a contrary trend. …”
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Regular Voluntary Exercise Potentiates Interleukin-1β and Interleukin-18 Secretion by Increasing Caspase-1 Expression in Murine Macrophages by Ken Shirato, Kazuhiko Imaizumi, Takuya Sakurai, Junetsu Ogasawara, Hideki Ohno, Takako Kizaki

“…These results indicate that the increased IL-1β and IL-18 secretion in VE mice are regulated posttranscriptionally. On the other hand, macrophages from VE mice showed higher amounts of caspase-1 protein than did cells from SC mice. …”
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CD154 Induces Interleukin-6 Secretion by Kidney Tubular Epithelial Cells under Hypoxic Conditions: Inhibition by Chloroquine by Antoine Dewitte, Julien Villeneuve, Sébastien Lepreux, Marion Bouchecareilh, Xavier Gauthereau, Claire Rigothier, Christian Combe, Alexandre Ouattara, Jean Ripoche

“…Although hypoxia is an essential constituent of the inflammatory reaction, if and how platelets and CD154 regulate inflammation in hypoxic conditions remain unclear. …”
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