Hypoxia impairs decitabine-induced expression of HLA-DR in acute myeloid leukaemia cell lines by Sam Humphries, Sean M. Burnard, Courtney D. Eggins, Simon Keely, Danielle R. Bond, Heather J. Lee

“…Transcriptional responses to HMA treatment were also altered, with HMAs failing to up-regulate antigen presentation pathways in hypoxia. …”
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Cardamom extract alleviates tamoxifen-induced liver damage by suppressing inflammation and pyroptosis pathway by Wedad S. Sarawi, Hala A. Attia, Afraa Alzoubi, Nour Alanazi, Raeesa Mohammad, Rehab A. Ali

“…In conclusion, CRDE demonstrated the potential to protect the liver from TAM-induced damage by regulating mechanisms involving oxidative damage, inflammation, and pyroptosis.…”
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RNA Sequencing Reveals the Differentially Expressed circRNAs between Stable and Unstable Carotid Atherosclerotic Plaques by Xueguang Lin, Ying Deng, Lujuan Ye, Bo Chen, Jindong Tong, Weijun Shi, Bo Wang, Bo Yu, Jingdong Tang

“…Hsa-circ-0001523, hsa-circ-0008950, hsa-circ-0000571, hsa-circ-0001946, and hsa-circ-0000745 may be involved in regulating the stability of atherosclerotic plaques and serves as a therapeutic target for unstable plaques.…”
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Patient Perspectives on Health Data Privacy and Management: “Where Is My Data and Whose Is It?” by Mart Wetzels, Eva Broers, Peter Peters, Loe Feijs, Jos Widdershoven, Mirela Habibovic

“…The focus groups were conducted using a semistructured protocol which was organized around three themes: privacy regulations, data storage, and transparency and privacy management. …”
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The Role of the Commercial Space Industry within the US National Security under the Trump Administration by E. A. Kuznetsov

“…The Trump’s administration has contributed to the development of the industry through liberalization of regulations and involvement of private sector in the new large-scale projects, such as the Artemis program. …”
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The Japanese encephalitis virus NS1' protein facilitates virus infection in mosquitoes. by Yuwei Liu, Yutian Huang, Ruidong Li, Chang Miao, Yi He, Changhao Xu, Xi Zhu, Bowen Li, Rui Wu, Qin Zhao, Yiping Wen, Xiaobo Huang, Qi-Gui Yan, Yi-Fei Lang, Shan Zhao, Yiping Wang, Yajie Hu, San-Jie Cao, Senyan Du

“…Specifically, the NS1' protein was found to facilitate infection through the suppression of antimicrobial peptides (AMPs) regulated by the Toll pathway.<h4>Conclusions/significance</h4>Our research demonstrated that the JEV NS1' protein contributes to immune escape, thereby enhancing viral infection in mosquitoes. …”
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In vitro micropropagation protocols for two endangered Dianthus species - via in vitro culture for conservation and recultivation purposes by Dóra Farkas, Judit Csabai, Angéla Kolesnyk, Pál Szarvas, Judit Dobránszki

“…The shoot clusters were subsequently transferred onto elongation medium (plant growth regulator-free MS medium) for 3 weeks. Individual shoots separated from the shoot clusters were cultured on MS medium supplemented with 0.54 µM NAA and 2% sucrose for 3 weeks for rooting. …”
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Myeloma cell-derived CXCL7 facilitates proliferation of tumor cells and occurrence of osteolytic lesions through JAK/STAT3 pathway by Yue Wang, Tianwei Lan, Qiongyan Zhang, Chi Zhou, Peng Liu

“…CXCL7 might be a crucial regulator of osteolytic damage in MM. Subsequently, the association between the expression level of CXCL7 and pathological fractures in patients was investigated, and the impact of CXCL7 on MM proliferation was confirmed both in vivo and in vitro. …”
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A minimal mathematical model for the initial molecular interactions of death receptor signalling by Christian Winkel, Simon Neumann, Christina Surulescu, Peter Scheurich

“…TNF itself is a strong proinflammatory regulator of the innate immune system, but has been also recognized as a major factor in progression of autoimmune diseases. …”
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Beyond nutritional immunity: immune-stressing challenges basic paradigms of immunometabolism and immunology by Edmund K. LeGrand

“…At present much of the field of immunometabolism centers on how nutrition and metabolism regulate immune function, a central feature being the inefficient use of glucose via aerobic glycolysis (with much lactate/lactic acid production) by effector immune cells. …”
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Public Perception of Genetically Modified Organisms and the Implementation of Biosafety Measures in Kenya by Kunyanga Nkirote Catherine, B. Roy Mugiira, N. Josephat Muchiri

“…The findings are important in addressing gaps in the current GMO regulations and implementation aimed at increasing awareness of GMO technology as well as informing policy on biotechnology.…”
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Von unten und von oben? . Hugo Riemanns reflexive Theorie in der Moderne by Hermann Danuser

“…Against the background of its self-reflective aspects, its regulative and cartographic approach, and its systematic outlook, Riemann’s theory carries signs of modernity. …”
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Legal Principles of Procedural Activity and Interaction of Employees of Operative Divisions at Execution of Instructions of Interrogators, Investigators, Prosecutors in Regard to C... by O. O. Yukhno

“…The author of the article provides a retrospective analysis of the provisions of legislative acts of Ukraine, decisions of the Constitutional Court of Ukraine and the European Court of Human Rights, as well as some national criminal procedural legislation and departmental regulations on legal grounds for procedural activities and interaction of operative units to execute written instructions of interrogators, investigators, prosecutors on investigative (search) actions and secret investigative (search) actions. …”
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The Effect of Chronic Candesartan Therapy on the Metabolic Profile and Renal Tissue Cytokine Levels in the Obese Zucker Rat by Carolyn M. Ecelbarger, Arjun Rash, Rajesh K. Sinha, Swasti Tiwari

“…Furthermore, candesartan increased growth-regulated oncogene, transforming growth factor-β1 and IL-18 in OZ kidneys to a level higher than LZ or untreated OZ. …”
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Investigative (search) and covert investigative (search) actions as means of proof in criminal proceedings related to illegal trafficking in firearms or ammunition by S. V. Kozachenko

“…This study is aimed at creating preconditions for improving existing and developing new forensic recommendations and methods for investigating criminal proceedings related to illegal trafficking in firearms or ammunition, as well as developing proposals for improving the current criminal procedure legislation in terms of regulating evidence. As a result of the study, it has been obtained new scientifically substantiated results which contribute to improving the provision of investigative bodies with modern methodological recommendations aimed at increasing the efficiency of investigation of criminal offenses related to illegal trafficking in firearms or ammunition. …”
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Cell adhesion molecules involved in the leukocyte recruitment induced by venom of the snake Bothrops jararaca by Stella R. Zamuner, Catarina F. P. Teixeira

“…This is the first in vivo evidence that snake venom is able to up-regulate the expression of adhesion molecules by both leukocytes and endothelial cells. …”
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Association of disease activity with programmed cell death 1 and its ligand programmed cell death ligand 1 expressions in lupus patients by Eman Eissa, Rania Kandil, Nehal El-Ghobashy, Walaa Abdelfattah, Zainab Hammouda, Sara Medhat Gadelsayed, Faten Bayoumi

“…Conclusion: PD-1 and its ligand PD-L1 could have a role as regulators for immune activation in patients with SLE.…”
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Objectives of military personnel financial and legal protection under martial law by Yu. M. Kret

“…To conclude, we note that budget expenditures for the social sphere in general and for the financing of special social rights of military personnel in particular, as well as for other categories of citizens, need to be regulated at the stages of drafting, reviewing and adopting the budget law. …”
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Mesenchymal Stem Cells from Human Exfoliated Deciduous Teeth and the Orbicularis Oris Muscle: How Do They Behave When Exposed to a Proinflammatory Stimulus? by Alessander Leyendecker Junior, Carla Cristina Gomes Pinheiro, Daniela Yukie Sakai Tanikawa, José Ricardo Muniz Ferreira, Mariane Tami Amano, Daniela Franco Bueno

“…Mesenchymal stem cells (MSCs) have been studied as a promising type of stem cell for use in cell therapies because of their ability to regulate the immune response. Although they are classically isolated from the bone marrow, many studies have sought to isolate MSCs from noninvasive sources. …”
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Pressure Modification or Barrier Issues during Polymer Flooding Enhanced Oil Recovery by Wang Dongmei, Shane Namie, Randall Seright

“…The maximum allowable injection pressure is commonly constrained by caprock integrity, injection equipment, and/or regulations, even though fractures can be beneficial to polymer injectivity. …”
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