Common variants in left/right asymmetry genes and pathways are associated with relative hand skill. by William M Brandler, Andrew P Morris, David M Evans, Thomas S Scerri, John P Kemp, Nicholas J Timpson, Beate St Pourcain, George Davey Smith, Susan M Ring, John Stein, Anthony P Monaco, Joel B Talcott, Simon E Fisher, Caleb Webber, Silvia Paracchini

“…As PCSK6 is known to regulate NODAL in the development of left/right (LR) asymmetry in mice, we developed a novel approach to GWAS pathway analysis, using gene-set enrichment to test for an over-representation of highly associated variants within the orthologs of genes whose disruption in mice yields LR asymmetry phenotypes. …”
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Beneficial effects of AOS-iron supplementation on intestinal structure and microbiota in IDA rats by Hong He, Hui Teng, Qun Huang, Dan He, Fengping An, Lei Chen, Hongbo Song

“…These findings indicated that AOS-iron effectively repaired the damaged intestinal tissue and ameliorated iron metabolic disorders by regulating gut microbiota desirably, which could provide references for the treatment of IDA.…”
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The Anti-Inflammatory Cytokine, Interleukin-10, Inhibits Inflammatory Mediators in Human Epithelial Cells and Mouse Macrophages Exposed to Live and UV-Inactivated Chlamydia trachom... by Abebayehu N. Yilma, Shree R. Singh, Stacie J. Fairley, Murtada A. Taha, Vida A. Dennis

“…Our data imply that IL-10 is an important regulator of the initial inflammatory response to C. trachomatis infection and that further investigations be made into IL-10 use to combat inflammation induced by this bacterium.…”
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Dopamine and 24-Epibrassinolide Upregulate Root Resilience, Mitigating Lead Stress on Leaf Tissue and Stomatal Performance in Tomato Plants by Lohana Ribeiro Prestes, Madson Mateus Santos da Silva, Sharon Graziela Alves da Silva, Maria Andressa Fernandes Gonçalves, Bruno Lemos Batista, Ivan Becari Viana, Allan Klynger da Silva Lobato

“…For roots, both plant growth regulators maximized the epidermis, with increases in treatments Pb²⁺ − DOP + EBR (45%), Pb²⁺ + DOP − EBR (24%), and Pb²⁺ + DOP + EBR (36%), when compared with equal treatment without Pb²⁺. …”
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Dual functional hydrogel of osteoclastic-inhibition and osteogenic-stimulation for osteoporotic bone defect regeneration by Lei Yu, Wentao Wang, Chang Lv, Qian Chen, Peng Yang, Zhenrong Qi, Haomiao Yu, Ruiqi Cao, Wenhao Li, Yi Qin, Gaoran Ge, Peilai Liu, Lixin Zhu, Houyi Sun, Dechun Geng, Liang Zhang

“…This dual-action system synergistically regulates osteoblast and osteoclast activity, optimizing the pathological microenvironment of osteoporosis and facilitating the repair of osteoporotic bone defects. …”
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The Effect of long-term rapamycin administration on intracellular calcium quantification and RhoA activity in kainic acid epilepsy model by Machlusil Husna, Kusworini Handono, Hidayat Sujuti, Aulanni’am Aulanni’am, Rumman Karimah, Afiyfah Kiysa Waafi, Alya Satira

“…RhoA signaling pathway is regulated through the mTORC2 pathway; thus we hypothesized that long-term exposure to rapamycin could inhibit intracellular Ca2+ and RhoA activity as one of the mTORC2 downstream proteins, in a temporal lobe epilepsy model. …”
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INFLUENCING FACTORS ON COSTS AND DECISION MAKING . A LOOK AT THE BAKERY INDUSTRY by Florina LUP, Carmen SCORTE, Daniela ZAPODEANU

“…The paper is an empirical, quantitative research, based on the analysis of cost information, analysis of cost changes and the impact of factors that we consider to be determinants: the cost of purchasing raw materials under the influence of inflation, circular economy principles and other pedoclimatic or geopolitical factors, the cost of labour under the influence of legal regulations, the cost of energy under the influence of inflation, the energy crisis, geopolitical factors. …”
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Multidimensional Analysis of PANoptosis-Related Molecule CASP8: Prognostic Significance, Immune Microenvironment Effect, and Therapeutic Implications in Hepatocellular Carcinoma by Fei Peng, Fang Zhu, Baodi Cao, Liang Peng

“…In addition, CASP8 was found to regulate YEATS2 in HCC, highlighting a potential pathway in tumor progression. …”
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The place of the State Bureau of Investigation in the system of state law enforcement agencies of Ukraine by M. M. Makarenko

“…It is noted that state bodies (public authorities) are characterised by their own specific features, among which the following are distinguished: a set of state bodies form the apparatus of the State, and therefore each of them is one of the elements of the integral system of the State apparatus; they are created and operate on the basis of relevant regulations, in the person of one person (citizen) or a group of citizens; each structural unit (state body) is endowed with unique powers of state power; they are created with the aim of performing tasks and It is also emphasised that the State Bureau of Investigation is a law enforcement agency. …”
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Legal protection of community members in the Complete Systematic Land Registration Program by I. Z. Rusmanira, . Sudarsono, M. H. Masykur

“…This decision opens up opportunities for local governments to adopt additional regulations related to the financing of PTSL, which is often a loophole for illegal extortion. …”
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Privacy policy compliance detection and analysis based on knowledge graph by ZHANG Xiheng, LI Xin, TANG Peng, HUANG Ruiqi, HE Yuan, QIU Weidong

“…It established clear regulations for personal information controllers in their activities involving the collecting, storing, using, and sharing of personal information. …”
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Legal liability of servicemen for improper performance of duties during physical fitness testing by S. M. Ivashchenko, S. V. Hashenko, P. M. Ponomarenko

“…The study includes an analysis of most of the national legislation that regulates the issue of legal liability of military personnel for improper performance of official duties during physical fitness testing. …”
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A Qualitative Study on the Tax Amnesty Perception of Income Taxpayers: The Case of Türkiye by Serap Püren

“…Tax amnesty, which is not regulated in the Tax Procedure Law, has been implemented from time to time since 1924. …”
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Legal principles of international cooperation of the National Police of Ukraine with foreign law enforcement agencies by V. V. Pylyp

“…Therefore, based on a synthesis of theoretical developments of scholars in the context of studying the issues related to international cooperation between the National Police of Ukraine and other States, and an analysis of the provisions of the legal acts regulating the activities and procedure for interaction between the National Police and bodies, institutions and organisations of other countries, this article defines the legal framework for interaction between these entities. …”
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Creating a model of threats to Ukraine’s national critical infrastructure as a basis for ensuring its security and resilience by D. S. Melnyk

“…The perspective measures that will contribute to both the stable functioning of critical infrastructure facilities and ensure their proper protection are outlined: enshrining in Ukrainian legislation the need to develop a model of threats to critical infrastructure, adopting regulations on standardisation of risk management processes for critical infrastructure in order to prevent threats, and more.…”
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Dimensions of Rational Decision-Making during the Demographic Transition; Aranjuez (Spain) Revisited by David Reher, Glenn Sandström

“…The results offer convincing proof that couples were continually regulating their fertility in order to achieve reproductive goals both in terms of net fertility and of the sex composition of the resulting sibset. …”
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Factors affecting the adoption of RFID in the food supply chain: a systematic literature review by Fundiswa Masekwana, Osden Jokonya

“…The results indicate that technological (complexity, cost, and security), organizational (technical skill and management support), and environmental (maintenance and support, IT policies and regulations) are the major factors that affect the adoption of RFID in the sustainable food system industry. …”
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THE ROLE OF PRIMARY GLOBAL PUBLIC GOODS IN INFORMATION SOCIETY by L. N. Shcerbakova

“…Their manufacture should be planned by the world regulating centre. The role of global public blessings as tools of development and growth of new economy is defined. …”
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Hsa_circ_0000190 Promotes NSCLC Cell Resistance to Cisplatin via the Modulation of the miR-1253/IL-6 Axis by Hua He, Tian Li

“…IL-6 was identified as a major miR-1253 target in this context, with miR-1253 regulating chemoresistance in NSCLC cells in part by preventing IL-6 upregulation. …”
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Communication competence in the activities of law enforcement institutions by Augustė Taraskevičiūtė, Rasa Dobržinskienė

“…Communication is legally regulated by codes of ethics, public relations legislation, and professional standards. …”
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