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11701
Metabolomics and gene expression levels reveal the positive effects of teaseed oil on lifespan and aging process in Caenorhabditis elegans
Published 2023-07-01“…In general, this paper claimed that TO could prolong lifespan and slow down aging process via regulating the lipids, amino acids and carbohydrates metabolism.…”
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11702
Identification of Aberrantly Expressed miRNAs in Gastric Cancer
Published 2014-01-01“…Gene ontology analysis revealed that those dysregulated miRNAs mainly take part in regulating cell proliferation. The levels of has-miR-105, -213*, -514b, and -548n were tested by real-time PCR and have high levels in cancerous tissues. …”
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11703
Mycobiology of Dental Unit Water: A Systematic Scoping Review
Published 2025-02-01“…Finally, it was notable that there are currently no specific regulations by any dental authority on permissible levels of fungi, as opposed to bacteria, in DUWLs. …”
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11704
Genome wide association studies on seven yield‐related traits of 183 rice varieties in Bangladesh
Published 2024-06-01“…Abstract Rice genetic diversity is regulated by multiple genes and is largely dependent on various environmental factors. …”
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11705
Enhancing soil quality in soybean cultivation: Mycorrhizal technology combined with intercropping under high cadmium stress
Published 2025-01-01“…The combined treatment also enhanced soil enzyme activity by regulating the relative abundance of dominant or key genera such as Subgroup_6, Rokubacteriales and Pseudarthrobacter. …”
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11706
Sympathetic innervation induced by nerve growth factor promotes malignant transformation in gastric cancer
Published 2025-01-01“…Abstract Sympathetic nerves regulate nearly all human organs. Their peripheral nerves are present in tumor tissue. …”
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11707
Niacin Inhibits Vascular Inflammation via Downregulating Nuclear Transcription Factor-κB Signaling Pathway
Published 2014-01-01“…The study aimed to investigate the effect of niacin on vascular inflammatory lesions in vivo and in vitro as well as its lipid-regulating mechanism. In vivo study revealed that niacin downregulated the levels of inflammatory factors (IL-6 and TNF-α) in plasma, suppressed protein expression of CD68 and NF-κB p65 in arterial wall, and attenuated oxidative stress in guinea pigs that have been fed high fat diet. …”
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11708
Neural Network-Based Lower Limb Prostheses Control Using Super Twisting Sliding Mode Control
Published 2025-01-01“…The ST-SMC controller regulates the motion of the prosthetic joints according to specified reference trajectories. …”
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11709
Pilocarpine-Induced Status Epilepticus Is Associated with Changes in the Actin-Modulating Protein Synaptopodin and Alterations in Long-Term Potentiation in the Mouse Hippocampus
Published 2017-01-01“…Here, we addressed the question of whether pilocarpine-induced status epilepticus affects synaptopodin (SP), an actin-binding protein, which regulates the ability of neurons to express synaptic plasticity. …”
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11710
Effect of the addition of Sc element on the microstructure and properties of Al80Li5Mg5Zn5Cu5 high-entropy alloy
Published 2025-01-01“…To achieve better performance of the Al₈₀Li₅Mg₅Zn₅Cu₄Sc₁ high-entropy alloy, the distribution and size of the precipitate phase and matrix phase were regulated through heat treatment. It was found that after holding at 400 °C for 1 h, the room temperature tensile and compressive strengths of the Sc-containing HEA increased by 68.8% and 63.4%, respectively, compared to the as-cast structure. …”
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11711
Comprehensive RNA-seq analysis of benign prostatic hyperplasia (BPH) in rats exposed to testosterone and estradiol
Published 2025-01-01“…The DEGs were mainly involved in mitotic nuclear division, nuclear chromosome segregation, and cytokine cell receptor interactions. DEGs were also regulated by 250 miRNAs. In conclusion, we built a novel T + E2-induced rat BPH model, and discovered potentially important genes, pathways, and miRNA-mRNA regulatory networks.…”
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11712
Review of osteokines in spinal cord injury: potential biomarkers during rehabilitation
Published 2025-01-01“…Osteokines, secreted from bone tissue, could play multiple roles in regulating bone density, muscle mass, glucose metabolism, and functions of the central nervous system-changes in the osteokine levels after SCI have been detected. …”
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11713
Exclusive Cutaneous and Subcutaneous Sarcoidal Granulomatous Inflammation due to Immune Checkpoint Inhibitors: Report of Two Cases with Unusual Manifestations and Review of the Lit...
Published 2019-01-01“…The primary target antigens are cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4), a downregulator of T-cell activation, and programmed cell death-1 receptor (PD-1), a regulator of T-cell proliferation. This enhanced immune response can induce autoimmune adverse effects in many organs. …”
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11714
Evolution of Alzheimer’s Disease Therapeutics: From Conventional Drugs to Medicinal Plants, Immunotherapy, Microbiotherapy and Nanotherapy
Published 2025-01-01“…Furthermore, the therapeutic potential of emerging approaches, such as the use of microRNAs to regulate key cellular processes and nanotherapy, which enables precise drug delivery to the central nervous system, is analyzed. …”
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11715
Single-cell transcriptomics reveals novel chondrocyte and osteoblast subtypes and their role in knee osteoarthritis pathogenesis
Published 2025-02-01“…Sparc + osteoblasts have negatively regulated bone mineralization and osteoblastic differentiation, aggravated the pathological remodeling of subchondral bone, and promoted the progression of KOA. …”
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11716
PEBP1 amplifies mitochondrial dysfunction-induced integrated stress response
Published 2025-01-01“…Consistently, overexpression of PEBP1 potentiated ISR activation by heme-regulated inhibitor (HRI) kinase, the principal eIF2α kinase in the mitochondrial ISR pathway. …”
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11717
Safety and efficacy of long-term nicotinamide mononucleotide supplementation on metabolism, sleep, and nicotinamide adenine dinucleotide biosynthesis in healthy, middle-aged Japane...
Published 2024-02-01“…Accumulating evidence from both rodents and humans suggests that the levels of nicotinamide adenine dinucleotide (NAD+), a regulator of many biological processes, declines in multiple organs and tissues with aging and obesity. …”
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11718
The Impact of Bioactive Lipids on Cardiovascular Development
Published 2011-01-01“…Both LPA and S1P positively regulate the proliferative capacity of murine ES cells. …”
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11719
Glycogen Synthase Kinase 3β Promotes Postoperative Cognitive Dysfunction by Inducing the M1 Polarization and Migration of Microglia
Published 2020-01-01“…The role of GSK-3β in regulating innate immune activation has been well documented, but as far as we know, its role in POCD has not been fully elucidated. …”
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11720
Manipulation of seed coat content for increasing oil content via modulating BnaMYB52 in Brassica napus
Published 2025-02-01“…Thus, our findings identify the molecular mechanism of MYB52-BAN/PMEI14 modules regulating SCC and SOC and provide a potential target for oil content improvement in B. napus.…”
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