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11661
Comprehensive assessment of a miRNA-mRNA regulatory network in Meretrix meretrix: Implications for metabolism and autophagy across divergent growth rates
Published 2025-03-01“…Characterized by their dynamic expression patterns, miRNAs play a crucial role in regulating a multitude of biological processes, including metabolism and autophagy. …”
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11662
Gene expression of psychiatric disorder-related kinesin superfamily proteins (Kifs) is potentiated in alternatively activated primary cultured microglia
Published 2025-01-01“…Although cellular analyses based on cultured microglia have been conducted, the molecular mechanism regulating microglial polarization remains elusive. …”
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11663
The influence of foreign, busy board members, and gender diversity on firm bankruptcy
Published 2025-12-01“…The findings inform Saudi regulators on enhancing corporate governance and board effectiveness to support the structure of finances in Saudi firms. …”
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11664
Torsional Behavior of High-Strength Concrete Beams with Minimum Reinforcement Ratio
Published 2019-01-01“…Taking into account that this also concerns the design for torsion, this study intends to investigate the regulations related to the torsional minimum reinforcement ratio in view of the minimum ductility requirement with focus on Eurocode 2. …”
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11665
Consumer Protection of Girls from Cybercrime in a Gender Perspective
Published 2024-12-01“…Education on cybersecurity should start early, with a special focus on girls. Strict regulations and policies are needed to protect girls from sexual exploitation and other cybercrimes. …”
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11666
Adeno-associated virus mediated artificial circular RNA for triggering cancer immunotherapy to treat prostate cancer
Published 2025-01-01“…IntroductionSpecifically regulating endogenous molecules is a potential molecular therapeutic strategy. …”
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11667
Impact of resistant starch formation in chickpea products on blood glucose and lipid profiles: Effects of cooking and storage conditions
Published 2025-03-01“…In humans, the boiled chickpea held at T3 has shown greater efficacy in regulating blood glucose and lipid profiles. In rats, consumption of pressure-cooked chickpea held at T3 resulted in a reduction in blood glucose level, cholesterol, triglycerides, and LDL. …”
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11668
Involvement of the TGF-β pathway in epithelialmesenchymal transition promoted by the pulmonary microenvironment in Mycoplasma pneumoniae pneumonia
Published 2024-01-01“…We explored the role of the pulmonary microenvironment in regulating epithelial-mesenchymal transition (EMT) in MPP patients with atelectasis. …”
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11669
A New Attack Recovery Approach and <italic>H</italic>∞ Performance Analysis for LFC Systems With FDI Attacks and Uncertainties
Published 2025-01-01“…Then, the recovered attacks can be used to regulate the control input signals of LFC systems to mitigate the impact of FDI attacks. …”
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11670
CRISPR/cas9 Allows for the Quick Improvement of Tomato Firmness Breeding
Published 2024-12-01“…In this study, we used a CRISPR/Cas9 system to simultaneously knock out two genes, <i>FIS1</i> and <i>PL</i>, which negatively regulate firmness in tomato. We generated single and double gene knockout mutants utilizing the tomato genetic transformation system. …”
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11671
Gut Microbiota at the Crossroad of Hepatic Oxidative Stress and MASLD
Published 2025-01-01“…Gut microbiota plays a substantial role in modulating hepatic oxidative stress through multiple pathways: impairing the intestinal barrier, which results in bacterial translocation and chronic hepatic inflammation; modifying bile acid structure, which impacts signaling cascades involved in lipidic metabolism; influencing hepatocytes’ ferroptosis, a form of programmed cell death; regulating trimethylamine N-oxide (TMAO) metabolism; and activating platelet function, both recently identified as pathogenetic factors in MASH progression. …”
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11672
Forming ability of the WC-based ceramic metal composites with different Fe-based binders by unique laser beam modulation
Published 2025-04-01“…As a result of optimizing the laser beam with variations in laser power peaks (48, 60, and 72 Watt) and constant exposure times for each laser beam profile, the melt pool temperature was regulated, primary cracks in the parts were reduced and this resulted in the fabrication of the parts with reduced process defects such as internal thermal cracks. …”
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11673
Assessing environmental and human health risks of pharmaceutical contamination in surface water
Published 2024-12-01“…This study supports ongoing efforts to monitor and regulate drug contamination in water sources, evaluating potential risks to human health and emphasizing the importance of addressing these contaminants to protect environmental and public health.…”
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11674
Differential Fasting Plasma Glucose and Ketone Body Levels in GHRKO versus 3xTg-AD Mice: A Potential Contributor to Aging-Related Cognitive Status?
Published 2017-01-01“…Since the majority of brain nutrients come from the periphery, this study examined whether the capacity to regulate peripheral glucose levels and KB production differs in animals with successful cognitive aging (growth hormone receptor knockouts, GHRKOs) versus unsuccessful cognitive aging (the 3xTg-AD mouse model of Alzheimer’s disease). …”
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11675
Iron Reduces M1 Macrophage Polarization in RAW264.7 Macrophages Associated with Inhibition of STAT1
Published 2017-01-01“…The molecular signature of M1 macrophages showed high levels of iron storage (ferritin), a low level of iron export (ferroportin), and changes of iron regulators (hepcidin and transferrin receptors), which favour iron sequestration in the reticuloendothelial system and are benefit for inflammatory disorders. …”
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11676
MAGI2-AS3 hypermethylated in promoter region promotes migration and invasion of head and neck squamous cell carcinoma via miRNA-31-5p/AR axis
Published 2025-02-01“…The effect of MAGI2-AS3 on HNSCC progression was verified in nude mice in vivo.The low expression of MAGI2-AS3 in HNSCC was caused by hypermethylation of MAGI2-AS3, which could regulate the target of miR-31-5p by sponge adsorption of miR-31-5p, and miR-31-5p could inhibit the expression of AR by directly targeting AR. …”
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11677
The Unbalanced Control Research of Fractional-Order Cascaded H-Bridge Multilevel STATCOM
Published 2025-01-01“…At the end of this paper, the results of digital simulations verify the FCHM-STATCOM complete control system’s capacity to regulate its negative-sequence currents and balance its arm operation to deal with unbalanced operative situations. …”
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11678
Inheritance of yield and fiber length in hybrids cotton of the first generation F1
Published 2025-01-01“…Therefore, it can be argued that the fiber length in F1 hybrids is mainly regulated by dominant genes.…”
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11679
Variational graph autoencoder for reconstructed transcriptomic data associated with NLRP3 mediated pyroptosis in periodontitis
Published 2025-01-01“…Abstract The NLRP3 inflammasome, regulated by TLR4, plays a pivotal role in periodontitis by mediating inflammatory cytokine release and bone loss induced by Porphyromonas gingivalis. …”
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11680
The Stability of a Model Substrate for Topoisomerase 1-Mediated DNA Religation Depends on the Presence of Mismatched Base Pairs
Published 2011-01-01“…Topoisomerase 1 (Top1) enzymes regulate DNA superhelicity by forming covalent cleavage complexes that undergo controlled rotation. …”
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