Environmental health risks and impacts of PM2.5 exposure on human health in residential areas, Bantul, Yogyakarta, Indonesia by Azham Umar Abidin, Anisful Lailil Munawaroh, Aulia Rosinta, Arvi Tri Sulistiyani, Iwan Ardianta, Fajri Mulya Iresha

“…The findings emphasize the imperative for more rigorous air quality standards and regulations, enhanced public awareness and education regarding preventive practices, and urban planning development strategies incorporating green infrastructure. …”
Get full text

Non-discrimination and equality in healthcare: guarantees of implementation in international law and Ukrainian legislation by Blashchuk T.

“…The study was conducted through a comprehensive analysis of international and national legal acts regulating non-discrimination in healthcare.The following were used methods of scientific cognition, such as terminological, logical and semantic, comparative and legal, systemic and structural, and analytical. …”
Get full text

The crosstalk between senescence, tumor, and immunity: molecular mechanism and therapeutic opportunities by Zehua Wang, Chen Chen, Jiaoyu Ai, Yaping Gao, Lei Wang, Shurui Xia, Yongxu Jia, Yanru Qin

“…Understanding how senescence regulates antitumor immunity, along with new therapeutic interventions, is essential for managing tumor cell senescence and remodeling the immune microenvironment.…”
Get full text

Synergistic effects of alginate oligosaccharide and cyanidin-3-O-glucoside on the amelioration of intestinal barrier function in mice by Jie Li, Yuanjie Guo, Liyuan Ma, Yixiang Liu, Chao Zou, Huiying Kuang, Bing Han, Yingliang Xiao, Yanbo Wang

“…The results show that, in comparison to their individual applications, the combination of AOS and C3G (mass ratio, 3:1) displayed a stronger ability to up-regulate the expression of tight junction proteins, while enhanced intestinal epithelial barrier was also observed and levels of mucin-2 and β-defensins were simultaneously increased in the intestinal mucus. …”
Get full text

NMDA Receptor Subunits Change after Synaptic Plasticity Induction and Learning and Memory Acquisition by María Verónica Baez, Magalí Cecilia Cercato, Diana Alicia Jerusalinsky

“…In CNS structures involved in cognitive functions as the hippocampus and prefrontal cortex, GluN2A and GluN2B are major regulatory subunits; their expression is dynamic and tightly regulated, but little is known about specific changes after plasticity induction or memory acquisition. …”
Get full text

Nonlinear Seismic Performance Evaluation of Flexural Slotted Connection Using Endurance Time Method by Seyed Mohamad Seyed Kolbadi, Hosein Piri, Ali Keyhani, S.Mahdi Seyed-Kolbadi, Masoud Mirtaheri

“…The equivalent statistical methods, spectral analysis, and time history analysis are usually offered in the steel structure design regulations. Among these methods, the third one is more accurate; however, it requires more time to align the accelerometers due to a large number of analyses. …”
Get full text

Exploration of the mechanism of fermented turmeric preventing glucolipid metabolic disorder: Insights into signaling of microbiota-SCFAs-brown adipose tissue axis in mice by Xingliang Xiang, Yukun Liu, Zhaoxiang Zeng, Xueyan Zhao, Qingxin Shi, Xing Huang, Haijun Yang, Chengwu Song, Shunqing Xu, Shuna Jin

“…As a result, butanoate metabolism signaling pathway was highlighted with regulating ACSM3 and HADH. Considering the poor absorption of curcuminoids, intestinal environment was analyzed for further exploring the upstream signal of short-chain fatty acids (SCFAs) metabolism. …”
Get full text

Tailoring IPM plans to fight a cloaked pest: helping smallholder farmers combat the sweetpotato weevil in sub-Saharan Africa by Chad A. Keyser, Frederick S. Walters, Haley Turner, Elka Armstrong, Jeff Davis, Brooke Bissinger, Brant Johnson, Agnes Alajo, Paul Musana, Joseph Odongo, Benard Yada, Milton A. Otema

“…Commercial growers in many developed countries rely on frequent chemical treatments and strict quarantine regulations to control SPW, however, this approach is currently not practical for many areas of SSA. …”
Get full text

Liver macrophage-derived exosomal miRNA-342-3p promotes liver fibrosis by inhibiting HPCAL1 in stellate cells by Wenshuai Li, Lirong Chen, Qi Zhou, Tiansheng Huang, Wanwei Zheng, Feifei Luo, Zhong Guang Luo, Jun Zhang, Jie Liu

“…HPCAL1, which is a fibrogenesis suppressor, could inhibit TGF-β signaling in HSCs by regulating the ubiquitination of Smad2 through direct interactions with its EF-hand 4 domain. …”
Get full text

Characteristics of transcriptome and chromatin accessibility in the peripheral blood after acute hypoxia exposure by Kuo Zeng, Pei-ru Yuan, Jin-feng Xuan, Lai-xi Zhao, Xiao-na Li, Jun Yao, Dong Zhao

“…Abstract Background Human responses and acclimation to the environmental stresses of high altitude and low oxygen are multifaceted and regulated by multiple genes. However, the mechanism of how the body adjusts in a low-oxygen environment is not yet clear. …”
Get full text

Ethyl Lactate Ameliorates Hepatic Steatosis and Acute‐on‐Chronic Liver Injury in Alcohol‐Associated Liver Disease by Inducing Fibroblast Growth Factor 21 by Yang Jiang, Shuang Wei, Shiming Shen, Yuxiao Liu, Weitong Su, Dong Ding, Zengpeng Zheng, Haokai Yu, Tingting Zhang, Qiuli Yang, Jiuxiang Zhao, Yi Shen, Xia Fang, Liangcai Lin, Dongguang Xiao, Aoyuan Cui, Qin Wan, Yadong Zhang, Yu Li, Cuiying Zhang

“…Moreover, little is known about whether and how nonethanol ingredients in alcoholic beverages regulate the pathogenesis of ALD. Here the discovery of a small molecule that activates the production and secretion of fibroblast growth factor 21 (FGF21) is reported. …”
Get full text

Rapid Enzymatic Method for Pectin Methyl Esters Determination by Lucyna Łękawska-Andrinopoulou, Efstathios G. Vasiliou, Dimitrios G. Georgakopoulos, Constantinos P. Yialouris, Constantinos A. Georgiou

“…The analyzer is fully regulated by a lab written LabVIEW program. The detection limit was 1.47 mM with an analysis rate of 7 samples h−1. …”
Get full text

GB18-06, a nanobody targeting GDF15, effectively alleviates weight loss and restores physical function in cachexia models by Yu Huang, Jinyong Wang, Xiling Wei, Hui Zhang, Wei Shang, Xiangling Zhang, Lanjiao Zhai, Xi Chen, Huiming Li, Suofu Qin

“…Growth differentiation factor 15 (GDF15) can suppress appetite and regulate energy balance through binding to glial cell-derived neurotrophic factor receptor alpha-like (GFRAL). …”
Get full text

Puerarin Suppress Apoptosis of Human Osteoblasts via ERK Signaling Pathway by Ling-juan Liu, Li-qun Liu, Tao Bo, Shi-jun Li, Zhen Zhu, Rong-rong Cui, Ding-an Mao

“…Previous studies have demonstrated that puerarin could regulate osteoblast proliferation and differentiation to promote bone formation. …”
Get full text

Effects of phosvitin phosphopeptide-Ca complex prepared by efficient enzymatic hydrolysis on calcium absorption and bone deposition of mice by Mengdie Zhao, Dong Uk Ahn, Songming Li, Wei Liu, Shengwei Yi, Xi Huang

“…The serum calcium content was the highest with the HTMP-Enz-PPP-Ca treatment (2.19 mmol/L), and it significantly down-regulated the abnormal elevation of serum alkaline phosphatase (AKP) caused by calcium deficiency. …”
Get full text

Unraveling the levels of emerging contaminants along the eastern Mediterranean Sea by Fatima Haydous, Bilal Nehmeh, Joseph Rebehmed, Josephine Al-Alam, Christopher Saab, Sara Sabbagh, Ali Hamieh, Ali Yassin, Mahmoud Wazne, Elias Akoury

“…These findings highlight the need for proper regulations and routine monitoring to protect marine ecosystems and public health.…”
Get full text

Universal Design for Learning. A systematic review of its role in Teacher Education. by Sara De la Fuente-González, David Menéndez Álvarez-Hevia, Alejandro Rodríguez-Martín

“…This concept has been progressively incorporated into pedagogical debates and education regulations. Along this line, some publications have illustrated the efficacy of UDL in terms of access, participation, and commitment to learning processes, especially in the case of students with disabilities. …”
Get full text

High-Throughput Sequencing Reveals Diverse Sets of Conserved, Nonconserved, and Species-Specific miRNAs in Jute by Md. Tariqul Islam, Ahlan Sabah Ferdous, Rifat Ara Najnin, Suprovath Kumar Sarker, Haseena Khan

“…MicroRNAs play a pivotal role in regulating a broad range of biological processes, acting by cleaving mRNAs or by translational repression. …”
Get full text

Mere moral beliefs aren't sufficient to determine pro-social behaviors! A moderated mediation framework tested in healthcare settings based on Belief in Self-Determinism (BSD) Theo... by Muhammad Ali Asadullah, Tabassum Iqbal, Ali Haj Khalifa, Sajid Haider

“…This study offers some important implications for healthcare professionals to regulate healthcare professionals' prosocial based on their moral beliefs, moral attitudes, and professional experience.…”
Get full text

The Effect of Race, Sex, and Insurance Status on Time-to-Listing Decisions for Liver Transplantation by Cindy L. Bryce, Chung-Chou Ho Chang, Derek C. Angus, Robert M. Arnold, Maxwell Farrell, Mark S. Roberts

“…Processes leading to listing decisions are neither regulated nor understood. We explored whether patient characteristics affected timeliness of listing using population-based data on 144,507 adults hospitalized with liver-related disease in Pennsylvania. …”
Get full text