Dimensions of Rational Decision-Making during the Demographic Transition; Aranjuez (Spain) Revisited by David Reher, Glenn Sandström

“…The results offer convincing proof that couples were continually regulating their fertility in order to achieve reproductive goals both in terms of net fertility and of the sex composition of the resulting sibset. …”
Get full text

Digital national currency paradigm: risks and benefits by I. B. Rodina

“…Any digital currency of a particular country has specific features of calculations dictated by national features of the monetary system, conditions, goals and instruments of monetary policy. Most regulators evaluate the agreed options, study the potential consequences of using this mechanism, resort to the services of public experts, take into account the achievements of foreign specialists. …”
Get full text

Early changes in microRNA expression in Arabidopsis plants infected with the fungal pathogen Fusarium graminearum. by Savio S Ferreira, Suman Pandey, Jesseca Hemminger, Serdar Bozdag, Mauricio S Antunes

“…These short RNA molecules (20-22 nucleotides) have been shown to be important players in the early responses of plants to stresses because they can rapidly regulate the expression levels of a network of downstream genes. …”
Get full text

Law diversities for climate change: legal pluralism and climate governance in Indonesia by Muhammad Insan Tarigan, Raisha Hafandi

“…The process of formulating regulations in Indonesia is mainly top-down and neglects to consider the socio-economic rules of the society. …”
Get full text

Perfectionism and rational-emotive behaviour as a motivational policy for human resource management by Yu. A. Filyasova

“…Employees who find themselves in a corporate perfectionist culture have the advantage of achieving a high autonomy level due to developing integrative abilities for regulating social actions. Perfectionist motivational policy is more typical for the company`s growth cyclical stage and more beneficial for young people who have high goals regarding their professional development. …”
Get full text

Clean-Room Air Conditioning Control Based on Improved Min-Max Robust Model Predictive Control Algorithm by Qiang Luo, Ting Wang

“…Firstly, for the comfort of indoor air conditioning, the MPC algorithm is investigated to regulate the air conditioning air supply based on indoor temperature and humidity ratio in order to control the indoor comfort of the clean-room. …”
Get full text

Current state and development of police law as a subsystem of administrative law by O. A. Zhydovtseva

“…The main content of the police law structure as one of the sub-branches of administrative law is the legal norms that regulate the activities of the police and their internal organizational structure. …”
Get full text

Overview of Platelet Physiology: Its Hemostatic and Nonhemostatic Role in Disease Pathogenesis by Kakali Ghoshal, Maitree Bhattacharyya

“…Platelets are small anucleate cell fragments that circulate in blood playing crucial role in managing vascular integrity and regulating hemostasis. Platelets are also involved in the fundamental biological process of chronic inflammation associated with disease pathology. …”
Get full text

The Influence of Gibberellins and Smoke Water as a Stimulant for Germination and Vegetative Growth of Syzygium aromaticum (L.) Merr. & L. M. Perry by W. Muslihatin, R. P. D. Wahyudi, M. Iqbal, T. B. Saputro and T. Nurhidayati

“…Therefore, it is necessary to optimize the production of Indonesian cloves, one of which is by using growth stimulators such as plant growth regulators (PGR). This study uses gibberellic acid (GA3) and smoke water as exogenous growth triggers. …”
Get full text

Inhibiting HnRNP L-mediated alternative splicing of EIF4G1 counteracts immune checkpoint blockade resistance in Castration-resistant prostate Cancer by Xumin Zhou, Shilong Cheng, Zhongjie Chen, Jinming Zhang, Jiaqi Wang, Qiang Li, Xumin Zhou

“…In summary, this study revealled the molecular mechanism of HnRNP L regulating the immune infiltration, which provides a new theoretical basis for overcoming the limitation of immunotherapy for CRPC.…”
Get full text

Apelin Protects Primary Rat Retinal Pericytes from Chemical Hypoxia-Induced Apoptosis by Li Chen, Yong Tao, Jing Feng, Yan Rong Jiang

“…Pericytes are a population of cells that participate in normal vessel architecture and regulate permeability. Apelin, as the endogenous ligand of G protein-coupled receptor APJ, participates in a number of physiological and pathological processes. …”
Get full text

Pharmacological activity of OST-01, a natural product from baccharis coridifolia, on breast cancer cells by HyunJun Kang, Dinh Hoa Hoang, Melissa Valerio, Khyatiben Pathak, William Graff, Alexis LeVee, Jun Wu, Mark A. LaBarge, David Frankhouser, Russell C. Rockne, Patrick Pirrotte, Bin Zhang, Joanne Mortimer, Le Xuan Truong Nguyen, Guido Marcucci

“…Mechanistically, OST-01 induces ferroptosis by downregulating LRP8-regulated selenoproteins, i.e., GPX4. A shift from a basal-mesenchymal to a luminal-epithelial state of breast cancer stem cells (BCSCs) as supported by the downregulation of stemness (e.g., CD44) and mesenchymal (e.g., FN1 and vimentin) markers, along with the upregulation of differentiation markers (e.g., CD24) and luminal-epithelial markers (e.g., CK19), was also observed.…”
Get full text

Regenerative properties of bone marrow mesenchymal stem cell derived exosomes in rotator cuff tears by Junjie Chen, Zihe Wang, Ming Yi, Yi Yang, Mengzhao Tian, Yinqi Liu, Guoyou Wang, Huarui Shen

“…As a result, the healing process of rotator cuff injuries faces significant challenges.Bone marrow-derived mesenchymal stem cell exosomes (BMSC-exos) have emerged as a prominent focus of research within the field of bioengineering, owing to their remarkable potential to regulate cellular proliferation and differentiation, modulate immune responses, and facilitate tissue repair and regeneration following cellular damage. …”
Get full text

Agomelatine Efficacy in the Night Eating Syndrome by Walter Milano, Michele De Rosa, Luca Milano, Anna Capasso

“…This paper describes a case report of an NES patient treated with agomelatine, an antidepressant analogue of melatonin, which acts by improving not only the mood but also by regulating sleep cycles and appetite. After three months of observation, the use of Agomelatine not only improved the mood of our NES patient (assessed in the HAM-D scores) but it was also able to reduce the night eating questionnaire, by both reducing the number of nocturnal awakenings with food intake, the time of snoring, the minutes of movement during night sleep (assessed at polysomnography), and the weight (−5.5 kg) and optimizing blood glucose and lipid profile. …”
Get full text

Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction by Andrew C. Hiday, Michael C. Edler, Asma B. Salek, Cameron W. Morris, Morrent Thang, Tyler J. Rentz, Kristie L. Rose, Lisa M. Jones, Anthony J. Baucum

“…Our data determine mechanisms that regulate, and putative consequences of, pathological changes in the association of spinophilin with NF-M that are observed in animal models of PD.…”
Get full text

Long Noncoding RNA uc001pwg.1 Is Downregulated in Neointima in Arteriovenous Fistulas and Mediates the Function of Endothelial Cells Derived from Pluripotent Stem Cells by Lei Lv, Haozhe Qi, Xiangjiang Guo, Qihong Ni, Zezhen Yan, Lan Zhang

“…Recent studies indicate important roles for long noncoding RNAs (lncRNAs) as essential regulators of gene expression. However, the specific roles of lncRNAs in stenotic lesions of arteriovenous fistula (AVF) failure are still largely unknown. …”
Get full text

Pro- and Anti-Inflammatory Cytokines Release in Mice Injected with Crotalus durissus terrificus Venom by A. Hernández Cruz, S. Garcia-Jimenez, R. Zucatelli Mendonça, V. L. Petricevich

“…Taken together, these data indicate that the envenomation by Cdt is regulated both pro- and anti-inflammatory cytokine responses at time-dependent manner. …”
Get full text

Stromal Derived Factor-1/CXCR4 Axis Involved in Bone Marrow Mesenchymal Stem Cells Recruitment to Injured Liver by Kuai Xiao Ling, Li Peng, Zhang Jian Feng, Cao Wei, Yuan Wei Yan, Shao Nan, Guan Cheng Qi, Wang Zhi Wei

“…Taken together, the results demonstrated that the migration of BMSCs was regulated by SDF-1/CXCR4 signaling which involved in BMSCs recruitment to injured liver.…”
Get full text

Multi-Temporal Energy Management Strategy for Fuel Cell Ships Considering Power Source Lifespan Decay Synergy by Xingwei Zhou, Xiangguo Yang, Mengni Zhou, Lin Liu, Song Niu, Chaobin Zhou, Yufan Wang

“…With increasingly stringent maritime environmental regulations, hybrid fuel cell ships have garnered significant attention due to their advantages in low emissions and high efficiency. …”
Get full text

New insights into Notch signaling as a crucial pathway of pancreatic cancer stem cell behavior by chrysin-polylactic acid-based nanocomposite by Eman M. Ragab, Doaa M. El Gamal, Fares F. El-najjar, Hager A. Elkomy, Mahmoud A. Ragab, Mariam A. Elantary, Omar M. Basyouni, Sherif M. Moustafa, Shimaa A. EL-Naggar, Abeer S. Elsherbiny

“…Among these Notch signaling pathway has been identified as a key regulator of CSCs self-renewal, making it an attractive target for therapeutic intervention. …”
Get full text