Endothelial AGGF1 promotes retinal angiogenesis by coordinating TNFSF12/FN14 signalling by Ying Cheng, Man Zhang, Chenguang Li, Long Su, Lingli Fu, Shi Wu, Chaofei Xu, Bei Sun, Liming Chen

“…Mechanistic investigations demonstrate that HIF-1α directly regulates AGGF1 expression. AGGF1 upregulates the expression of cell cycle proteins by increasing the binding of tumour necrosis factor ligand superfamily member 12 (TNFSF12) to fibroblast -growth -factor-inducible 14 (FN14, TNFRSF12A). …”
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A review on probiotics and dietary bioactives: Insights on metabolic well-being, gut microbiota, and inflammatory responses by Alice Njolke Mafe, Great Iruoghene Edo, Osamah S. Majeed, Tayser Sumer Gaaz, Patrick Othuke Akpoghelie, Endurance Fegor Isoje, Ufuoma Augustina Igbuku, Joseph Oghenewogaga Owheruo, Rapheal Ajiri Opiti, Yasal Garba, Arthur Efeoghene Athan Essaghah, Dina S. Ahmed, Huzaifa Umar

“…It highlights the various types of probiotics in foods, their effects on immune function, and their role in regulating inflammatory response and metabolic well-being. …”
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Prion protein promotes copper toxicity in Wilson disease by Raffaella Petruzzelli, Federico Catalano, Roberta Crispino, Elena V. Polishchuk, Mariantonietta Elia, Antonio Masone, Giada Lavigna, Anna Grasso, Maria Battipaglia, Lucia Vittoria Sepe, Banu Akdogan, Quirin Reinold, Eugenio Del Prete, Diego Carrella, Annalaura Torella, Vincenzo Nigro, Enrico Caruso, Nicole Innocenti, Emiliano Biasini, Ludmila V. Puchkova, Alessia Indrieri, Ekaterina Y. Ilyechova, Pasquale Piccolo, Hans Zischka, Roberto Chiesa, Roman S. Polishchuk

“…Abstract Copper (Cu) is a vitally important micronutrient, whose balance between essential and toxic levels requires a tightly regulated network of proteins. Dysfunction in key components of this network leads to the disruption of Cu homeostasis, resulting in fatal disorders such as Wilson disease, which is caused by mutations in the hepatic Cu efflux transporter ATP7B. …”
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Comparative genomics and transcriptomic response to root exudates of six rice root-associated Burkholderia sensu lato species by Wallner, Adrian, Klonowska, Agnieszka, Guigard, Ludivine, King, Eoghan, Rimbault, Isabelle, Ngonkeu, Eddy, Nguyen, Phuong, Béna, Gilles, Moulin, Lionel

“…We further report the shared major functions that were differentially regulated in this early step of bacterial adaptation to plant colonization, including amino acids and putrescine metabolism, the Entner-Doudoroff (ED) pathway as well as cyclic diguanylate monophosphate (c-di-GMP) cycling. …”
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New insights into anti-depression effects of bioactive phytochemicals by Ruohan Zhao, Jingwen Wang, Sookja Kim Chung, Baojun Xu

“…Additionally, we summarize the potential mechanisms by which these phytochemicals prevent depression, including regulating neurotransmitters and their receptors, the HPA axis, inflammatory responses, managing oxidative stress, neuroplasticity, and the gut microbiome. …”
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Economic valuation of the thermal inertization of asbestos waste—an Italian case study by Silvia Ferrini, Filippo Pampaloni, Francesco Delogu, Giulia Goffetti, Cecilia Viti, Giancarlo Capitani

“…However, their success is contingent on securing public funding, a thorough examination of hidden environmental costs and risks, and the establishment of supportive regulations fostering a circular economy. These findings underscore the imperative for further exploration and substantial financial commitments to make asbestos treatment options a global reality.…”
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Regenerative therapies for myocardial infarction: exploring the critical role of energy metabolism in achieving cardiac repair by Jiahao Ren, Xinzhe Chen, Tao Wang, Cuiyun Liu, Kun Wang

“…Currently, a large number of studies have focused on changes in metabolic levels before and after the proliferation window of cardiomyocytes, so it is crucial to search for relevant factors in metabolic pathways to regulate the cell cycle in cardiomyocyte progression. …”
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Exploring the association between air pollution and the incidence of liver cancers by Xin Wu, Xin Zhang, Xiaopeng Yu, Hongyuan Liang, Shaoshan Tang, Yao Wang

“…The review emphasizes the need for stricter air quality regulations and relevant research for underlying mechanisms exposed to air pollution. …”
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A Comprehensive Study About the Contribution of Human Activities to The Pollution of River Rwabakazi Through its Tributaries Around Kabale Town. by Tumwesigire, Warren

“…Water is the most crucial factor in shaping the land and regulating the climate. It is an important component of living beings as it performs unique and indispensable activities on earth, ecosystems, biosphere, and biochemical cycles. …”
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Call to Action: Lead Pharmacy into the Next Decade by Gregory Zumach, Kerry K Fierke, Gardner Lepp, Bridget McGugan, Marta Brooks, Anthony Olson, Andrew Bartlett, Nilushi Karunaratne, Betty Exintaris

“…Pharmacy leaders feel that leadership is needed to make decisions, take accountability and, especially in an area as highly regulated as healthcare, ensure regulations and procedures are followed and standards are upheld. …”
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Emodin protects against severe acute pancreatitis-associated acute lung injury by activating Nrf2/HO-1/GPX4 signal and inhibiting ferroptosis in vivo and in vitro by Gang Shen, Haiyun Wen, Huijuan Li, Xuetao Zhang, Bowen Lan, Xuanchi Dong, Peng Ge, Yalan Luo, Hailong Chen

“…Moreover, these results also showed that EMO, contrary to the effects of ML385, suppressed the ferroptosis response, which manifested as up-regulated glutathione (GSH) and GPX4 levels in vivo and in vitro and down-regulated malondialdehyde (MDA), superoxide dismutase (SOD), Fe2+, and reactive oxygen species (ROS) levels. …”
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Menciptakan Layanan Pengawasan Ketenagakerjaan secara Profesional, Moderm dan Bermartabat Berbasis Teknologi Digital by Yeni Nuraeni, Nurlia Rahmatika, Firdausi Nuzula, Faizal Amir Nasution

“…The lack of socialization, guidance and granting of access rights by the Ministry of Manpower is an obstacle to using the Sisnaker and Siswasnaker applications. Strong regulations are needed in regulating coordination between relevant agencies in providing data and developing ICT in the field of labor inspection. …”
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Guidance and Counselling and Learners’ Discipline in Kasese District: A Case of Selected Government-Aided Secondary Schools in Bukonzo County. by Kule, Samson

“…Student leaders should be fully empowered and always involved in discipline management, budgeting process and decision-making especially when drafting the rules and regulations. Organs that offer counselling services should always be invited to inspire and inculcate appropriate moral education into the learners. …”
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Guidance and Counselling and Learners’ Discipline in Kasese District: A Case of Selected Government-Aided Secondary Schools in Bukonzo County. by Kule, Samson

“…Student leaders should be fully empowered and always involved in discipline management, budgeting process and decision-making especially when drafting the rules and regulations. Organs that offer counselling services should always be invited to inspire and inculcate appropriate moral education into the learners. …”
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Vivir la violencia materna. La voz de los niños y las niñas by Mauricio Hernando Bedoya, Mary Lucy Giraldo

“…Conclusiones: la violencia materna genera un estilo comunicacional fundamento en el desencuentro vincular; los niños y niñas que creen poder "torcer el destino", tienen unasestrategias de resistencia contra la violencia materna; el sentirse reconocido y captado en una trama vincular hace resilientes a los niños y niñas y, finalmente, se ratifica la importancia de un tercero que regule la violencia materna.…”
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O discurso de vereadores de um município do Estado de Minas Gerais: aproximações com a representação teatral e distanciamento da dialogicidade by Juliana Cristina Teixeira, Priscila Gomes de Araújo, Mariana Pereira Chaves Pimentel, Flávia Luciana Naves Mafra

“…The purpose of the performance by the aldermen is to direct and regulate the impression that the citizens might make of them, through the control of expression. …”
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Climate change and the single cell by Derek T. A. Lamport

“…Stomata act as crucial regulatory components of a water hypercycle that contributes to the homeostasis of a warming planet by regulating evaporative cooling and reflective cloud cover generated by vast tropical rainforests of the South and the equally vast arboreal forests of the North. …”
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From digitalization to green transformation: empirical evidence from RCEP’s industrial sectors by Lu Wan, Xiya Wan, Yanqi Fang, Guohua Huang

“…Our findings indicate that while the digitalization of services under the RCEP significantly propels the green technology development in China’s manufacturing, this beneficial effect is dampened by increasingly rigid regulations governing digital services trade. The operational proficiency and innovative capacity of the manufacturing sector emerge as pivotal mediators in this dynamic. …”
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INVESTIGATING THE COST EFFECTIVENESS OF BIODIESEL DISTRIBUTION IN INDONESIA by Herbert Wibert Victor Hasudungan, Elis Heviati, Sulthon Sjahril Sabaruddin, Sigit Hargiyanto

“…Given that fuel prices fluctuate periodically, we also argue that the cost differences between the regulated and formulated reference may arise due to i) the data inaccuracy of the diesel fuel consumption and ii) specific terms outlined in the agreement between the corresponding transporters and suppliers. …”
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Infrared and transcendental structure of two-loop supersymmetric QCD amplitudes by Gregor Kälin, Gustav Mogull, Alexander Ochirov, Bram Verbeek

“…The divergences are written in terms of scalar triangle integrals whose expressions are known to all orders in the dimensional regulator ϵ = (4 − D)/2. We also present integrated expressions for the full-color two-loop four-point amplitudes with both matter and vectors on external legs in which lower-weight terms also cancel using an appropriate IR scheme. …”
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