The interaction of tPA with NMDAR1 drives neuroinflammation and neurodegeneration in α-synuclein-mediated neurotoxicity by Daniel Torrente, Enming J. Su, Alí Francisco Citalán-Madrid, Gerald P. Schielke, Daniel Magaoay, Mark Warnock, Tamara Stevenson, Kris Mann, Flavie Lesept, Nathalie Delétage, Manuel Blanc, Erin H. Norris, Denis Vivien, Daniel A. Lawrence

“…However, its role in different brain regions such as the substantia nigra (SN) is largely unexplored. …”
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Amplifying children’s leadership roles and voice in decision-making through co-production in outside of school hours care: qualitative findings from the connect promote and protect... by Alyssa C. Milton, Alyssa C. Milton, Alyssa C. Milton, Kristin Ballesteros, Helen Hernandez, Yenni Hwang, Nick Glozier, Nick Glozier, Tom McClean, Haley M. LaMonica, Haley M. LaMonica, Karen Thorpe, Karen Thorpe, Ian B. Hickie, Ian B. Hickie

“…The Connect Promote and Protect Program (CP3), a social connection and wellbeing program that provides a structured method of co-producing with children, educators, and their OSHC communities, is examined.ObjectivesThis study aimed to explore the response to a co-production approach in OSHC settings as part of participation in the CP3.MethodsQualitative interviews and focus groups were conducted with 12 OSHC staff (educators, coordinators, managers, and volunteers) and 12 children attending OSHC as part of a wider mixed-methods implementation-effectiveness stepped-wedge trial of CP3 in 12 OSHC services located in urban and regional areas of New South Wales, Australia. Participants undertook semi-structured interviews/focus groups via multiple communication platforms (face-to-face, phone, and video-conferencing platforms). …”
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Metabolite Profiling and Association Analysis of Leaf Tipburn in Heat-Tolerant Bunching Onion Varieties by Tetsuya Nakajima, Reina Yamamoto, Kanako Matsuse, Masato Fuji, Koei Fujii, Sho Hirata, Mostafa Abdelrahman, Muneo Sato, Masami Yokota Hirai, Masayoshi Shigyo

“…The insights gained can also be applied to other crops and regions. This study investigates the effects of different summer growth conditions on the metabolite profile of heat-tolerant bunching onions with dark green leaf blade coloration and examines their association with leaf tipburn. …”
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Genome analysis of colistin-resistant Salmonella isolates from human sources in Guizhou of southwestern China, 2019–2023 by Jingtong Wu, Yongxian Wen, Lv You, Xiaoyu Wei, Xiaoyu Wei, Junhua Wang, Ge Zhu, Shijun Li

“…The genetic similarities between isolates from Guizhou and other regions suggested the possibility of international transmission or shared reservoirs of resistance. …”
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Machine learning for predicting neoadjuvant chemotherapy effectiveness using ultrasound radiomics features and routine clinical data of patients with breast cancer by Pu Zhou, Pu Zhou, Hongyan Qian, Pengfei Zhu, Jiangyuan Ben, Jiangyuan Ben, Guifang Chen, Qiuyi Chen, Lingli Chen, Jia Chen, Ying He, Ying He

“…These patients were randomly assigned to training and validation cohorts. Tumor regions of interest (ROI) were delineated, and radiomics features were extracted. …”
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The role of OCO-3 XCO₂ retrievals in estimating global terrestrial net ecosystem exchanges by X. Wang, F. Jiang, F. Jiang, F. Jiang, H. Wang, Z. Zhang, M. Wu, J. Wang, W. He, W. Ju, W. Ju, J. M. Chen, J. M. Chen

“…However, there are significant regional differences. Compared to the observed global annual CO<span class="inline-formula">₂</span> growth rate, Exp_OCO3 has the largest bias and Exp_OCO3&amp;2 shows the best performance. …”
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SO₂ emissions derived from TROPOMI observations over India using a flux-divergence method with variable lifetimes by Y. Chen, Y. Chen, R. J. van der A, J. Ding, H. Eskes, J. E. Williams, N. Theys, A. Tsikerdekis, P. F. Levelt, P. F. Levelt, P. F. Levelt

“…<p>The rapid development of the economy and the implementation of environmental policies adapted in India have led to fast changes of regional SO<span class="inline-formula">₂</span> emissions. …”
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Ibero-American consensus statement on migraine treatment by José Miguel Láinez, Oscar Pradilla, Pablo Irimia, Fidel Sobrino, Michel Volcy, Pedro Kowaks, Ildefonso Rodríguez Leyva, Fiorella Martín, Lucía Zavala, Alex Espinoza

“…These recommendations are based on the consensus process and a literature review, and are adapted to the regional conditions of the Ibero-American countries. …”
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The impact of E × B shear on microtearing based transport in spherical tokamaks by B.S. Patel, M.R. Hardman, D. Kennedy, M. Giacomin, D. Dickinson, C.M. Roach

“…At low $\hat{s}$ , the growth rate depends weakly on θ _0 , but at higher $\hat{s}$ , the MTM growth rate peaks at θ _0  = 0, with regions of stability at higher θ _0 . Equilibrium E  ×  B sheared flows act to advect the θ _0 of a mode in time, providing a mechanism to reduce the linear drive and suppress the transport from modes where the growth rate is strongly peaked in θ _0 (Roach et al 2009 Plasma Phys. …”
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A Phenologically Simplified Two-Stage Clumping Index Product Derived from the 8-Day Global MODIS-CI Product Suite by Ge Gao, Ziti Jiao, Zhilong Li, Chenxia Wang, Jing Guo, Xiaoning Zhang, Anxin Ding, Zheyou Tan, Sizhe Chen, Fangwen Yang, Xin Dong

“…This study provides relatively reliable CI datasets that capture the general trend of seasonal CI variations and simplify potential applications in modeling ecological, meteorological, and other surface processes at both global and regional scales. Therefore, this study provides both new perspectives and datasets for future research in relation to CI and other biophysical parameters, e.g., the LAI.…”
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Delta radiomics modeling based on CTP for predicting hemorrhagic transformation after intravenous thrombolysis in acute cerebral infarction: an 8-year retrospective pilot study by Xiaxia Wu, Xiaxia Wu, Jinfang Yang, Jinfang Yang, Xianqun Ji, Yingjian Ye, Ping Song, Lina Song, Peng An, Peng An

“…In the training set, regions of interest (ROI) within the cerebral infarction area on CTP images were delineated using 3D slicer software, and delta radiomic features were extracted. …”
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Prevalence and predictors of permanent pacemaker implantation in patients with aortic stenosis undergoing transcatheter aortic valve implantation: a prospective cohort study by Erlend Eriksen, Ronak Rajani, Sahrai Saeed, Svein Rotevatn, Daanyaal Wasim, Øyvind Bleie, Abukar Mohamed Ali, Erik Jerome Stene Packer, Håvard Keilegavlen

“…Permanent pacemaker implantation following TAVI had no impact on short or long-term survival.Ethics and dissemination The Regional Committees for Medical and Health Research Ethics (approval number: REK vest 33814/2019) and the Institutional Data Protection Services approved the study protocol. …”
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Cerebral microvascular density, blood-brain barrier permeability, and support for neuroinflammation indicate early aging in a Marfan syndrome mouse model by Tala Curry-Koski, Tala Curry-Koski, Liam P. Curtin, Mitra Esfandiarei, Mitra Esfandiarei, Mitra Esfandiarei, Theresa Currier Thomas, Theresa Currier Thomas, Theresa Currier Thomas, Theresa Currier Thomas

“…Glut1 immunostaining was used to quantify microvascular density, IgG staining to assess BBB permeability, and microglial counts to evaluate neuroinflammation.ResultsUsing Glut1 staining, 6M-MFS mice and 12M-CTRL similarly present decreased microvascular density in the dentate gyrus (DG), cornu ammonis 1 (CA1), and cornu ammonis 3 (CA3) regions of the hippocampus. 6M-MFS mice exhibit increased BBB permeability in the DG and CA3 as evident by Immunoglobulin G (IgG) staining. …”
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Lithuanian, Russian, Polish istoriography with respect to the Poland - Lithuania union by Mečislovas Jučas

“…The political life, under conditions of full decentralization, was determined by the federation of regions (mainly Russian ones). The disputes concerned only the nature of the ethnos: whether it was Russian or Byelorussian during the 15th and 16th centuries. …”
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Economic and environmental sustainability of agriculture production at the crop level by A.Z. Bi, K.B. Umesh, B. Md Abdul, D. Sivakumar, P. Srikanth

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Pengembangan Aplikasi Sistem Informasi Pendataan Bangunan (SIPBANG) pada Dinas Pekerjaan Umum dan Penataan Ruang (DPUPR) Kota Malang Menggunakan Framework Scrum by Muhamad Rifky, Yusi Tyroni Mursityo, Bondan Sapta Prakoso

“…Abstract The City of Malang Public Works and Spatial Planning Department (DPUPR) is the department responsible for regional planning, infrastructure, building, and others. …”
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Studying the Beneficial Indicators of Intercropping of Safflower (Carthamus tinctorius L.) with Chickpea (Cicer arietinum L.), Lentil (Lens culinaris Medik), and Bitter Vetch (Lath... by Amin Yari, Farzad Mondani, Alireza Bagheri, Hamid Reza Chaghazardi

“…Therefore, if the results of this study are confirmed in other years and regions under dryland conditions, the chickpea-safflower intercropping with a 50:50 pattern is recommended.…”
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Impact of iron chelation with deferasirox on telomere length and oxidative stress in hemodialysis patients: A randomized study by Blanca Olivia Murillo Ortiz, Joel Ramírez Emiliano, Marcos Javier Romero Vázquez, Lauro Fabián Amador Medina, Sandra Martínez Garza, Edna Montserrat Ramos Rodríguez

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The Effect of Wheat Residues and Vermicompost on the Quality Characteristics of Corn (Zea mays L.) Forage and Soil Fertility by Hasanali Pooresmaeil, Mehdi Dahmradeh, Ahmad Ghanbari

“…IntroductionOne of the most significant agricultural challenges in arid and semi-arid regions is the decline in organic matter in agricultural soils, which leads to reduced crop yields and increased production costs. …”
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Meat characteristics of buffaloes (Bubalus bub- alis) in two production systems and two slaugh- ter weights by David Hernández-Sánchez, René Rodríguez-Florentino, Luis A. de la Cruz-Cruz, Efrén Ramírez-Bribiesca, María M. Crosby Galván, Miguel Á. Mata-Espinosa, René Pinto-Ruiz

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