Traces of Paleolithic expansion in the Nivkh gene pool based on data on autosomal SNP and Y chromosome polymorphism by V. N. Kharkov, N. A. Kolesnikov, L. V. Valikhova, A. A. Zarubin, A. L. Sukhomyasova, I. Yu. Khitrinskaya, V. A. Stepanov

“…Phylogenetic analysis of individual Y chromosomal haplogroups demonstrated the closeness of the Nivkh gene pool with the ancient population of the Amur and Okhotsk regions, the Koryaks, the Tungus peoples and the population of Southeast Asia. …”
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CD2AP deficiency aggravates Alzheimer’s disease phenotypes and pathology through p38 MAPK activation by Yan-Yan Xue, Zhe-Sheng Zhang, Rong-Rong Lin, Hui-Fen Huang, Ke-Qing Zhu, Dian-Fu Chen, Zhi-Ying Wu, Qing-Qing Tao

“…Results CD2AP is widely expressed in various regions of the mouse brain, with predominant expression in neurons and vascular endothelial cells. …”
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The effectiveness analysis of traditional and new landscape indexes in indicating flood risk of watersheds from the perspective of source-sink landscapes: A case study of Changsha,... by Lingxuan Zhang, Sheng Jiao, Jie Lu

“…Furthermore, they can serve as a reference for flood risk management in other regions with similar conditions.…”
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Size-resolved Compositional Analysis and Source Apportionment of Submicron Aerosol during Lockdown Period Using HR-ToF-AMS by Prodip Acharja, Akash Vispute, Prasanna Lonkar, Suresh W. Gosavi, Sreyashi Debnath, Narendra G. Dhangar, Kaushar Ali, Gaurav Govardhan, Sachin D. Ghude

“…The back trajectories, cluster analysis, and potential source contribution function (PSCF) showed the industrial belt located in the western part of the study location to be the potential source regions of NR-PM1. Positive matrix factorization (PMF) analyses have been applied to investigate the source apportionments of organic aerosols (OA). …”
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Description of the Serological Response After Treatment of Chronic Imported Schistosomiasis by Marta González-Sanz, Irene Martín-Rubio, Oihane Martín, Alfonso Muriel, Sagrario de la Fuente-Hernanz, Clara Crespillo-Andújar, Sandra Chamorro-Tojeiro, Begoña Monge-Maíllo, Francesca F. Norman, José A. Pérez-Molina

“…Conclusions: Serial serological determinations could be helpful for monitoring chronic schistosomiasis in non-endemic regions. The ideal timing for these follow-up tests is yet to be determined. …”
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Detection of low frequency artemisinin resistance mutations, C469Y, P553L and A675V, and fixed antifolate resistance mutations in asymptomatic primary school children in Kenya by Victor Osoti, Kevin Wamae, Leonard Ndwiga, Paul M. Gichuki, Collins Okoyo, Stella Kepha, Kibor Keitany, Regina Kandie, Stephen Aricha, Rosebella Kiplagat, Charles Mwandawiro, Philip Bejon, Robert W. Snow, Lynette Isabella Ochola-Oyier

“…Conclusion The genomic surveillance of asymptomatic school children in Kenya provides an early warning signal of at least 1 of the 3 validated artemisinin resistance mutations circulating in all regions in Western Kenya sampled except Homa Bay and Kisii Counties. …”
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Global decadal measurements of methanol, ethene, ethyne, and HCN from the Cross-track Infrared Sounder by K. C. Wells, D. B. Millet, J. F. Brewer, V. H. Payne, K. E. Cady-Pereira, R. Pernak, S. Kulawik, S. Kulawik, C. Vigouroux, N. Jones, E. Mahieu, M. Makarova, T. Nagahama, I. Ortega, M. Palm, K. Strong, M. Schneider, D. Smale, R. Sussmann, M. Zhou

“…The results reveal robust global distributions of the target VOCs from known biogenic, biomass burning, and industrial source regions, and they demonstrate the impact of anomalous events such as the 2015–2016 El Niño. …”
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Multi-Feature Driver Variable Fusion Downscaling TROPOMI Solar-Induced Chlorophyll Fluorescence Approach by Jinrui Fan, Xiaoping Lu, Guosheng Cai, Zhengfang Lou, Jing Wen

“…Additionally, a time series analysis of Shandong Province’s wheat-growing areas revealed a strong correlation (R² > 0.8) between SIF and multiple vegetation indices, underscoring its utility for regional crop monitoring.…”
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Guar, jantar, wheat straw, and rice hull composts as replacements for peat in muskmelon transplant production by Ghulam Mustafa, Muhammad Arif Ali, Donald Smith, Timothy Schwinghamer, John R. Lamont, Niaz Ahmed, Sajjad Hussain, Muhammad Arshad

“…Economic constraints paired with concerns over the sustainability of peat mining have necessitated the replacement of peat with renewable and regionally abundant alternatives. The aim of this study was to develop from composts complete or partial substitutes for peat. …”
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Genetic structure and evolutionary diversity of mating-type (MAT) loci in Hypsizygus marmoreus by Gang Wang, Yuanyuan Wang, Lianfu Chen, Hongbo Wang, Lin Guo, Xuan Zhou, Meijie Dou, Baiyu Wang, Jingxian Lin, Lei Liu, Zhengchao Wang, Youjin Deng, Jisen Zhang

“…Comparative analysis of the MAT regions among 73 Basidiomycete species indicated that the diversity of HD and P/R loci in Agaricales and Boletales may contribute to mating compatibility. …”
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Global burden and cross-country inequalities of nutritional deficiencies in adults aged 65 years and older, 1990–2021: population-based study using the GBD 2021 by Shuang Liang, Shao-Zhi Xi, Jia-Yi Liu, Gui-Chun Tang, Wei-Guang Zhang, Xin-Ru Guo, Chen Yang, Chun Zhang, Guang-Yan Cai

“…Methods Age-standardised prevalence, disability-adjusted life years (DALYs), and average annual percentage changes (AAPCs) of these deficiencies in people aged ≥ 65 years at global, regional, and national levels were estimated from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021. …”
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Deep-learning-based canopy height model generation from sub-meter resolution panchromatic satellite imagery by Charles J Abolt, Javier E Santos, Adam L Atchley, Lucas Wells, Daithi Martin, Russell A Parsons, Rodman R Linn

“…Because the model operates on satellite data with global coverage and a relatively short return interval, we propose its suitability to extrapolate tree-level canopy height data to remote regions and conduct high-temporal resolution monitoring of forest structure. …”
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Linking weather and climate information services (WCIS) to Climate-Smart Agriculture (CSA) practices by Tafadzwanashe Mabhaudhi, Tinashe Lindel Dirwai, Cuthbert Taguta, Aidan Senzanje, Wuletawu Abera, Ajit Govid, Elliott Ronald Dossou-Yovo, Ermias Aynekulu, Vimbayi Grace Petrova Chimonyo

“…, and (3) How can linking WCIS and CSA facilitate the identification, appraisal and prioritization of regionally differentiated and context-specific climate-appropriate technologies and policies that enhance agricultural water management at various levels (field, farm, scheme, and catchment)? …”
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Management of CAR-T cell therapy in patients with multiple myeloma: a systematic review and expert consensus in Australia by P. Joy Ho, Hang Quach, M. Hasib Sidiqi, M. Hasib Sidiqi, Cindy H. Lee, Jason Butler, Andrew Spencer, Kenneth Micklethwaite, Kenneth Micklethwaite, Kenneth Micklethwaite, Kenneth Micklethwaite, Jingya Li, Elissa Cusson, Robert Bagnall, Simon J. Harrison

“…Consensus was defined a priori as at least 70% agreement on survey questions.ResultsThe SLR identified 22 interventional or observational studies and 5 clinical practice guidelines reporting on selection and management of patients with MM treated with CAR-T cell therapy from various global regions. The Delphi panel reached consensus on practices related to patient referral, screening, selection, prioritization, treatments requiring wash-out, bridging therapy, lymphodepletion, infusion, and post-infusion monitoring and management. …”
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Therapeutic Efficacy of <i>Lavandula dentata</i>’s Oil and Ethanol Extract in Regulation of the Neuroinflammation, Histopathological Alterations, Oxidative Stress, and Restoring Ba... by Aziza Antar, Eman S. Abdel-Rehiem, Areej A. Al-Khalaf, Abdelaziz S. A. Abuelsaad, Mohamed Abdel-Gabbar, Gaber M. G. Shehab, Ayman M. Abdel-Aziz

“…Additionally, histological changes in various brain regions were investigated. <b>Results</b>: The investigation revealed that the extract and essential oils obtained from <i>L. dentata</i> L. exhibited the ability to improve the modulation of electrolytes and ions across voltage- and ligand-gated ion channels. …”
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Multidimensional analysis and enhancement strategies for ecological environment quality at the county level under dual carbon goals: a case study of Shaanxi Province, China by Jianfeng Li, Jianfeng Li, Jianfeng Li, Yongxin Hu, Yongxin Hu, Jian Li, Liangyan Yang, Liangyan Yang, Jie Yan

“…The results indicate that: 1) From 2000 to 2020, the overall EEQ in Shaanxi Province showed a fluctuating upward trend, improving from a moderate level to a good level, although some counties experienced slight degradation from 2010 to 2020. 2) The spatial distribution of county-level EEQ displayed a “low-high-low-high” gradient from north to south, indicating superior ecological conditions in the southern and central-northern counties, while northern regions faced significant ecological challenges. 3) The future trend of EEQ in Shaanxi Province is expected to be one of continuous improvement, although attention must be paid to the ongoing degradation risks in highly urbanized areas. 4) The spatial differentiation of county-level EEQ is primarily driven by climate factors and influenced by the synergistic effects of multiple factors. …”
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Experimental prosopis management practices and grassland restoration in three Eastern African countries by René Eschen, Ketema Bekele, Yohana Jumanne, Staline Kibet, Fernadis Makale, John Richard Mbwambo, Berhanu Megersa, Mahamood Mijay, Francis Moyo, Linus Munishi, Mickfanaka Mwihomeke, Winnie Nunda, Moses Nyangito, Arne Witt, Urs Schaffner

“…The three-year study was replicated in Ethiopia (Afar National Regional State), Kenya (Baringo county) and Tanzania (Moshi district). …”
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Targeting CXCL8 signaling sensitizes HNSCC to anlotinib by reducing tumor-associated macrophage-derived CLU by Xin Hu, Yikang Ji, Mi Zhang, Zhihui Li, Xinhua Pan, Zhen Zhang, Xu Wang

“…Conclusion Our results provide novel evidence of a feedback loop between cancer cells and TAMs in glucose-deficient regions. HNSCC-derived CXCL8 favors endogenous antioxidative processes and confers therapeutic resistance to nutrient-starvation therapies in HNSCC. …”
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The Impact of Optical Undersampling on the Ca2+ Signal Resolution in Ca2+ Imaging of Spontaneous Neuronal Activity by Katarina D. Milicevic, Violetta O. Ivanova, Tina N. Brazil, Cesar A. Varillas, Yan M.D. Zhu, Pavle R. Andjus, Srdjan D. Antic

“…In neurons bulk-loaded with OGB1-AM, cell nucleus-mediated signal distortions were observed in every neuron examined (n = 57). Specifically, two regions of interest (ROIs) on different segments of the same cell body displayed significantly different signal amplitudes and durations due to dye accumulation in the nucleus. …”
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Perspective of Need for First Aid Education in Bulgarian Schools by Daniela Baleva

“…Methods: A sample of 419 teachers from 26 public and private schools in different cities, towns, and villages in all the six NUTS 2 level regions in Bulgaria filled in questionnaires in order to examine their current level of first aid and disaster response training and motivation for improving it. …”
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