The impact of channel density, inverse solutions, connectivity metrics and calibration errors on OPM-MEG connectivity analysis: A simulation study by Shengjie Qi, Xinda Song, Le Jia, Hongyu Cui, Yuchen Suo, Tengyue Long, Zhendong Wu, Xiaolin Ning

“…Synthetic MEG data corresponding to two default mode networks (DMN) with six or ten DMN regions were generated using the Gaussian Graphical Spectral (GGS) model. …”
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Management of tuberculosis risk, screening and preventive therapy in patients with chronic autoimmune arthritis undergoing biotechnological and targeted immunosuppressive agents by Andrea Picchianti-Diamanti, Alessandra Aiello, Chiara De Lorenzo, Giovanni Battista Migliori, Delia Goletti

“…As conceivable, the risk is associated with age ≥65 years and is higher in endemic regions, but immunosuppressive therapy plays a pivotal role. …”
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Metabolomic profiles of <i>Ribes nigrum</i> L. and <i>Lonicera caerulea</i> L. from the collection of the N.I. Vavilov Institute in the setting of Northwest Russia by T. V. Shelenga, V. S. Popov, A. V. Konarev, N. G. Tikhonova, O. A. Tikhonova, Y. A. Kerv, A. E. Smolenskaya, L. L. Malyshev

“…Because the direction of use depends on the biochemical properties of fruits, which are determined not only by species and varietal characteristics, but also by reproduction conditions, the study of the biochemical composition of fruits grown in various regions of the world continues to be relevant. In this regard, the collection of N.I. …”
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Enhanced Interleukin 6 Trans-Signaling Modulates Disease Process in Amyotrophic Lateral Sclerosis Mouse Models by Carol Milligan, Dale O. Cowley, William Stewart, Alyson M. Curry, Elizabeth Forbes, Brian Rector, Annette Hastie, Liang Liu, Gregory A. Hawkins

“…Intense research efforts have provided insight into unique neuroanatomical regions, specific neuronal populations and genetic associations for ALS and other neurodegenerative diseases; however, the experimental results also suggest a convergence of these events to common toxic pathways. …”
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Personalized optimization of systematic prostate biopsy core number based on mpMRI radiomics features: a large-sample retrospective analysis by Zhenlin Chen, Zhihao Li, Ruiling Dou, Shaoqin Jiang, Shaoshan Lin, Zequn Lin, Yue Xu, Ciquan Liu, Zijie Zheng, Yewen Lin, Mengqiang Li

“…The MRI data were collected to manually segment Regions of Interest (ROI) of the tumor layer by layer. …”
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Deep Learning-Based Fully Automatic Segmentation of the Paranasal Sinuses in Chronic Rhinosinusitis Patients Using Computed Tomographic Images by Yuhang Wang, Xiaolei Zhang, Weidong Du, Na Dai, Yi Lyv, Keying Wu, Yiyang Tian, Yuxin Jie, Yu Lin, Weipiao Kang

“…This paper introduces a 3D semantic segmentation technology to achieve fully automatic 3D segmentation of sinus lesion regions, allowing physicians to observe the anatomical structures and lesions in the sinuses more clearly, thereby improving the diagnostic accuracy for CRSwNP. …”
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Assessing the effect of beta-propiolactone inactivation on the antigenicity and immunogenicity of cluster 2.1 duck Tembusu virus by Kanana Rungprasert, Wikanda Tunterek, Phornphisut Areeraksakul, Duangduean Prakairungnamthip, Chalida Sri-in, Navapon Techakriengkrai, Wijit Banlunara, Christine A. Jansen, Teerawut Nedumpun, Aunyaratana Thontiravong

“…Therefore, developing vaccines based on virus clusters specific to regions is essential. To generate an effective inactivated vaccine, the virus inactivation procedure must be optimized for each virus strain. …”
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Prevalence and Predictors of Self-Reported Sexual Abuse in Severely Obese Patients in a Population-Based Bariatric Program by Danielle L. Gabert, Sumit R. Majumdar, Arya M. Sharma, Christian F. Rueda-Clausen, Scott W. Klarenbach, Daniel W. Birch, Shahzeer Karmali, Linda McCargar, Konrad Fassbender, Raj S. Padwal

“…We analyzed data from 500 consecutively recruited obese subjects from a population-based, regional bariatric program. The prevalence of self-reported sexual abuse was ascertained using a single interview question. …”
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Resistance to causal agents of late blight and golden potato nematode of the modern cultivars of seed potatoes and their phytosanitary status in various agroclimatic zones of the E... by A. V. Khiutti, D. A. Rybakov, T. A. Gavrilenko, O. S. Afanasenko

“…Rhizoctonia solani, Fusarium spp. and Helminthosporium solani are most common on all varieties. 100 % defeat of tubers by H. solani was recorded in various regions on the cultivars Red Scarlett, Evolution, Labella, Colombo, Gala and Nevsky. …”
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Long-term results of treatment of right-sided colon cancer with mesocolic excision and D3-lymph node dissection by S. K. Efetov, I. A. Tulina, A. Yu. Kravchenko, D. N. Fedorov, S. V. Efetov, P. V. Tsarkov

“…In patients with D2-lymph node dissection the involvement of regional lymph nodes was significant prognostic factor deteriorating overall 5-years survival rate (p=0,039) while at D3-lymph node dissection this factor had no effect on the prognosis (p=0,535).Conclusion. …”
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Based on the Gaussian Fitting Method to Derive Daily Evapotranspiration from Remotely Sensed Instantaneous Evapotranspiration by Suhua Liu, Hongbo Su, Renhua Zhang, Jing Tian, Shaohui Chen, Weimin Wang, Lijun Yang, Hong Liang

“…Evapotranspiration (ET) is a significant component in the water cycle, and the estimation of it is imperative in water resource management. Regional ET can be derived by using remote sensing technology which combines remote sensing inputs with ground-based measurements. …”
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MR Imaging of Prostate Cancer: Diffusion Weighted Imaging and (3D) Hydrogen 1 (1H) MR Spectroscopy in Comparison with Histology by J. Yamamura, G. Salomon, R. Buchert, A. Hohenstein, J. Graessner, H. Huland, M. Graefen, G. Adam, U. Wedegaetner

“…The prostate was divided into sextants. Regions of interest were placed in each sextant to evaluate the apparent diffusion coefficient (ADC)-values. …”
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Identifying biomarkers for epilepsy after cerebral malaria in Zambian children: rationale and design of a prospective observational study by Bo Zhang, Archana A Patel, Gretchen L Birbeck, Maitreyi Mazumdar, Suzanna Mwanza, Rosemary Nyirongo, Dixon Berejena, Joseph Kasolo, Tina Mwale, Violet Nambeye, Kafula Lisa Nkole, Nfwama Kawatu, Alexander Rotenberg

“…Our goal is to develop a predictive PME index composed of EEG and clinical history metrics that are highly feasible to obtain in low-resourced regions.Methods and analyses This prospective observational study being conducted in Eastern Zambia will recruit 250 children aged 6 months to 11 years presenting with acute CM and follow them for two years. …”
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Domain‐Specific Prediction of Clinical Progression in Parkinson's Disease Using the Mosaic Approach by Marlene Tahedl, Ulrich Bogdahn, Bernadette Wimmer, Dennis M. Hedderich, Jan S. Kirschke, Claus Zimmer, Benedikt Wiestler

“…We then identified cortical regions corresponding to “extremity functions” and restricted MAP, respectively, and contrasted the explanatory power of the extremity‐specific MAP to unrestricted MAP. …”
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Neuromuscular Excitation Pattern in Expert Indoor Skydivers by Susanna Rampichini, Eloisa Limonta, Irene Di Giulio, Marta Borrelli, Emiliano Cè, Giuseppe Coratella, Johnny Padulo, Stefano Longo, Fabio Esposito

“…The neuromuscular load (NeLo), representative of the excitation amplitude of a muscle set, was determined for each position across different body regions. PRONE and SUPINE were the least demanding in terms of cardiac engagement (67 ± 6 and 85 ± 8 bpm, respectively) and exhibited the lowest neuromuscular excitation (24 ± 10 and 24 ± 8% Max, respectively). …”
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GlucoGenes^®, a database of genes and proteins associated with glucose metabolism disorders, its description and applications in bioinformatics research by V. V. Klimontov, K. S. Shishin, R. A. Ivanov, M. P. Ponomarenko, K. A. Zolotareva, S. A. Lashin

“…When analyzing single nucleotide polymorphism (SNP) in the proximal regions of promoters affecting the affinity of the TATA-binding protein, 181 SNP markers were found in the GlucoGenes® database, which can reduce (45 SNP markers) or increase (136 SNP markers) the expression of 52 genes. …”
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Serum IL-18 Is a Potential Biomarker for Predicting Severe Dengue Disease Progression by Josephine Diony Nanda, Chiau-Jing Jung, Rahmat Dani Satria, Ming-Kai Jhan, Ting-Jing Shen, Po-Chun Tseng, Yung-Ting Wang, Tzong-Shiann Ho, Chiou-Feng Lin

“…Dengue virus (DENV) infection is the most common arboviral disease that affects tropical and subtropical regions. Based on the clinical hallmarks, the different severities of patients range from mild dengue fever (MDF) to severe dengue diseases (SDDs) and include dengue hemorrhagic fever or dengue shock syndrome. …”
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Suppression of Proinflammatory Cytokines and Mediators in LPS-Induced RAW 264.7 Macrophages by Stem Extract of Alternanthera sessilis via the Inhibition of the NF-κB Pathway by Katyakyini Muniandy, Sivapragasam Gothai, Khaleel M. H. Badran, S. Suresh Kumar, Norhaizan Mohd Esa, Palanisamy Arulselvan

“…Alternanthera sessilis, an edible succulent herb, has been widely used as herbal drug in many regions around the globe. Inflammation is a natural process of the innate immune system, accompanied with the increase in the level of proinflammatory mediators, for example, nitric oxide (NO) and prostaglandin (PGE2); cytokines such as interleukin 6 (IL-6), interleukin 1β (IL-1β), and tumor necrosis factor alpha (TNFα); and enzymes including inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) via the activation and nuclear translocation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) subunit p65 due to the phosphorylation of inhibitory protein, IκBα. …”
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Impact of secondary ice production on thunderstorm electrification under different aerosol conditions by S. Huang, J. Yang, J. Yang, J. Li, Q. Chen, Q. Zhang, F. Guo

“…It is found that as the aerosol concentration increases, more but smaller cloud droplets can be lofted to mixed-phase regions. The warm-rain process is suppressed, and the declined raindrop concentration leads to fewer graupel particles. …”
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A hypomorphic mutation in the mouse Csn1s1 gene generated by CRISPR/Cas9 pronuclear microinjection by A. V. Smirnov, T. A. Shnaider, A. N. Korablev, A. M. Yunusova, I. A. Serova, N. R. Battulin

“…Most of the known mutations affecting casein genes’ expression are located in the promoter and 3’-untranslated regions. We performed pronuclear microinjections with Cas9 mRNA and sgRNA against the first coding exon of the mouse Csn1s1 gene to introduce random mutations in the α-casein (Csn1s1) signal peptide sequence at the beginning of the mouse gene. …”
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