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23461
Aberrant methylation of placental development genes in chorionic villi of spontaneous abortions with trisomy 16
Published 2024-04-01“…To obtain sequencing libraries, targeted amplification of individual gene regions using designed oligonucleot ide primers for bisulfite-converted DNA was used. …”
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23462
Clinical outcomes of dogs with high-grade cutaneous mast cell tumors
Published 2025-01-01“…The limited therapeutic benefit of locoregional lymph node extirpation, combined with a persistently high metastatic rate despite systemic chemotherapy, highlights the critical need for more effective regional and systemic treatment approaches for HGMCT patients.…”
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23463
Brain Functional Network in Chronic Asymptomatic Carotid Artery Stenosis and Occlusion: Changes and Compensation
Published 2020-01-01“…In patients with CAS and CAO, the nodal efficiency of key nodes in multiple brain regions decreased, while the affected hemisphere lost many key functional connections. …”
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23464
Results of experimental infection of vaccinated and non-vaccinated ducklings with duck hepatitis virus
Published 2022-12-01“…This infection is included in the list of notifiable diseases of the World Organization for Animal Health, restrictive measures are established and the regionalization of the country’s territory is carried out in case of its occurrence. …”
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23465
Barriers and enablers to recruiting participants within paediatric perioperative and anaesthetic settings: lessons learned from a trial of melatonin versus midazolam in the premedi...
Published 2025-03-01“…The MAGIC trial highlighted variations within anaesthetic practice at individual, local, and regional levels. Lessons learned from the MAGIC trial identifies specific barriers to paediatric trial enrolment, offer solutions and discusses ongoing challenges. …”
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23466
New Echocardiographic Findings Correlate with Intramyocardial Inflammation in Endomyocardial Biopsies of Patients with Acute Myocarditis and Inflammatory Cardiomyopathy
Published 2013-01-01“…Speckle tracking echocardiography with accurate assessments of regional contractility could have an outstanding importance for the diagnosis. …”
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23467
Site Selection of Landfill with emphasis on Hydrogeomorphological – environmental parameters Shahrood-Bastam watershed
Published 2016-12-01“…The results of this research will be fruitful in systemic management approach of urban regions…”
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23468
Novel immunochromatographic test for rapid detection of anti-factor H autoantibodies with an assessment of its clinical relevance
Published 2025-01-01“…In pediatric aHUS, the FHAA incidence is ~10-15%, although in the Indian population, it rises to ~50%. The specific regions of FH targeted by FHAAs correlate with the pathogenic mechanism of the associated disease. …”
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23469
Evidence and perspectives on miRNA, circRNA, and lncRNA in myocardial ischemia-reperfusion injury: a bibliometric study
Published 2025-01-01“…Furthermore, bibliometric and visualization analyses of countries/regions, institutions, authors, keywords, and references were conducted using the bibliometric visualization software CiteSpace. …”
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23470
Early Electrophysiological Disintegration of Hippocampal Neural Networks in a Novel Locus Coeruleus Tau-Seeding Mouse Model of Alzheimer’s Disease
Published 2019-01-01“…Alzheimer’s disease (AD) is a progressive, neurodegenerative disease characterized by loss of synapses and disrupted functional connectivity (FC) across different brain regions. Early in AD progression, tau pathology is found in the locus coeruleus (LC) prior to amyloid-induced exacerbation of clinical symptoms. …”
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23471
Molecular characterization of EBV-associated primary pulmonary lymphoepithelial carcinoma by multiomics analysis
Published 2025-01-01“…Integration of EBV associated dysregulation of gene expression, with CNV-altered regions coinciding with EBV integration sites. Specifically, ZBTB16 and ERRFI1 were downregulated by CNV loss, and the FOXD family genes were overexpressed with CNV gain. …”
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23472
Differential Signature of the Centrosomal MARK4 Isoforms in Glioma
Published 2011-01-01“…Accordingly, only MARK4L is expressed in brain neurogenic regions. Moreover, while both MARK4 isoforms are localised to the centrosome and midbody in glioma and normal cells, the L isoform exhibits an additional nucleolar localisation in tumour cells. …”
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23473
Carotenoids and carotenes in the fruits of <i>Cucurbita maxima</i>, <i>C. moschata</i> and <i>C. pepo</i> under the conditions of Northwestern Russia
Published 2023-04-01“…The identified Cucurbita accessions with high content of carotenes and carotenoids can be used as valuable source material for breeding cultivars with improved biochemical composition, which can broaden the range of functional food products when grown in the regions with unfavorable conditions for the production of this crop.…”
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23474
The multifaceted power of biochar: A review on its role in pollution control, sustainable agriculture, and circular economy
Published 2025-01-01“…It explores the development of a circular economy-based environmental management paradigm, leveraging waste conversion into biochar and its diverse applications across regions, thus effectively closing the loop and exemplifying a truly circular economy in action.…”
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23475
Dynamic alterations in spontaneous neural activity in patients with attention-deficit/hyperactivity disorder: A resting-state fMRI study
Published 2025-03-01“…Finally, we developed an auxiliary diagnosis model. Results: Brain regions with increased dALFF variability of ADHD were located in right middle frontal gyrus (MFG), left inferior parietal lobe (IPL) and superior parietal gyrus (SPG) compared with HCs. …”
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23476
TRPV4 modulates inflammatory responses and apoptosis in enteric glial cells triggered by Clostridioides difficile toxins A and B
Published 2025-01-01“…CDI significantly upregulates TRPV4 in the cecum and colon’s submucosal and myenteric plexus regions. TRPV4 mediates TNF-α release in EGCs and is partially involved in the increase in IL-6 gene expression triggered by these toxins. …”
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23477
The effects of vessel speed and size on the lethality of strikes of large whales in U.S. waters
Published 2025-02-01“…This difference may be associated with data limitations, differing behavioral responses between species, varying vessel types between regions or differences in body composition and blubber thickness. …”
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23478
Comparison of Initial Clinical Presentations between Primary Hyperparathyroidism Patients from New Brunswick and Changsha
Published 2018-01-01“…Patients in Changsha had lower T-scores and Z-scores in both the lumbar spine and hip regions than those in New Brunswick (p<0.05). Patients in New Brunswick had lower percentages of parathyroid adenoma and kidney stones. …”
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23479
Endogenous Estrogen Influences Predator Odor-Induced Impairment of Cognitive and Social Behaviors in Aromatase Gene Deficiency Mice
Published 2021-01-01“…In addition, the changes in brain regional neurotransmitters and their associations with TMT-induced changes in behaviors were further investigated in these animals. …”
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23480
Multi-omics analyses identify gut microbiota-fecal metabolites-brain-cognition pathways in the Alzheimer’s disease continuum
Published 2025-02-01“…We also observed progressive gray matter atrophy in broadly distributed gray matter regions and gradual micro-structural integrity damage in widespread white matter tracts along the AD continuum. …”
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