Differential regulation of apoptosis-related genes during long-term culture and differentiation of canine adipose-derived stem cells - a functional bioinformatical analysis by Maurycy Jankowski, Maurycy Jankowski, Maurycy Jankowski, Katarzyna Stefańska, Michał Suchodolski, Claudia Dompe, Claudia Dompe, Grzegorz Wąsiatycz, Bartosz Kempisty, Bartosz Kempisty, Bartosz Kempisty, Bartosz Kempisty, Michał Nowicki, Magdalena Roszak

“…IntroductionStem cells derived from adipose tissue are gaining popularity in the field of regenerative medicine due to their adaptability and clinical potential. …”
Get full text

BRCA1 is involved in sustaining rapid antler growth possibly via balancing of the p53/endoplasmic reticulum stress signaling pathway by Qianqian Guo, Zhen Wang, Jiping Li, Chao Ma, Junjun Zheng, Hengxing Ba, Guokun Zhang, Chunyi Li

“…Understanding the mechanisms underlying the role played by BRCA1 in the process of antler regeneration is of great significance not only for regenerative medicine, but also for the understanding of cancer development.…”
Get full text

Harnessing macrophage-drug conjugates for allogeneic cell-based therapy of solid tumors via the TRAIN mechanism by Bartlomiej Taciak, Maciej Bialasek, Malgorzata Kubiak, Ilona Marszalek, Malgorzata Gorczak, Olha Osadchuk, Daria Kurpiel, Damian Strzemecki, Karolina Barwik, Marcin Skorzynski, Julia Nowakowska, Waldemar Lipiński, Łukasz Kiraga, Jan Brancewicz, Robert Klopfleisch, Łukasz Krzemiński, Emilia Gorka, Anna Smolarska, Irena Padzinska-Pruszynska, Małgorzata Siemińska, Jakub Guzek, Jan Kutner, Marlena Kisiala, Krzysztof Wozniak, Giacomo Parisi, Roberta Piacentini, Luca Cassetta, Lesley M. Forrester, Lubomir Bodnar, Tobias Weiss, Alberto Boffi, Paulina Kucharzewska, Tomasz P. Rygiel, Magdalena Krol

Get full text

Monkeypox-related knowledge and vaccination willingness among HIV-diagnosed and -suspected males: a cross-sectional survey in Changsha by Yingying Zhou, Jiemin Wang, Zhi Xie

Get full text

Copper Does Not Induce Tenogenic Differentiation but Promotes Migration and Increases Lysyl Oxidase Activity in Adipose-Derived Mesenchymal Stromal Cells by Marta Milewska, Anna Burdzińska, Katarzyna Zielniok, Katarzyna Siennicka, Sławomir Struzik, Piotr Zielenkiewicz, Leszek Pączek

Get full text

Highly efficient construction of monkey blastoid capsules from aged somatic cells by Junmo Wu, Tianao Shao, Zengli Tang, Gaojing Liu, Zhuoyao Li, Yuxi Shi, Yu Kang, Jiawei Zuo, Bo Zhao, Guangyu Hu, Jiaqi Liu, Weizhi Ji, Lei Zhang, Yuyu Niu

“…This advancement in the high-efficiency, scalable production of monkey blastoid capsules from reprogrammed aged somatic cells significantly enhances the study of embryonic development and holds promise for regenerative medicine.…”
Get full text

Anxiety, depression, and their association with unintentional injury risk among older adult populations in Guangxi, China: a cross-sectional study by Li Niu, Jie Zhang, Chun-liu Lu, Yong Zhang, Xin-xin Mo, Rong Xu, Hong-ye Luo

Get full text

Enhanced Generation of Human Induced Pluripotent Stem Cells from Peripheral Blood and Using Their Mesoderm Differentiation Ability to Regenerate Infarcted Myocardium by Ju-Young Kim, Han-Mo Yang, Joo-Eun Lee, Mika Jeon, Sang-Bum Bang, Jihye You, Joonoh Kim, Jaewon Lee, Jin Hur, Hyo-Soo Kim

“…These results suggest that our new method using CiMS cells has therapeutic potential in regenerative medicine using cell therapy.…”
Get full text

Stem Cell Therapy for Diseases of Livestock Animals: An In-Depth Review by Raghavendra B. Narasimha, Singireddy Shreya, Vijay Anand Jayabal, Vikas Yadav, Prasana Kumar Rath, Bidyut Prava Mishra, Sudhakar Kancharla, Prachetha Kolli, Gowtham Mandadapu, Sudarshan Kumar, Ashok Kumar Mohanty, Manoj Kumar Jena

“…This dual capability makes them valuable in the development of regenerative medicine. Current development in stem cell research has widened their application in cell therapy, drug discovery, reproductive cloning in animals, and cell models for various diseases. …”
Get full text

Prognosis of Elderly Japanese Patients Aged ≥80 Years Undergoing Hemodialysis by Shingo Hatakeyama, Hiromi Murasawa, Itsuto Hamano, Ayumu Kusaka, Takuma Narita, Masaaki Oikawa, Daisuke Noro, Kazuhisa Hagiwara, Hirofumi Ishimura, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, Hisao Saitoh, Tomihisa Funyu, Chikara Ohyama

Get full text

Apoptotic Vesicles Attenuate Acute Lung Injury via CD73-Mediated Inhibition of Platelet Activation and NETosis by Tan L, Zhang C, Kou X, Zhao L, Wu D, Li J, Yu C, Xu T, Gao L, Mao X, Zhao C

“…Lingping Tan,1,2,* Chi Zhang,1,2,* Xiaoxing Kou,1– 3 Lu Zhao,4 Di Wu,1– 3 Jinyu Li,1,2 Chuanying Yu,1,2 Tansi Xu,1,2 Li Gao,1,2 Xueli Mao,1– 3 Chuanjiang Zhao1,2 1Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, People’s Republic of China; 2Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, People’s Republic of China; 3South China Center of Craniofacial Stem Cell Research, Guangzhou, People’s Republic of China; 4Department of Orthodontics, Affiliated Stomatology Hospital of Guangzhou Medical University, Guangdong Engineering Research Center of Oral Restoration and Reconstruction, Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Guangzhou, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chuanjiang Zhao, Department of Periodontology, Hospital of Stomatology, Sun Yat-sen University, Guangzhou, Guangdong, 510055, People’s Republic of China, Email zhaochj@mail.sysu.edu.cn Xueli Mao, South China Center of Craniofacial Stem Cell Research, Guanghua School and Hospital of Stomatology, Sun Yat-sen University, Guangzhou, Guangdong, 510080, People’s Republic of China, Email maoxuel@mail.sysu.edu.cnIntroduction: Acute respiratory distress syndrome (ARDS) is a life-threatening type of acute lung injury (ALI) characterized by elevated mortality rates and long-term effects. …”
Get full text

Human striatal progenitor cells that contain inducible safeguards and overexpress BDNF rescue Huntington’s disease phenotypes by Danielle A. Simmons, Sridhar Selvaraj, Tingshuo Chen, Gloria Cao, Talita Souto Camelo, Tyne L.M. McHugh, Selena Gonzalez, Renata M. Martin, Juste Simanauskaite, Nobuko Uchida, Matthew H. Porteus, Frank M. Longo

Get full text

Crispant analysis in zebrafish as a tool for rapid functional screening of disease-causing genes for bone fragility by Sophie Debaenst, Tamara Jarayseh, Hanna De Saffel, Jan Willem Bek, Matthieu Boone, Ivan Josipovic, Pierre Kibleur, Ronald Y Kwon, Paul J Coucke, Andy Willaert

Get full text

Comparison between Intra-Articular Injection of Infrapatellar Fat Pad (IPFP) Cell Concentrates and IPFP-Mesenchymal Stem Cells (MSCs) for Cartilage Defect Repair of the Knee Joint... by Yaguang Han, Haobo Li, Rong Zhou, Jun Wu, Ziye Liu, Huan Wang, Jiahua Shao, Yi Chen, Jun Zhu, Qiwei Fu, Qirong Qian, Yiqin Zhou

“…Mesenchymal stem cells (MSCs) have emerged as a promising therapeutic method in regenerative medicine. Our previous research adopted a simple nonenzymatic strategy for the preparation of a new type of ready-to-use infrapatellar fat pad (IPFP) cell concentrates. …”
Get full text

Salivary metabolomics in oral cancer: A systematic review by Rita Antonelli, Giacomo Setti, Nathaniel S. Treister, Thelma A. Pertinhez, Elena Ferrari, Mariana Gallo, Ronell Bologna-Molina, Paolo Vescovi, Marco Meleti

Get full text

Gap junction intercellular communications regulates activation of SARM1 and protects against axonal degeneration by Wen Jie Zhu, Jun Liu, Wan Hua Li, Zhi Ying Zhao, Chongquan Huang, Jian Yuan Yang, Hon Cheung Lee, Yong Juan Zhao

Get full text

HLA DR Genome Editing with TALENs in Human iPSCs Produced Immune-Tolerant Dendritic Cells by Yoo-Wook Kwon, Hyo-Suk Ahn, Jin-Woo Lee, Han-Mo Yang, Hyun-Jai Cho, Seok Joong Kim, Shin-Hyae Lee, Heung-Mo Yang, Hyun-Duk Jang, Sung Joo Kim, Hyo-Soo Kim

“…Although human induced pluripotent stem cells (iPSCs) can serve as a universal cell source for regenerative medicine, the use of iPSCs in clinical applications is limited by prohibitive costs and prolonged generation time. …”
Get full text

Hepatobiliary organoid research: the progress and applications by Rui-Qi Zou, Rui-Qi Zou, Yu-Shi Dai, Yu-Shi Dai, Fei Liu, Fei Liu, Si-Qi Yang, Si-Qi Yang, Hai-Jie Hu, Hai-Jie Hu, Fu-Yu Li, Fu-Yu Li

“…We focus on applying hepatobiliary organoids in benign and malignant diseases of the liver and biliary tract, drug research, and regenerative medicine to provide valuable reference information for the application of hepatobiliary organoids. …”
Get full text

Evaluation of the Expression of Infection-Related Long Noncoding RNAs among COVID-19 Patients: A Case-Control Study by Zahra Firoozi, Elham Mohammadisoleimani, Farzaneh Bagheri, Atefeh Taheri, Babak Pezeshki, Mohammad Mehdi Naghizadeh, Abdolreza Daraei, Jalal Karimi, Yousef Gholampour, Yaser Mansoori, Zahra Montaseri

Get full text

Levying evidence of the impact of Triphala in the mildly constipated human colon microbiota by Elizabeth Goya-Jorge, Pauline Bondue, Irma Gonza, Samiha Boutaleb, Caroline Douny, Marie-Louise Scippo, Joël Pincemail, Patrice Chiap, Jeoffrey Christyn de Ribaucourt, Fabienne Crahay, Véronique Delcenserie

Get full text