Growth Hormone-Releasing Hormone and Its Analogues: Significance for MSCs-Mediated Angiogenesis by Xiangyang Xia, Quanwei Tao, Qunchao Ma, Huiqiang Chen, Jian’an Wang, Hong Yu

“…Mesenchymal stromal cells (MSCs) are promising candidates for regenerative medicine because of their multipotency, immune-privilege, and paracrine properties including the potential to promote angiogenesis. …”
Get full text

Live-cell metabolic analyzer protocol for measuring glucose and lactate metabolic changes in human cells by Kenji Miki, Mikako Yagi, Ko Igami, Hiroki Kittaka, Akito Tani, Natsuki Horiuchi, Satoshi Fukumoto, Koji Yoshimoto, Takeshi Uchiumi

“…Summary: Understanding metabolic conditions related to glycolysis dependence is crucial for developing new treatments in cancer and regenerative medicine. This protocol details a method for using the live-cell metabolic analyzer (LiCellMo) to measure continuous changes in glucose consumption and lactate production in cultured human cells. …”
Get full text

Improvement of the knock-in effciency in the genome of human induced pluripotent stem cells using the CRISPR/Cas9 system by М. М. Gridina

“…The ability to create patient-specifc pluripotent cells and their subsequent differentiation into any somatic cell type makes hiPS cells a valuable object for creating in vitro models of human diseases, screening drugs and a future source of cells for regenerative medicine. To realize entirely a potential of hiPScells, effective and precise methods for their genome editing are needed. …”
Get full text

Diabetes-Resistant NOR Mice Are More Severely Affected by Streptozotocin Compared to the Diabetes-Prone NOD Mice: Correlations with Liver and Kidney GLUT2 Expressions by S. Kahraman, C. Aydin, G. O. Elpek, E. Dirice, A. D. Sanlioglu

Get full text

Study on Compaction and Machinability of Silicon Nitride (Si3N4) Reinforced Copper Alloy Composite through P/M Route by T. Sathish, V. Mohanavel, Alagar Karthick, M. Arunkumar, M. Ravichandran, S. Rajkumar

Get full text

Locally Delivered Umbilical Cord Mesenchymal Stromal Cells Reduce Chronic Inflammation in Long-Term Nonhealing Wounds: A Randomized Study by Yulia Suzdaltseva, Sergey Zhidkih, Sergey L. Kiselev, Victor Stupin

“…Mesenchymal stromal cells (MSCs) have been considered a perspective tool for regenerative medicine because of their ability to change the expression and secretory profile under the influence of signals from the microenvironment to perform a regulatory function at the site of tissue damage. …”
Get full text

Gingival fibroblast suppress the osteogenesis process mediated by bone substitute materials via WNT/β-catenin signaling pathway in vitro and in vivo by Guanqi Liu, Jiahui Lin, Xiaoyan Chen, Runheng Liu

“…These findings highlight the importance of considering the cellular microenvironment in tissue engineering and regenerative medicine and suggest potential targets for modulating MMSCs behavior to enhance bone regeneration.…”
Get full text

The use of artificial intelligence in induced pluripotent stem cell-based technology over 10-year period: A systematic scoping review. by Quan Duy Vo, Yukihiro Saito, Toshihiro Ida, Kazufumi Nakamura, Shinsuke Yuasa

“…These enhancements are broadening the applications of iPSC technology in disease modelling, drug screening, and regenerative medicine. This review aims to explore the role of AI in the advancement of iPSC research.…”
Get full text

Expression of CD24 in Human Bone Marrow-Derived Mesenchymal Stromal Cells Is Regulated by TGFβ3 and Induces a Myofibroblast-Like Genotype by Luisa Marilena Schäck, Manuela Buettner, Alexander Wirth, Claudia Neunaber, Christian Krettek, Andrea Hoffmann, Sandra Noack

“…Human bone marrow-derived stromal cells (hBMSCs) derived from the adult organism hold great promise for diverse settings in regenerative medicine. Therefore a more complete understanding of hBMSC biology to fully exploit the cells’ potential for clinical settings is important. …”
Get full text

Developing human upper, lower, and deep lung airway models: Combining different scaffolds and developing complex co-cultures by Rasika S Murkar, Cornelia Wiese-Rischke, Tobias Weigel, Sascha Kopp, Heike Walles

Get full text

Protocol for quantifying muscle fiber size, number, and central nucleation of mouse skeletal muscle cross-sections using Myotally software by Pieter Both, Soochi Kim, Jengmin Kang, Marina Arjona, Daniel I. Benjamin, Christopher W. Nutter, Armon Goshayeshi, Thomas A. Rando

Get full text

Spinal Fusion in the Next Generation: Gene and Cell Therapy Approaches by Marta Barba, Claudia Cicione, Camilla Bernardini, Vincenzo Campana, Ernesto Pagano, Fabrizio Michetti, Giandomenico Logroscino, Wanda Lattanzi

“…The improved knowledge of both mesenchymal stem cell biology and osteogenic molecules allowed their use in regenerative medicine, representing attractive approaches to achieve bone regeneration also in spinal surgery applications. …”
Get full text

Novel Approach to Handling Microfiber-Rich Dye Effluent for Sustainable Water Conservation by R. Dharmaraj, Alagar Karthick, G. K. Arunvivek, S. Gopikumar, V. Mohanavel, M. Ravichandran, Murugesan Bharani

Get full text

Differential Proteomic Analysis Predicts Appropriate Applications for the Secretome of Adipose-Derived Mesenchymal Stem/Stromal Cells and Dermal Fibroblasts by Stefania Niada, Chiara Giannasi, Alice Gualerzi, Giuseppe Banfi, Anna Teresa Brini

“…The adult stem cell secretome is currently under investigation as an alternative to cell-based therapy in regenerative medicine, thanks to the remarkable translational opportunity and the advantages in terms of handling and safety. …”
Get full text

Prominosomes - a particular class of extracellular vesicles containing prominin-1/CD133? by Jana Karbanová, Kristina Thamm, Christine A. Fargeas, Ilker A. Deniz, Aurelio Lorico, Denis Corbeil

“…., as biomarkers in liquid biopsies or as native (or bioengineered) biological nanocarriers in tissue engineering, regenerative medicine and cancer therapy. Based on their cellular origin EVs can vary considerably in composition and diameter. …”
Get full text

A Combination of Coconut Fiber Suture and Tamarind Seed Gel with Dehydrated Human Amnion Membrane for Wound Surgery in Rats by Raghu Babu Pothireddy, Angeline Julius, Manu Thomas Mathai, Ganesh Lakshmanan, Beimnet Asfaw Hailemariam

Get full text

p38 MAPK Endogenous Inhibition Improves Neurological Deficits in Global Cerebral Ischemia/Reperfusion Mice by Kun Hou, Zhi-cheng Xiao, Hai-Long Dai

Get full text

Characterization of Neurogenic Potential of Dental Pulp Stem Cells Cultured in Xeno/Serum-Free Condition: In Vitro and In Vivo Assessment by Jieun Jung, Jong-Wan Kim, Ho-Jin Moon, Jin Young Hong, Jung Keun Hyun

Get full text

Effects of early local administration of high-dose bFGF on a recurrent laryngeal nerve injury model by Takao Goto, Rumi Ueha, Taku Sato, Tatsuya Yamasoba

“…Abstract Background Research on regenerative medicine using basic fibroblast growth factor (bFGF) has recently advanced in the field of laryngology. …”
Get full text

Effects of a narrative medicine program on empathic ability of dental students: a comparative study by Chufang Liao, Ting Zhong, Mengxue Xu, Yingzhi zhan, Xiangning Liu

Get full text