Allium cepa L. as a natural antioxidant: Its efficacy in combating heat stress-induced physiological alterations by Ayobami O. Sobanke, Afusat Aiyeola, Frances I. Okwuonu, Wuraola S. Nnaemeka, Jeremiah C. Ndubuisi, Franklin I. Udeoji, Jane N. Adiele

“…Hematological parameters, inflammatory markers, and lipid profiles were analyzed using blood samples obtained through heart puncture.The findings demonstrated that HS significantly lowered levels of hemoglobin (HB), red blood cell (RBC) counts, and antioxidant enzyme activity. …”
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Harnessing the power of proteins in modulation of miRNAs for targeting Iron deficiency Anemia: Opinion for future implications and strategies by Ray Wagiu Basrowi, Ray Wagiu Basrowi, Ray Wagiu Basrowi, Tonny Sundjaya, Tonny Sundjaya, Dessy Pratiwi, Nurlinah Amalia, Nurlinah Amalia, Nurlinah Amalia, Yosi Yohanes Putra Tandi, Muhammad Yasir Syafa’atulloh, Garuda Nusantara Putra Utomo, Muhammad Abdir Rahman Albarok, Fahrul Nurkolis

“…Proteins, acting as modulators of miRNA activity, present innovative pathways for intervention by influencing erythropoiesis at multiple stages, from stem cell proliferation to red blood cell maturation. Our synthesis highlights key molecular mechanisms: miR-15a suppresses erythropoiesis by inhibiting c-Myb, miR-24 impairs heme biosynthesis through ALK4 regulation, while miR-150 and miR-223 modulate critical hematopoietic pathways affecting cell differentiation and apoptosis. …”
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Malaria and Geohelminthiasis Coinfections in Expectant Women: Effect on Maternal Health and Birth Outcomes in a Malaria Endemic Region in Kenya by Wekesa Antony Wanyonyi, Chrispinus Siteti Mulambalah, David H. Mulama, Elizabeth Omukunda, Darwin Injete Siteti

“…Haemoglobin and eosinophils levels were determined by coulter counter while malaria parasitemia levels and red blood cell morphology were assessed by preparing and observing blood smears under the microscope. …”
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Unveiling the psychosocial and academic implications of living with sickle cell disease among undergraduates in a private university in Nigeria by Olumide T. Adeleke, Olufemi Folaranmi, Yetunde Olasinde, Larry Ayuba, Oludamola V. Adeleke, Modupe M. Ojo-Rufai, Efeturi Agelebe, Oyelola E. Adeoye, Aderemi T. Olabode, Dolapo E. Ajala, Titilola S. Akingbola

“…BackgroundSickle cell disease (SCD), a disease characterized with abnormal red blood cell morphology and is associated with diverse clinical manifestations and contribute to many psychosocial problems like social stigma, strained relationships and reduced self-esteem. …”
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An association between type A porcine endogenous retrovirus copy number and hematological parameters and gender in miniature pigs by R. B. Aitnazarov, S. V. Nikitin, G. V. Kontsevaya, M. I. Voevoda, N. S. Yudin

“…Reference values for eighteen blood parameters of miniature pigs were determined, including white blood cell count (WBC), red blood cell count (RBC), platelet count (PLT), absolute (LYM#) and relative (LYM%)  lymphocyte counts, absolute (MID#) and relative (MID%) monocyte, basophil and eosinophil counts, absolute (GRA#) and relative (GRA%) granulocyte counts, hematocrit (HCT) and thrombocrit (PCT), mean cell volume (MCV) and mean platelet volume (MPV). …”
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Adherence to Azathioprine/6-Mercaptopurine in Children and Adolescents with Inflammatory Bowel Diseases: A Multimethod Study by Mervat M. Alsous, Ahmed F. Hawwa, Cameron Imrie, Andras Szabo, Eman Alefishat, Rana Abu Farha, Mohammad Rwalah, Rob Horne, James C. McElnay

“…Medication adherence in 47 children (age range 3 to 17 years) with IBD in three centers in Northern Ireland and Jordan was assessed via subjective (parent and child versions of the Medication Adherence Report Scale (MARS) specific questionnaire) and objective methods, that is, high-performance liquid chromatography (HPLC) determination of the 6-mercaptopurine (6-MP) and azathioprine (AZA) metabolites in packed red blood cell samples taken during a clinic visit. Beliefs about prescribed medicines were also assessed in parents/guardians using the Beliefs about Medicines Questionnaire (BMQ). …”
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Characterization of serum metabolome and respiratory microbiota in children with influenza A virus infection by Xinyi Shi, Shenghao Hua, Zeyuan Chen, Weiyi Cao, Mengqing Xiao, Wenlong Pei, Zhe Cao, Zhan Zhang, Haibing Yang, Haibing Yang, Xuejun Shao, Yu Xia, Yu Xia

“…Compared with control group, IAV infection decreased the contents of platelet, white blood cell, lymphocyte, eosinophil, basophil, CD3+ T cells, CD4+ T cells, CD8+ T cells, and B cells, while increasing the number of red blood cell. Additionally, IAV infection increased serum concentrations of total protein, albumin and lipase, while decreasing the contents of calcium, triglyceride, total bilirubin, direct bilirubin, indirect bilirubin and gamma-glutamyltransferase. …”
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The COVID-19 pandemic and blood utilisation in South Africa by R Swanevelder, P-L Wessels, V J Louw, A Swarts, M Lennards, K van den Berg

“…This retrospective study reviews red blood cell (RBC) utilisation during a 4‐year period from 2019 to 2022 in the South African (SA) population, stratified by public and private healthcare sectors. …”
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An overview of hereditary spherocytosis and the curative effects of splenectomy by Kyril Turpaev, Elizaveta Bovt, Elizaveta Bovt, Soslan Shakhidzhanov, Soslan Shakhidzhanov, Elena Sinauridze, Elena Sinauridze, Nataliya Smetanina, Larisa Koleva, Larisa Koleva, Nikita Kushnir, Nikita Kushnir, Anna Suvorova, Fazoil Ataullakhanov, Fazoil Ataullakhanov, Fazoil Ataullakhanov

“…The causes of hereditary spherocytosis are mutations in genes that encode red blood cell (RBC) membrane and cytoskeletal proteins, including ankyrin-1, Band 3 (or AE1), α spectrin, β spectrin, and protein 4.2. …”
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Oakland score to identify low-risk patients with lower gastrointestinal bleeding performs well among emergency department patients by Daniel D. DiLena, Sean C. Bouvet, Madeline J. Somers, Maqdooda A. Merchant, Theodore R. Levin, Adina S. Rauchwerger, Dana R. Sax

“…The Oakland Score composite outcome includes re-bleeding, defined as additional blood transfusion requirements and/or a further decrease in hematocrit (Hct) >/= 20% after 24 h in clinical stability; red blood cell transfusion; therapeutic intervention to control bleeding, including surgery, mesenteric embolization, or endoscopic hemostasis; in-hospital death, all cause; and re-admission with further LGIB within 28 days. …”
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Th9 Cells in Peripheral Blood Increased in Patients with Immune-Related Pancytopenia by Qing Shao, Yangyang Wang, Zhaoyun Liu, Hui Liu, Yihao Wang, Yang Zhao, Lijuan Li, Rong Fu

“…They were negatively correlated with hemoglobin, red blood cell, white blood cell, and platelet counts and positively correlated with the percentage of CD19+B cells and CD5+CD19+/CD19+B cells, respectively. …”
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Influence of TMPRSS6 genotype on iron status parameters in stable COPD patients by Trtica Marko, Novaković Ivana, Dopsaj Violeta, Milenković Branislava, Janković Jelena, Dimić-Janjić Sanja, Dopuđa-Pantić Vesna, Martinović Jelena, Jovičić Snežana

“…Background: The SNP rs855791 has been linked to increased hepcidin levels, variations in serum iron, transferrin saturation and red blood cell indices. Our goal was to determine the prevalence of this polymorphism among COPD patients and to assess its impact on iron status parameters in patients with stable COPD. …”
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Co-administration of Hibiscus sabdariffa linn and Daflon-500® mitigates weight loss, hyperglycemia, hematological and oxidative changes in male rats with type-2 diabetes by Aishat Omobolanle Olatunji, Root Oluwapelumi Alegbe, Suleiman Folorunsho Ambali, Muftau Shittu, Ganiu Jimoh Akorede, Abdulfatai Aremu, Afisu Basiru, Jamila Abdulhamid Atata, Kolawole Yusuf Suleiman, Charles Amoto Shuaibu

“…Significantly higher packed cell volume, hemoglobin levels, red blood cell counts, lymphocytes, and mean corpuscular hemoglobin were observed in groups 5–7. …”
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Patient experience and burden of haemolytic disease of the foetus and newborn: a systematic review by P. Maurice, J. McCallion, M. Fitzgibbon, J. N. Barthelmes, W. Karmous, E. J. Hardy, S. A. Mitchell, C. R. Mitchell, J. Lee, W. Noel, Andras Borsi, J. M. Jouannic

“…Abstract Background Haemolytic disease of the foetus and newborn (HDFN) is an immune disorder driven by maternal alloimmunisation against foetal/newborn red blood cell antigens. HDFN can cause significant morbidity and mortality, with symptoms in the foetus ranging from mild anaemia to hydrops fetalis. …”
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Association of biochemical indicators with multimorbidity in 19,624 older adult individuals with chronic diseases: a study from Jindong District, Jinhua City, China by Qihuan Yao, Guozhong Chen

“…Among the biochemical indicators, hemoglobin (Hb) (OR = 1.46, 95%CI: 1.13–1.90), white blood cell count (WBC) (OR = 1.25, 95%CI: 1.02–1.54), red blood cell count (RBC) (OR = 1.36, 95%CI: 1.10–1.69), urinary protein (U-PRO) (OR = 1.10, 95%CI: 1.02–1.19), urinary glucose (U-GLU) (OR = 1.44, 95%CI: 1.23–1.67), alanine aminotransferase (ALT) (OR = 1.71, 95%CI: 1.39–2.10), aspartate aminotransferase (AST) (OR = 1.22, 95%CI: 1.05–1.41), creatinine (Cr) (OR = 1.28, 95%CI: 1.16–1.42), uric acid (UA) (OR = 1.36, 95%CI: 1.22–1.51), total cholesterol (TC) (OR = 1.76, 95%CI: 1.59–1.95), triglycerides (TG) (OR = 2.63, 95%CI: 2.46–2.82), low-density lipoprotein cholesterol (LDL-C) (OR = 1.84, 95%CI: 1.60–2.11), high-density lipoprotein cholesterol (HDL-C) (OR = 10.99, 95%CI: 8.12–14.90), and fasting blood glucose (FBG) (OR = 1.89, 95%CI: 1.74–2.05) are associated with the risk of multimorbidity of chronic diseases (p < 0.05). …”
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Respiratory Impairment after Early Red Cell Transfusion in Pediatric Patients with ALI/ARDS by Surender Rajasekaran, Dominic Sanfilippo, Allen Shoemaker, Scott Curtis, Sandra Zuiderveen, Akunne Ndika, Michael Stoiko, Nabil Hassan

“…In the first 48 hours of ventilating patients with acute lung injury (ALI)/acute respiratory distress syndrome (ARDS), a multipronged approach including packed red blood cell (PRBC) transfusion is undertaken to maintain oxygen delivery. …”
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Risk factors and machine learning prediction models for intrahepatic cholestasis of pregnancy by Yingchun Ren, Xiaoying Shan, Gengchao Ding, Ling Ai, Weiying Zhu, Ying Ding, Fuzhou Yu, Yun Chen, Beijiao Wu

“…Through univariable and lasso regression analysis, total bile acid, gamma-glutamyl transferase, multiple pregnancy, lymphocyte percentage, hematocrit, neutrophil percentage, prothrombin time, Aspartate aminotransferase, red blood cell count, lymphocyte count and platelet count were identified as risk factors of ICP. …”
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Comprehensive Sepsis Risk Prediction in Leukemia Using a Random Forest Model and Restricted Cubic Spline Analysis by Kou Y, Tian Y, Ha Y, Wang S, Sun X, Lv S, Luo B, Yang Y, Qin L

“…Key predictors of sepsis identified by SHAP analysis included C-reactive protein (CRP), procalcitonin (PCT), neutrophil count (Neut), lymphocyte count (Lymph), thrombin time (TT), red blood cell count (RBC), total bile acid (TBA), and systolic blood pressure (SBP). …”
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Optimization of temperature parameters for screening unexpected antibodies in Rh system by manual polybrene test by ZOU Xin, CHEN Minjie, MA Sifei, YANG Hongmei

“…[Methods] The reaction of IgG human anti-D antibody with different dilutions (undiluted, 1∶2, 1∶4, 1∶8, 1∶16, 1∶32，1∶64) with D antigen-positive red blood cells was detected by manual polybrene test (MPT). …”
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Efficacy and Safety of Recombinant Human Thrombopoietin (rhTPO) on Coagulation Function and Inflammatory Factors in the Treatment of Patients with Sepsis-Related Thrombocytopenia by Huijuan Wang MD, Dong Chen MD, Ming He MD

“…The Group R required significantly fewer red blood cell transfusions compared to the Group C and did not require Plt suspension ( P  < 0.05). …”
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