Reduced interhemispheric connectivity in traumatic brachial plexopathies after bionic reconstruction by Galia V Anguelova, Agnes Sturma, Oskar Aszmann, Mehmet S Yildirim, Anna Boesendorfer, Victor Schmidbauer, Karl-Heinz Nenning, Gregor Kasprian

“…The initial loss of white matter may be counteracted by increased function and grey matter recruitment, which seems necessary even after white matter recovery later with prosthesis use. …”
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Loneliness and Social Isolation with Risk of Incident Non-alcoholic Fatty Liver Disease, UK Biobank 2006 to 2022 by Ya Miao, Xiaoke Kong, Bin Zhao, Fang Fang, Jin Chai, Jiaqi Huang

“…Methods: In this large prospective cohort analysis with 405,073 participants of the UK Biobank, the status of loneliness and social isolation was assessed through self-administrated questionnaires at study recruitment. The primary endpoint of interest was incident NAFLD. …”
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Experiences and opinions of adults with type 1 diabetes on the android-based open-source closed-loop system in China: a qualitative study by Chaofan Wang, Daizhi Yang, Jinhua Yan, Ping Ling, Mengyun Lei, Ying Ni, Xiaodi Guo, Qingying Huang

“…Thematic analysis was adopted to analyse the transcribed text. Recruitment of interviewees would be halted when no new themes emerged. …”
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Lactic acid in the vaginal milieu modulates the Candida-host interaction by Diletta Rosati, Marisa Valentine, Mariolina Bruno, Arnab Pradhan, Axel Dietschmann, Martin Jaeger, Ian Leaves, Frank L. van de Veerdonk, Leo A.B. Joosten, Sumita Roy, Mark H. T. Stappers, Neil A.R. Gow, Bernhard Hube, Alistair J.P. Brown, Mark S. Gresnigt, Mihai G. Netea

“…This potentially contributes to the immune response dysregulation and neutrophil recruitment observed during recurrent VVC.…”
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International REACH forgiveness intervention: a multisite randomised controlled trial by Tyler J Vanderweele, Nicole Rodriguez, Richard G Cowden, Man Yee Ho, Everett L Worthington, Andrea Ortega Bechara, Zhuo Job Chen, Elly Yuliandari Gunatirin, Shaun Joynt, Viacheslav V Khalanskyi, Hennadii Korzhov, Ni Made Taganing Kurniati, Anastasiya Anastasiya Salnykova, Liudmyla Shtanko, Sergiy Tymchenko, Vitaliy L Voytenko, Anita Zulkaida, Maya B Mathur

“…Objectives To determine whether a brief self-directed forgiveness workbook intervention could alter forgiveness, depression symptoms, and anxiety symptoms.Design A multisite randomised waitlist-controlled trial was conducted among 4598 participants. Recruitment occurred from 11 February 2020 to 30 September 2021. …”
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Regulation of LPS-Induced Inflammatory Responses in Bovine Mammary Epithelial Cells via TLR4-Mediated NF-κB and MAPK Signaling Pathways by Lactoferrin by Kai Zhang, Ruizhen Zhang, Yuanyuan Zhang, Min Zhang, Hong Su, Feifei Zhao, Daqing Wang, Guifang Cao, Yong Zhang

“…Conversely, when LF is added post-inflammation, it appears to enhance cytokine expression, potentially promoting the recruitment of more cells or factors to resolve inflammation rapidly. …”
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Hypothermia regulates mitophagy and apoptosis via PINK1/Parkin-VDAC 3 signaling pathway during oxygen-glucose deprivation/recovery injury by Luying Zhang, Song Yang, Hao Cui, Chenchen Hang, Xingsheng Wang, Le An, Zhenyu Shan, Zhen Liang, Rui Shao, Ziren Tang

“…At 4 h after temperature intervention, hypothermia aggravated apoptosis through inhibiting Parkin recruitment to mitochondria and aggravating the release of Cyt C through open mPTP.…”
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Yorkshire Enhanced Stop Smoking (YESS) study: a protocol for a randomised controlled trial to evaluate the effect of adding a personalised smoking cessation intervention to a lung... by Richard D Neal, David Baldwin, Sarah Lewis, John Britton, Rachael L Murray, Qi Wu, Kate Brain, Samantha L Quaife, Matthew EJ Callister, Philip A J Crosbie, Harriet D Quinn-Scoggins, Grace M McCutchan, Alex Ashurst, Suzanne Rogerson, Rebecca Thorley

“…Eligible smokers will be randomised (1:1 in permuted blocks of random size up to size 6) to receive either an enhanced, personalised SC support package, including CT scan images, or continued standard best practice. Anticipated recruitment is 1040 smokers (January 2019–December 2020). …”
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Remote Lifestyle Intervention to Reduce Postpartum Weight Retention: Protocol for a Community-Engaged Hybrid Type I Effectiveness-Implementation Randomized Controlled Trial by Lindsay M Martin, Christine D McKinney, Lia Escobar Acosta, Janelle W Coughlin, Noelene K Jeffers, Alexandra Solano-Umaña, Kathryn A Carson, Nae-Yuh Wang, Wendy L Bennett, Kelly M Bower

“…ResultsThis study was funded in June 2021, and recruitment began in April 2023. As of November 2024, we enrolled 90 participants. …”
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Systematic multiomics analysis and in vitro experiments suggest that ITGA5 could serve as a promising therapeutic target for ccRCC by Xiangxian Che, Xi Tian, Zhenda Wang, Shuxuan Zhu, Shiqi Ye, Yue Wang, Yihan Chen, Yiyun Huang, Aihetaimujiang Anwaier, Peifeng Yao, Yijia Chen, Keting Wu, Yifei Liu, Wenhao Xu, Hailiang Zhang, Dingwei Ye

“…In vitro experiments and bioinformatical analysis identified ITGA5 function as predominantly cell proliferation, migration, angiogenesis, and macrophage recruitment. Further, we predicted immune infiltration and medication sensitivity regulation by ITGA5 and proposed a joint use of ITGA5 inhibitors and anti-angiogenetic drugs as a potential potent therapeutic strategy.…”
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Correlations between Traditional and Nontraditional Indicators of Adiposity, Inflammation, and Monocyte Subtypes in Patients with Stable Coronary Artery Disease by Silvia Bueno Garofallo, Vera Lucia Portal, Melissa Medeiros Markoski, Lucinara Dadda Dias, Alexandre Schaan de Quadrosa, Aline Marcadenti

“…Background. Recruitment of monocytes and low-grade inflammation process are both involved in obesity and in atherosclerosis. …”
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Interest, uptake, and feasibility trial of a real-life digital health intervention to improve lifestyle in Brazil by Raquel B De Boni, Jurema C Mota, Michael Duncan, Leonardo Linconl, Giovanna Lucieri Alonso Costa, Sofia Pimentel, Kamila P Sales, Fabiana Gaspar, Fernanda Adaes, Felipe B Schuch, Vicent Balanzá-Martinez, Flavio Kapczinski, Renato S Lima

“…and uptake were assessed via recruitment metrics. Acceptability and usability were measured using the Mobile App Rating Scale (MARS). …”
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Investigating a caregiver-assisted social skills group programme for primary and early high school-aged children with acquired brain injury or cerebral palsy: protocol for a pilot... by Koa Whittingham, Roslyn N Boyd, Rose Gilmore, Leanne Sakzewski, Nicola Hilton, Afroz Keramat, Bianca Thompson, Jacqui Barfoot, Christine T Moody

“…Thirty-two school-aged children (grades 3+; 8–13 years) with an ABI or CP and their caregiver(s) will be recruited and randomly assigned to either 12 week PEERS Plus or waitlist usual care. …”
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Development of an Alternative Protocol to Study Muscle Fatigue by Daniela A. Alambarrio, Benjamin K. Morris, R. Benjamin Davis, Emily B. Grabarczyk, Kari K. Turner, John M. Gonzalez

“…Muscle workload during EMS was measured with EMG using median power frequency (<b>MdPF</b>) and root mean square (<b>RMS</b>) as indicators of action potential velocity and muscle fiber recruitment. Ambulatory movement was induced and recorded for 20 min with a 4:4 duty cycle at 70 Hz. …”
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Mir-483-5p-mediated activating of IGF2/H19 enhancer up-regulates IGF2/H19 expression via chromatin loops to promote the malignant progression of hepatocellular carcinoma by Weiwei Chen, Chutian Wu, Yuting Li, Tonghua Wang, Miaoling Huang, Min Wang, Linjing Long, Yanfang Chen, Shufen Feng, Xuyou Liu, Shaohui Tang

“…Mechanistically, miR-483-5p increased recruitment of Ago1 and Ago2 at IGF2/H19 enhancer and then activated transcription of IGF2/H19 eRNA by RNA polymerase II and p300, which further induced chromatin loops formation between IGF2/H19 enhancer and IGF2/H19 promoters to activate IGF2/H19 promoters via IGF2/H19 eRNA-MED1-IGF2/H19 promoters complex in HCC cells. …”
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Convergent origin and accelerated evolution of vesicle-associated RhoGAP proteins in two unrelated parasitoid wasps by Colinet, Dominique, Cavigliasso, Fanny, Leobold, Matthieu, Pichon, Apolline, Urbach, Serge, Cazes, Dominique, Poullet, Marine, Belghazi, Maya, Volkoff, Anne-Nathalie, Drezen, Jean-Michel, Gatti, Jean-Luc, Poirié, Marylène

“…Here, we evidence the convergent recruitment and accelerated evolution of two multigene families of RhoGAPs presumably involved in virulence in two unrelated parasitoid wasp species, Leptopilina boulardi (Figitidae) and Venturia canescens (Icheumonidae). …”
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Comparative- and Cost-Effectiveness Research Determining the Optimal Intervention for Advancing Transgender Women With HIV to Full Viral Suppression (Text Me, Alexis!): Protocol fo... by Cathy J Reback, Thomas Blue, Ali Jalali, Raphael Landovitz, Michael J Li, Raymond P Mata, Danielle Ryan, Philip J Jeng, Sean M Murphy

“…is viral suppression and cost-effectiveness. ResultsRecruitment began on April 10, 2024, and the first participant was enrolled on April 11, 2024. …”
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Evidence for the Involvement of Lipid Rafts and Plasma Membrane Sphingolipid Hydrolases in Pseudomonas aeruginosa Infection of Cystic Fibrosis Bronchial Epithelial Cells by Domitilla Schiumarini, Nicoletta Loberto, Giulia Mancini, Rosaria Bassi, Paola Giussani, Elena Chiricozzi, Maura Samarani, Silvia Munari, Anna Tamanini, Giulio Cabrini, Giuseppe Lippi, Maria Cristina Dechecchi, Sandro Sonnino, Massimo Aureli

“…We also report for the first time that Pseudomonas aeruginosa infection causes a recruitment of plasma membrane-associated glycosphingolipid hydrolases into lipid rafts of CuFi-1-infected cells. …”
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Bone Defect Repair Using a Bone Substitute Supported by Mesenchymal Stem Cells Derived from the Umbilical Cord by Michal Kosinski, Anna Figiel-Dabrowska, Wioletta Lech, Lukasz Wieprzowski, Ryszard Strzalkowski, Damian Strzemecki, Lukasz Cheda, Jacek Lenart, Krystyna Domanska-Janik, Anna Sarnowska

“…Application of mesenchymal stem cells in the reconstruction surgery may have positive influence on tissue regeneration by secretion of angiogenic factors, recruitment of other MSCs, or differentiation into osteoblasts. …”
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A randomized controlled, trial on effects of mobile phone text messaging in combination with motivational interviewing versus standard infant feeding counselling on breastfeeding a... by Moleen Zunza, Lehana Thabane, Louise Kuhn, Christine Els, Carl Lombard, Mark F. Cotton, Taryn Young

“…Trial registration The trial was registered on ClinicalTrials.gov (NCT05063240) and Pan African Clinical Trial Registries (PACTR202110870407786) before recruitment of the first subject.…”
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