Psoriasis increases the risk of Sjögren’s syndrome: evidence from a propensity score-matched cohort study and transcriptomic analysis by Zijian Kang, Yu Du, Ran Cui, Qian Wang, Miao Chen, Yu-Hsun Wang, James Cheng‐Chung Wei, Sheng-Ming Dai

“…Transcriptomic analysis revealed potential shared pathogenesis of psoriasis and SS involving cellular proliferation, immune cell recruitment, cytokine secretion, and the interferon response to viral infections. …”
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Rationale and design of the HOVON 170 DLBCL-ANTICIPATE trial: preventing anthracycline-induced cardiac dysfunction with dexrazoxane by Marijke Linschoten, Jesse Geels, Erik van Werkhoven, Heleen Visser-Wisselaar, Martine E. D. Chamuleau, Arco J. Teske, Lourens Robbers, Simone Oerlemans, Heleen Crommelin, Marleen Breems-de Ridder, Astrid Schut, Folkert W. Asselbergs, Anna van Rhenen, on behalf of the HOVON 170 DLBCL – ANTICIPATE consortium

“…Results The medical research ethics committee approved the trial in May 2024. Recruitment has started in September 2024 and is expected to last for three years. …”
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Infiltration of Blood-Derived Macrophages Contributes to the Development of Diabetic Neuropathy by Jing-Jing Sun, Lin Tang, Xiao-Pei Zhao, Jun-Mei Xu, Yang Xiao, Hui Li

“…Studies have revealed that the recruitment of blood monocyte-derived macrophages (MDMs) to the spinal cord plays a pivotal role in different models of central nervous system injury. …”
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The effect of mindfulness-based counselling on the anxiety levels and childbirth satisfaction among primiparous pregnant women: a randomized controlled trial by Rozhin Feli, Sousan Heydarpour, Kamran Yazdanbakhsh, Fatemeh Heydarpour

“…The scores were then compared. Recruitment took place between June and December 2019, and 55 participants completed the study. …”
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Autism Spectrum Social Stories In Schools Trial (ASSSIST): study protocol for a feasibility randomised controlled trial analysing clinical and cost-effectiveness of Social Stories... by Dean McMillan, Victoria Allgar, Barry Wright, David Marshall, Shehzad Ali, Joy Adamson, Chris Williams, Elizabeth Littlewood, Dominic Trépel, Lisa Dyson, Hannah Ainsworth, Liz Cook, Lisa Hackney, Danielle Collingridge Moore, Rebecca Hargate, Anne McLaren, Jo Whitehead

“…Statistics will be calculated for recruitment rates, follow-up rates and attrition. Economic analysis will determine appropriate measures of generic health and resource use categories for cost-effectiveness analysis. …”
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Timely short-term specialised palliative home care for older people with frailty and their family: a mixed-methods pilot randomised controlled trial and process evaluation by Lieve Van den Block, Kim de Nooijer, Lara Pivodic, Peter Pype, Nele Van Den Noortgate, Rose Miranda, Kim Eecloo, Stefanie De Buyser, Aurelie Joos, Katlijn Van Mulders

“…Our secondary aim was to describe any preliminary effects of Frailty+.Design Pilot randomised controlled trial with process evaluation.Setting/Participants We aimed to recruit 50 adults (≥70 years) with Clinical Frailty Scale score 5–7, and complex care needs and their main family carer, if available, from two Belgian hospitals on discharge.Interventions Patients were randomised to the Frailty+ intervention alongside standard care or standard care alone.Outcome measures Implementation and trial feasibility were assessed through interviews, focus groups and quantitative data. …”
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Reducing antibiotic duration for acute otitis media: clinician, administrator, and parental insights to inform implementation of system-level interventions by Deborah J. Rinehart, Aiden Gilbert, Sonja O’Leary, Sophie E. Katz, Holly M. Frost

“…Participants: Purposeful sampling was used to recruit clinicians and administrators for qualitative interviews. …”
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Exercise-based cardiac rehabilitation for patients with atrial fibrillation receiving catheter ablation: protocol for a feasibility randomised controlled trial (RCT) with embedded... by Gregory Y H Lip, Helen Jones, Mark T Mills, Dhiraj Gupta, Lawrence Foweather, Benjamin JR Buckley, Charlotte Fitzhugh

“…Primary outcomes are recruitment rate, adherence to exercise-based cardiac rehabilitation and loss to follow-up. …”
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Unique pharmacological properties of etrasimod among S1P receptor modulators by Ibragim Gaidarov, H. Kiyomi Komori, Dariusz T. Stepniak, Karin Bruinsma, Huong Dang, Xiaohua Chen, Todd Anthony, Joel Gatlin, Lisa Karimi‐Naser, Anh‐Tuan Ton, Tim Indersmitten, Paul E. Miller, Andre Ghetti, Najah Abi‐Gerges, David Unett, Hussien Al‐Shamma, Christopher J. Rabbat, Catherine Crosby, John W. Adams

“…Using both heterologous expression systems and human umbilical vein endothelial cells that spontaneously express S1P1, we profiled key S1P1 downstream signaling pathways and found that etrasimod had similar potency to the other tested S1PR modulators in promoting β‐arrestin recruitment and S1P1 internalization. However, etrasimod was notably less potent than other S1PR modulators in assays measuring S1P1‐mediated G protein activation (GTPγS binding and cAMP inhibition). …”
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Mesenchymal Stromal Cells from Osteoarthritic Synovium Are a Distinct Population Compared to Their Bone-Marrow Counterparts regarding Surface Marker Distribution and Immunomodulati... by Sebastien Hagmann, Claudia Rimmele, Florin Bucur, Thomas Dreher, Felix Zeifang, Babak Moradi, Tobias Gotterbarm

“…Cocultures of both MSCs with CD4+ T-cells resulted in recruitment of CD45RA+ FoxP3+ regulatory T-cells. Upon stimulation, only SM-MSCs suppressed CD4+ T-cell proliferation, while both SM-MSCs and BM-MSCs modified cytokine profiles through suppressing IL-2 and TNF-α as well as increasing IL-6 secretion. …”
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The Exposure Assessment in Current Time Study: Implementation, Feasibility, and Acceptability of Real-Time Data Collection in a Community Cohort of Illicit Drug Users by Gregory D. Kirk, Beth S. Linas, Ryan P. Westergaard, Damani Piggott, Robert C. Bollinger, Larry W. Chang, Andrew Genz

“…Participants. Participants were recruited from an ongoing community-cohort of current or former injection drug users. …”
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Anti-Inflammatory Effects of Ellagic Acid on Acute Lung Injury Induced by Acid in Mice by Daniely Cornélio Favarin, Maxelle Martins Teixeira, Ednéia Lemos de Andrade, Claudiney de Freitas Alves, Javier Emilio Lazo Chica, Carlos Artério Sorgi, Lúcia Helena Faccioli, Alexandre Paula Rogerio

“…In both preventive and therapeutic treatments, ellagic acid reduced the vascular permeability changes and neutrophil recruitment to the bronchoalveolar lavage fluid (BALF) and to lung compared to the vehicle. …”
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Linear growth rate of vyrezub (Rutilus frisii Nordmann, 1840) in the Dnister River basin by V. Gurbyk, A. Mruk, L. Strembitskyi, A. Kucheruk

“…To achieve high rates of recruitment of natural localities with vyrezub (Rutilus frisii Nordmann, 1840), it is a priority to increase the size characteristics of fish seeds under aquaculture conditions, which is interdependent on the linear growth rate of different age groups of vyrezub. …”
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Inhibition of the Ubiquitin-Activating Enzyme UBA1 Suppresses Diet-Induced Atherosclerosis in Apolipoprotein E-Knockout Mice by Jiawei Liao, Xiaolei Yang, Qiuyue Lin, Shuang Liu, Yunpeng Xie, Yunlong Xia, Hui-Hua Li

“…PYR-41 did not alter circulating immune cells determined by flow cytometry but significantly reduced aortic mRNA levels of cytokines related to monocyte recruitment (Mcp-1, Vcam-1, and Icam-1) and macrophage proinflammatory responses (Il-1β and Il-6). …”
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Microbial phenolic metabolites are associated with better frontal lobe cognition by Inés Domínguez-López, Isabella Parilli-Moser, Anna Vallverdú-Queralt, Anna Tresserra-Rimbau, Cinta Valls-Pedret, Zenaida Vázquez-Ruiz, Olga Castañer, Ramon Estruch, Emili Ros, Rosa M. Lamuela-Raventós

“…This cross-sectional analysis was performed with 200 participants of the PREDIMED trial (Barcelona-Clinic recruitment center). A novel method based on liquid chromatography coupled to mass spectrometry was used to identify urinary MPM (protocatechuic acid, enterodiol glucuronide, enterolactone glucuronide, urolithin B glucuronide, and vanillic acid glucuronide), and cognitive function was evaluated with neuropsychological tests. …”
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Characterisation of coastal reef fish assemblages across an estuarine-urbanisation gradient using underwater visual census and environmental DNA metabarcoding by Yu-De Pei, Joseph Heard, Wenqian Xu, Shara K.K. Leung, Charmaine C.M. Yung, Alex S.J. Wyatt

“…Seasonal variations in fish generic richness and assemblage structure were observed using both approaches, taken to reflect changes in fish behaviour, physiology, and naturally occurring events (i.e., spawning and recruitment) between seasons. A notable, consistent reduction in fish richness from eDNA in the semi-enclosed Port Shelter might reflect limited exchange of water and genetic materials. …”
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The systemic oxidative stress index predicts clinical outcomes of esophageal squamous cell carcinoma receiving neoadjuvant immunochemotherapy by Jifeng Feng, Jifeng Feng, Liang Wang, Xun Yang, Qixun Chen, Qixun Chen

“…The current research aims to explore the prognostic role of systemic oxidative stress index (SOSI) on ESCC receiving neoadjuvant immunochemotherapy (nICT).MethodsRetrospective recruitment was used to identify 224 nICT-treated ESCC patients. …”
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Assessment of Geriatric Problems and Risk Factors for Delirium in Surgical Medicine: Protocol for Multidisciplinary Prospective Clinical Study by Henriette Louise Möllmann, Eman Alhammadi, Soufian Boulghoudan, Julian Kuhlmann, Anica Mevissen, Philipp Olbrich, Louisa Rahm, Helmut Frohnhofen

“…In addition, a telephone follow-up will be performed 3, 6, and 12 months after discharge. ResultsRecruitment started in August 2022, with 421 patients already recruited at the time of submission. …”
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Adult education and training for the development of problem-solving skills by I. A. Korshunov, S. V. Lubnikov, N. N. Shirkova

“…This article might be of interest for the specialists in sphere of adult education and lifelong learning, HR-specialists and small and medium-sized enterprise managers in order to improve the efficiency of the recruitment process and to adopt more efficient employer-provided training systems.…”
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Risperidone versus placebo for aggression following traumatic brain injury: a feasibility randomised controlled trial by Paul Bassett, Tim Weaver, Shoumitro Deb, Mike Crawford, David Sharp, Lina Aimola, Verity Leeson, Mayur Bodani, Lucia Li

“…Data from the process evaluation suggest that existence of specialised TBI follow-up clinics, availability of a dedicated database of TBI patients’ clinical details, simple study procedures and regular support to participants would enhance recruitment and retention in the trial. Feedback from participants showed that once in the study, they did not find the trial procedure onerous.Conclusions It was not feasible to conduct a successful randomised trial of risperidone versus placebo for post-TBI aggression using the methods we deployed in this study. …”
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