Synergistic Stimulation with Different TLR7 Ligands Modulates Gene Expression Patterns in the Human Plasmacytoid Dendritic Cell Line CAL-1 by Tobias Hilbert, Folkert Steinhagen, Christina Weisheit, Georg Baumgarten, Andreas Hoeft, Sven Klaschik

“…This effect was due to a stronger stimulation of already regulated genes (by monostimulation) as well as to recruitment of thus far unregulated genes. Top scoring canonical pathways referred to immune-related processes. …”
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Nurture-U student mental health longitudinal survey: a study protocol by Kate E Saunders, Samuel R Chamberlain, Jemima Dooley, Edward R Watkins, Liz Forty, Sarah Rees, Anne C Duffy, Anthony Quinn, Ellen Marshall, Lucy Dorey, Kevin A Matlock, Alexandra Newbold, Lucy J Robinson

“…The study will collect data at the start and completion of each academic year, using validated measures to assess well-being, mental health symptoms, lifestyle factors and access to support. Recruitment will target all students, with an emphasis on first-year students, to track their mental health trajectory from university entry through subsequent years.Ethics and dissemination Ethical approval has been obtained from relevant committees at each participating university. …”
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3-Acetyldeoxynivalenol induces pyroptosis in leydig cells via METTL3-mediated N6-methyladenosine modification of NLRP3 by Yangyun Wang, Chaoliang Shi, Wei Jiao, Xiaoxiang Wan

“…Notably, IGF2BP1 was found to inhibit the recruitment of the BTG2/CCR4-NOT complex by competitively binding to PABPC1, thereby preventing the deadenylation of NLRP3 mRNA and maintaining its expression. …”
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An indole alkaloid from a tribal folklore inhibits immediate early event in HSV-2 infected cells with therapeutic efficacy in vaginally infected mice. by Paromita Bag, Durbadal Ojha, Hemanta Mukherjee, Umesh Chandra Halder, Supriya Mondal, Nidhi S Chandra, Suman Nandi, Ashoke Sharon, Mamta Chawla Sarkar, Sekhar Chakrabarti, Debprasad Chattopadhyay

“…Moreover, Western blot and qRT-PCR assays demonstrated that HM suppressed viral IE gene expression, while the EMSA and co-immunoprecipitation studies showed that HM interfered with the recruitment of LSD-1 by HCF-1. The in vivo studies revealed that HM at its virucidal concentration was nontoxic and reduced virus yield in the brain of HSV-2 infected mice in a concentration dependent manner, compared to vaginal tissues. …”
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On Job Training and Employee Productivity in Banking Institutions in Uganda: A Case Study of Centenary Bank Kabale Branch. by Nakero, Sarah

“…Areas suggested for further research included; the role of motivation and employee performance in the selected financial Institutions in Uganda and the relationship between the recruitment and deployment of female employee and access to quality financial services.…”
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Effect of Folic Acid Supplementation in Pregnancy on Preeclampsia: The Folic Acid Clinical Trial Study by Shi Wu Wen, Josee Champagne, Ruth Rennicks White, Doug Coyle, William Fraser, Graeme Smith, Dean Fergusson, Mark C. Walker

“…To date we have twenty participating Canadian centers, of which eighteen are actively recruiting, and seven participating Australian centers, of which two are actively recruiting. …”
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Validation of a tele-robotic ultrasound system for abdomen and thyroid gland explorations: a comparison with standard ultrasound by Andreu Antolin, Nuria Roson, Marina Planes, Mar Castillo, Anna Alberti, Manuel Escobar

“…Results 64 participants (23 male, 41 female) were consecutively included during the recruitment period, for a total of 51 abdominal and 37 thyroid gland US studies. …”
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Lipoxin Inhibits Fungal Uptake by Macrophages and Reduces the Severity of Acute Pulmonary Infection Caused by Paracoccidioides brasiliensis by Laura R. R. Ribeiro, Flávio V. Loures, Eliseu F. de Araújo, Cláudia Feriotti, Tânia A. Costa, Carlos Henrique Serezani, Sonia Jancar, Vera L. G. Calich

“…In susceptible mice, MLT treatment led to reduced influx of PMN leukocytes, increased recruitment of monocytes, predominant synthesis of anti-inflammatory cytokines, and augmented expression of 5- and 15-lipoxygenase mRNA, suggesting a prevalent LXA4 activity. …”
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Main aspects of occupation policy of labour obligations in Lithuania in the years 1941-1944 by Justinas Braslauskas

“… After generalization of the thoughts stated in the article, the following conclusions were made: 1. Recruitment of the local inhabitants for labour in Lithuania and outside its borders - in Germany - was managed by the entire system of German and local municipal bodies. …”
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Strength training for osteoporosis prevention during early menopause (STOP-EM): a pilot study protocol for a single centre randomised waitlisted control trial in Canada by Leigh Gabel, Lauren A Burt, Christina J Alexander, Leah Kaluta, Patrick W Whitman, Emma O Billington

“…The primary outcomes are recruitment, retention and adherence to the exercise intervention. …”
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Risk Factors for Excessive Gestational Weight Gain in a Healthy, Nulliparous Cohort by Antonia Restall, Rennae S. Taylor, John M. D. Thompson, Deralie Flower, Gustaaf A. Dekker, Louise C. Kenny, Lucilla Poston, Lesley M. E. McCowan

“…Other factors independently associated with excessive GWG included recruitment in Ireland, younger maternal age, increasing maternal birthweight, cessation of smoking by 14–16 weeks, increased nightly sleep duration, high seafood diet, recent immigrant, limiting behaviour, and decreasing exercise by 14–16 weeks. …”
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How do families access holiday activities and food programmes and other support? Learnings from the Borough of Southwark holiday activities and food club’s evaluation by Lorraine McSweeney, Anita Sewornu, Louis Goffe, Bronia Arnott, Ashley Adamson

“…Semi-structured interviews were conducted with parents/carers of HAF eligible children and semi-structured interviews/focus groups were held with children and young people (CYP) attending a HAF club. Recruitment was through the clubs. The transcripts were coded by two independent researchers and thematic analysis applied.ResultsNine parent/carers and two young people took part in an interview. …”
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Reconstitution of human DNA licensing and the structural and functional analysis of key intermediates by Jennifer N. Wells, Lucy V. Edwardes, Vera Leber, Shenaz Allyjaun, Matthew Peach, Joshua Tomkins, Antonia Kefala-Stavridi, Sarah V. Faull, Ricardo Aramayo, Carolina M. Pestana, Lepakshi Ranjha, Christian Speck

“…We determined the hOCCM structure, which showed that hORC-hCDC6 recruits hMCM2-7 via five hMCM winged-helix domains. …”
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Research Progress on the Role of Inflammasomes in Kidney Disease by Kun Chi, Xiaodong Geng, Chao Liu, GuangYan Cai, Quan Hong

“…Inflammasomes are multimeric complexes composed of cytoplasmic sensors, apoptosis-associated speck-like protein containing a caspase activation and recruitment domain (ASC or PYCARD), and procaspase-1 and play roles in regulating caspase-dependent inflammation and cell death. …”
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Efficacy and Safety of Murivenna Anal Infiltration Compared to Diltiazem Topical Application in Chronic Anal Fissure: Protocol for a Prospective, Randomized, Open-Label Clinical Tr... by Pratap Shankar KM, Indu Puthan Purayil, Palengara Binitha, Amit Kumar Rai, Sophia Jameela, Azeem Ahmad, Chandra Sekhara Rao Bhogavalli, Narayanam Srikanth, Rabinarayan Acharya

“…ResultsThe project was funded in July 2023, and the study period is 24 months. Participant recruitment started in December 2023. As of August 2024, we have enrolled 50 participants. …”
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Choosing a starting professional trajectory: job-education mismatch effect by A. D. Melnik, A. E. Sudakova, N. L. Antonova

“…This engagement increases interest in the cultivation and early recruitment of proactive students for the development of high-tech industries and intellectual services.…”
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Clinical Research Network: JHCRN Infrastructure and Lessons Learned by Rahul Kashyap, Gayane Yenokyan, Robert Joyner, Melissa Gerstenhaber, Mary Alderfer, Erika Siegrist, Joan Moore, Channing J. Paller, Hanan Aboumatar, James J. Potter, Stanley Watkins Jr, John E. Niederhuber, Daniel E. Ford, Adrian Dobs

“…The impact of protocol complexity often results in inadequate recruitment and insufficient sample sizes, which challenges validity and generalizability. …”
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Effectiveness of the User-Centered “Healthcare CEO” App for Patients With Type 1 Diabetes Transitioning From Adolescence to Early Adulthood: Protocol for a Randomized Controlled Tr... by Yueh-Tao Chiang, Hsing-Yi Yu, Pei-Kwei Tsay, Chi-Wen Chen, Chi-Wen Chang, Chien-Lung Hsu, Fu-Sung Lo, Philip Moons

“…It was originally scheduled from August 2020 to July 2022 but was interrupted by the COVID-19 pandemic after enrolling 38 participants, with preliminary results anticipated for publication by November 2024. Recruitment resumed in August 2023, with findings expected to be finalized by July 2025. …”
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A Mobile App–Based Gratitude Intervention’s Effect on Mental Well-Being in University Students: Randomized Controlled Trial by Chloë Fuller, Silvia Marin-Dragu, Ravishankar Subramani Iyer, Sandra Melanie Meier

“…MethodsWe used a randomized experimental design to test our objective. Participants were recruited undergraduate students from a web-based university study recruitment system. …”
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The effect of educational intervention based on the mobile application on women’s knowledge, attitude, and practice on microplastics and health: study protocol for a randomized con... by Zahra Seifi, Fatemeh Zarei, Fazlollah Ahmadi

“…The enrolment of participants began on 2024–09-22. The recruitment is estimated to be completed by 2024–11-21. …”
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