Randomised controlled trial to investigate the effectiveness of local oestrogen treatment in postmenopausal women undergoing pelvic organ prolapse surgery (LOTUS): a pilot study to... by Jane Daniels, Lee Middleton, Tina Sara Verghese, Versha Cheed, Lisa Leighton, Pallavi Manish Latthe

“…Oestrogen treatment (oestradiol hemihydrate 10 μg vaginal pessaries) commenced 6 weeks prior to surgery (once daily for 2 weeks, twice weekly for 4 weeks) and twice weekly for 26 weeks from 6 weeks postsurgery.Outcome measures The main outcomes were assessment of eligibility and recruitment rates along with compliance and data completion. …”
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Current attitudes to testicular prosthesis insertion during radical orchidectomy—An international perspective by Anthony Emmanuel, Abi Kanthabalan, Cameron Alexander, Nikita Bhatt, Vinson Chan, Odunayo Kalejaiye, Krishna Narahari, Veeru Kasivisvanathan, Majed Shabbir

“…Methods An international online survey of urologists who perform radical orchidectomy for testicular cancer was developed. The recruitment process used social media and the emailing lists of national urological societies. …”
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Improve the quality of end-of-life in cancer patients using social representations of nutrition by Lucia Inmaculada Llinares-Insa, Encarna Chisbert-Alapont, María Amparo Benedito-Monleón, Pilar González-Navarro

“…Furthermore, given that food has an important cultural component as important as it is nutrition, the sociocultural influence on the social representation of nutrition will also be analyzed.MethodsThe study design was qualitative and cross-sectional with a recruitment period lasting 18 months. After the informed consent, a sample of advanced cancer patients (N=57) and their caregivers (N=57) were interviewed individually. …”
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Older, vulnerable patient view: a pilot and feasibility study of the patient measure of safety (PMOS) with patients in Australia by Jeffrey Braithwaite, Natalie Taylor, Rebecca Lawton, Robyn Clay-Williams, Emily Hogden, Zhicheng Li

“…The second phase tested the revised measure to establish the internal consistency reliability of the revised subscales, and piloted the recruitment and administration processes to ensure feasibility of the PMOS for use in DUQuA.Results Of the 43 questions in the PMOS, 13 (30%) were amended based on issues patients highlighted for improvement in phase 1. …”
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An assessment of South African policy and strategic framework for the development of a sufficient, equitably distributed and well-performing health workforce for the implementation... by S V Mokoena, P Naidoo

“…This requires leadership, governance and stewardship acumen to put in place policies, practices and resources that are essential to recruit and retain human resources for health. Objective. …”
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Transformation of the Personnel Policy of Russian Universities Participating in Project 5-100: The Case of National Research Nuclear University Mephi by E. A. Drugova, I. B. Pleshkevich, T. V. Klimova

“…The study showed that the HRM system at MEPhI was significantly transformed under the influence of the Project 5-100: the personnel policy was formalized in high-level strategic documents; the processes of recruitment and selection of foreign employees have been rebuilt; the considerable increase in the number of foreign employees was reached; global partners began to play an important role; a comfortable environment for the implementation of initiatives was created and opportunities for professional development were provided. …”
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Causal associations between socioeconomic status and prostate cancer using two-sample Mendelian randomization study by Zhenxing Wang, Chunyan Wang, Xing Gou, Liang Pei, Xiaoyuan Qiao

“…Through two-sample Mendelian randomization (MR), this research seeks to assess the causal links between 4 genetically predicted SES indicators—average total household income before tax, the Townsend deprivation index at recruitment, unemployed status and college or university degree in the household—and PCa. …”
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What are the problems and suggestions related to cancer health education in Sichuan, China? A qualitative study of community health workers (CHWs) by Zhonghua Yang, Qingqing Wang, Fang Yi, Linglin Zhang, Yuting Li, Lilou Rong, Shaoping Wan

“…CHWs proposed some suggestions to improve the accessibility and acceptability of cancer health education, including combining online and offline education, health education after screening, cancer plus others, health education in the workplace, and volunteer recruitment. Conclusions Both the problems and suggestions described in this study may provide evidence for cancer health education and policy-making related to cancer prevention and control in China.…”
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Invariant Spatial Pattern Across Mediterranean Scrublands in the Iberian Pear (Pyrus bourgaeana) by Brayan Morera, Pedro J. Garrote, Thorsten Wiegand, Daniel Ayllón, Jose M. Fedriani

“…We tested two hypotheses: (i) because the clumped defecation behavior of some dispersers can lead to local tree aggregation, and because denser groups of fruiting trees can limit seed dispersal by attracting frugivores to specific sites, we expected a consistent small‐scale aggregation pattern across all populations; and (ii) because ungulates reduce recruitment by preying on seeds and seedlings, we hypothesize that ungulate activity will show negative relationships with tree density and level of aggregation. …”
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Cytosolic DNA composition is determined by genomic instability mechanism and regulates dendritic cell-mediated anti-tumor immunity by Shayla R. Mosley, Angie Chen, David N.W. Doell, Siwon Choi, Courtney Mowat, Felix Meier-Stephenson, Vanessa Meier-Stephenson, Kristi Baker

“…Previous investigations identified the cytosolic DNA (cyDNA) sensor STING as necessary for chemokine-mediated T cell recruitment in MSI CRCs. Here, we find that cyDNA from MSI CRC cells is inherently more capable of inducing STING activation and improves cytotoxic T cell activation by dendritic cells (DCs). …”
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Feasibility of home-based urine collection in children under 5 years in the ORIGINS birth cohort study: mixed method protocol and sample completion results by Courtney D. A. Kidd, Najma A. Moumin, Andrea MacRae, Tim J. Green, Desiree T. Silva, Susan L. Prescott, Nina D’Vaz

“…Methods The ORIGINS Project is an ongoing birth cohort investigating early life influences on child health outcomes in Perth, Australia. Recruitment began in 2017, with 3713 children consented by December 2022. …”
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Personnel training for the security and defense sector as a prerequisite for ensuring the national security of Ukraine by V. V. Sokurenko

“…It has been argued that to ensure quality personnel training for the security and defense sector, it is important to form a quality system of recruitment and staffing of security and defense forces with professional staff, updating approaches to the selection procedure (both professional and psychological, moral) of candidates for service in the security and defense sector; improving the quality of training of scientific personnel who have special knowledge, skills, abilities and methods necessary to solve problems related to the functioning of the security and defense sector; strengthening practical training, in particular conducting trainings focused on providing practical skills and abilities to resolve conflicts without the use of special tools and weapons; improving the quality and intensity of joint training of defense forces to conduct strategic actions.…”
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Sphingosine-1-Phosphate Signaling in Immune Cells and Inflammation: Roles and Therapeutic Potential by Masayo Aoki, Hiroaki Aoki, Rajesh Ramanathan, Nitai C. Hait, Kazuaki Takabe

“…In this review, we summarize previous findings and new discoveries about the importance of S1P and S1PR signaling in the recruitment of immune cells and lymphocyte retention in inflamed tissues. …”
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Early transcriptomic changes at the skin interface during Powassan virus transmission by Ixodes scapularis ticks by Dakota N. Paine, Dakota N. Paine, Meghan Hermance, Saravanan Thangamani, Saravanan Thangamani, Saravanan Thangamani

“…Although early POWV transmission induces minimal changes in the local environment, a pronounced shift toward a proinflammatory state is observed 6 h after tick attachment, characterized by neutrophil recruitment and interleukin signaling.DiscussionThese transcriptomic data elucidate the dynamic changes at the tick bite site, transitioning from changes that assist blood meal acquisition to a proinflammatory phase that may facilitate viral dissemination.…”
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From pain to meningitis: bacteria hijack nociceptors to promote meningitis by Huazhen Liu, Xingxing Kong, Yuqin Zeng, Jinyun Chen, Zhanpeng Chen, Lanlan Liu, Quan Ma, Xuhui Liu, Xuhui Liu, Shuihua Lu

“…These interactions suppress immune defenses by inhibiting macrophage activity and neutrophil recruitment, thus facilitating bacterial survival and invasion of the CNS. …”
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Gender bias in urology: The role of gender in selecting urology as a medical specialty by Mansour Alnazari, Abdullah K. Aljohani, Emad S. Rajih, Abdulaziz Bakhsh, Ghadi S. Alghamdi, Faris S. Sebaa, Ali A. Alraddadi, Adel Moalwi

“…Although there have been advances, urology has remained overwhelmingly male-dominant, with slow growth in female recruitment. Objectives: The study aimed to assess whether the gender influences selection of medical specialty, especially gender bias in urology. …”
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Brain Hemodynamic Intermediate Phenotype Links Vitamin B12 to Cognitive Profile of Healthy and Mild Cognitive Impaired Subjects by Luca Cecchetti, Giada Lettieri, Giacomo Handjaras, Andrea Leo, Emiliano Ricciardi, Pietro Pietrini, Silvia Pellegrini, The Train the Brain Consortium

“…We found that the hemodynamic activity of the right dorsal anterior cingulate cortex was positively associated (p value<0.05 cluster corrected) with vitamin B12 concentrations, suggesting that elders with higher B12 levels had a more pronounced recruitment of this salience network region. Crucially, the activity of this area significantly predicted subjects’ visual search and attention abilities (p value=0.0023), whereas B12 levels per se failed to do so. …”
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Opening the digital doorway to sexual healthcare: Recommendations from a behaviour change wheel analysis of barriers and facilitators to seeking online sexual health information an... by Julie McLeod, Claudia S Estcourt, Jennifer MacDonald, Jo Gibbs, Melvina Woode Owusu, Fiona Mapp, Nuria Gallego Marquez, Amelia McInnes-Dean, John M Saunders, Ann Blandford, Paul Flowers

“…<h4>Methods</h4>The PROGRESSPlus framework guided purposive recruitment (15.10.21-18.03.22) of 35 UK participants from diverse backgrounds, including 51% from the most deprived areas and 26% from minoritised ethnic groups. …”
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The Immunosuppressant Fingolimod (FTY720) for the Treatment of Mechanical Force-Induced Abnormal Scars by Masayo Aoki, Akatsuki Kondo, Noriko Matsunaga, Azusa Honda, Yuri Okubo, Kazuaki Takabe, Rei Ogawa

“…The lipid mediator sphingosine-1-phosphate (S1P) is important in inflammatory cell recruitment and angiogenesis. Fingolimod (FTY720) is an analog of S1P and thus functionally antagonizes S1P receptors and inhibits the enzyme that produces S1P. …”
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Poly-γ-Glutamic Acid Attenuates Angiogenesis and Inflammation in Experimental Colitis by Munkhtugs Davaatseren, Jin-Taek Hwang, Jae Ho Park, Myung-Sunny Kim, Shuaiyu Wang, Mi Jeong Sung

“…In addition, γ-PGA treatment led to reduced recruitment of leukocytes to the inflamed colon. Therefore, our results indicate that γ-PGA has potential application in conditions marked by inflammatory-driven angiogenesis and mucosal inflammation.…”
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