Long-term exposure to PM2.5 and its constituents and visual impairment in schoolchildren: A population-based survey in Guangdong province, China by Jia-Hui Li, Hui-Xian Zeng, Jing Wei, Qi-Zhen Wu, Shuang-Jian Qin, Qing-Guo Zeng, Bin Zhao, Guang-Hui Dong, Ji-Chuan Shen, Xiao-Wen Zeng

“…Methods: We conducted a large cross-sectional population-based study to recruit 59,054 schoolchildren from four cities in Guangdong province, China, and used the ChinaHighAirPollutants (CHAP) dataset to estimate 3-year average concentrations of PM2.5 and its constituents (black carbon (BC), organic matter (OM), nitrate (NO3–), sulfate (SO42−) and ammonium (NH4+)) based on individuals’ home addresses. …”
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Development a glycosylated extracellular vesicle-derived miRNA Signature for early detection of esophageal squamous cell carcinoma by Jianlin Chen, Yue Zheng, Zhen Wang, Qi Gao, Kun Hao, Xiongfeng Chen, Nantian Ke, Xiang Lv, Jiamiao Weng, Yuhong Zhong, Zhixin Huang, Miao Fu, Lilan Zhao, Fan Lin, Hui Mi, Haijun Tang, Chundong Yu, Yi Huang

“…Methods A total of 371 ESCC and 303 healthy controls (HCs) were recruited in this multi-stage, multicentre case-control study. …”
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Characteristics and contributing factors of adverse drug reactions: an analytical study of patients with tuberculosis receiving treatment under the National TB Program of India [ve... by Jay Patel, Priya Bhavsar, Harsh Shah, Sandul Yasobant, Deepak Saxena, Anish Sinha, Somen Saha, Yogesh Patel

“…A total of 593 reported TB patients were recruited with an adjusted unified distribution based on the type of cases, site of diseases, and service facility through a simple random sampling method. …”
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Artificial intelligence conversational agents in mental health: Patients see potential, but prefer humans in the loop by Hyein S. Lee, Hyein S. Lee, Colton Wright, Julia Ferranto, Jessica Buttimer, Clare E. Palmer, Andrew Welchman, Kathleen M. Mazor, Kimberly A. Fisher, David Smelson, Laurel O’Connor, Laurel O’Connor, Nisha Fahey, Nisha Fahey, Apurv Soni, Apurv Soni, Apurv Soni

“…This study aimed to fill the gap by exploring patients’ perceptions and acceptability of AI conversational agents in mental healthcare.MethodsAdults with self-reported mild to moderate anxiety were recruited from the UMass Memorial Health system. Participants engaged in semi-structured interviews to discuss their experiences, perceptions, and acceptability of AI conversational agents in mental healthcare. …”
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Study protocol for the COPE study: COVID-19 in Older PEople: the influence of frailty and multimorbidity on survival. A multicentre, European observational study by Thomas Lee, Sandeep Singh, Phyo Kyaw Myint, Sheila Jones, Ben Carter, Susan Moug, Terry Quinn, Michael Thomas, Emma Bhatti, Angeline Price, Fenella Barlow-Pay, Siobhan Duffy, Lyndsay Pearce, Arturo Vilches-Moraga, Michael Stechman, Philip Braude, Emma Mitchell, Alessia Verduri, Kathryn McCarthy, Jonathan Hewitt, Charlotte Davey, Kiah Lunstone, Alice Cavenagh, Charlotte Silver, Thomas Telford, Rebecca Simmons, Dolcie Paxton, Francis Rickard, Mark Holloway, James Hesford, Tarik Jichi, Norman Galbraith, Jenny Edwards, Carly Bisset, Ross Alexander, Abigail Ingham, Roxanna Short, Aine McGovern, Jemima Collins, Eilidh Bruce, Alice Einarsson, Enrico Clini, Giovanni Guaraldi, Madeline Garcia, Shefali Sangani, Thomas Kneen, George Kyriakopoulos, Denise Tan

“…Introduction This protocol describes an observational study which set out to assess whether frailty and/or multimorbidity correlates with short-term and medium-term outcomes in patients diagnosed with COVID-19 in a European, multicentre setting.Methods and analysis Over a 3-month period we aim to recruit a minimum of 500 patients across 10 hospital sites, collecting baseline data including: patient demographics; presence of comorbidities; relevant blood tests on admission; prescription of ACE inhibitors/angiotensin receptor blockers/non-steroidal anti-inflammatory drugs/immunosuppressants; smoking status; Clinical Frailty Score (CFS); length of hospital stay; mortality and readmission. …”
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Booster Vaccination against Yellow Fever in Gambian children-(BoVY) -a Phase 3 clinical trial to establish safety and immunogenicity of repeated YF vaccination in healthy Gambian c... by David Jeffries, Caitlin Pley, Beate Kampmann, Mam Nabou Leigh, Julia Strandmark, Ed Clarke, Peter Ndow, Ebrima Kanteh, Amadou Faal, Elishia Roberts

“…Methods This open-label, non-randomised clinical vaccine trial (ClinicalTrials.gov, NCT05332197, registered on 31 March 2022, URL: https://clinicaltrials.gov/study/NCT05332197) will assess the safety and immunogenicity of a booster dose of the licensed 17D YF vaccine in Gambian children. The trial will recruit 750 children in three cohorts of different ages (250 each). …”
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Do you think medicines can be prescribed in a more eco-directed, greener way? A qualitative study based on public and prescriber focus groups on the impact of pharmaceuticals in Sc... by Claire Anderson, Lydia Niemi, Naoko Arakawa, Mark Taggart, Stuart Gibb, Sharon Pfleger

“…Purposive and opportunistic sampling approaches were used to recruit participants through social media and other channels (ie, community groups, professional emails, general practitioner and hospital flyers). …”
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Glucagon, rather than Glucagon-Like Peptide 1, Mediates Higher Post-Lunch Glucose Excursions during Breakfast Skipping in Asian Indian Patients with Uncontrolled Type 2 Diabetes Me... by Yash V. Chauhan, Mahesh D. Hakke, Prudwiraj Sanamandra, Jugal V. Gada, Sukirti Misra, Sachin S. Rahate, Namrata Varekar, Anagha V. Palekar, Premlata K. Varthakavi, Nikhil M. Bhagwat

“…Methods: Cross-over, within-group study recruiting 5 habitual breakfast eaters (BE) and 5 habitual breakfast skippers (BS) with uncontrolled T2DM (HbA1c 7-9%). …”
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Risk Factors for Acute Febrile Reaction after Zoledronic Acid Treatment for Primary Osteoporosis by WU Hongliang, ZHENG Sihang, ZHANG Enchong, HOSSAIN Mohammad Showkat, GONG Helong, XING Ruida, JING Shengjie, LI Yan

“…ObjectiveTo investigate the characteristics and risk factors of acute febrile reaction after zoledronic acid treatment for primary osteoporosis.MethodsA total of 517 patients diagnosed with primary osteoporosis and treated with zoledronic acid from January 2012 to December 2020 were recruited, including 40 males and 477 females, among whom 262 were with type Ⅰ osteoporosis and 255 were with type Ⅱ osteoposis, 245 patients with mild-to-moderate osteoporosis, 272 patients with severe osteoporosis, 230 patients with fresh fracture, and 209 patients with operation. …”
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Principles of effective out-patient diagnostics of diffuse liver diseases by Komova A. G., M. V. Mayevskaya, V. T. Ivashkin

“…In the case of abnormal liver tests preliminary diagnosis was determined according to certain algorithm and these patients were recruited for further investigation and specifications of diagnosis in department of hepatology, University clinical hospital N 2, State educational government-financed institution of higher professional education «Sechenov First Moscow state medical university». …”
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Piloting of a Screen-Triage-Treat Surgical Approach Model for Management of Anal Cancer in Liberia by Christopher W. Reynolds, Whitney Lieb, Andrea Schecter, Michael M Gaisa, Stephen K. McGill, Evans L. Adofo, Ann Marie Beddoe

“…MSM and transgender participants were recruited through convenience sampling with SAIL peer-educators. …”
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Anxiety and depression in primary knee osteoarthritis patients: are they related to clinical features and radiographic changes? by Yasmin A. Abd Elhamid, Ghada S. Elazkalany, Marwa H. Niazy, Angie Y. Afifi

“…Material and methods Fifty patients fulfilling primary knee OA classification criteria were recruited for the study, and 50 age- and sex-matched healthy individuals served as a control group. …”
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Factors Associated with Maternal Near Miss among Women Admitted in West Arsi Zone Public Hospitals, Ethiopia: Unmatched Case-Control Study by Fikadu Nugusu Dessalegn, Feleke Hailemichael Astawesegn, Nana Chea Hankalo

“…Three hundred twenty-one (80 cases and 241 controls) study participants were involved in the study. Cases were recruited consecutively as they present, whereas controls were selected by systematic sampling method. …”
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Development and validation of a prediction model for acute kidney injury following cardiac valve surgery by Xiaotong Jia, Jun Ma, Zeyou Qi, Dongni Zhang, Junwei Gao

“…Using these factors, we developed a risk prediction model for AKI after cardiac valve surgery and conducted external validation.MethodsOur retrospective study recruited 497 adult patients undergoing cardiac valve surgery as a derivation cohort between February and August 2023. …”
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Patterns of pharmacological treatment in patients with atrial fibrillation: an analysis from the prospective GLORIA-AF Registry Phase III by Bernadette Corica, Giulio Francesco Romiti, Giuseppe Boriani, Brian Olshansky, Tze-Fan Chao, Menno V. Huisman, Marco Proietti, Gregory Y. H. Lip, on behalf of the GLORIA-AF Investigators

“…Methods Based on data from the prospective global GLORIA-AF Registry Phase III (recruiting patients with AF and CHA2DS2-VASc score ≥ 1), we performed a latent class analysis to identify treatment patterns based on 14 drug classes including cardiovascular (CV) and non-CV drugs. …”
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Investigation on extended care needs of patients with hypertensive intracerebral hemorrhage (高血压性脑出血患者延续性护理服务需求调查) by QIU Yajiao (邱亚娇), LIANG Hui (梁慧), WANG Fang (王芳)

“…Methods Totally 150 patients with hypertensive intracerebral hemorrhage were recruited in the study, and their extended care needs were investigated by using self-made questionnaire. …”
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Incidence of alexithymia in worsening symptoms and quality of life of Systemic Lupus Erythematosus patients (SLE) by Fabio Rapisarda, Concetta Mezzatesta, Antonina Butticè, Alessandro Raffa, Stefano Boca

“…The group of patients was recruited within the Connetiviti outpatients’ clinic of the UOC (Complex Oparational Unit) of Rheumatology of the Paolo Giaccone University Polyclinic in Palermo, consisting of healthy subjects and/or with known diagnoses identified within non-clinical contexts, chosen randomly (statistical sense) in order to better represent the general population of the territorial context.Specific psycho-diagnostic measures were administered: Toronto Alexithymia Scale (TAS-20), Response Evaluation Measure (REM-71),Attachment Style Questionnaire (ASQ), Eysenck Personality Inventory (EPI),Symptom Check list (SCL-90), Short Form (SF-36). …”
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Mental health in the UK during the COVID-19 pandemic: cross-sectional analyses from a community cohort study by Elizabeth Broadbent, Carol Coupland, Trudie Chalder, Kavita Vedhara, Ru Jia, Kieran Ayling, Adam Massey

“…We focus on the first wave of data collection, which examined short-term consequences for mental health, as reported during the first 4–6 weeks of social distancing measures being introduced.Design Cross-sectional online survey.Setting Community cohort study.Participants N=3097 adults aged ≥18 years were recruited through a mainstream and social media campaign between 3 April 2020 and 30 April 2020. …”
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Exploring Motor Recovery Differences in Paretic Upper and Lower Extremity after Stroke: A Cross-sectional Analytical Study by Rathinasabapathy Sampath Pulimoot, CKV Bhuvaneswari, Annadurai Kabilan

“…A total of 41 stroke participants were recruited through purposive sampling. The Fugl-Meyer Assessment (FMA) scale was used to evaluate both Upper Limb (FMA-UL) and Lower Limb (FMA-LL) motor recovery. …”
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Classification and Statistical Trend Analysis in Detecting Glaucomatous Visual Field Progression by Cristiana Valente, Elisa D’Alessandro, Michele Iester

“…Twenty Caucasian patients (mean age 73.8 ± 13.43 years) with open-angle glaucoma were recruited in the study. Each visual field was assessed by Humphrey Field Analyzer, program SITA standard 30-2 or 24-2 (Carl Zeiss Meditec, Inc., Dublin, CA). …”
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