Combination of Composite Autonomic Symptom Score 31 and Heart Rate Variability for Diagnosis of Cardiovascular Autonomic Neuropathy in People with Type 2 Diabetes by Zhiyin Zhang, Yujin Ma, Liujun Fu, Liping Li, Jie Liu, Huifang Peng, Hongwei Jiang

“…A total of 103 hospitalized subjects with type 2 diabetes were recruited in the study. All cases received clinical data collection, laboratory examination, and related complication examinations. …”
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What all physicians should know about women’s health: a Delphi study by Susanna Price, Eva Gerdts, Julien Mazières, Alexandra Kautzky-Willer, Fedde Scheele, Chiara Benedetto, Kerry Wilbur, Gertraud Stadler, Marieke Wermer, Jeanine Roeters van Lennep, Merel H de Heer-Koster, Vesna Bjegović-Mikanović, Indre Banaitytė-Baleišienė, Mary Perdiou, Alyson McGregor, Connie Newman, Simona Stankevičiūtė, Iris E Sommer, Florence Thibaut, Karine van 't Land

“…This study aimed to reach consensus on what all physicians taking care of women should know about women’s health.Methods A Delphi study was executed involving statements prepared by experts in women’s health across 10 medical specialties and a patient advisory board. Participants were recruited from Europe and Northern America through the experts’ networks and snowball sampling. …”
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CK19 protein expression: the best cutoff value on the prognosis and the prognosis model of hepatocellular carcinoma by Chenglei Yang, Wanyan Xiang, Zongze Wu, Nannan Li, Guoliang Xie, Juntao Huang, Lixia Zeng, Hongping Yu, Bangde Xiang

“…Methods A total of 1,168 HCC patients, who underwent radical surgery at the Guangxi Medical University Cancer Hospital, between January 2014 and July 2019, were recruited, and their clinicopathological data were collected. …”
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A Significant Association of Upper Limb Muscle Strength with Thyroid Function in Overweight and Obese Population: A Study of the Sixth Korea National Health and Nutrition Examinati... by Jeongmin Lee, Kwanhoon Jo, Jeonghoon Ha, Dong-Jun Lim, Jung Min Lee, Sang-Ah Chang, Moo Il Kang, Min-Hee Kim

“…After exclusion of subjects with FT4 level out of normal range, a history of thyroid disease or cerebral disease, restricted activity, and incomplete data, a total of 3503 were recruited (age range 19–80 years, 51% male). FT4 positively correlated with upper limb muscle strength (β coefficient = −12.84, p<0.001), while TSH did negatively (β coefficient = −0.37, p=0.002). …”
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Safety and Efficacy of a 6‐Month Placement of a Fully Covered Self‐Expanding Metallic Stent for Refractory Benign Biliary Stricture: A Multicenter Prospective Study by Tomohisa Iwai, Mitsuhiro Kida, Kazuya Sugimori, Hiroaki Shigoka, Takaaki Matsumoto, Masashi Ijima, Haruo Miwa, Kosuke Okuwaki, Masafumi Watanabe, Kai Adachi, Akihiro Tamaki, Taro Hanaoka, Junro Ishizaki, Chika Kusano

“…Methods Twenty‐two patients with refractory benign biliary stricture (13 with chronic pancreatitis and 9 without) were recruited from five higher tertiary care centers. All patients received a planned 6‐month fully covered self‐expanding metallic stent placement. …”
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‘If one doesn't happen, the other will’: forensic mental health service patients’ experiences of co-occurring self-harm and aggression by Matina Shafti, Peter Taylor, Andrew Forrester, Louise Robinson, Sandeep Mathews, Daniel Pratt

“…Sixteen FMHS patients with a lifetime history of dual harm were recruited from two hospitals. Individuals participated in one-to-one, semi-structured interviews where they reflected on past and/or current self-harm and aggression. …”
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Trial protocol of an open-label pilot study of oral naltrexone–bupropion combination pharmacotherapy for the treatment of methamphetamine use disorder (the NABU trial) by Jonathan Brett, Paul S Haber, Nicholas Lintzeris, Didier Jutras-Aswad, Nadine Ezard, Brendan Clifford, Krista J Siefried, Adrian John Dunlop, Liam Acheson, Carl Moller, Michael Christmass, Kirsten Morley, Steven Shoptaw, Madhukar H Trivedi

“…Primary outcomes are safety (measured by treatment-emergent adverse events (AEs)/adverse reactions) and feasibility (measured by the time taken to recruit, the proportion of ineligible participants, retention in the study and study medication adherence). …”
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Croatian National Data and Comparison with European Practice: Data from the Cardiac Resynchronization Therapy Survey II Multicenter Registry by Sandro Brusich, Ivan Zeljković, Nikola Pavlovic, Ante Anić, Zrinka Jurišić, David Židan, Marina Klasan, Zlatko Čubranić, Kenneth Dickstein, Cecilia Linde, Camilla Normand, Sime Manola

“…Five centres from Croatia recruited consecutive patients, in a 15-month period, who underwent CRT implantation, primary or an upgrade. …”
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Relationship between Urinary Alzheimer-Associated Neuronal Thread Protein and Apolipoprotein Epsilon 4 Allele in the Cognitively Normal Population by Yuxia Li, Meimei Kang, Can Sheng, Guanqun Chen, Taoran Li, Jun Wang, Yanning Cai, Rong Wang, Ying Han

“…We investigated the relationship between urinary Alzheimer-associated neuronal thread protein (AD7c-NTP) levels and apolipoprotein epsilon 4 (ApoE ɛ4) alleles, as well as other factors that cause cognitive decline, in the cognitively normal population. We recruited 329 cognitively normal right-handed Han Chinese subjects who completed ApoE gene testing and urinary AD7c-NTP testing. …”
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Tumor characteristics and survival rate of axillary metastatic breast cancer patients: a three decades retrospective cohort study by Seyed Mohamad Sadegh Mousavi-kiasary, Mahdis Bayat, Fereshteh Abbasvandi, Batoul Khoundabi, Fatemeh Mousavi, Atieh Akbari, Maryam Bagherian, Afsoon Zandi, Behnam Honarvar, Mohammad Esmaeil Akbari

“…Result: Among the total 3399 recruited patients, 49.1%, 26.3%,13.1%, and 6.4% were pN0, pN1, pN2 and pN3, respectively. …”
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Cerebrospinal fluid‐specific oligoclonal bands in dogs with idiopathic epilepsy by Junwei Föhr, Julia K. Prümmer, Arianna Maiolini, Eliane Marti, Ilijas Jelcic, Beatriz Vidondo, Mario Ziegler, Andrea Bathen‐Nöthen, Andrea Tipold, Holger A. Volk, Veronika M. Stein

“…Animals Eighty‐four dogs with IE were recruited from 3 referral centers and classified based on their response to ASM treatment (responsive, n = 56; resistant, n = 28). …”
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Diagnostic accuracy of human papillomavirus testing on self-collected samples among women referred for colposcopy by ChunX Yan, Jiong Ma, Xia Zheng, Jing Shu, XiaoJ Wang, XiaoY Chen, Feng Gao, XiaoQ Li, ShanQ M, LongM Huang, XiaoT Yu, XueJ Chen

“…A total of 1,701 women were recruited with 113 women excluded. Among 1,588 qualified participants, a total of 203 cases of the CIN2 + group were enrolled in the two centers. …”
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Default mode network-basal ganglia network connectivity predicts the transition to postherpetic neuralgia by Ying Wu, Chao Wang, Wei Qian, Lieju Wang, Lina Yu, Minming Zhang, Min Yan

“…Methods: In this cross-sectional study, 31 patients with PHN, 33 with recuperation from herpes zoster (RHZ), and 28 with acute herpes zoster (AHZ) were recruited and underwent resting-state functional magnetic resonance imaging (fMRI). …”
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Clinical efficacy of a virtual reality tool for the treatment of obesity: study protocol of a randomised controlled trial by Dimitra Anastasiadou, Jose Antonio Ramos-Quiroga, Mel Slater, Bernhard Spanlang, Desiderio Cano Porras, Marta Comas, Andreea Ciudin, Gemma Parramon Puig, Julia Vázquez-De Sebastián, Pilar Lusilla-Palacios

“…Participants will be recruited from the external consultations of the Vall d'Hebron University Hospital and be randomly assigned to three groups. …”
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Involvement of the Dectin-1 Receptor upon the Effector Mechanisms of Human Phagocytic Cells against Paracoccidioides brasiliensis by Juliana Carvalho de Quaglia e Silva, Amanda Manoel Della Coletta, Taiane Priscila Gardizani, Graziela Gorete Romagnoli, Ramon Kaneno, Luciane Alarcão Dias-Melicio

“…When the fungus reaches the lungs and interacts with the alveolar macrophages and other cells, phagocytic cells such as neutrophils and monocytes are immediately recruited to the injured site. The interaction between surface molecules of pathogens and homologous receptors, present on the surface membrane of phagocytes, modulates the innate immune cell activation. …”
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Transcriptional analysis of murine biliary atresia identifies macrophage heterogeneity and subset-specific macrophage functions by Kyle D. Gromer, Shang-Yang Chen, Gaurav Gadhvi, Liang Feng, Colin Shearn, Swati Antala, Swati Antala, Joshua B. Wechsler, Carla M. Cuda, Cara L. Mack, Ronald J. Sokol, William J. Janssen, Richard M. Green, Harris Perlman, Deborah R. Winter, Sarah A. Taylor, Sarah A. Taylor

“…We aimed to distinguish the transcriptional profiles and roles of defined macrophage subset(s) in murine BA.MethodsWe used multiparameter flow cytometry and RNA-sequencing analysis to profile recruited CD11bhiCD64+ hepatic macrophages by cell surface expression of MHCII and Ly6c in the Rhesus rotavirus (RRV)-induced murine model of BA versus saline controls. …”
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Protocol for a mixed-methods randomised controlled trial evaluating the psychosocial effects of an expressive arts-based intervention on adults with age-related macular degeneratio... by Qing Li, Temmy Lee Ting Lo, Rainbow Tin Hung Ho, Adrian Ho Yin Wan, Ted Chun Tat Fong, Caitlin Kar Pui Chan, Allen Ming Yan Cheong, Wai Chi Chan

“…One hundred fifty-four participants with AMD will be recruited and randomised into either the EXABI or treatment-as-usual waitlist control group. …”
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Validation of deep-learning accelerated quantitative susceptibility mapping for deep brain nuclei by Ying Zhou, Ying Zhou, Lingyun Liu, Shan Xu, Yongquan Ye, Ruiting Zhang, Minming Zhang, Jianzhong Sun, Peiyu Huang

“…Finally, the correlations between age and QSM values in the selected deep brain nuclei were evaluated.Results59 participants were recruited. Compared to PI-QSM images, the mean SSIM of DL images were 0.87, 0.86, and 0.85 for AF of 3, 4, and 5. …”
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Nourishing change in Houston, Texas: exploring grocery shopping behaviours and fruit and vegetable consumption among low-income families in the Brighter Bites program by Victoria Kwentua, Allison Marshall, Ru-Jye Chuang, Jessica Chen, Christine Markham, Mallika Mathur, Mike Pomeroy, Megan Hall, Shreela Sharma

“…We used (1) purposive sampling of schools and (2) convenience sampling of parents/caregivers to recruit participants. Research staff conducted three face-to-face qualitative focus groups in Spanish and English. …”
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Protocol for a prospective observational cohort study of cutaneous leishmaniasis in Ethiopia [version 2; peer review: 2 approved, 1 approved with reservations] by Fewzia Shikur Mohammed, Amel Beshir Mohammed, Shimelis Doni Nigusse, Feleke Tilahun Zewdu, Abebaw Yeshambel Alemu, Teklu Cherkose, Kidist Bobosha, Eshetu Molla, Iris Mosweu, Vanessa Yardley, Saba Maria Lambert, Mirgissa Kaba, Endalamaw Gadisa, Yohannes Hailemichael, Catherine Pitt, Elizabeth Allen, Stephen L. Walker, Michael Marks

“…Methods We have designed an observational, multi-centre cohort study to examine treatment outcomes for CL in Ethiopia which includes clinical outcomes, laboratory outcomes, patient reported outcome measures, scar assessments and cost effectiveness. We aim to recruit up to 750 participants across two hospital sites. …”
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