Vitamin D associates with improved quality of life in participants with irritable bowel syndrome: outcomes from a pilot trial by Sue F Plummer, Iveta Garaiova, Elizabeth A Williams, Bernard M Corfe, Simon Tazzyman, Nicholas Richards, Andrew R Trueman, Amy L Evans, Vicky A Grant

“…Vitamin D status was determined by blood test at baseline and exit; IBS symptoms were assessed by validated questionnaire; dietary intakes were assessed by food frequency questionnaire.Results A significant proportion of the IBS population were vitamin D deficient, such that the replete stratum could not be adequately recruited. There was a significant association in the baseline data between circulating vitamin D level and quality of life (“How much has IBS affected your life?”). …”
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Patient experience with eosinophilic esophagitis symptoms and impacts on daily life based on in-trial qualitative interviews by Calvin N. Ho, Harald Fjällbrant, Evan S. Dellon, Cecilio Santander, Marc E. Rothenberg, Julie Bailey, Shehan McFadden, Jason Ritchie

“…Results The MESSINA trial was terminated prematurely. Of the 34 patients recruited for the first interview, 15 (44%) completed the second interview and 11 patient profiles were developed. …”
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Subgroups of cognitive impairments in schizophrenia characterized by executive function and their morphological features: a latent profile analysis study by Yuyan Huang, Weiyan Wang, Gangrui Hei, Tiannan Shao, Li Li, Ye Yang, Xiaoyi Wang, Yujun Long, Jingmei Xiao, Xingjie Peng, Chuhan Song, Jingda Cai, Xueqin Song, Xijia Xu, Shuzhan Gao, Jing Huang, Dongyu Kang, Ying Wang, Jingping Zhao, Yunzhi Pan, Renrong Wu

“…Methods A total of 920 schizophrenia patients and 169 healthy controls were recruited. MATRICS Consensus Cognitive Battery was applied to assess cognitive performance and recognize cognitive subgroups through latent profile and latent transition analysis. …”
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Identification of serum tRNA-derived small RNAs biosignature for diagnosis of tuberculosis by Zikun Huang, Qing Luo, Cuifen Xiong, Haiyan Zhu, Chao Yu, Jianqing Xu, Yiping Peng, Junming Li, Aiping Le

“…A total of 905 subjects were prospectively recruited for our study from three different cohorts. …”
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Relationship between psychological empowerment, physical activity enjoyment, and response to a HIIT Program in physically inactive young women: a prospective multicentre study by Irene Ferrando-Terradez, Rodrigo Núñez-Cortés, Laura López-Bueno, Enrique Alcántara, Joaquín Calatayud, José Casaña, Ivana Parčina, Lirios Dueñas

“…Methods A total of 61 physically inactive young women (age: 20.1 ± 2.7 y) were recruited to participate in a six-month HIIT intervention delivered via a smartphone app. …”
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Immediate effect of electrical vestibular stimulation on autonomic and respiratory parameters and reaction time in patients with Parkinson’s disease by Asha G, Varun Manjunath, Karthik N, Yashica Gowda R, Sai Sailesh Kumar Goothy, Rohit Singh Chouhan, Anitha Lakshmi

“…Materials and Methods: The present study recruited 30 patients with PD after obtaining written informed consent. …”
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Congenital muscular dystrophies and myopathies: the leading cause of genetic muscular disorders in eleven Chinese families by Bin Mao, Xiaoling Cai, Na Lin, Yulin Jiang, Na Hao, Yifang Dai, Danhua Guo, Deqin He, Huili Xue, Lingji Chen, Qianqian He, Min Zhang, Meihuan Chen, Hailong Huang, Liangpu Xu

“…Abstract Background Congenital muscular dystrophies (CMDs) and myopathies (CMYOs) are a clinically and genetically heterogeneous group of neuromuscular disorders that share common features, such as muscle weakness, hypotonia, characteristic changes on muscle biopsy and motor retardation. In this study, we recruited eleven families with early-onset neuromuscular disorders in China, aimed to clarify the underlying genetic etiology. …”
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Muscular Performance and Blood Pressure After Different Pre-Strength Training Strategies in Recreationally Strength-Trained Women: Cross-Over Trial by Estêvão Rios Monteiro, Linda S. Pescatello, Luis Leitão, Marcelo José Colonna de Miranda, Paulo H. Marchetti, Michelle Ribeiro Novaes, Gleisson da Silva Araújo, Victor Gonçalves Corrêa Neto, Jefferson da Silva Novaes

“…Methods: Twelve overweight women with normal BP were recruited and performed six experimental protocols in a randomized order: (1) control protocol (CC), where BP was assessed without exercises performed; (2) ST; (3) foam rolling warm-up followed by ST (FR + ST); (4) specific warm-up followed by ST (SW + ST); (5) aerobic exercise followed by ST (AE + ST); and (6) stretching exercises followed by ST (SE + ST). …”
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Evaluating novel approaches for estimating awake and sleep blood pressure: design of the Better BP Study – a randomised, crossover trial by Paul Muntner, Ligong Chen, Daichi Shimbo, Joseph E Schwartz, Maria Cepeda, Demetria Hubbard, Suzanne Oparil, Byron C Jaeger, Shakia T Hardy, Julia Medina

“…The aims of the Better BP Study are to (1) test if unattended office BP is closer to awake BP on ABPM compared with attended office BP, (2) assess if sleep BP assessed by home BP monitoring (HBPM) agrees with sleep BP from a full night of ABPM and (3) compare the strengths of associations of unattended versus attended office BP, unattended office BP versus awake BP on ABPM and sleep BP on HBPM versus ABPM with markers of end-organ damage.Methods and analysis We are recruiting 630 adults not taking antihypertensive medication in Birmingham, Alabama, and New York, New York. …”
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Usefulness of the Hybrid RFR-FFR Approach: Results of a Prospective and Multicenter Analysis of Diagnostic Agreement between RFR and FFR—The RECOPA (REsting Full-Cycle Ratio Compar... by Juan Casanova-Sandoval, Diego Fernández-Rodríguez, Imanol Otaegui, Teresa Gil Jiménez, Marcos Rodríguez-Esteban, Kristian Rivera, Francisco Torres-Saura, Víctor Jiménez Díaz, Raymundo Ocaranza-Sánchez, Vicente Peral Disdier, Guillermo Sánchez-Elvira, Fernando Worner

“…Patients subjected to invasive physiological study in 9 Spanish centers were prospectively recruited between April 2019 and March 2020. Sensitivity and specificity studies were made to assess diagnostic accuracy between the recommended levels of RFR ≤0.89 and FFR ≤0.80 (primary objective) and to determine the RFR “grey zone” in order to define a hybrid strategy with FFR affording 95% global agreement compared with FFR alone (secondary objective). …”
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Assessment of patient preferences for assisted reproductive technology in China: a discrete choice experiment by Lingli Zhang, Xin Li, Jiali Chen, Yanyan Liu, Yanjun Sun, Yuwen Bao, Xiaodan Qian, Kexing Fang, Bin Wan, Haixia Ding

“…The anonymous survey was carried out between December 2022 and February 2023.Participants Female patients aged 20–45 years, with low fertility or experience of ART treatment. We recruited 465 participants.Outcomes measures Patient-reported preferences for each attribute were estimated using a mixed logit model. …”
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Association of dust exposure with anxiety and depression in the occupational population: The important role of sleep duration by Zhuoheng Shen, Yue Sun, Yang Li, Qi Zhang, Yifei Liu, Jiyan Han, Jiafei Yang, Jiangping Li, Zhiyun Ha, Yaowen Yang, Zhihong Liu, Suzhen Guan, Jian Sun

“…Methods This study was conducted from July to October 2023 at The Fifth People's Hospital of Ningxia and recruited dust-expose d occupational workers from different coal enterprises. …”
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Smartphone video games for cognitive functions and negative symptoms in male with chronic schizophrenia: A randomized controlled trial by Wenhui Wang, Mengting Ye, Yongjie Zhong, Miaomiao Zhang, Yue Wang, Chuanchuan Chen, Yitan Yao, Ziqiao Feng, Xiaoping Yuan, Shenya Shi, Xiaoqin Zhou, Kai Zhang

“…Methods: We conducted a 6-week randomized controlled trial to compare the cognitive function, psychotic symptoms, overall functioning, and other outcomes of schizophrenic patients who engaged in smartphone video games (game group) with those who watched television programs (control group). We recruited schizophrenic patients who met the eligibility criteria from July 2021 to February 2022. …”
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Determinants of Work-Related Risks among Veterinary Clinical Students in South West Nigeria by Oluwawemimo O. Adebowale, Monsurat O. Afolabi, Hezekiah K. Adesokan, Olubunmi G. Fasanmi, Olanike K. Adeyemo, Olajoju J. Awoyomi, Folorunso O. Fasina

“…Data on demographics, health and safety (HS) status, work-related hazards, healthcare facilities, and immunisation history were obtained. Of 167 students recruited, 100 (60.2%) were males, and >77.1% fell within the age group of 21–25 years. …”
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Signatures of lower respiratory tract microbiome in children with severe community-acquired pneumonia using shotgun metagenomic sequencing by Ting-Yu Yen, Ching Hsu, Ni-Chung Lee, Chao-Szu Wu, Hsin Wang, Kuan-Yi Lee, Chia-Ray Lin, Chun-Yi Lu, Mo-Li Tsai, Tzu-Yu Liu, Che Lin, Chien-Yu Chen, Luan-Yin Chang, Feipei Lai, Li-Min Huang

“…Methods: We conducted a prospective cohort study to recruit children under 18 who required admission to an intensive care unit for community-acquired pneumonia between December 2019 and February 2022. …”
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A Conversational Agent for Empowering People with Parkinson’s Disease in Exercising Through Motivation and Support by Patricia Macedo, Rui Neves Madeira, Pedro Albuquerque Santos, Pedro Mota, Beatriz Alves, Carla Mendes Pereira

“…The User Experience Study involved eight PwPD users recruited from Portuguese healthcare units performing predefined tasks, with user satisfaction scores ranging from 4.2 to 4.9 on a five-point Likert scale. …”
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Gut Microbiota as Mediator and Moderator Between Hepatitis B Virus and Hepatocellular Carcinoma: A Prospective Study by Bingren Hu, Yi Yang, Jiangqiao Yao, Ganglian Lin, Qikuan He, Zhiyuan Bo, Zhewei Zhang, Anlvna Li, Yi Wang, Gang Chen, Yunfeng Shan

“…Materials and Methods A total of 640 patients with chronic liver diseases or HCC were prospectively recruited between 2019 and 2022. Fecal samples were collected and subjected to 16S rRNA gene sequencing. …”
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Comparison of the accuracy of procalcitonin, neutrophil CD64, and C-reactive protein for the diagnosis and prognosis of septic patients after antibiotic therapy by Qingteng Zhu, Hui Wang, Liang Chen, Yang Yu, Miao Chen

“…Methods: This study prospectively recruited consecutive patients without infection and those diagnosed with infection but had received initial antimicrobial therapies. …”
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Effectiveness of 12 weeks of listening to Gayatri Mantra in the management of non-motor symptoms in patients with Parkinson’s disease: A pilot study by Puneeth Nagarajaiah, Naveen Raj GM, Anil Mohan Rao S, Sai Sailesh Kumar Goothy, Mukkadan JK

“…Materials and Methods: The present pilot study recruited 20 patients with Parkinson’s disease. The patients acted as self-controls. …”
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Protocol for process evaluation of SMART Mental Health cluster randomised control trial: an intervention for management of common mental disorders in India by Anushka Patel, David Peiris, Pallab K Maulik, Graham Thornicroft, Shekhar Saxena, Sudha Kallakuri, Amanpreet Kaur, Siddhardha Devarapalli, Mercian Daniel, Beverley M Essue, Shashi Kant, D Praveen, Usha Raman, Rajesh Sagar, Ankita Mukherjee

“…Qualitative data sources will include focus group discussions and interviews with recruited participants, primary health centre doctors, community health workers (Accredited Social Health Activits) who participated in the project and local community leaders. …”
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