Usefulness of perampanel as initial monotherapy in children with non-lesional focal epilepsy by Hideaki Kanemura, Yoshihiro Miyasato, Yutaro Tomi, Fumikazu Sano

“…This retrospective review included participants recruited from among epilepsy outpatients treated at the authors’ hospital between January 01, 2000, and December 31, 2019 in the CBZ group and between January 01, 2020, and December 31, 2022 in the PER group. …”
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Factors affecting knowledge and attitude of healthcare workers towards basic life support in Khyber Teaching Hospital, Peshawar, Pakistan: a cross-sectional analysis by Umair Hayat, Ali Ahmad, Samar Hasnain, Jehan Hussan, Laiba Khan, Shabir Muhammad, Khkula Kamal, Sawaira, Areej Abbasi, Muhammad Akhlaq, Khizar Ahmad

“…Objective This study was conducted to assess the knowledge and attitude of healthcare workers towards basic life support (BLS) in Khyber Teaching Hospital, Peshawar, and to investigate the factors affecting them.Design Cross-sectional study.Setting This study was carried out in a tertiary care hospital in Peshawar, Pakistan.Participants 201 healthcare professionals were recruited for this study through simple convenience sampling which included house officers (HOs), trained medical officers, postgraduate residents, professors, specialty registrars and nurses. …”
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Single-cell transcriptomics reveals novel chondrocyte and osteoblast subtypes and their role in knee osteoarthritis pathogenesis by Yuan Liu, Wacili Da, Ming-Jie Xu, Chao-Xin Xiao, Tao Deng, Sheng-Liang Zhou, Xiao-Ting Chen, Yao-Jia Zhou, Li Tang, Yong Nie, Yi Zeng, Hui-Qi Xie, Bin Shen

“…The number of H-type vessels was increased in the subchondral bone, recruiting osteoprogenitor cells and facilitating osteogenesis in KOA mice. …”
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Biting force and tongue muscle strength as useful indicators for eating and swallowing capability assessment among elderly patients by Xinmiao Wang, Gangying Zheng, Mingsong Su, Yanqiu Chen, Hua Xie, Weijia Han, Qing Yang, Jianqin Sun, Jianshe Chen

“…A total of 26 elderly patients with potential swallow disorder were recruited in this work. Participants’ denture status and daily diet texture were determined by a pre-questionnaire analysis. …”
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Mitigating climate change with financial investments: exploring sustainable investment strategies in a novel experimental investment paradigm by Hulda Karlsson-Larsson, Arvid Erlandsson, Joakim Sandberg, Daniel Västfjäll

“…The relative use of these strategies was tested within a novel investment paradigm, aiming to artificially create a trade-off between financial payoffs (money maximization), environmental purity (exclusion), and environmental impact (inclusion). We recruited 1422 participants online and let them make ten consecutive investment choices, with incentivized outcomes, both monetary (i.e., potential bonus payment) and environmental (i.e., number of trees planted). …”
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Systemic Chemotherapy prior to Cytoreductive Surgery and HIPEC for Carcinomatosis from Appendix Cancer: Impact on Perioperative Outcomes and Short-Term Survival by Lana Bijelic, Anjali S. Kumar, O. Anthony Stuart, Paul H. Sugarbaker

“…Thirty-four patients with PMCA were prospectively recruited and treated with PSC. Perioperative variables and survival in this group of patients were compared against 24 patients with PMCA who did not receive PSC. …”
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Prevalence of Intestinal Protozoa among Saudi Patients with Chronic Renal Failure: A Case-Control Study by Yousry A. Hawash, Laila Sh. Dorgham, El-Amir M. Amir, Osama F. Sharaf

“…Fifty diarrheal patients without CRF were recruited in the study as controls. Participants were interviewed by a structured questionnaire and stool samples were collected. …”
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Stakeholders’ Perspectives on Child Healthcare Services under Rural Health Reform in Thailand: A Qualitative Study by Katemanee Moonpanane, Salisa Kodyee, Pimkanabhon Trakooltorwong, Kunnara Maneekunwong, Chompunut Sopajaree

“…Participants (N=45) including twenty parents, ten healthcare providers, five village health volunteers, five teachers, and five community leaders were recruited using purposive sampling. In-depth interviews and focus group discussions, lasting between 40 and 70 minutes, were performed to explore the participants’ perspectives. …”
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Analysis of the Serum Bile Acid Composition for Differential Diagnosis in Patients with Liver Disease by Tomonori Sugita, Katsushi Amano, Masanori Nakano, Noriko Masubuchi, Masahiro Sugihara, Tomokazu Matsuura

“…A total of 150 subjects, including patients with hepatitis C virus (HCV) (n=44), hepatitis B virus (HBV) (n=23), alcoholic liver disease (ALD) (n=21), biliary tract disease (n=20), nonalcoholic fatty liver disease (NAFLD) (n=13), and other liver diseases (n=29), were recruited. The levels of UDCA and GUDCA were significantly higher in the ALD group, and the levels of DCA and UDCA were significantly lower in the biliary tract diseases group than in viral hepatitis group. …”
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Adhesive and injectable hydrogel microspheres for NRF2-mediated periodontal bone regeneration by Yu Wang, Shanshan Jin, Yaru Guo, Yilong Lu, Xuliang Deng

“…MMS-CY could adhere to the surface of alveolar bone, then promote the migration capacity of PDLSCs and thus recruit them to inflammatory periodontal tissues. …”
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Risk Factors for Gestational Diabetes Mellitus in a Large Population of Women Living in Spain: Implications for Preventative Strategies by Ana M. Ramos-Leví, Natalia Pérez-Ferre, M. Dolores Fernández, Laura del Valle, Elena Bordiu, Ana Rosa Bedia, Miguel A. Herraiz, M. José Torrejón, Alfonso L. Calle-Pascual

“…The aim of this study is to establish a risk appraisal model for GDM by identifying modifiable factors that can help predict the risk of GDM in a large population of 2194 women living in Spain. They were recruited between 2009-2010 when screening for GDM was performed. …”
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Reducing Colorectal Cancer Incidence and Disparities: Performance and Outcomes of a Screening Colonoscopy Program in South Carolina by Sudha Xirasagar, Yi-Jhen Li, James B. Burch, Virginie G. Daguisé, Thomas G. Hurley, James R. Hébert

“…Data on procedures and patient demographics were analyzed. Of 782 individuals recruited (71.2% AA), 85% (665) completed the procedure (71.1% AA). …”
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A Network Investigation on Idiopathic Hypogonadotropic Hypogonadism in China by Weiwei Zhao, Hongying Ye, Xiaolong Zhao, Zhaoyun Zhang, Shouyue Sun, Yiran Jiang, Min He, Cheng Xu, Renming Hu, Yiming Li

“…A total of 74 male IHH patients were recruited from the Chinese largest IHH network social group. …”
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Engaging older adults in diagnostic safety: implementing a diagnostic communication note sheet in a primary care setting by Alberta Tran, Leah Blackall, Mary A. Hill, Mary A. Hill, William Gallagher

“…Diagnostic communication interventions, such as the Agency for Healthcare Research and Quality's “Be the Expert on You” note sheet, may require adaptations to address older adults' unique needs.MethodsWe recruited and partnered with older adult patients (n = 6) in focus group sessions to understand their perspectives on diagnostic communication and the existing AHRQ note sheet. …”
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Hippocampal Atrophy in Systemic Lupus Erythematosus Patients without Major Neuropsychiatric Manifestations by Shuang Liu, Yuqi Cheng, Yueyin Zhao, Aiyun Lai, Zhaoping Lv, Zhongqi Xie, Bibhuti Upreti, Xiangyu Wang, Xiufeng Xu, Chunrong Luo, Hongjun Yu, Baoci Shan, Lin Xu, Jian Xu

“…Eighty-five non-NPSLE patients with normal conventional magnetic resonance imaging (MRI) and seventy-seven matched healthy control (HC) subjects were recruited. All participants underwent the standard high-resolution volumetric MRI. …”
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Diagnostic Value of the 13C Methacetin Breath Test in Various Stages of Chronic Liver Disease by Hamizah Razlan, Nurhayaty Muhamad Marzuki, Mei-Ling Sharon Tai, Azhar-Shah Shamsul, Tze-Zen Ong, Sanjiv Mahadeva

“…Seventy-seven patients (47 men/30 women, mean age 50±16 years) were recruited. Forty-seven patients had liver cirrhosis (Child Pugh A = 11, Child Pugh B = 15, and Child Pugh C = 21), 21 had fibrosis, and 9 had chronic inflammation. …”
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Healthcare access, attitudes and behaviours among Navajo adults during the COVID-19 pandemic: a cross-sectional study by Robin B Harris, Carmenlita Chief, Heidi E Brown, Rachelle L Begay, Priscilla R Sanderson, Breanna Lameman

“…Objective To assess factors associated with positive COVID-19 tests, perspectives on health-related care delivery during pandemic and factors supporting resilience among members of the Navajo Nation.Methods and analysis From May through October 2021, a multi-institutional team recruited participants (n=154) to complete a 49-item questionnaire or participate in a focus group (n=14) about their experience with COVID-19 and the effects on their use and access to allopathic and traditional healthcare. …”
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Polymorphism rs3828903 within MICB Is Associated with Susceptibility to Systemic Lupus Erythematosus in a Northern Han Chinese Population by Yue-miao Zhang, Xu-jie Zhou, Fa-juan Cheng, Yuan-yuan Qi, Ping Hou, Ming-hui Zhao, Hong Zhang

“…This study aimed to investigate the association in a northern Han Chinese population. Methods. We recruited 1077 SLE patients and 793 controls for analysis. rs3828903 was genotyped by TaqMan allele discrimination assay. …”
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Cardiac cycle: an observational/interventional study protocol to characterise cardiopulmonary function and evaluate a home-based cycling program in children and adolescents born ex... by Jeanie L Y Cheong, Michael M H Cheung, Melanie M Clarke, Jonathan P Mynard, Claire E Willis

“…Fifty-eight children and adolescents aged 10–18 years who were born EP and/or with ELBW will be recruited. Cardiopulmonary function assessed via measures of blood pressure, arterial stiffness, capillary density, peak oxygen consumption, lung clearance indexes and ventricular structure/function, will be compared with 58 age-matched and sex-matched term-born controls at baseline and post intervention. …”
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Topical transdermal administration of lenalidomide nanosuspensions-based hydrogels against melanoma: In vitro and in vivo studies by Mengdi Zhang, Haiying Qiu, Zheyi Han, Yazhong Ma, Jingjing Hou, Jingwei Yuan, Haiyan Jia, Menglu Zhou, Hongjie Lu, Yan Wu

“…Mechanistically, lenalidomide reversed the abnormal activation of the PI3K-AKT signaling pathway and the overexpression of CD93, while also recruiting CD8+ T cells, CD4+ T cells, and dendritic cells to infiltrate the tumor site. …”
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