Polycaprolactone for Hard Tissue Regeneration: Scaffold Design and In Vivo Implications by Fernanda Ramírez-Ruiz, Israel Núñez-Tapia, María Cristina Piña-Barba, Marco Antonio Alvarez-Pérez, Vincenzo Guarino, Janeth Serrano-Bello

“…Bone tissue is characterized by different stiffness, mechanical traction, and compression resistance as a function of the different compartments, which can influence susceptibility to injury or destruction. For this reason, research into repairing bone defects began several years ago to find a scaffold to improve bone regeneration. …”
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Re-defining pT4b buccal mucosa squamous cell carcinoma: Looking beyond palliation in select patients by Prateek V. Jain, Kapila Manikantan, Gary M. Clark, Indranil Mallick, Sanjoy Chatterjee, Indu Arun, Paromita Roy, Lateef Zameer, Pattatheyil Arun

“…Objectives: Reports in the last 2 decades suggest that selected patients with masticator space invasion can be treated surgically with reasonable survival. This study is an attempt to identify prognosticators for disease free (DFS) and overall survival (OS) in surgically treated pT4 buccal mucosa squamous cell carcinoma (BMSCC) patients. …”
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Revealing novel protein interaction partners of glyphosate in Escherichia coli by Alix Sarah Aldehoff, Dominique Türkowsky, Patrick Lohmann, Masun Nabhan Homsi, Ulrike Rolle–Kampczyk, Elke Ueberham, Jörg Lehmann, Martin von Bergen, Nico Jehmlich, Sven–Bastiaan Haange

“…Similar to the competitive binding between PEP and glyphosate at EPSPS, one reason for the interaction of AroH and ProA with the herbicide could be a high structural similarity between their substrates and glyphosate. …”
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Photon sensor-based monitoring of spatial variations in canopy FIPAR for crop growth assessment by Jian Wang, Zhenggui Zhang, Xin Li, Lu Feng, Xiaofei Li, Minghua Xin, Shiwu Xiong, Yingchun Han, Shijie Zhang, Xiaoyu Zhi, Beifang Yang, Guoping Wang, Yaping Lei, Zhanbiao Wang, Yabing Li

“…The technology was developed to provide reasonably accurate crop growth information while balancing cost requirements for applications in both scientific research and agricultural production, offering high potential for guiding smart crop management to enhance agricultural productivity.…”
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Generation of Insulin-Producing Cells from Canine Adipose Tissue-Derived Mesenchymal Stem Cells by Takahiro Teshima, Keiji Okamoto, Kazuho Dairaku, Tomokazu Nagashima, Masaki Michishita, Ryohei Suzuki, Hirotaka Matsumoto, Hidekazu Koyama

“…Several factors, such as the transplanted cell number, the origin of AT-MSCs, and the differentiation protocol, were considered potential reasons for the inability to improve the hyperglycemic state after IPC transplantation. …”
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Promotion mechanism of hydroxyl groups in catalyzing CO2 cycloaddition by Yiming Wang, Wensheng Wei, Yuxin Wang, Guangwen Xu, Jinggang Zhao, Lei Shi

“…The promoting effects of the hydroxyl-group content, position and connection structure in different alcohol additives on the CO2 cycloaddition reaction were further investigated and the results demonstrated that when the additive molecule contains an appropriate number of ortho-hydroxyl groups and these hydroxyl groups are connected to groups with strong electron-withdrawing ability and small steric hindrance, the cycloaddition efficiency between PO and CO₂ can be significantly enhanced. The reason is that these hydroxyl groups not only provide more hydrogen bonds, enhancing the intermolecular interactions, but also help to stabilize the transition state of the reaction. …”
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Enhanced protective effect of selenium-biofortified peptide RYNA(Se)MNDYT compared with its native peptide RYNAMNDYT in lipopolysaccharide-injured murine gut microbiota by Shujian Wu, Zhenjun Zhu, Mengfei Chen, Aohuan Huang, Yizhen Xie, Jiaming Chen, Liang Xue, Moutong Chen, Jumei Zhang, Juan Wang, Qingping Wu, Yu Ding

“…This may be one of the key reasons for Se-P2 to exert bioactivity through the microbiota-metabolite axis. …”
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Changes in payer mix of new and established trauma centers: the new trauma center money grab? by Patrick Kim, Elinore Kaufman, Jeremy W Cannon, Justin Hatchimonji, Patrick M Reilly, Satvika Kumar, Diane N Haddad

“…Hospitals may seek TC accreditation for financial reasons, rather than to address community or geographic need. …”
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Application of artificial intelligence brain structure-based paradigm to predict the slip condition impact on magnetized thermal Casson viscoplastic fluid model under combined temp... by Umar Farooq, Shan Ali Khan, Haihu Liu, Muhammad Imran, Lotfi Ben Said, Aleena Ramzan, Taseer Muhammad

“…One of the main reasons for the popularity of ANNs is their wonderful capability to handle very complex and nonlinear mathematical problems. …”
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A strategy for selective screening of dual-target bioactive compounds against hypertrophic scar through inhibiting angiotensin II type 1 receptor while stimulating type 2 receptor... by Lejing Qu, Meizhi Jiao, Zilong Zhang, Yuanyuan Ou, Xue Zhao, Yajun Zhang, Xinfeng Zhao

“…Conversely, the bindings of the two compounds to AT2R reduced the production of nuclear factor-кB1 (NF-кB1), whereby the generation of interleukin-6 (IL-6) was blocked. Conclusion We reasoned that aloe-emodin and emodin had the potential to become dual-target candidates against hypertrophic scar through the regulation of AT1R and AT2R signaling pathways. …”
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Oligogenic effect is associated with the clinical heterogeneity of autosomal dominant deafness-15 by Jianyan Pan, Hua Teng, Fang Liu, Siyi Chen, Yaning Liu, Yanling Teng, Desheng Liang, Zhuo Li, Lingqian Wu

“…Abstract Autosomal dominant deafness-15 which is caused by mutation in the POU4F3 gene, has been reported with a wide degree of clinical heterogeneity, even between intrafamilial members. However, the reason is still elusive. In this study, A four-generation Chinese family with 11 patients manifesting late-onset progressive non-syndromic hearing loss was recruited. …”
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Evaluation of Wisconsin and CaPTHUS Indices Usefulness for Predicting Monoglandular and Multiglandular Disease in Patients with Primary Hyperparathyroidism through the Analysis of... by Loredana De Pasquale, Eleonora Lori, Antonio Mario Bulfamante, Giovanni Felisati, Luca Castellani, Alberto Maria Saibene

“…The main challenge for treating primary hyperparathyroidism (PHPT) is to understand if it is caused by a single adenoma (80–85% of the cases) or by a multiglandular disease (15–20%), both preoperatively and intraoperatively. For this reason, some preoperative scores were proposed in the literature, to perform focused parathyroidectomy, avoiding intraoperative parathormone assay (ioPTH). …”
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Perioperative SARS-CoV-2 Infection in Patients Undergoing Elective Surgery in Gynecology Clinic: Tertiary Center Experience by Gulnihal Reyhan Toptas, Eylem Unlubilgin, Tugba Kinay, Ali Riza Dogan, Mehmet Akif Akgul, Sitare Aslanova, Emel Ebru Ercan, Vakkas Korkmaz, Sezin Erturk Aksakal, Yaprak Ustun

“…RESULTS: Operations of 133 (33%) of 406 patients were canceled for various reasons. 275 patients were operated on. Preoperatively three patients were diagnosed with COVID-19. …”
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Prevalence of Diabetes and Associated Risk Factors among a Group of Prisoners in the Yaoundé Central Prison by Sylvain Raoul Simeni Njonnou, Jérôme Boombhi, Martine Claude Etoa Etoga, Aimée Tiodoung Timnou, Ahmadou Musa Jingi, Kevin Nkem Efon, Esther Astrid Mbono Samba Eloumba, Marie-Josiane Ntsama Essomba, Odette Kengni Kebiwo, Alice Ninon Tsitsol Meke, Stéphane Talbit Ndjonya, Mesmin Dehayem Yefou, Eugène Sobngwi

“…Analyzed variables included phenotypic characteristics, lifestyle, the reason for detention, the sentence severity, and the length of detention. …”
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ADMET evaluation in drug discovery: 21. Application and industrial validation of machine learning algorithms for Caco-2 permeability prediction by Dong Wang, Jieyu Jin, Guqin Shi, Jingxiao Bao, Zheng Wang, Shimeng Li, Peichen Pan, Dan Li, Yu Kang, Tingjun Hou

“…Matched molecular pair analysis was carried out to provide reasonable suggestions for researchers to improve the Caco-2 permeability of compounds. …”
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Impact assessment of Chinese mitten crab polyculture on saline-alkali rice fields based on food web models by Liang Yue, Shipeng Dong, Feng Liu, Dapeng Liu, Hongwei Shan, Fang Wang

“…Overall, after polyculture with Chinese mitten crabs and the addition of feed, the rice farming system’s trophic structure did not change significantly, yet more energy was directed towards production, and the current polyculture ratio is reasonable. This study not only provides scientific evidence for the development of the rice-crab integrated farming model in saline-alkali soils, but also enriches the application potential of food web modeling in integrated rice-fish farming systems.…”
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Cobalt (II) phthalocyanine derived Co3O4@HCNFs as highly effective bifunctional electrocatalysts for iodide redox couple reduction (IRR) and oxygen reduction reaction (ORR) by Ziyu Guo, Wenyu Gong, Jianing Guo, Mingxing Wu

“…Moreover, the specific hollow structure with opens at both ends is beneficial for mass diffusion to ensure sufficient contact between the electrolyte and the electrocatalysts, which is also a possible reason for the high catalytic activity of Co3O4@HCNFs. …”
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Evaluation of phosphate sources using ruminal fiber transit kinetics methodology by Claudiney de Jesus Couto, Bruna Cardoso Braga, Raphael dos Santos Gomes, Wagner Pessanha Tamy, Severino Delmar Junqueira Villela, Fernando de Paula Leonel, Fernando de Paula Leonel

“…IntroductionSince the low phosphorus content is one of the reasons for the low degradation of fiber in roughage such as pasture and by-products, fiber transit kinetics can be an important tool to evaluate differences in digestion depending on phosphorus supplementation with different sources. …”
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Exploring the impact of genetic factors and fatty acid quality on visceral and overall Fat levels in overweight and obese women: a genetic risk score study by Niloufar Rasaei, Atefeh Tavakoli, Saba Mohammadpour, Mehdi Karimi, Alireza Khadem, Azam Mohamadi, Seyedeh Fatemeh Fatemi, Fatemeh Gholami, Khadijeh Mirzaei

“…Conclusion This study shows; that eating more food sources containing a higher ratio of N6/N3 may be the reason for the increase in VAI in obese women who have high obesity-related SNPs and emphasizes the matter of personalized nutrition in obesity issues.…”
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Epidemiology and impact of device-specific infections on patients receiving left ventricular assist devices by Amit Iyengar, MD MSE, Jason Feinman, MD, Joyce Jiang, BS, Cindy Song, BA, Spencer Kim, BA, Alvin Mathew, MD, Sophia Golec, MD, Aarti Rao, MD, Ankitha Radakrishnan, MD, Michaela Asher, MPhil, David Rekhtman, BS, John DePaolo, MD PhD, Noah Moss, MD, Shinobu Itagaki, MD, Anelechi Anyanwu, MD, Joyce Wald, DO, Marisa Cevasco, MD MPH, Aditya Parikh, MD

“…LSI patients were hospitalized an extra 8 (0−28) days for infection-related reasons. Conclusion: LSIs remain pervasive, with most related to Staphylococcus, Pseudomonas, and Serratia, and are associated with significantly increased rehospitalization burden. …”
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