Variable domain mutational analysis to probe the molecular mechanisms of high viscosity of an IgG1 antibody by Jing Dai, Saeed Izadi, Jonathan Zarzar, Patrick Wu, Angela Oh, Paul J. Carter

“…Subcutaneous injection is the preferred route of administration for many antibody therapeutics for reasons that include its speed and convenience. However, the small volume limit (typically [Formula: see text]2 mL) for subcutaneous delivery often necessitates antibody formulations at high concentrations (commonly ≥100 mg/mL), which may lead to physicochemical problems. …”
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Clinical manifestations of coronary artery embolism due to heart tumors by R.M. Vitovsky, V.V. Isaіenko, O.V. Kupchinsky, I.V. Martyschenko, M.M. Serdyuk

“…In one case it was a routine examination 6 months after stenting of the coronary artery. The reason to perform echocardiography in another case was the result of electrocardiography, showing necrotic changes of the left ventricular posterior wall. …”
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Modeling suction of unsaturated granular soil treated with biochar in plant microbial fuel cell bioelectricity system by K. C. Onyelowe, Ahmed M. Ebid, Rosa Belén Ramos Jiménez, Viroon Kamchoom, M. Vishnupriyan, Krishna Prakash Arunachalam

“…The newly established model demonstrates a reasonable ability to predict SWCC and a cheaper technology in predicting the suction of unsaturated soils in relation to the studied bioelectric factors of the BPMFC. …”
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Development of Postural Control in Healthy Children: A Functional Approach by Christine Assaiante, Sophie Mallau, Sébastien Viel, Marianne Jover, Christina Schmitz

“…When studying the emergence of postural strategies, it is essential to distinguish between results that can be explained by biomechanical reasons strictly and those reflecting the maturation of the central nervous system (CNS). …”
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RETRACTED ARTICLE: Sign language recognition using the fusion of image and hand landmarks through multi-headed convolutional neural network by Refat Khan Pathan, Munmun Biswas, Suraiya Yasmin, Mayeen Uddin Khandaker, Mohammad Salman, Ahmed A. F. Youssef

“…Here, “Finger Spelling, A” dataset has been used, with 24 letters (except j and z as they contain motion). The main reason for using this dataset is that these images have a complex background with different environments and scene colors. …”
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Floor Heave Mechanism and Control Technique of Water‐Rich Soft‐Rock Roadway in Thick Coal Seam by Fulian He, Wenli Zhai, Weixin Liu, Ning Sun, Jiayu Song, Jianlong Zhang, Yanhao Wu

“…The results showed that the main reason for the serious damage to the roadway floor was the low strength of the surrounding rock of the roadway floor, and floor damage was exacerbated by the low support strength, hydraulic effects, and mining impact. …”
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Elucidation of the Inhibitory Effect of Phytochemicals with Kir6.2 Wild-Type and Mutant Models Associated in Type-1 Diabetes through Molecular Docking Approach by Manaswini Jagadeb, V Badireenath Konkimalla, Surya Narayan Rath, Rohit Pritam Das

“…Several target proteins have been identified, and the etiology causing diabetes has been reasonably well studied. But, there is still a gap in deciding on the choice of a drug, especially when the target is mutated. …”
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Research on blood donation and supply of red blood cell products to medical institutions under the spread of COVID-19 disease in Japan by Tomohide Mishiba, Shinji Takeoka

“…Although there were some fluctuations since January 2020, the amount of estimated donated whole blood, manufactured RBC products, inventory, and supply to medical institutions remained almost stable. The reasons are thought to be the contribution of registered repeaters cooperating in blood donation, the accurate prediction of supply and demand by the JRCS, the call for blood donations in accordance with the prediction, and the timely exchange of products between block centers, and the utilization of a safe supply system established previously by the JRCS. …”
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Enhancing sulfide stress cracking resistance of a Cu-bearing high strength low alloyed steel through decreasing austenitizing temperature by Tianyi Zeng, Qingzhan Zhang, Shuzhang Zhang, Yong Zhou, Yinghui Zhao, Xianbo Shi, Wei Yan

“…Without sacrificing the strength, the SSC resistance was greatly increased through decreasing the austenitizing temperature, reasons came down to less dislocations, higher HAGBs density, more recrystallized regions and finer Cr-rich carbides.…”
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Wide‐Bandgap Nickel Oxide with Tunable Acceptor Concentration for Multidimensional Power Devices by Yunwei Ma, Yuan Qin, Matthew Porter, Joseph Spencer, Zhonghao Du, Ming Xiao, Boyan Wang, Yifan Wang, Alan G. Jacobs, Han Wang, Marko Tadjer, Yuhao Zhang

“…This NA range allows for charge balance to n‐type region with reasonable process latitude, and EB is high enough to pair with many WBG and UWBG semiconductors. …”
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Study on the workability, strength, durability and environmental performance of alkali-activated electrolytic manganese slag-fly ash-slag grouting materials by Yongquan Chen, Zhonghu Wu, Chi Zeng, Yuan Liu, Shaoyun Pu, Hui Zhang, Zheng Feng, Kun Xu, Deliang Ni

“…According to the residual strength coefficient, the order of the erosion effect is as follows: NaCl solution > Na2SO4 solution > groundwater, and the main reason for the decrease in the durability performance of the samples after erosion is the dissolution of some of the hydration products and corrosion. …”
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The Gut Microbiota in Women Suffering from Gestational Diabetes Mellitus with the Failure of Glycemic Control by Lifestyle Modification by Guangyong Ye, Long Zhang, Min Wang, Yunbo Chen, Silan Gu, Keyi Wang, Jianhang Leng, Yujia Gu, Xinyou Xie

“…The combined diagnostic performance of Blautia, Eubacterium_hallii_group, and Faecalibacterium in differentiating GDM2 from GDM was considered as the most reasonable identification indicator. Gut bacteria may participate in the pathological development of GDM2 through the peroxisome proliferator-activated receptor (PPAR) signaling pathway. …”
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How to implement pairing assistance during fighting COVID-19 in China: collaborative governance between local governments under the authoritative regulation by Changwei Wei, Jiaxi Xu, Zhixiang Wang, Huangyue Wu, Juan Wang

“…The three stages of co-operative governance based on authoritative regulation work together in a step-by-step manner to enhance the effectiveness of crisis response.ConclusionThe results of the study indicate that collaborative governance under the authoritative regulation is the main reason why provincial counterpart support mechanism plays a great role in COVID-19. …”
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Cooperative game scheduling and revenue sharing strategy for virtual power plants considering scenery uncertainty by SONG Duoyang, XUE Tianliang, LI Yipu, TU Jintong, BI Yuhao, WANG Mankang

“…Finally, the example results show that the proposed method effectively improves the prediction accuracy of wind power, realizes the cooperative and complementary operation among alliances within the virtual power plant, and ensures the fairness and reasonableness of the revenue distribution among multiple subjects.…”
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Sex and authorship in global cancer research by Deborah Mukherji, Ophira Ginsburg, Grant Lewison, Richard Sullivan, Verna Vanderpuye, Winnie K W So, Miriam Mutebi, Nazik Hammad, Julie Torode, Erica Liebermann

“…More research is needed to understand the reasons behind this. Advancing diversity and equity in research leadership and authorship will be essential to address the complex challenges of cancer globally.…”
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Knowledge, Attitude, and Practice (KAP) of Radiographic Protection by Dental Undergraduate and Endodontic Postgraduate Students, General Practitioners, and Endodontists by Amal A. Almohaimede, Mohammad W. Bendahmash, Feras M. Dhafr, Abdullah F. Awwad, Ebtissam M. Al-Madi

“…More than half of the respondents agreed that dental X-ray is hazardous to health (60.79%), and 68.1% were familiar with ALARA (as low as reasonably achievable) principle. However, only 34% are familiar with the recommendations of the National Council on Radiation Protection (NCRP) and International Commission on Radiological Protection (ICRP). …”
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Incidence and Predictors of Antiretroviral Treatment Modification in HIV-Infected Adults: A Brazilian Historical Cohort from 2001 to 2010 by Letícia Penna Braga, Cássia Cristina Pinto Mendicino, Edna Afonso Reis, Ricardo Andrade Carmo, Cristiane Menezes de Pádua

“…Adverse drug reactions were the main reason for ART modification. Women (aHR = 1.62; p=0.022) and patients on protease inhibitor- (PI-) based regimens (aHR = 2.70; p<0.001) were at higher risk of ART modification.…”
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Techniques for Progressive Failure Simulation of Hard Brittle Surrounding Rockmass: Taking the URL Test Tunnel as an Example by Daning Zhong, Jianlin Chen, Hui Zhou, Xiangrong Chen, Yali Jiang, Liangquan Li, Jun Chen

“…The analysis accurately simulates the progressive failure characteristics of hard brittle surrounding rockmass under high stress, achieving the purpose of reasonably grasping the degree of damage to the surrounding rockmass, and provides technical reference and support on how to accurately simulate the failure of hard brittle surrounding rockmass using the finite discrete element method.…”
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Acquired vulnerability against EGF receptor inhibition in gastric cancer promoted by class I histone deacetylase inhibitor entinostat by Tamara Zenz, Robert Jenke, Denys Oliinyk, Sandra Noske, René Thieme, Tim Kahl, Ines Gockel, Florian Meier-Rosar, Achim Aigner, Thomas RH Büch

“…This highlights the need for the identification of underlying reasons, which may also provide the basis for possible combination therapies. …”
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A MULTICENTER STUDY OF BENIGN PROSTATIC HYPERPLASIA PATIENTS UNDERGOING TRANSURETHRAL RESECTION OF THE PROSTATE IN INDONESIA: A DESCRIPTIVE ANALYSIS by Besut Daryanto, Kurnia Penta Seputra, Paksi Satyagraha, Taufiq Nur Budaya, Fauzan Kurniawan Dhani, Deddy Rasyidan Yulizar, Marta Hendry, Andrie Rhomdhon, Yudi Ambeng, Ryan Akhmad Adhi

“…Urinary retention was the most frequent reason for patients undergoing TURP, affecting 664 patients (81.7%), followed by bladder stones, which affected 58 patients (7.1%). …”
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