Meta-analysis of nifedipine and enalapril combination therapy for hypertensive patients with coronary heart disease: A systematic review and meta-analysis by Kun Wang, Wenchao Ma, Leina Sun, Fangcheng Su

“…To analyze and assess the clinical impact of nifedipine combined with enalapril on hypertension complicated with coronary heart disease, and provide evidence for rational drug use in clinic. Methods: We employed a revised version of the Jadad scale to assess the quality of the research literature following a rigorous screening process. …”
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Computer simulation of the spatial structure of MUC 1 peptides capable of inhibiting apoptosis by N. V. Ivanisenko, I. N. Lavrik, V. A. Ivanisenko

“…It complicates significantly the rational design of potential drugs on the basis of these peptides. …”
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Stochastic production function-based assessment of the performance of climate risk management in agriculture: Methods and applications by WANG Yangjie, MAO Xiaoyan, WANG Jinxian, QIANG Hongjie

“…This study aims to address the shortcomings of existing literatures, review the application of the stochastic production function in agricultural risk assessment, and further provide rational suggestions for optimizing resource management in response to climate change. …”
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Organisational, legal and financial bases for scientific activity in higher education institutions of the Ministry of Internal Affairs of Ukraine: problems and solutions based on m... by S. O. Serbenyuk, L. S. Nadopta

“…The ideas and proposals for the introduction of new organisational and legal frameworks for scientific research in the system of the Ministry of Internal Affairs of Ukraine are an attempt to introduce a practical mechanism for the rational and most productive use of the scientific potential of departmental institutions and establishments to ensure the security of the State, protection of human rights and freedoms, combating crime, maintaining public safety and order, applying positive foreign experience in these areas, as well as the creation of innovative methods and technologies that can compete with similar achievements in the international scientific space.…”
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EXPERIENCE OF PROJECT-BASED LEARNING: AN ATTEMPT AT OBJECTIVE ANALYSIS OF RESULTS AND PROBLEMS by D. A. Trishchenko

“…The publication materials can be used by the teachers, methodologists and administrative workers of the system of professional education interested in the efficient and rational organization of educational process and the choice of the most productive methods, means and forms of vocational training of future experts.…”
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Features of the Structure of the Regulation of the Verkhovna Rada of Ukraine: Some Theoretical and Legal Aspects by Linetskyi S.

“…The optimal path is a rational and balanced combination of both approaches, ensuring the dominance of the constitutionality of all procedures at all stages of their implementation in the parliament. …”
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Osobowość ekologiczna płci - badania ankietowe by Irena Grochowska

“…If you would like to separate pro environment personality types taking into account these characteristic for boys and girls, based on the performed survey, we can present: Rational type , scientific thinker and technocrat, consumer, which is dominant in boys answers and emotional type, esthetic environmentalist which is dominant within girls answers. …”
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Wheat flour as carbon source on water quality, growth performance, hemolymph biochemical and immune parameters of Pacific white shrimp (Penaeus vannamei) juveniles in biofloc techn... by Mohammad Hossein Khanjani, Jamshid Eslami, Maurício Gustavo Coelho Emerenciano

“…The results demonstrated that by adding wheat flour to the biofloc cultivation system (under the conditions of this study) in the amount of 50–75 % of the daily feed ration, the water quality, growth performance, feed efficiency, survival rate, hemolymph biochemical, and immunity activities of P. vannamei improved.…”
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Exploration of flame characteristics of gasoline engine fuelled by gasoline-pentanol blends using combustion endoscopy by S. Kumaravel, C. G. Saravanan, M. Vikneswaran, Vallinayagam Raman, J. Sasikala, Femilda Josephin J.S., Sulaiman Ali Alharb, Arivalagan Pugazhendhi, Edwin Geo Varuvel, Haiter Lenin Allasi

“…The insights on the flame characteristics of pentanol–gasoline blends were used to rationalize the discussion on engine performance and emissions. …”
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About One Memorable Date in the History of Spain by G. I. Volkova

“…Modern state boundaries indeed are not the result of rational planning, democratic arrangements or consideration of the local population's opinion. …”
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ZnO Nanoparticle-Assisted Synthesis of Thiazolo[3,2-α]Pyrimidine Analogs: Antibacterial and Antioxidant Activity, In Silico Molecular Docking, and ADMET Prediction Study by Demis Zelelew, Milkyas Endale, Yadessa Melaku, Taye B. Demissie, Japheth O. Ombito, Rajalakshmanan Eswaramoorthy

“…The present study revealed that the synthesized compounds appear to be lead compounds for rational drug design.…”
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Comparative analysis of the performance, egg quality and ovarian immune function of fast and slow feather strains in tianfu green shell laying hens at various stages of egg product... by Zhi Hu, Hengyong Xu, Zhipeng Zhang, Yuxiang Lu, Yuxin Zhou, Jiajun Zhu, Qingqing Deng, Xi Wang, Yiping Liu, Yao Zhang, Yan Wang

“…This objective of this experiment was to compare and evaluate the performance, egg quality, and immune function of Tianfu green shell laying hens with varying feather growth rates, in order to provide a reference for their rational utilization. A total of 120 one-day-old healthy Tianfu green shell laying hens were classified into the early-feathering (EF) and late-feathering (LF) groups through phenotypic identification of feather length and qPCR molecular identification. …”
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Temporally enhanced RSEI and nighttime lights reveal long-term ecological changes and effective protection in China’s inaugural national parks by Chunhui Wen, Tengfei Long, Guojin He, Weili Jiao, Wei Jiang

“…Protected areas are vital for preserving biodiversity and ensuring ecosystem services. Rational assessments of long-term change in ecological environment quality within these areas are crucial for informing effective conservation strategies and policy decisions. …”
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Optimization of cross-sectional shape and support parameters of headgate in fully mechanized coal seam with large dip angle and close distance by Kun PAN, Wenjun JU, Junchao WANG, Housheng JIA, Biao HOU, Yinwei WANG, Zhiming ZHANG

“…This adjustment leads to a more rational overall stress distribution within the surrounding rock of the roadway, enhances the controllability of rock failure, and improves the utilization rate of the roadway cross-section. …”
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Spatio-temporal Evolution of Land Surface Temperature and Its Response to LULC in the Urban Agglomeration of Central Yunnan by LIN Zhiqiang, PENG Shuangyun, SHI Shuangfu, HUANG Bangmei, MA Dongling, ZHU Ziyi, MA Xiaoliang, GONG Luping

“…The study's results can provide important insights for rational development planning and improvement of ecological conditions in the urban agglomeration of central Yunnan.…”
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Influence of Irradiance, Flow Rate, Reactor Geometry, and Photopromoter Concentration in Mineralization Kinetics of Methane in Air and in Aqueous Solutions by Photocatalytic Membra... by Ignazio Renato Bellobono, Mauro Rossi, Andrea Testino, Franca Morazzoni, Riccardo Bianchi, Giulia de Martini, Paola Maria Tozzi, Rodica Stanescu, Cristina Costache, Liliana Bobirica, Mauro Luigi Bonardi, Flavia Groppi

“…The influence of irradiance on k1 and k2, as well as of flow rate on K1 and K2, is rationalized. The influence of reactor geometry on k values is discussed in view of standardization procedures of photocatalytic experiments. …”
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CD4 CAR-T cells targeting CD19 play a key role in exacerbating cytokine release syndrome, while maintaining long-term responses by Alice Bergamini, Barbara Camisa, Attilio Bondanza, Fabio Ciceri, Chiara Bonini, Monica Casucci, Beatrice Greco, Camilla Bove, Silvia Arcangeli, Laura Falcone, Rita El Khoury, Anna De Lucia

“…Interestingly, the combination of CD4.BBz with CD8.28z CAR-T cells resulted in the lowest toxicity, without impacting antitumor efficacy.Conclusions Taken together, these data point out that the rational design of improved adoptive T-cell therapies should consider the biological features of CD4 CAR-T cells, which emerged as crucial for maintaining long-term responses but also endowed by a higher toxic potential.…”
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Utilizing Targeted Next-Generation Sequencing for Rapid, Accurate, and Cost-Effective Pathogen Detection in Lower Respiratory Tract Infections by Qin L, Liang M, Song J, Chen P, Zhang S, Zhou Y, Li H, Tang J, Ma Y, Yang B, Xu J, Zhang J

“…Nevertheless, tNGS is faster and more cost-effective than mNGS, making it highly significant for guiding rational treatment.Keywords: targeted next-generation sequencing, metagenomic next-generation sequencing, lower respiratory tract infections, diagnosis, antibiotic treatment…”
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Rapid detection of carbapenem-resistant Escherichia coli and carbapenem-resistant Klebsiella pneumoniae in positive blood cultures via MALDI-TOF MS and tree-based machine learning... by Xiaobo Xu, Zhaofeng Wang, Erjie Lu, Tao Lin, Hengchao Du, Zhongfei Li, Jiahong Ma

“…The aim of this study was to provide rapid detection of CREC and CRKP in blood cultures, to shorten the turnaround time for laboratory reporting, and to provide a basis for early clinical intervention and rational use of antibiotics. Results The collected MALDI-TOF MS data of 640 E. coli and 444 K. pneumoniae were analysed by machine learning algorithms. …”
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Agricultural land use conflict identification and land degradation risk analysis from the perspective of spatial matching in the Ili River Valley by DONG Guanglong, WANG Jue, WANG Han, CHENG Weiya, LIU Zheng, ZHANG Wenxin

“…[Objective] This study aimed to accurately identify agricultural land use conflicts and related potential land degradation risks, and provide a scientific reference for the rational allocation of land resources, optimization of agricultural production spatial layout, and protection of healthy and sustainable agricultural development and national food security. …”
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