Ginsenoside Rg1 Improves Differentiation by Inhibiting Senescence of Human Bone Marrow Mesenchymal Stem Cell via GSK-3β and β-Catenin by Ziling Wang, Rong Jiang, Lu Wang, Xiongbin Chen, Yue Xiang, Linbo Chen, Minghe Xiao, Li Ling, Yaping Wang

“…To demonstrate the effect of Ginsenoside Rg1 on the differentiation of human bone marrow-derived mesenchymal stem cells (hBM-MSCs). Subsequently, a rational mechanism for the detection of Rg1 which affects mesenchymal stem cell differentiation was explored. …”
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An Investigation of the Enolization and Isomeric Products Distribution in the Water Promoted Aldol Reaction of Tropinone and Granatanone by Ryszard Lazny, Artur Ratkiewicz, Krzysztof Brzezinski, Aneta Nodzewska, Katarzyna Sidorowicz

“…The dependence of the anti/syn-diastereoselectivity on the amount of water used may be rationalized on the basis of change in the polarity of the reaction medium. …”
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Periodic solutions for a class of perturbed sixth-order autonomous differential equations by Chems Eddine Berrehail, Amar Makhlouf

“…,x(5)), where p and q are rational numbers different from 1, 0, −1 and p ≠ q, ε is a small enough parameter and F ∈ C2 is a nonlinear autonomous function. …”
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Development of a UPLC-MS/MS Method for the Quantification of VS-5584 and Its Application in Pharmacokinetic Studies in Rats by Chunling Zhou, Xiaoxin Li, Aiping He, Tianzhu Liu, Jinmiao Tian, Meihua Jiang, Lina Fang

“…VS-5584 is a small-molecular compound that showed equivalent activity against mTOR and all class I PI3K isoforms and demonstrated preclinical activity in diverse cancer cell lines and xenograft tumor model, and rational combination of VS-5584 and other target therapies achieved promising outcomes in oncology. …”
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Electron‐Lattice Synergistic Coordination for Boosting the Electro‐Optic Response of the Crystal by Jinfeng Han, Yuzhou Wang, Fei Liang, Kui Wu, Dazhi Lu, Deliang Cui, Haohai Yu, Huaijin Zhang

“…Here, an electron‐lattice synergistic coordination strategy is proposed for boosting the E‐O response, and with the langasite as the subject, a novel crystal La3Zr0.5Ga5Si0.5O14 (LZGS) is designed. By the rational introduction of the Zr4+ ion in the octahedral site, it is found that the E‐O response can be obviously improved attributed to the active 4d orbitals of the Zr4+ ion and the optical phonons of the flexible (ZrO6) unit. …”
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Performance of the Cold-Bending Channel-Angle Buckling-Restrained Brace under Cyclic Loading by Kun Wang, Junwu Xia, Xiaomiao Chen, Bo Xu, Xiangzhou Liang, Jian Wang

“…Finally, all the tested CCA-BRBs exhibited a stable energy absorption performance and verified the specimens’ construction was rational.…”
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Designing the trajectories of variant teaching of the basics of artificial intelligence in the school course of computer science taking into account the possibilities of project-re... by Sergey D. Karakozov, Nadezhda N. Samylkina

“…On the basis of the proposed components of the methodology of teaching artificial intelligence basics and data analysis, the possibilities of designing different learning trajectories in accordance with personal requests of participants of educational relations, as well as for the rational use of resources of the information educational environment of the organization in the implementation of basic educational programs of general education are shown. …”
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Hierarchical Clustering of Residential Appliances Considering the Characteristics of the Appliances by Shima Simsar, Mahmood Alborzi, Ali Rajabzadeh Ghatari, Ali Yazdian

“…Based on the results, it was found that the proposed clustering method can rationally classify different types of home appliances by selecting the appropriate characteristics since the appliances in a cluster are very similar to each other and can help users understand the operating conditions of the appliances.…”
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Tailoring IPM plans to fight a cloaked pest: helping smallholder farmers combat the sweetpotato weevil in sub-Saharan Africa by Chad A. Keyser, Frederick S. Walters, Haley Turner, Elka Armstrong, Jeff Davis, Brooke Bissinger, Brant Johnson, Agnes Alajo, Paul Musana, Joseph Odongo, Benard Yada, Milton A. Otema

“…In this paper we, (1) outline factors that contribute to SPW infestation; (2) review available strategies and ongoing research for control of SPW, including chemical pesticides, biological control (macro-organismal as well as microbial control), cultural practices, selective breeding, and biotechnology; and (3) discuss the potential for implementing an integrated pest management (IPM) approach that leverages a combination of techniques. We rationalize that a multifaceted strategy for SPW control will improve both the quantity and quality of sweetpotato production in Africa.…”
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Advancing the utilization of 2D materials for electrocatalytic seawater splitting by Shemsu Ligani Fereja, Andleeb Mehmood, Qianqian Ji, Waseem Raza, Ahmed Hussen, Jie Hu, Shuo Zhai, Xingke Cai

“…This review provides valuable insights for the rational design and development of cutting‐edge 2D material electrocatalysts for seawater‐electrolysis applications.…”
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THE ROLE OF CROWDFUNDING IN THE FUTURE OF UKRAINE: PROBLEMS AND PROSPECTS by Natalia Grebeniuk, Mariana Shvayko, Kateryna Tykhomyrova

“…The purpose of writing the article is to find alternative sources of funding for resto­ration projects, forecasting the impact of their implementation on the state of Ukraine's economy. …”
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Application of Extrapolation Capability of Vector Fitting for Out-of-Band Dominant Modal Synthesis of Voltage-Source Converters by Weihua Zhou, Jef Beerten

“…This article presents, for the first time, the potential identification of several critical out-of-band modes of an artificially created rational function and a grid-connected VSC. This identification is achieved through their band-limited frequency responses using the vector fitting (VF) algorithm. …”
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Curcumin dietary supplementation enhances serum carbohydrate-degrading enzyme activities in buffaloes by Maima Matin, Natalia Ksepka, Kamil Wysocki, Michel-Edwar Mickael, Alpana Pande, Jarosław Olav Horbańczuk, Artur Jóźwik, Olga Adamska, Artur Stolarczyk, Laszlo Barna Iantovics, Yordanka Ilieva, Pencho Penchev, Atanas G. Atanasov

“…These upregulated activities are in general indicative of increased carbohydrates turnover and detoxification processes, and might provide clues for a better understanding of the mechanisms of action of curcumin in vivo, as well as for novel approaches to rationally impact animal or human health and wellbeing through targeted supplementation.…”
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Post-mortem and histological lesions in the European minks (Mustela lutreola) induced by spontaneous infection with coronavirus SARS-CoV-2 by I. A. Subbotina, I. N. Gromov

“…All this together will allow veterinary specialists not only to quickly and timely diagnose the disease in the population of fur animals (European mink), but also to take necessary therapeutic and preventive measures in a timely manner, to select the most effective means for symptomatic and pathogenetic therapy as well as the most rational and effective substances and disinfection procedures.…”
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Hydrogeochemical characteristics and environmental significance of travertine landscape in Muji area by Rui AN, Miao SUN, Yiwei ZHANG, Bin LI, Wenpeng LI, Kun LIU

“…Based on the need for the protection of travertine landscape and human drinking water safety, our results are of great significance for understanding the characteristics of hydrochemical environment shaped by travertine landscape, effective protection, and rational use of groundwater in karst areas.…”
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Lipoprotein Signal Peptide as Adjuvants: Leveraging Lipobox-Driven TLR2 Activation in Modern Vaccine Design by Muhammad Umar, Haroon Afzal, Asad Murtaza, Li-Ting Cheng

“…Recent advances in bioinformatics have significantly improved the prediction of SP structures and cleavage sites, facilitating the rational design of recombinant lipoproteins optimized for immune activation. …”
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Study on the Composite Performance of Sandwich Wall Panels with SGCCs by Huanzhi Jiang, Libo Xie, Fengyuan Chang, Yu Cao, Zhengxing Guo

“…This study provides theoretical and data support for the rational configuration of connectors in sandwich wall panels and is of great significance for building engineering applications. …”
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Comprehensive evaluation and attribution analysis of baseflow variation in a typical karst basin, Southwest China by Chongxun Mo, Changhao Jiang, Shiting Long, Weiyan Cen

“…An adaptive baseflow research system for karst basins was established in this study, including the application of nine baseflow separation methods to reduce uncertainty in baseflow simulations, a more rational determination of annual and intra-annual baseflow characteristics, and an assessment of the impacts of climate change and human activities combining key meteorological elements and socio-economic indicators through the double-mass curve and SCRCQ methods. …”
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Alternations in Cholesterol and Fatty Acids Composition in Egg Yolk of Rhode Island Red x Fyoumi Hens Fed with Hemp Seeds (Cannabis sativa L.) by Suhaib Shahid, Naila Chand, Rifat Ullah Khan, Syed Muhammad Suhail, Nazir Ahmad Khan

“…HS was included into the ration at the level of 0.0 (HS-0), 15 (HS-15), 20 (HS-20), and 25% (HS-25) and continued the supplementation for consecutively three weeks. …”
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New derivatives of sulfonylhydrazone as potential antitumor agents: Design, synthesis and cheminformatics evaluation by Sabbah Dima A., Al-Azaideh Bara’a A., Talib Wamidh H., Hajjo Rima, Sweidan Kamal, Al-Zuheiri Aya M., Sheikha Ghassan Abu, Shraim Sawsan

“…Hence, our results emphasized the importance of electron-withdrawing groups and hydrogen bond-acceptors in the rational design of small-molecule chemical ligands targeting PI3Kα. …”
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