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1581
New derivatives of sulfonylhydrazone as potential antitumor agents: Design, synthesis and cheminformatics evaluation
Published 2021-12-01“…Hence, our results emphasized the importance of electron-withdrawing groups and hydrogen bond-acceptors in the rational design of small-molecule chemical ligands targeting PI3Kα. …”
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1582
Medication use and potential drug-drug interactions in a general surgery clinic: A descriptive studyMain points
Published 2025-02-01“…We suspect that the elevated number of medications administered postoperatively could have led to pDDIs Consequently, we expect that clinical pharmacy services will help ensure the safe and rational use of medications in surgical clinics.…”
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1583
Assessment of the Logical Prescription of Albumin Drug According to Guideline and Patient Safety for Inpatients in Intensive Care Units of Iranian Hospital: A Cross-Sectional Study
Published 2024-10-01“…Conclusion: The research highlights the importance of continuous guideline-base DUE on rational drug utilization, patient safety and hospitals costs. …”
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1584
Hot corrosion resistance of AlCoCrFeNi2.1 coatings at 900 °C
Published 2025-03-01“…Therefore, in high-temperature corrosion environments, the rational design and control of residual compressive stress provide an effective approach to improving the hot corrosion resistance of AlCoCrFeNi2.1 EHEA coatings.…”
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1585
Development and validation of the Chinese Rural Middle-aged and Elderly Health Literacy Scale
Published 2024-04-01“…Third, pretesting was used to assess the rationality of the item settings within the CREHLS. …”
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1586
Complex congenital heart and lung defects as a cause of hydrops fetalis in French bulldogs –micro-CT with contrast study
Published 2025-02-01“…Examination of the heart in conjunction with the lungs appears to be a rational approach in animals with hydrops fetalis.…”
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1587
Aggregation‐induced circularly polarized luminescence and delayed fluorescence enabled by activating high‐level reverse intersystem crossing
Published 2025-01-01“…However, much effort has been normally focused on the utilization of T1 excitons but seldom on the utilization of higher excited triplet state Tn (n > 1) excitons. Rational manipulation of higher excited triplet state Tn (n > 1) excitons and suppression of Kasha's rule of CPL materials remains a major challenge. …”
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1588
Dioxin Control in the Co-processing of Waste Printed Circuit Board and Copper Concentrate with an Ausmelt Furnace
Published 2023-10-01“…These findings will facilitate the rational control of dioxin emissions with the co-processing of WPCB in an Ausmelt furnace.…”
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1589
Numerical Simulation of Nanosilica Sol Grouting for Deep Tunnels Based on the Multifield Coupling Mechanism
Published 2021-01-01“…The effect characteristics of grouting pressure and initial permeability are clarified. The rationality of this model is verified by classical Newtonian fluid grouting theory. …”
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1590
A generalized interval-valued p,q Rung orthopair fuzzy Maclaurin symmetric mean and modified regret theory based sustainable supplier selection method
Published 2024-06-01“…We also provide sensitivity analysis and comparative analysis to further demonstrate the rationality and validity of the proposed method.…”
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1591
Degradation dynamics of Trifluralin in Qinghai-Tibet Plateau and screening of its degrading strains
Published 2025-01-01“…The findings of this study provide important data for the environmental risk assessment of FLL and suggest potential biological resources for the rational use and environmental remediation of this herbicide. …”
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1592
Structural comparison of human and Plasmodium proteasome β5 subunits: informing selective inhibitor design for anti-malaria agents
Published 2025-01-01“…This study contributes valuable insights into the structural basis for targeting the Plasmodium proteasome and paves the way for the rational design of compounds with enhanced specificity and efficacy against malaria.…”
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1593
Structural Analysis of Inhibitor Binding to Enterovirus-D68 3C Protease
Published 2025-01-01“…This structural analysis combined with enzymatic assays provides insights for the rational design of inhibitors that are robust against resistance toward developing antiviral treatments for EV68 infections.…”
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1594
A compliant metastructure design with reconfigurability up to six degrees of freedom
Published 2025-01-01“…These devices incorporate passive flexures and actively stiffness-changing rods to modify kinematic freedom. A rational design pipeline informs the flexures’ topological arrangements, geometric parameters, and control signals based on targeted mobilities, enabling the creation of unitary joints with up to six degrees of freedom. …”
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1595
An Improved Numerical Model of Shield Tunnel with Double Lining and Its Applications
Published 2015-01-01“…Based on the existing numerical models of shield tunnel with double lining, an improved numerical model is developed and its rationality is verified by a similar model test. In the improved numerical model, lining, joint, and junction surface, respectively, are simulated by beam, spring, and a combination of compression bar and spring. …”
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1596
A Novel Method for Predicting Urban Residential Quality Distribution Based on Multi-Interest Consideration
Published 2025-01-01“…Given limited resources, understanding how to improve urban residential quality and rationally plan the distribution of different quality levels warrants further study. …”
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1597
A dendritic hexamer acceptor enables 19.4% efficiency with exceptional stability in organic solar cells
Published 2025-01-01“…Abstract To achieve the commercialization of organic solar cells (OSCs), it is crucial not only to enhance power conversion efficiency (PCE) but also to improve device stability through rational molecular design. Recently emerging giant molecular acceptor (GMA) materials offer various advantages, such as precise chemical structure, high molecular weight (beneficial to film stability under several external stress), and impressive device efficiency, making them a promising candidate. …”
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1598
HISTORY AND RESULTS OF THE INTRODUCTION OF PALMS (ARECACEAE C.H. SCHULTZ) ON THE SOUTHERN COAST OF THE CRIMEA
Published 2018-09-01“…Recommendations as to agricultural practices, protection in winter, and rational utilization of palms in ornamental gardening have been provided.…”
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1599
The relationship between relative deprivation and fear of missing out in college students: the role of self-regulatory fatigue and personal belief in a just world
Published 2025-01-01“…The results also show that reducing college students’ RD, improving self-control ability, and cultivating rational personal BJW can effectively prevent FoMO.…”
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1600
A spatiotemporal distribution prediction model for electric vehicles charging load in transportation power coupled network
Published 2025-02-01“…This study represents a reliable approach for predicting charging demand in a certain region, and also provides powerful support for the rational planning of EV charging stations.…”
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