Polymorphism of renin — angiotensin system genes in progression of liver fibrosis in patients with chronic hepatitis C by O. V. Taratina, T. N. Krasnova, L. M. Samokhodskaya, T. N. Lopatkina, V. A. Tkachuk, N. A. Mukhin

“…As chronic hepatitis C is multifactorial disease, it is rational to use testing of allelic variants of angiotensinogen gene in patient-specific approach at CHC management.…”
Get full text

The structural characteristics of dietary fibers from Tremella fuciformis and their hypolipidemic effects in mice by Shanshan Zhang, Xinle Xu, Xu Cao, Tingting Liu

“…These results provide a reference for further research and rational development of T. fuciformis.…”
Get full text

Preoperative chemotherapy usage experience for intrahepatic cholangiocarcinoma by A. N. Polyakov, D. A. Granov, Yu. I. Patyutko, I. A. Pokataev, A. A. Polikarpov, T. I. Kagacheva, I. S. Bazin, A. Sh. Umirzokov, D. Yu. Frantsev, V. N. Zhuikov, D. V. Podluzhny

“…Randomized trials are necessary to determine the rationality, as well as the type and regimen of preoperative therapy to be used in patients with IHCC.…”
Get full text

A Reliable Medium for Monitoring Atmospheric Deposition near Emission Sources by Using Snow from Agricultural Areas by Jiayang Liu, Zaijin Sun, Wenkai Lei, Jingwen Xu, Qian Sun, Zhicheng Shen, Yixuan Lyu, Huading Shi, Ying Zhou, Lan Zhang, Zefeng Wu, Yuepeng Pan

“…To investigate the rationality of this method, 52 snow samples were collected from sites surrounding smelting plants in Anyang, an industrial region of North China. …”
Get full text

mtlA, a novel typing gene offering enhanced resolution for pandemic Vibrio species by Lei Zhou, Danlei Liu, Zilong Zhang, Yongqiang Zhu, Huajun Zheng

“…Therefore, based on the prevalent characteristics of pathogenic Vibrio, it is imperative for us to classify and trace various Vibrio species that cause human illness and prescribe medication rationally to control the spread of diseases. In our investigation, we explored the prevalence and typing accuracy of the mtlA gene in Vibrio. …”
Get full text

Preoperative CT-based radiomics nomogram to predict the micropapillary pattern in lung adenocarcinoma of size 2 cm or less by Xiaoyu Pan, Liang Fu, Jiecai Lv, Lijuan Feng, Kai Li, Siqi Chen, Xi Deng, Liling Long

“…DCA confirmed that the nomogram model had the better clinical benefit.ConclusionsThe nomogram model achieved promising prediction efficiency for identifying the presence of the MPP in LUAD tumors ≤2 cm, allowing clinicians to develop more rational and efficacious personalized treatment strategies.…”
Get full text

Construction of a novel radioresistance-related signature for prediction of prognosis, immune microenvironment and anti-tumour drug sensitivity in non-small cell lung cancer by Yanliang Chen, Chan Zhou, Xiaoqiao Zhang, Min Chen, Meifang Wang, Lisha Zhang, Yanhui Chen, Litao Huang, Junjun Sun, Dandan Wang, Yong Chen

“…Its clinical routine use may assist clinicians in selecting more rational practices for individuals, which is important for improving the prognosis of NSCLC patients. …”
Get full text

Efficacy of Fat Supplements with Different Unsaturated/Saturated FA Ratios Undergoing First Postpartum Ovulation in Lactating Anovulatory Goats by Caroline P. Silva, César C. L. Fernandes, Juliana P. M. Alves, Camila M. Cavalcanti, Felipe B. B. Oliveira, Alfredo J. H. Conde, Diana Celia S. N. Pinheiro, Darcio I. A. Teixeira, Anibal C. Rego, Davide Rondina

“…Thirty-eight An-glo-Nubian-crossbred adult goats were allocated into three groups, one with a control diet (<i>n</i> = 12), fed a total mixed ration (TMR) comprising chopped elephant grass and concentrate; an algal diet (<i>n</i> = 13), fed TMR + green microalgae (1% dry matter); and a linseed diet (<i>n</i> = 13), TMR + linseed (12% dry matter). …”
Get full text

Development of indicators and analysis of barriers for assessment and prevention of cutaneous graft-versus-host disease after haematopoietic stem cell transplantation in children by YANG Liling, ZHAN Sha, XUE Xiaoyan, CHEN Kai, LIU Qing, WANG Li, WANG Yiyi, WU Meng, LU Qunfeng

“…The main obstacles were the lack of relevant training and the absence of a rational management mechanism. The main facilitating factors were reliable sources of evidence and a high level of cooperation from potential stakeholders. …”
Get full text

Optimizing the Production of Polysaccharides from Cyanobacterium sp. IPPAS B-1200 by Stanislav A. Sukhikh, Ekaterina A. Budenkova, Yulia-Danae S. Boychenko, Veronika D. Anokhova, Vyacheslav F. Dolganyuk, Egor V. Kashirskih

“…For freeze drying, the rational parameters were 8 h at –15°C.…”
Get full text

Diagnostics and treatment of Clostridium difficile-associated disease: Guidelines of the Russian gastroenterological association by V. T. Ivashkin, N. D. Yushchuk, I. V. Mayev, Tatyana L Lapina, Ye. A. Poluektova, O. S. Shifrin, A. S. Tertychny, A. S. Trukhmanov, A. A. Sheptulin, Ye. K. Baranskaya, O. S. Lyashenko, K. V. Ivashkin

“…Prophylaxis requires rational application of antibiotics, decrease, whenever possible, of terms of hospital stay, timely diagnosis and observance of sanitary and epidemiologic rules in medical institutions. …”
Get full text

How Do the Four Core Factors of High Entropy Affect the Electrochemical Properties of Energy‐Storage Materials? by Wenze Wang, Qian Zhang, Liting Yang, Guisheng Liang, Xuhui Xiong, Yifeng Cheng, Limin Wu, Chunfu Lin, Renchao Che

“…The insight gained here can provide a guide for the rational design of new HEMs with good energy‐storage properties.…”
Get full text

Effects of Different Nitrogen Fertilizer Application Rates on Soil Microbial Structure in Paddy Soil When Combined with Rice Straw Return by Xiannan Zeng, Qi Wang, Qiulai Song, Quanxi Liang, Yu Sun, Fuqiang Song

“…This experiment provides technical support for the application of the alternative fertilizer technology of straw return to the field and provides a theoretical basis for rational fertilization of paddy fields in a cold climate.…”
Get full text

Efficient recovery of rare metal lanthanum from water by MOF-modified biochar: DFT calculation and dynamic adsorption by Qilan Huang, Qianru Zhang, Shuwen Zhao, Chuchen Zhang, Huixin Guan, Jianqiao Liu

“…Density functional theory (DFT) computations allowed for rationally constructing the adsorption model. According to DFT calculations, the primary processes involved in the adsorption of La3+ were π–π interaction and ligand exchange, wherein the surface hydroxyl group played a crucial role. …”
Get full text

Structure of Spatial Correlation Network and Influencing Factors of Urban-Rural Integration in China by Wang Kai, Liu Meilun, Tan Jiaxin, Gan Chang

“…In practice, optimizing interprovincial urban-rural interaction and promoting cross-regional urban-rural integration development in a scientific and rational way are highly significant.…”
Get full text

Opportunities for Prevention of Complications in Intestinal Stoma Surgery by V. S. Groshilin, V. D. Kuznetsov, D. V. Kuznetsov, A. A. Pogosyan

“…In group 1 (n = 25) the developed therapeutic and diagnostic algorithm was applied, which included a rational choice of the colostomy localization site, taking into account individual features of the anterior abdominal wall structure, the quality of vascularity of the ostomy intestine, the terminal portion of its mesentery, the length and topography of the end section. …”
Get full text

Identification and characterization of the functional tetrameric UDP-glucose pyrophosphorylase from Klebsiella pneumoniae by Isabel Ramón Roth, Pavel Kats, Timm Fiebig, Françoise Routier, Roman Fedorov, Larissa Dirr, Jana I. Führing

“…UGPs have, therefore, gained attention as anti-bacterial drug target candidates, prompting us to study their structure-function relationships to provide a basis for the rational development of specific inhibitors. UGP function is tied to its oligomeric state, and the majority of bacterial homologs have been described as tetramers encoded by the galU gene. …”
Get full text

Integrated technique of buffalo fertility management in Nepal by Bhuminand Devkota, Shatrughan Shah, Gokarna Gautam

“…Putting together all those information, we developed an integrated technique of buffalo fertility management that includes anthelmintic treatment at least one month prior to the initiation of specific timed artificial insemination (TAI) protocol and nutritional management by means of providing vitamin–mineral supplementation in addition to improving the roughage supply and energy-protein content in the ration soon after anthelmintic treatment until two weeks after AI. …”
Get full text

An Integrated Stacking Ensemble Model for Natural Gas Purchase Prediction Incorporating Multiple Features by Junjie Wang, Lei Jiang, Le Zhang, Yaqi Liu, Qihong Yu, Yuheng Bu

“…It not only facilitates the rational allocation of resources for companies but also helps to reduce operational costs. …”
Get full text

Frequencies and ethnic distribution of ABO and RhD blood groups in China: a population-based cross-sectional study by Min Liu, Jue Liu, Shikun Zhang, Qiaomei Wang, Haiping Shen, Yiping Zhang

“…The diversity in the distribution of the ABO and RhD blood groups in different ethnic groups should be considered when developing rational and evidence-based strategies for blood collection and management.…”
Get full text