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  1. 2641

    Processes of salt slag recycling in aluminum production to obtain powder material with a high content of aluminum oxide phases by B. M. Nemenenok, I. V. Rafalski, P. E. Lushchik, L. P. Dolgi, A. D. Rulenkov

    Published 2023-01-01
    “…It is reported that water‑soluble fluorine compounds, such as Na3AlF6, CaF2, MgF2, K2ZrF6 , in the composition of refining fluxes complicates the processing of aluminum slags, which involve leaching of salts by water. A rational solution seems to be the replacement of sparingly soluble salts in refining fluxes with sodium or potassium fluorides with a higher solubility in water. …”
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  2. 2642

    Machine learning and genetic algorithm-guided directed evolution for the development of antimicrobial peptides by Heqian Zhang, Yihan Wang, Yanran Zhu, Pengtao Huang, Qiandi Gao, Xiaojie Li, Zhaoying Chen, Yu Liu, Jiakun Jiang, Yuan Gao, Jiaquan Huang, Zhiwei Qin

    Published 2025-02-01
    “…Conclusions: The findings of this study pave the way for the rational drug design of activity-enhanced peptide antibiotics.…”
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  3. 2643

    Design of an equilibrative nucleoside transporter subtype 1 inhibitor for pain relief by Nicholas J. Wright, Yutaka Matsuoka, Hyeri Park, Wei He, Caroline G. Webster, Kenta Furutani, Justin G. Fedor, Aidan McGinnis, Yiquan Zhao, Ouyang Chen, Sangsu Bang, Ping Fan, Ivan Spasojevic, Jiyong Hong, Ru-Rong Ji, Seok-Yong Lee

    Published 2024-12-01
    “…Our studies reveal ENT1 as a therapeutic target for analgesia, highlighting the promise of rationally designed ENT1 inhibitors for non-opioid pain medications.…”
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  4. 2644

    Different Metabolites in the Roots, Seeds, and Leaves of Acanthopanax senticosus and Their Role in Alleviating Oxidative Stress by Jie Su, Qi Wang, Zhifeng Li, Yan Feng, Yan Li, Shinlin Yang, Yulin Feng

    Published 2021-01-01
    “…The results of this study reveal the distribution characteristics and the antioxidant activity of different metabolites of A. senticosus and provide a reference for the rational development of its medicinal parts.…”
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  5. 2645

    Pharmacokinetics of Eight Flavonoids in Rats Assayed by UPLC-MS/MS after Oral Administration of Drynariae rhizoma Extract by Zhan-Ling Xu, Ming-Yue Xu, Hai-Tao Wang, Qing-Xuan Xu, Ming-Yang Liu, Chun-Peng Jia, Fang Geng, Ning Zhang

    Published 2018-01-01
    “…In order to make good and rational use of Drynariae rhizoma in future, a rapid, sensitive, and selective ultraperformance liquid chromatography-mass spectrometry (UPLC-MS/MS) method was developed to investigate the pharmacokinetics of eight main flavonoids in rat plasma after oral administration of the Drynariae rhizoma extract, including neoeriocitrin, luteolin-7-O-β-D-glucoside, astragalin, naringin, eriodictyol, luteolin, naringenin, and kaempferol. …”
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  6. 2646

    Chemical compatibility at the interface of garnet-type Ga-LLZO solid electrolyte and high-energy Li-rich layered oxide cathode for all-solid-state batteries by Natalia B. Timusheva, Alexander A. Golubnichiy, Anatolii V. Morozov, Arseniy S. Burov, Dmitry A. Aksyonov, Aleksandra A. Savina, Roman G. Markopolskii, Artem M. Abakumov

    Published 2025-01-01
    “…Li2ZrO3 was discovered for the first time as a reaction product, and its formation in the case of Li-rich layered cathode material was rationalized with DFT + U calculations. The results were also compared with those obtained for a typical layered high-energy-density cathode material LiNi0.8Mn0.1Co0.1O2 (NMC811).…”
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  7. 2647

    Direct-supply chilled-water radiant-floor cooling system coupled with an earth‒air heat exchanger system: A case study in a building by Jiaming Yang, Huiqing Cao, Zhenwei Wang, Yue Liu, Wei Song, Jiankai Dong

    Published 2025-01-01
    “…This study provides rational support for a building cooling model in which a DS-RFC system coupled with an EAHE system is supplied directly by shallow geothermal energy in summer.…”
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  8. 2648

    Role of the hospital pharmacists during COVID-19 pandemic in the RN Macedonia by Zorica Naumovska, Biljana Lazarova, Maja Kovaceva, Aleksandra Kapedanovska Nestorovska, Maja Simonoska Crcarevska, Evgenija Mihajloska, Aleksandar Dimkovski

    Published 2024-12-01
    “…The study confirmed the vital role of hospital in promoting of rational antibiotic use and antimicrobial resistance programs. …”
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  9. 2649

    Cockpit-Llama: Driver Intent Prediction in Intelligent Cockpit via Large Language Model by Yi Chen, Chengzhe Li, Qirui Yuan, Jinyu Li, Yuze Fan, Xiaojun Ge, Yun Li, Fei Gao, Rui Zhao

    Published 2024-12-01
    “…To improve the accuracy and rationality of Cockpit-Llama’s predictions, we construct a new multi-attribute cockpit dataset that includes extensive historical interactions and multi-attribute states, such as driver emotional states, driving activity scenarios, vehicle motion states, body states and external environment, to support the fine-tuning of Cockpit-Llama. …”
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  10. 2650

    Bearing Behavior of H-Shaped Honeycombed Steel Web Composite Columns with Rectangular Concrete-Filled Steel Tube Flanges under Eccentrical Compression Load by Jing Ji, Chenyu Yu, Liangqin Jiang, Jiedong Zhan, Hongguo Ren, Sixue Hao, Shaojie Fan, Li Jiang, Yubo Lin, Lingjie He

    Published 2022-01-01
    “…By comparison with the existing test results, the rationality of the constitutive model of materials and FE modeling was verified. …”
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  11. 2651

    Resistance of barley cultivars approved for use in Russia to harmful organisms and toxic aluminum ions by R. A. Abdullaev, B. A. Batasheva, N. V. Alpatieva, M. A. Chumakov, E. E. Radchenko, O. N. Kovaleva, O. V. Yakovleva

    Published 2020-10-01
    “…Background. The most rational way to reduce barley crop losses from diseases, pests and adverse edaphic factors is cultivation of resistant varieties. …”
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  12. 2652

    Ultrasonication-assisted lipase-catalyzed esterification of chlorogenic acid: A comparative study using fatty alcohol and acids in solvent and solvent-free conditions by Chia-Hung Kuo, Parushi Nargotra, Tsung-Han Lin, Chwen-Jen Shieh, Yung-Chuan Liu

    Published 2025-02-01
    “…Catalytic factors such as reaction time (12 h ∼ 36 h), enzyme dosage (10 ∼ 50 mg), and ultrasonication power (90 ∼ 150 W) were optimized using Box-Behnken design (BBD) while temperature (60 ℃) and molar ration (chlorogenic acid/octanol, 1:500) were kept constant. …”
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  13. 2653

    Reforming public service of Republic of Kazakhstan as necessary condition for effective development of national economy by S. S. Dontsov, A. S. Kadyrova, S. A. Rakhimova, A. A. Nurgaliyeva, A. A. Titkov

    Published 2020-12-01
    “…The article emphasizes the importance of rational reforms of the public service in Kazakhstan for the successful implementation of all major strategic plans and effective development of the national economy as a whole. …”
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  14. 2654

    Practice of quality control circle activities to reduce the errors in rechecking of finished drug products in pharmacy intravenous admixture service (降低静脉用药调配中心成品复核差错发生率的品管圈实践)... by CHEN Wenwen (陈雯雯), FAN Ningning (樊宁宁), XU Yuanle (许远乐), PANG Mi (庞咪), ZHOU Qing (周青), SHI Yali (石雅莉)

    Published 2023-12-01
    “…It helps to ensure the patient safety and promoting the rational drug use in clinical settings. (目的 探讨品管圈活动降低静脉用药调配中心成品复核差错发生率的效果。…”
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  15. 2655

    Fall risk-increasing drugs and associated health outcomes among community-dwelling older patients: A cross-sectional study in Croatian cohort of the EuroAgeism H2020 project by Paar Elizabeta, De Lai Eleonora, Držaić Margita, Kummer Ingrid, Bužančić Iva, Hadžiabdić Maja Ortner, Brkic Jovana, Fialová Daniela

    Published 2024-12-01
    “…Our study highlights the need for rationalization of FRID use. To reduce the unnecessary exposure to FRIDs in older adults, health-care professionals must consider high individualization of medication schemes regarding selection, dosing, and combinations of only necessary FRIDs.…”
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  16. 2656

    Chinese Medicine Huzhen Tongfeng Formula Effectively Attenuates Gouty Arthritis by Inhibiting Arachidonic Acid Metabolism and Inflammatory Mediators by Jianping Deng, Zicong Wu, Chen Chen, Zhenling Zhao, Yifei Li, Zhengquan Su, Yiguang Lin, Yifei Wang, Zhiping Wang

    Published 2020-01-01
    “…These findings extend our understanding of the pharmacological action of HZTF, rationalizing the application HZTF as an effective herbal therapy for GA.…”
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    Article
  17. 2657

    Genotyping Genebank Collections: Strategic Approaches and Considerations for Optimal Collection Management by Noelle L. Anglin, Peter Wenzl, Vania Azevedo, Charlotte Lusty, David Ellis, Dongying Gao

    Published 2025-01-01
    “…Data from genotyping can help define genetic diversity within a collection, identify genetic gaps, reveal genetic redundancies and verify uniqueness, enable the comparison of collections of the same crop across genebanks (rationalization), and determine errors or mix-ups in genetic identity that may have occurred in a germplasm collection. …”
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  18. 2658

    Opposite outcomes of triglyceride-glucose index and associated cardiovascular mortality risk in type 2 diabetes mellitus participants by different obesity criteria by Hui Huang, Jing Tian, Jiahui Xu, Qingguang Chen, Mengjie Cai, Hao Lu, Fan Gong

    Published 2025-01-01
    “…Among non-obese T2DM participants (BMI-defined), the hazard ration for CVD mortality was 1.73 in the fourth quartile group of TyG index compared with the first quartile group. …”
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  19. 2659

    Uncovering the Mechanism of Action of Antiprotozoal Agents: A Survey on Photoaffinity Labeling Strategy by Alessandro Giraudo, Cristiano Bolchi, Marco Pallavicini, Roberto Di Santo, Roberta Costi, Francesco Saccoliti

    Published 2024-12-01
    “…Besides highlighting new potential drug targets, PAL can provide valuable information on efficacy and liabilities of small molecules at the molecular level, which could be exploited to greatly facilitate the rational optimization of compounds in terms of potency and safety. …”
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  20. 2660

    An Enhanced End-to-End Object Detector for Drone Aerial Imagery by Quan Yu, Qiang Tong, Lin Miao, Lin Qi, Xiulei Liu

    Published 2025-01-01
    “…Look Forward Stage introduces a more rational gradient structure which eliminates inter-layer information bias between decoders. …”
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