Natural Cyclic Peptides: Synthetic Strategies and Biomedical Applications by Devan Buchanan, Shogo Mori, Ahmed Chadli, Siva S. Panda

“…Emerging trends, including integrating computational tools for rational design, novel cyclization techniques to improve pharmacokinetic profiles, and interdisciplinary collaboration among chemists, biologists, and computational scientists, promise to expand the scope of cyclic peptide-based therapeutics. …”
Get full text

CONTACT STRENGTH ANALYSIS OF FINGER SEAL CONSIDERING THERMAL EFFECT by ZHANG YanChao, JIAO Dandan, WU LuJi, ZHAO Rui, CUI YaHui, RAN BaoChun, WANG Wei

“…The performance test results show that,the maximum error between theoretical and test result is only 16.5% under pressure of 0.4 MPa,while the maximum error reaches 72.8% when thermal effect is not considered,which verified the necessity of thermal effect and the rationality of thermal analysis method. So the study provides an important reference for the design of finger seal under high temperature and high speed conditions.…”
Get full text

Emotions as Self-Organizational Factors of Anthropogenesis, Noogenesis and Sociogenesis by І. M. Hoian, V. P. Budz

“…It was outlined that noogenesis has an emotional dimension, because emotions are the basis for self-organization of rationality, which begins at the level of emotional consciousness. …”
Get full text

Estimating the Climate-Controlled Soil Parameters and the Distorted Mound Shape for Analysis of Stiffened Rafts on Expansive Soils by Mohamed H. Abu-Ali, Basuony El-Garhy, Ahmed Boraey, Wael S. Al-Rashed, Hassan Abdel-Daiem

“…This study presents a rational method for estimating the climate-controlled soil parameters that are used for estimating the 3D distorted mound shape of the expansive soil from the routine geotechnical tests’ results. …”
Get full text

FORMALIZATION OF THE CULTURAL HERITAGE MANAGEMENT MODEL AS A FACTOR OF TOURISM DEVELOPMENT IN THE RUSSIAN FEDERATION by Ernest E. Ibragimov, Ibraim E. Avdil’

“…The preservation of cultural heritage and its rational use have a key role and importance for attracting tourist flows and improving socio-economic indicators and sustainable development of the region. …”
Get full text

Very Short-Term Blackout Prediction for Grid-Tied PV Systems Operating in Low Reliability Weak Electric Grids of Developing Countries by Benson H. Mbuya, Aleksandar Dimovski, Marco Merlo, Thomas Kivevele

“…Sub-Saharan emerging countries experience electrical shortages resulting in power rationing, which ends up hampering economic activities. …”
Get full text

Analysis of the spatio-temporal impact of the built environment on shared bicycle ridership density by Na Li, Tianqun Wang

“…The results can provide more precise guidance for future rational transportation strategies or sustainable urban planning.…”
Get full text

Use of metabolites, metabolithotropic agents and nutritional supplements in sports and sports medicine: a modern view on the problem by I. F. Bielenichev, N. A. Gorchakova, E. Yu. Doroshenko, I. B. Samura, V. P. Ryzhenko, N. V. Bukhtiiarova

“…Semantic analysis data indicate that an urgent problem for sports medicine physicians and pharmacologists is the development and use of metabolites, metabolitotropic agents and nutritional supplements, as well as approaches to their rational combination to improve energy metabolism, replenish ATP reserves in the body that will help ensure the intensity muscular activity and simultaneously protect target organs.…”
Get full text

Application of information technologies for automation management of environmental activity by V. A. Rybak, A. D. Grib, Sh. Ahmad

“…For industries and technologies that do not fall into the category of rational from the point of view of environmental management, a mathematical model of their optimization has been developed with the selection of specific environmental protection measures. …”
Get full text

Structural modeling of NAD+ binding modes to PARP-1 by N. V. Ivanisenko, D. A. Zhechev, V. A. Ivanisenko

“…The structure of complex of human poly (ADP-ribose) polymerase-1 with NAD+ can be a starting point for rational design of small molecule inhibitors based on NAD+ derivatives. …”
Get full text

SPATIAL PLANNING FOR RUBBER AND COFFEE DEVELOPMENT IN KONTUM PROVINCE by Nguyễn Duy Liêm, Trần Thị Mỹ Duyên

“…Thus, it can be seen that integration of the maximum limitation method of the FAO, cost-benefit analysis and GIS could be useful in quickly and accurately evaluating land for perennial agricultural crops, providing a scientific basis for the rational spatial planning of these crops and acting as a reference to land policy makers and land use planners.…”
Get full text

Policies funnelling irregular migrants: On dispersed control in the emerging landscape of order production by Nicolay Borchgrevink Johansen

“…The claim is that funnelling policy and its rationality permeate the political and administrative handling of several marginalized groups. …”
Get full text

ISSUES OF VALUES IN ANCIENT PHILOSOPHY by Павло ОБЛАП

“…It is emphasized that, unlike the Pre-Socratics, who focused on studying the natural world and cosmological questions, the philosophers of classical Greece turned their attention to society and the state, considering that a rational (just, ideal) state is the key to personal well-being. …”
Get full text

Image double fragile watermarking algorithm based on block neighborhood by Yilong WANG, Zhenyu LI, Daofu GONG, Fenlin LIU

“…To address the security risks associated with fixed offset mapping in self-embedded watermarking technology, as well as the limited recovery rate of single watermarking methods, an image double fragile watermarking algorithm based on block neighborhood was proposed.The image was divided into non-overlapping blocks of size 4×4 and block truncation coding was used to generate the recovery watermark based on the image block.For each image block, a neighborhood of a proper size was specified and two mapping blocks were randomly selected from the regions within and outside the neighborhood.Then the recovery watermark was embedded into the two mapping blocks simultaneously.The image block neighborhood setting mechanism of the algorithm ensured that the image block maintains a certain distance from its corresponding mapping block.Additionally, the selection mechanism of mapping blocks inside and outside the image block neighborhood ensured a certain distance between the two mapping blocks, thereby guaranteeing the security of the watermark.In the case of continuous region tampering, the relationship between the tampered region and the neighborhood of the image block was analyzed theoretically.The analysis showed that a suitable image block neighborhood can improve the average recovery rate of the tampered area compared with the random mapping embedding algorithm.Besides, the distribution trend of the average recovery rate of the tampered area and the recovery rate of each image block in the tampered area were given by numerical calculation.It was found that the tampered area image block can be recovered 100%, some image blocks in the center of the tampered area can be recovered 100%, and the recovery rate of image blocks in tampered area will be reduced.The experimental results verify the rationality and effectiveness of the theoretical analysis.Moreover, when the neighborhood parameters are large, the proposed algorithm achieves a higher average recovery rate of the tampered region than the random mapping embedding algorithm in the case of continuous region tampering.…”
Get full text

ANALYSIS OF THE MAIN NOTIONS OF J.RAWLS‘ "A THEORY OF JUSTICE" by Goda Izabelė Izabelė Venslauskaitė

“…Rawls such as justice, subject of justice, ideas of cooperation and well ordered society, veil of ignorance, rationality of the original situation, principles of justice, the rule of maximum minimorum. …”
Get full text

Structural Design of Mechanical Property for Biodegradable Polymeric Stent by Yunbo Wei, Minjie Wang, Danyang Zhao, Hongxia Li, Yifei Jin

“…It is feasible to improve the axial foreshortening by using the bridges with a curved structure and locating the connecting position in the middle of the straight section of the supporting elements. The rationality of the proposed OCS and the effectiveness of the finite element method have been verified by in vitro experiments.…”
Get full text

MODUS OF SOCIAL INTEGRITY: PRACTICE OF CONSTRUCTING PRODUCTIVE CO-BEING by I. I. Brodetskaya

“…The potential of this phenomenon allows penetration of rigid rational scheme of classical political methodology, introducing the community as a spiritual practice, the experience of communitas. …”
Get full text

Diagnostic Challenges of Helicobacter pylori Infection in Ethiopia: A Community-Based Cross-Sectional Study by Esayas Kebede Gudina, Hiwot Amare, Solomon Ali, Melkamu Berhane Arefayine, Dagmawi Tewolde, Million Tesfaye Eshete, Mulusew Gerbaba Jebena, Andreas Wieser, Guenter Froeschl, Markos Tesfaye, Hailemichael Desalegn, Mulatu Gashaw

“…With these methods, it will be hard to ensure adequate diagnosis and early treatment of H. pylori infection, as well as rational antibiotic use.…”
Get full text

Examining the Methods of Guaranteeing Product Quality from the Perspective of Imami Fiqh, Iranian Law and European Union Law by Akbar Mahmoodi

“…Product quality assurance is divided into two types: guaranteeing high performance and guaranteeing quality durability, both of which are rational and expected by many buyers; But there is a possibility to differentiate between the two in the product quality guarantee contract.…”
Get full text

Research and Simulation of Cornering Characteristics on Oil and Gas Pipeline Robots by Xia Wenfeng, Yu Jiuyang, Dai Yaonan, Cheng Hang, Zhang Dean, Hu Tianhao

“…Experimental studies have found that the speed value of the experimental measurement is consistent with the simulation results, which verifies the rationality of the design.…”
Get full text