Principles of management of patient with asymptomatic elevation of serum aminotransferases by Ye. N. German, M. V. Mayevskaya, Ye. O. Lyusina, V. T. Ivashkin

“…For treatment of nonalcoholic steatohepatitis it is rational to use as drugs of choice metformin (treatment of insulin resistance) and ursodeoxycholic acid (anti-oxidative properties).…”
Get full text

Understanding the intrinsic piezoelectric anisotropy of tetragonal ABO3 perovskites through a high-throughput study by Fanhao Jia, Shaowen Xu, Shunbo Hu, Jianguo Chen, Yongchen Wang, Yuan Li, Wei Ren, Jinrong Cheng

“…Abstract A comprehensive understanding of the intrinsic piezoelectric anisotropy stemming from diverse chemical and physical factors is a key step for the rational design of highly anisotropic materials. We performed high-throughput calculations on tetragonal ABO3 perovskites to investigate the overall characteristics of their piezoelectricity and the interplay between lattice, displacement, polarization, and elasticity. …”
Get full text

Investigating the Effect of Solid Components on Yield Stress for Cemented Paste Backfill via Uniform Design by Yong Wang, Aixiang Wu, Lianfu Zhang, Fei Jin, Xiaohui Liu

“…Contribution of the four factors to yield stress in descending order is mass fraction > content of gravel > content of coarse tailings > cement versus other tailings ration. Effect of solid components on the yield stress of CPB is mainly due to the different flocculation structure inside the CPB. …”
Get full text

Effects of Flow Velocity on the Dynamics of Juvenile Fish Habitats in River Meanders of the Irtysh River by Andrey A. Chemagin, Elena I. Popova, Martin Schletterer

“…Understanding the spatial distribution of freshwater fish in heterogeneous aquatic environments is crucial for understanding riverine ecosystems and the rational use of aquatic biological resources. This study investigates the distribution patterns of juvenile fish in the lower reaches of the Irtysh River, including hydrodynamic conditions during different water level regimes. …”
Get full text

Optimization of a two-stage emergency logistics system considering public psychological risk perception under earthquake disaster by Huawei Yang, Pan Zhang, Peiwen Zhang, Chenxing Zhang, Xuxian Yan

“…The results of the study show that the two-stage optimization framework can significantly improve the rescue efficiency and rationality of resource allocation, and achieve the goal of prioritising the distribution of emergency supplies to regions with high urgency; In addition, the results of the sensitivity analysis indicate that it is crucial to determine the optimal proportion of the total amount of supplies, and the validation shows that the overall operational efficiency of PSO- SSA is higher, which provides a more reliable approach to dealing with similar emergency problems.…”
Get full text

“Allure” as an Aesthetic Element in Novel by Shirzad Tayefi, Behzad Nazemianpour

“…Since it is art, it promises us pleasure, and because it is rational, it maintains our relationship with its own internal logic and the logic of the outside world. …”
Get full text

Epistemological Review and Critique of McGregor’s Theory of Organizational Human Theory from the Perspective of the Holy Quran by Abdul Momen Hakimi, Ali Asghar Shoaei

“…The research findings show that the Qur'an does not consider reliance on reason and human findings alone to be sufficient for cognition and experience, sense and induction as preliminary steps for complete and reliable cognition based on heart faith, rational and narrative arguments. (Quran and Sunnah) which has a realistic nature with two vertical (with the Creator) and horizontal views (Jawarahi and Javanhi behaviors of the creature and the whole universe). …”
Get full text

Methodological validation study of nrCE-SDS for monoclonal antibodies by Xu Gangling, Ni Yongbo, Wu Gang, Fu Zhihao, Yu Chuanfei, Wang Lan

“…Conclusion Full validation demonstrates good accuracy, precision, linearity, range, limit of quantification, and specificity of the method, providing a reference for the scientific and rational design of corresponding methodological validations.…”
Get full text

New Benzoxazole Derivatives as Antiprotozoal Agents: In Silico Studies, Synthesis, and Biological Evaluation by Mohamed A. Abdelgawad, Mohammad M. Al-Sanea, Mohamed A. Zaki, Enas I. A. Mohamed, Shabana I. Khan, Babu L. Tekwani, Amar G Chittiboyina, Ikhlas A Khan, Tarfah Al-Warhi, Nada Aljaeed, Ohoud J. Alotaibi, Abdulsalam A. M. Alkhaldi, Heba A. H. Elshemy

“…The molecular docking study rationalizes the relative inhibitory activity of compound 5a as an antimalarial agent with the deregulation of PfPNP activity which has emerged as a major mechanism of these targets.…”
Get full text

Optimizing the thermostability of triketone dioxygenase for engineering tolerance to mesotrione herbicide in soybean and cotton by Stephen M. G. Duff, Stephen M. G. Duff, Lei Shi, Danqi Chen, Xiaoran Fu, Mingsheng Peng, Clayton T. Larue, Janice Weihe, Jessica Koczan, Brian Krebel, Qungang Qi

“…We designed an optimization scheme using a hypothesis-based rational design to improve the temperature stability of TDO. …”
Get full text

Successful Management of Teeth with Different Types of Endodontic-Periodontal Lesions by Hind Alquthami, Abdulaziz M. Almalik, Faisal F. Alzahrani, Lana Badawi

“…Understanding the disease process through cause-and-effect relationships between the pulp and supporting periodontal tissues with the aid of rational classifications leads to successful treatment outcomes. …”
Get full text

Adaptability evaluation model and experiment of full section SBM in deep strata based on AHP-fuzzy theory by Suqian Ni, Ying Xu, Peiyuan Chen, Jinjin Ge, Rongzhou Yang, Ziyi Yang, Guang Yang

“…Through the engineering case, the scientific rationality of the SBM adaptability evaluation method in the composite deep strata has been verified.…”
Get full text

Incompletely closed HIV-1CH040 envelope glycoproteins resist broadly neutralizing antibodies while mediating efficient HIV-1 entry by Durgadevi Parthasarathy, Stephanie Pickthorn, Shamim Ahmed, Dmitry Mazurov, Jeffy Jeffy, Rajni Kant Shukla, Amit Sharma, Alon Herschhorn

“…Expression of CH040 Envs was comparable to other Envs and most CH040 variants that were rationally engineered to increase bnAb resistance showed no significant decrease in their ability to mediate HIV-1 entry. …”
Get full text

Overcoming ideology-consistent biases: does it help to make things easier? by Philip U. Gustafsson, Torun Lindholm, Freja Isohanni, Ola Svenson, Sophia Appelbom

“…Thus, we demonstrate that the facilitation of complex information on a polarized topic reduces biases in favor of rational reasoning.…”
Get full text

The Spatiotemporal Pattern of the Aerosol Optical Depth (AOD) on the Canopies of Various Forest Types in the Exurban National Park: A Case in Ningbo City, Eastern China by Yufeng Chi, Shudi Zuo, Yin Ren, Kaichao Chen

“…These findings provided the guidance for the rational allocation of tree species to increase the biomass and improve the ecosystem service values of forest parks.…”
Get full text

Prediction of Water Consumption in Hospitals Based on a Modified Grey GM (0, 1∣sin) Model of Oscillation Sequence: The Example of Wuhan City by Han Zhou, Jiejun Huang, Yanbin Yuan, Biao Tang

“…Scientific forecasting of water consumption is an important approach for the rational allocation of water resources. Taking the hospitals in Wuhan City as an example and basing the analysis on the characteristics of actual water consumption, we proposed a modified grey GM (0, 1∣sin) model of oscillation sequence. …”
Get full text

Bidding Strategies for Energy Storage Participation in Electricity Market Considering Uncertainty of Wind Power and Carbon Trading by ZHANG Xianwen, YIN Gaowen, SHEN Feifan, HUANG Sheng, WEI Juan

“…The MATLAB simulation verifies the rationality and effectiveness of the proposed model in optimizing the participation of power side energy storage in multi scenario application bidding in the electricity market and improving the comprehensive operating income of the energy storage.…”
Get full text

Engineering a membrane protein chaperone to ameliorate the proteotoxicity of mutant huntingtin by Jeonghyun Oh, Christy Catherine, Eun Seon Kim, Kwang Wook Min, Hae Chan Jeong, Hyojin Kim, Mijin Kim, Seung Hae Ahn, Nataliia Lukianenko, Min Gu Jo, Hyeon Seok Bak, Sungsu Lim, Yun Kyung Kim, Ho Min Kim, Sung Bae Lee, Hyunju Cho

“…Overall, our data reveal that engineering ATP-independent membrane protein chaperones is a promising therapeutic approach for rational targeting of mHttex1 aggregation in HD.…”
Get full text

空间非对称NURBS双曲斜交单层网壳屋盖结构施工技术 by 刘克田, 刘康康, 刘芷维, 朱宝良, 陆海奇

“…以榆林职业技术学院体育馆项目竞赛馆屋盖钢结构为载体，在工期短、控造价的前提下通过比较现有空间双曲造型实现方法的优劣，创造性地提出了“标准杆件+折板弯扭节点”实现空间双曲造型的新工艺，解决了箱形截面杆件空间角度扭转时的错口问题，有效地降低了施工成本，缩短了建造周期，并形成了一套完整的空间非对称NURBS（non-uniform rational B-splines）双曲斜交单层网壳结构施工技术。…”
Get full text

Smelting separation behaviors and mechanisms of high-alumina rich-manganese ore obtained from metallic reduction and magnetic separation by Gao L.-H., Liu Z.-G., Chu M.-S.

“…In this paper the smelting separation of high-alumina rich-manganese ore prepared with selective reduction and magnetic separation was proposed to produce the high carbon ferromanganese alloy (HCFeMn). The rational smelting separation parameters for high-alumina rich-manganese ore included the FC/O of 1.1, the smelting temperature of 1550°C, the smelting time of 60 min, and the basicity of 0.7. …”
Get full text