The time has come for revising the rules of clozapine blood monitoring in Europe. A joint expert statement from the European Clozapine Task Force by Hélène Verdoux, Robert A. Bittner, Alkomiet Hasan, Mishal Qubad, Elias Wagner, Alexis Lepetit, Manuel Arrojo-Romero, Christian Bachmann, Marieke Beex-Oosterhuis, Jan Bogers, Andreja Celofiga, Dan Cohen, Domenico de Berardis, Marc de Hert, Carlos de Las Cuevas, Bjørn H. Ebdrup, Konstantinos N. Fountoulakis, Daniel Guinart, Dolores Keating, Miloslav Kopeček, John Lally, Judit Lazáry, Jurjen J. Luykx, Olalla Maronas Amigo, Espen Molden, Jimmi Nielsen, Brian O’Donoghue, Pierre Oswald, Flavian S. Radulescu, Christopher Rohde, Marina Sagud, Emilio J. Sanz, Ivona Šimunović Filipčić, Iris E. Sommer, Heidi Taipale, Jari Tiihonen, Heli Tuppurainen, Selene Veerman, Alina Wilkowska, Edoardo Spina, Peter Schulte

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Preclinical use of a clinically-relevant scAAV9/SUMF1 vector for the treatment of multiple sulfatase deficiency by Maximiliano Presa, Rachel M. Bailey, Somdatta Ray, Lauren Bailey, Saurabh Tata, Tara Murphy, Pierre-Alexandre Piec, Harold Combs, Steven J. Gray, Cathleen Lutz

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Characterization of the bispecific VHH antibody tarperprumig (ALXN1820) specific for properdin and designed for low-volume administration by Paul Tamburini, Dennis Vestergaard Pedersen, Denise Devore, Josh Cone, Rekha Patel, Todd Hunter, Fang Sun, Gregers Rom Andersen, Jeffrey Hunter

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Phenylbutyric Acid Modulates Apoptosis and ER Stress‐Related Gene Expression in Glycogen Storage Disease Type Ib In Vitro Model by Marina Parezanovic, Nina Stevanovic, Marina Andjelkovic, Milena Ugrin, Sonja Pavlovic, Maja Stojiljkovic, Anita Skakic

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Generation of an induced pluripotent stem cell line (UCLi026-A) from a patient with ADCY5-related disease carrying the heterozygous variant c.1253G > A; (p. Arg418Gln) by Sharmin Alhaque, Dimitri Budinger, Barbara Garavaglia, Giovanna Zorzi, Serena Barral, Manju A. Kurian

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Genome-wide association studies with prolapsed gland of the third eyelid in dogs by Yu Zeng, Yu Zeng, Yu Zeng, Cundong Feng, Zheli Jiang, Zheli Jiang, Zheli Jiang, Weian Du, Shan He, Shan He, Shan He, Xingnuan Li, Xingnuan Li, Xingnuan Li, Yi Fan, Yi Fan, Yi Fan, Xiao Ouyang, Xiao Ouyang, Xiao Ouyang, Bixin Huang, Bixin Huang, Bixin Huang, Yan Su, Yan Su, Yan Su, Siyu Wang, Siyu Wang, Siyu Wang, Rongxing Wei, Zonghao Dai, Peng Jin, Jianyun Liu, Jianyun Liu, Jianyun Liu, Qianyong Yang, Qianyong Yang, Qianyong Yang

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Poor Outcomes in Hepatic Amyloidosis: A Report of 2 Cases by Brandon Yim, Elizabeth Kertowidjojo, Yue Zhang, Pruthvi Patel

“…Hepatic amyloidosis is a rare disease entity that results from insoluble amyloid protein deposition in the liver. …”
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Functional and structural characterization of mouse Factor H-related B protein unveils a novel dimerization domain shared by FHR-B and FH by Adrián Martín-Ambrosio Doménech, Silvia González Sanz, Bárbara Márquez Tirado, Lucia Juana-López, Elena Goicoechea de Jorge, Santiago Rodríguez de Córdoba, Héctor Martín Merinero

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Chronic Mastocytosis. Case Report and Literature Review by Iraima Mayón Moya, Danibys Garcell Peña, José Manuel Peraza Ramos

“…The case is presented because mastocytosis is considered a rare disease, the prevalence and incidence of these cases is very low.…”
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Idiopathic Organ Transplant Chorioretinopathy after Liver Transplantation by Maria Fernanda Abalem, Pedro Carlos Carricondo, Sergio Luis Gianotti Pimentel, Walter Yukihiko Takahashi

“…Idiopathic organ transplant chorioretinopathy is a rare disease associated with kidney and heart transplantation. …”
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Signet Ring Cell Carcinoma of the Lung: A Diagnostic Pitfall in Pregnancy by Sabine Danzinger, Wolfgang J. Köstler, Martin Funovics, Merima Herac, Leonhard Müllauer, Helmut Prosch, Heinz Kölbl

“…Lung cancer during pregnancy represents a rare disease. In this case report, we present a patient at advanced and metastasized stage of signet ring cell carcinoma who presented in the 22nd week of gestation.…”
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Lymphomatoid granulomatosis with rare manifestations. Case report by Pedro Rosales Torres, Pedro León Acosta

“…Introduction: lymphomatoid granulomatosis is a very rare disease; This is the first case reported in the hospital. …”
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Yellow Nails, Lymphedema and Chronic Cough: Yellow Nail Syndrome in an Eight-Year-Old Girl by Ishita Siddiq, Daniel Hughes

“…Yellow nail syndrome is a rare disease and reported mainly in adults. A case of yellow nail syndrome involving an eight-year-old girl with associated discoloured yellowish nails on the fingers and toes, lymphedema and chronic cough, and sputum production is reported.…”
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Epidermoid Cyst of Orbit in a Newborn by Handan Canan, Rana Altan-Yaycioglu, Nebil Bal, Birgin Törer, Bilin Çetinkaya-Çakmak, Hande Gülcan

“…Clinicopathological features of this rare disease are discussed.…”
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Multiple-System Atrophy with Cerebellar Predominance Presenting as Respiratory Insufficiency and Vocal Cords Paralysis by Ramon Andrade Bezerra de Mello, Diana Ferreira, José Manuel Dias da Costa, Maria José Rosas, João Manuel Quinaz

“…It is considered a rare disease, but many patients are misdiagnosed as suffering from idiopathic Parkinson's disease. …”
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Invasive Liver Abscess Syndrome in the Immunocompromised: A Case Report by Amey Joshi, Eki Wari, Harith Ghnaima, Georgette Nader, Surya Chennupati, Nagham Jafar

“…Early recognition in non‐endemic regions is crucial for prompt antibiotic therapy and source control, highlighting the need for increased suspicion and aggressive management of this rare disease to improve patient outcomes.…”
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Idiopathic Myointimal Hyperplasia of Mesenteric Veins of the Ileum and Colon in a Patient with Crohn’s Disease: A Case Report and Brief Review of the Literature by Sharon J. Song, Stuti G. Shroff

“…Idiopathic myointimal hyperplasia of the mesenteric veins (IMHMV) is a rare disease characterized by intimal smooth muscle proliferation, leading to the thickening of small to medium-sized mesenteric veins. …”
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Diagnosis of Primary Langerhans Cell Histiocytosis of the Vulva in a Postmenopausal Woman by Sefa Kurt, Mehmet Tunc Canda, Aycan Kopuz, Dudu Solakoglu Kahraman, Abdullah Tasyurt

“…Langerhans cell histiocytosis (LCH) is a very rare disease of female genital tract, most commonly seen in vulva and unusual in postmenopausal period. …”
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Optical Coherence Tomography Angiography of Nonarteritic Cilioretinal Artery Occlusion Alone by Toyo Ikebukuro, Tsutomu Igarashi, Shuhei Kameya, Takeshi Arima, Tomoyuki Kunishige, Hiroshi Takahashi

“…Cilioretinal artery occlusion (CLRAO) is a rare disease. Here, we report the case of a 70-year-old man with nonarteritic cilioretinal artery occlusion alone. …”
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Erosive Arthritis, Fibromatosis, and Keloids: A Rare Dermatoarthropathy by Fawad Aslam, Jonathan A. Flug, Yousif Yonan, Shelley S. Noland

“…Polyfibromatosis is a rare disease characterized by fibrosis manifesting in different locations. …”
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