The effectiveness of the use of filter on the tilapia growth performance, number of Nitrosomonas sp., and water quality in aquaponics systems by Yuli Andriani, , Zahidah, Yayat Dhahiyat, Ujang Subhan, Irfan Zidni, Rusky Intan Pratama, Nadia Purnamasari Gumay

“…The method used in this study was completely randomized design, consisting of five treatments and each was repeated three times. …”
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PREVALENCE OF WORK-RELATED MUSCULOSKELETAL DISORDERS AMONG IRANIAN ORTHOTISTS AND PROSTHETISTS: A STUDY ON WORK-RELATED QUALITY OF LIFE by Sarina Azizi, Vahideh Moradi, Behnam Hajiaghaei, Taher Babaee

“…A group of 263 orthotists and prosthetists were invited to complete the questionnaires using a simple random sampling method. The data from 188 respondents were analyzed. …”
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Effect of psychological intervention of sandplay therapy on children without accompanying in Neurosurgery Department under the normalization of epidemic prevention and control (常态化... by XIN Jie (辛杰), ZHANG Hongyang (张宏扬), ZHU Ruifang (朱瑞芳)

“…Methods Totally 170 children who were admitted to the hospital for surgery from February 2021 to May 2022 were enrolled. Random sampling methods were used to divide the children into the control group (n=85) and the intervention group (n=85) according to whether they were treated with sandplay therapy. …”
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Effects of different rapeseed varieties on egg production performance, egg quality, hormone levels, follicle development, and thyroid function in hens by Liping Zhu, Jianping Wang, Xuemei Ding, Shiping Bai, Qiufeng Zeng, Yue Xuan, Keying Zhang

“…A total of 600 laying hens at 33 wk of age were randomly divided into 5 treatments containing a control diet and 4 diets with 11.5% rapeseed. …”
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The Combined Effect of Garlic (Allium sativum) and Turmeric (Curcuma longa) Extracts to Reduce the Adverse Effects of Aflatoxin B1 in Rats by Hadi Sarir, Saeedeh Zakerian, masood didarkhah

“…The aim of this research is to investigate the effect of the combination of garlic and turmeric extract on the amount of plasma aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, the amount of triiodothyronine, thyroxine, total antioxidant capacity, and malondialdehyde in rats intoxicated with aflatoxin B1.Materials and Methods: In this research, 64 male Wistar rats with an average body weight of 250-300 g were used to evaluate the synergistic effect of garlic and turmeric extract against the damage caused by aflatoxin B1 in the form of a completely randomized design as a factorial experiment (2×2×2). …”
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Observation on the curative effect of umbilicus application therapy combined with Cucurbit moxibustion in the treatment of spleen deficiency syndrome of type 2 diabetes mellitus (敷... by GAO Junluan (高俊娈), XUE li (薛丽), ZHANG Gengliang (张庚良), HAO Min (郝民), MAO Hui (毛慧), SHEN Yanru (沈彦如)

“…Methods Using convenience sampling method, 60 patients with type 2 diabetes admitted to our hospital from March 2020 to December 2020 were selected as the research objects, and randomly divided into two groups, 30 people in each group. …”
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Clinical effect of auricular point pressing with beans combined with acupoint massage in the treatment of post-stroke constipation with Qi deficiency syndrome (耳穴压豆联合穴位按摩治疗中风后气虚便秘的... by LI Chenchen (李陈晨), YANG Yu (杨宇), FAN Yan (范艳), JIA Tieying (贾铁英), HU Shirong (胡世荣)

“…Methods Totally 120 patients with post-stroke constipation of Qi deficiency syndrome were randomly divided into control group and study group, with 60 cases in each group. …”
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Optimization of salinity range for rearing glass eel Anguilla bicolor bicolor by Ade Yulita Hesti Lukas, Daniel Djokosetiyanto, Tatag Budiardi, Agus Oman Sudrajat, Ridwan Affandi

“…It used a completely randomized design (CRD) with four salinity treatments and three replications, namely (A) 0 g/L, (B) 10 g/L, (C) 20 g/L, and (D) 30 g/L. …”
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A prospective cohort study on the impact of healthy lifestyles on all-cause and cardiovascular disease mortality among adult residents in Guizhou province by Jie ZHOU, Ling LI, Ji ZHANG, Lisha YU, Yujin REN, Wei JI, Yingjiao MU, Tao LIU

“…MethodsA prospective cohort study was conducted using a multi-stage cluster random sampling method to recruit 9 280 permanent residents aged ≥ 18 years in Guizhou province from November 2010 to December 2012 for a baseline survey. …”
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Influence of ethnicity on cyclin-dependent kinase inhibitor efficacy and toxicity: A systematic review and meta-analysis by Roberto Buonaiuto, Aldo Caltavituro, Margherita Tafuro, Alessandra Longobardi, Giuliana Pavone, Pierluigi De Santis, Roberta Caputo, Carmine De Angelis, Lucia Del Mastro, Fabio Puglisi, Mario Giuliano, Grazia Arpino, Martina Pagliuca, Michelino De Laurentiis

“…Methods: We conducted a meta-analysis including the most recent randomized trial data systematically searched from PubMed, Embase, Web of Science, Cochrane CENTRAL (from inception to May 31st, 2024) or presented in abstracts or oral presentations at the ESMO, ASCO, and SABCS international congresses. …”
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Second-line treatment patterns and outcomes in advanced HCC after progression on atezolizumab/bevacizumab by Meng Wu, Claudia A.M. Fulgenzi, Antonio D’Alessio, Alessio Cortellini, Ciro Celsa, Giulia F. Manfredi, Bernardo Stefanini, Y. Linda Wu, Yi-Hsiang Huang, Anwaar Saeed, Angelo Pirozzi, Tiziana Pressiani, Lorenza Rimassa, Martin Schoenlein, Kornelius Schulze, Johann von Felden, Yehia Mohamed, Ahmed O. Kaseb, Arndt Vogel, Natascha Roehlen, Marianna Silletta, Naoshi Nishida, Masatoshi Kudo, Caterina Vivaldi, Lorenz Balcar, Bernhard Scheiner, Matthias Pinter, Amit G. Singal, Joshua Glover, Susanna Ulahannan, Fredrich Foerster, Arndt Weinmann, Peter R. Galle, Neehar D. Parikh, Wei-Fan Hsu, Alessandro Parisi, Hong Jae Chon, David J. Pinato, Celina Ang

“…These results can help inform clinicians of possible treatment options for patients who progress after frontline atezolizumab plus bevacizumab while we await maturing data from randomized-controlled trials.…”
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Protective mechanism of safflower yellow injection on myocardial ischemia-reperfusion injury in rats by activating NLRP3 inflammasome by Lingmei Li, Ce Cao, Hao Guo, Li Lin, Lei Li, Yehao Zhang, Gaojie Xin, Zixin Liu, Shujuan Xu, Xiao Han, Qiong Zhang, Jianhua Fu

“…Methods The I/R model was prepared by ligating the left anterior descending coronary artery for 45 min and then releasing the blood flow for 150 min. 96 male Wistar rats were randomly divided into sham group, I/R group, Hebeishuang group (HBS), SYI high-dose group (I/R + SYI-H), SYI medium-dose group (I/R + SYI-M) and SYI low-dose group (I/R + SYI-L). …”
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AI-based tumor-infiltrating lymphocyte scoring system for assessing HCC prognosis in patients undergoing liver resection by Zhiyang Chen, Tingting Xie, Shuting Chen, Zhenhui Li, Su Yao, Xuanjun Lu, Wenfeng He, Chao Tang, Dacheng Yang, Shaohua Li, Feng Shi, Huan Lin, Zipei Li, Anant Madabhushi, Xiangtian Zhao, Zaiyi Liu, Cheng Lu

“…We trained a deep neural network and a random forest model to segment tumor regions and locate CD8+ TILs in H&E and CD8-stained whole-slide images. …”
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Extended HPV genotyping by the BD Onclarity assay: concordance with screening HPV-DNA assays, triage biomarkers, and histopathology in women from the NTCC2 study by Laura De Marco, Simonetta Bisanzi, Guglielmo Ronco, Pamela Mancuso, Francesca Carozzi, Elena Allia, Raffaella Rizzolo, Daniela Gustinucci, Helena Frayle, Jessica Viti, Anna Iossa, Elena Cesarini, Simonetta Bulletti, Basilio Passamonti, Silvia Gori, Laura Toniolo, Francesco Venturelli, Annarosa Del Mistro, Paolo Giorgi Rossi, Maria Benevolo

“…Nevertheless, the agreement is substantial for women with high-grade cytology, histologically confirmed CIN3, and p16/ki67 or mRNA positivity at triage, thus confirming a good clinical performance of all the tests used.The NTCC2 trial is registered as Clinicaltrials.gov identifier NCT01837693.IMPORTANCELarge randomized clinical trials have demonstrated that human papillomavirus (HPV) testing for high-risk types is more effective than cytology in detecting pre-cancerous lesions and preventing cervical cancer. …”
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Integrated microbiome, transcriptome and metabolome insight into the alleviating mechanisms of sheep milk in a DSS-induced colitis mouse model by Wenna Yao, Ruilin Du, Shuo Yan, Teligun Bao, Huimin Zhang, Fang Yang, Yue Xue, Yulong Zhao, Siqin Bao, Xihe Li, Yongli Song

“…In this study, 30 mice were randomly divided into 3 groups. Mice had free access to sheep milk for 14 days, and free access to 2.5 % DSS started on the 7th day of SM administration and sustained for 7 days. …”
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Application of Shenling lotion in nursing of perineal injury after vaginal delivery (参苓洗液在经阴道分娩产妇产后会阴损伤护理中的应用效果研究) by TANG Yang (唐杨), PENG Hong (彭鸿), WU Qiuxiang (吴秋香), WANG Yan (王燕), WANG Mingyang (王明洋), CHEN Lingfang (陈陵芳)

“…Methods A total of 200 puerperal women after vaginal delivery were randomly divided into the control group and observation group, with 100 cases in each group. …”
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Practice of continuing care with Traditional Chinese Medicine nursing for patients after surgical treatment of mixed hemorrhoids in the specialized outpatient clinic (基于专病门诊的混合痔术后患... by Qin Shasha (秦沙沙), E Haiyan (鄂海燕), WEI Yongchun (魏永春), PENG Yujie (彭雨洁), TANG Ling (唐玲), LI Ye (李野), WANG Yali (王亚丽), DONG Yuxia (董玉霞)

“…Methods Totally 80 patients undergoing surgical treatment of mixed hemorrhoids of Damp-Heat type were randomly divided into the observation group and the control group, with 40 cases in each group. …”
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Application of mind-mapping combined with scenario simulation method in clinical teaching and training of cardiopulmonary resuscitation skills of nursing students (思维导图联合情景模拟的教学方式在... by ZHAO Lina (赵丽娜), LIU Ai (刘爱), WANG Honghong (王虹虹), WANG Xiaojie (王小杰), TONG Lu (佟璐), ZHANG Ji (张继), ZUO Lin (左琳), MING Yue (明月), CHEN Xinxin (陈鑫鑫), WANG Yuanyuan (王媛媛)

“…Methods A total of 24 nursing students who participated in the internship in the Emergency Medicine Department were randomly divided into the control group and study group, with 12 students in each group. …”
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EDENT1FI Master Protocol for screening of presymptomatic early-stage type 1 diabetes in children and adolescents by Melanie Gündert, Anette-Gabriele Ziegler, Peter Achenbach, Olga Kordonouri, Agnieszka Szypowska, Ezio Bonifacio, Parth Narendran, Christiane Winkler, R Ribeiro, Sandra Hummel, Przemysława Jarosz-Chobot, Emanuele Bosi, R Lahesmaa, K Casteels, M Peakman, P Jarosz-Chobot, O Kordonouri, Chantal Mathieu, Vito Lampasona, J F Raposo, H Hyöty, F Pociot, João Filipe Raposo, R Berner, R Bergholdt, E Bonifacio, Flemming Pociot, B Petersen, J Van Rampelbergh, L Overbergh, B Van der Schueren, V Lampasona, C Winkler, R Coelho, O Cohen, C Mathieu, E Bosi, Stefanie Arnolds, Lut Overbergh, Zdenek Sumnik, A Koralova, G Sebastiani, Luisa Hoffmann, Mirjam Kohls, Regine Bergholdt, Bianca K Hoefelschweiger, Jurgen Vercauteren, P Gillard, J Vercauteren, A G Ziegler, P Achenbach, F Haupt, S Hummel, T Pieber, J Mader, S Moitzi, S Del Prato, B Torbeyns, Z Sumnik, O Cinek, V Neuman, B Berka, J Antvorskov, J H Klaebel, J E Laiho, F Reschke, T von dem Berge, A Hommel, A Loff, G Gemulla, N Zubizarreta, L Piemonti, F Dotta, A Szypowska, K Karczewski, E Niemoeller, M Baccara-Dinet, K Fogh, M I Buompensiere, C Hurtado del Pozo, E Latres, G Agiostratidou

“…Children and adolescents with confirmed two or more autoantibodies are invited to metabolic staging (oral glucose tolerance test, haemoglobin A1c (HbA1c), random glucose, optionally continuous glucose monitoring); an educational programme and recommendations for monitoring are provided. …”
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Spatial heterogeneity determines the gastrointestinal microbiome signatures and ecological processes that govern bacterial community assembly in sheep by Yukun Zhang, Jiangbo Cheng, Changchun Lin, Fadi Li, Xiaoxue Zhang, Chong Li, Deyin Zhang, Xiaobin Yang, Dan Xu, Yuan Zhao, Liming Zhao, Xiaolong Li, Huibin Tian, Xiuxiu Weng, Weimin Wang

“…The assembly processes in the four-chambered stomach and small intestine resembled random selection, where bacterial positioning depended on luck and chance, while in the large intestine, it appeared more deterministic, with specific bacteria likely selected based on their unique skills and environmental requirements. …”
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