Recent advances in systemic therapy for advanced biliary tract cancer: A systematic review and meta-analysis using reconstructed RCT survival data by Zhihao Li, Daniel Aliseda, Owen Jones, Luckshi Rajendran, Christian Magyar, Robert Grant, Grainne M. O’Kane, Anna Saborowski, Gonzalo Sapisochin, Arndt Vogel

“…Methods: Our systematic review included studies from five databases focusing on English-language articles published between January 2010 and June 2024. We included randomized clinical trials (RCTs) that featured GemCis in a treatment arm for treatment-naive adults with advanced BTCs. …”
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Association of rs3755319 and rs4148325 of the <i>UGT1A1</i> gene, rs2328136 of the <i>NUP153-AS</i> gene, and rs16928809 of the <i>SLC22A18</i> gene with benign unconjugated hyperb... by Anastasiya A. Ivanova, Natalia E. Apartseva, Anastasiia P. Kashirina, Elena G. Nemcova, Julija V. Ivanova, Margarita V. Kruchinina, Svetlana A. Kurilovich, Vladimir N. Maksimov

“…Methods: This case-control study included a group of individuals with benign unconjugated hyperbilirubinemia (n = 414, mean age 36.7 ± 15.9 years, 49.8% men) and a control group (n = 381, mean age 39.1 ± 15.9 years, 52.5% men). The sample was randomly selected from the participants of the MONICA project, screening of young people aged 25–44 years and a cross-sectional study of schoolchildren in Novosibirsk. …”
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Evaluation of Yield and Yield Components of Different Ecotypes of Black Cumin (Nigella sativa L.) to Planting Date in Gorgan by Mohammad Sadeq Ashrafi, Farshid Ghaderi-Far, Elias Soltani, Ebrahim Zeinali, Asieh Siahmarguee

“…The experiment was carried out in the form of split plots based on completely randomized block statistical design with three replication, in which four planting dates were 18th December, 17th January, 16th February and 18th March as the main plot and thirteen ecotypes (Such as Tafaresh, Gardmiran, Razan, Hamedan, Arak, Esfahan, Semirom, Eqlid, Ashkazar, Zabol, Bajestan, Sarayan and Khaf) with 3 replication were considered as sub-plot. …”
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A Study on the Yield Stability of Oilseed Sunflower Genotypes under Drought Stress by Nasrin Akbari, Reza Darvishzadeh

“…In this regard, the analysis of variance (ANOVA) was done with a mixed linear model, considering the environment and genotype as fixed effects and the year and replication as random effects. SAS software version 4.9 was used for ANOVA, and the STABILITYSOFT program under the R environment was used for stability analysis. …”
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Comparison of Hyperbaric 0.5% Levobupivacaine and Hyperbaric 0.75% Ropivacaine for Intrathecal Use in Infraumbilical Surgeries: A Randomised Clinical Study by Tejash H Sharma, Jagrati Jain, Priya Kishnani, Richa Tailor, Sara Mary Thomas

“…Patients with American Society of Anaesthesiologists (ASA) I/II status were randomly allocated into two equal groups of 20 each. …”
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Jiangu Granules Regulates Endoplasmic Reticulum Stress-Induced Apoptosis in UMR-106 Cells by Modulating the PERK/eIF2α/ATF4/CHOP Pathway by CHEN Sainan, ZHOU Fen, HUANG Yunmei, LIN Yanping

“…UMR-106 cells exhibiting favorable growth status were randomly allocated into four groups: negative control group (NC group), model group (H₂O₂ group), Jiangu Granules group (H₂O₂+JG group), and positive control group (H₂O₂+GSK2606414 group). …”
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The Effect of Feeding Different Levels of Mineral Biochar on Performance, Blood Parameters, Production and Milk Composition of Holstein Dairy Cows by Ali Khatibi Bardsiri, Reza Valizadeh, Seyed Hadi Ebrahimi, Pirouz Shakeri, Abbas Ali Naserian

“…The experiment was conducted in the form of a completely random design with three treatments, so that there were eight cows in each group. …”
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Assessing Facial Thermal Nociceptive Response in Female Dogs After Elective Ovariohysterectomy Anesthetized with Isoflurane and Treated with Cannabidiol and Meloxicam Analgesia by Alejandro Casas-Alvarado, Patricia Mora-Medina, Ismael Hernández-Avalos, Julio Martínez-Burnes, Agatha Miranda-Cortes, Adriana Domínguez-Oliva, Daniel Mota-Rojas

“…Sixty-four female dogs of different breeds were randomly distributed into four study groups according to the treatment received. …”
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Intimate partner violence among women of reproductive age during the COVID-19 pandemic in Ethiopia: a systematic review and meta-analysis by Gizachew Yilak, Alemayehu Sayih Belay, Aychew Kassie, Befkad Derese Tilahun, Ambaw Abebaw Emrie, Mulat Ayele, Eyob Shitie Lake, Legese Fekede Abza

“…The heterogeneity between studies was assessed using I2 test statistics and the random-effects meta-analysis was done using the restricted maximum likelihood method. …”
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Effects of early pulmonary rehabilitation exercise on the lung function and indicators of arterial blood gas analysis in patients with severe chronic obstructive pulmonary disease... by XU Nannan (徐楠楠), HONG Hanhan (洪涵涵)

“…Methods Seventy patients with severe COPD undergoing pulmonary rehabilitation were selected as the study objectis, and were randomly divided into the observation group and the control group, with 35 patients in each group. …”
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Feasibility study of ‘Triple-Low’ technique for coronary artery computed tomography angiography (CCTA) by Shaochuan Wang, Zhengwen Sun, Yihong Zeng, Xinyu Xu, Yan Wang, Xueqin Liu, Yonggui Yang

“…We prospectively collected data from 90 patients who underwent CCTA at our hospital between 2021 and 2024. The patients were randomly assigned to either the experimental group (n = 45) or the control group (n = 45). …”
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Impact of antiviral prophylaxis on EBV viremia and posttransplant lymphoproliferative disorders in solid organ transplant recipients: a systematic review and meta-analysis by Marjan Moghadamnia, Khadijeh Delroba, Shima Heidari, Zahra Rezaie, Simin Dashti-Khavidaki

“…Method A comprehensive search was conducted up to December 31, 2023, in databases including PubMed, Embase, and the Cochrane Library for retrospective and prospective studies comparing antiviral prophylaxis effects on EVB viremia and PTLD incidence in SOT recipients. Fixed or random effect models were applied based on the heterogeneity assessed via the I2 statistic, using Stata 16.0 software for data analysis. …”
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Investigating the Effect of Different Levels of Butyric Acid Glycerides and Clove Oil on Growth Performance, Blood Parameters and Tibia Bone Characteristics of Broiler Chickens by Seyyedeh azam khatami, Mir Daryoush Shakouri, Nemat Hedayat Evrigh

“…Material and Methods: A total of 300 male and female broilers (Ross 308) with a completely randomized design with a 2 × 3 factorial arrangement, two levels of butyric acid glycerides (0 and 0.2 %) and three levels of clove oil (0, 500 and 1000 mg/kg) were used. …”
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Beneficial and harmful effects of duloxetine versus placebo, ‘active placebo’ or no intervention for adults with major depressive disorder: a systematic review with meta-analysis a... by Christian Gluud, Marija Barbateskovic, Joanna Moncrieff, Faiza Siddiqui, Janus C Jakobsen, Mathias Maagaard, Sophie Juul, Johanne Juul Petersen, Caroline Barkholt Kamp, Mark Abie Horowitz, Kiran Kumar Katakam

“…Intervention effects were assessed by both random-effects and fixed-effect model meta-analyses, risk of bias assessments were performed by two independent review authors using Cochrane’s risk of bias tool V.2 and the certainty of evidence was assessed using Grading of Recommendations Assessment, Development and Evaluation.Results We included 28 trials randomising a total of 7872 participants. …”
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Early and high-volume administration of sodium bicarbonate in sepsis-associated acute kidney injury in patients with malignancies, during continuous renal replacement therapy by Lamei Ouyang, Yin Pan, Ya-Fei Wu, Qiang Tang, Dao-Feng Wang, Ning Lou

“…Furthermore, the duration of mechanical ventilation (7.0 ± 3.33 days) was lower in the early high-volume group compared to the other groups (8.0 ± 1.12 days,10.0 ± 1.11 days, and 8.0 ± 2.65 days; χ2 =8.064, p = 0.045), as was the length of ICU stay (7.0 ± 0.89 days) compared to the other groups (13.0 ± 3.35 days, 10.0 ± 1.49 days, and10.0 ± 3.70 days; χ2 = 9.184, p = 0.027).Conclusion Early and high-volume administration of sodium bicarbonate during CRRT may reduce 28-day mortality and improve shock reversal rates in patients with sepsis-associated acute kidney injury complicated by malignancy. Prospective randomized controlled large sample studies are needed to confirm this.…”
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Effect of auricular holographic copper-plate scrapping combined with auricular acupoint pressing therapy in the treatment of nonspecific low back pain of cold-dampness obstruction... by REN Fang (任芳), ZHOU Haiying (周海英), BAI Yang (白洋), LI Lijuan (李利娟)

“…Methods Totally 90 patients with nonspecific low back pain of cold-dampness obstruction type were randomly divided into the control group and observation group, with 45 cases in each group. …”
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Effect of Exercise Preconditioning on Myocardia Ischemia-Reperfusion Injury in Aged Rats by Hongyu LI, Xia YIN, Shiqiang ZHANG, Luwen ZHU, Qiang TANG

“…Objective:To observe the effects of exercise preconditioning on cardiac function, myocardial infarct area, cardiomyocyte ultrastructure and antioxidant capacity of aged rats after isolated myocardial ischemia-reperfusion injury.Methods:A total of 60 SPF male SD aged rats were randomly divided into the control group (Con group), the ischemia-reperfusion model group (IR group), the exercise preconditioning+ischemia-reperfusion group (EP+IR group), the ischemic preconditioning group (IPC group) and the exercise preconditioning+ischemic preconditioning group (EP+IPC group), with 12 rats in each group. …”
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Risk Factors of Portal Vein Thrombosis in Patients with Different Child-Pugh Classes Liver Cirrhosis by M. Yu. Nadinskaia, Kh. B. Kodzoeva, K. A. Gulyaeva, M.-D. E. Khen, D. I. Koroleva, M. A. Privalov, A. Kh. Tekaeva, V. R. Fedorov, S. G. Prokofev

“…From the database of cirrhotic patients without PVT 60 Controls for class A and 205 for B/C were selected using sratified randomization by sex, age and etiology of cirrhosis. …”
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The synergetic effect of selenium or zinc oxide nanoparticles with chromium on mitigating thermal stress for sustainable production and improving antioxidant capacity and inflammat... by I. T. El-Ratel, K. H. El-Kholy, S. M. Elgmmal, S. F. Fouda, A.-K. E. Abdel-Khalek, M. A. Hassan, M. M. Azzam, M. Alagawany, A. Lestingi

“…A total of 100 newly weaned APRI rabbits were randomly divided into five homogeneous groups. A basal diet containing no feed additives (0 g per kg diet) was given to the first group, and the second, third, fourth, and fifth groups were given a diet supplemented with 0.3 mg SeNPs, 20 mg ZnONPs, 0.3 mg SeNPs and 1.5 mg Cr, and 20 mg ZnONPs and 1.5 mg Cr per kg diet, respectively. …”
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Effect of Traditional Chinese Medicine Baduanjin exercise combined with remote ischemic conditioning on mild cognitive impairment after stroke (中医传统功法八段锦联合远隔缺血适应治疗脑卒中后轻度认知障碍的效果研究)... by XUE CHAO (薛超), LI Juan (李娟), FANG Qian (方茜), CHEN Lihua (陈丽华), HAO Mingqing (郝明青), CHEN Zuoxiu (陈作秀)

“…Methods Seventy patients with mild cognitive impairment after stroke were recruited as study subjects and randomly divided into control group(n=35) and intervention group(n=35). …”
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