The impact of glucagon-like peptide-1 (GLP-1) agonists in the treatment of eating disorders: a systematic review and meta-analysis by Hanieh Radkhah, Shiva Rahimipour Anaraki, Peyvand Parhizkar Roudsari, Razman Arabzadeh Bahri, Diar Zooravar, Sara Asgarian, Reza Hosseini Dolama, Ali Alirezaei, Razieh Khalooeifard

“…Level of evidence Level I, randomized controlled trials.…”
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Novel combination therapy for platinum-eligible patients with locally advanced or metastatic urothelial carcinoma: a systematic review and network meta-analysis by Takafumi Yanagisawa, Keiichiro Mori, Akihiro Matsukawa, Tatsushi Kawada, Satoshi Katayama, Ekaterina Laukhtina, Pawel Rajwa, Fahad Quhal, Benjamin Pradere, Wataru Fukuokaya, Kosuke Iwatani, Renate Pichler, Jeremy Yuen-Chun Teoh, Marco Moschini, Wojciech Krajewski, Jun Miki, Shahrokh F. Shariat, Takahiro Kimura, European Association of Urology–Young Academic Urologists Urothelial Carcinoma Working Group (EAU-YAU)

“…Abstract Recent phase 3 randomized controlled trials (RCTs) demonstrate the promising impact of immune checkpoint inhibitor (ICI)-based combination therapies on locally advanced or metastatic urothelial carcinoma (UC). …”
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Tumor Size Is a Critical Factor in Adjuvant Chemotherapy for T3-4aN0M0 Gastric Cancer Patients after D2 Gastrectomy by Shi Chen, Li-Ying Ou-Yang, Run-Cong Nie, Yuan-Fang Li, Jun Xiang, Zhi-Wei Zhou, Ying-Bo Chen, Jun-Sheng Peng

“…Additional randomized controlled trials are required before this conclusion can be considered definitive.…”
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Incidence of hyperkalemia RAASi and SGLT-2i treatment in individuals with diabetic kidney disease: a systematic review and network meta-analysis by Yahui Yuan, Yahui Yuan, Yahui Yuan, Chun Chen, Yuping Lin, Yehao Luo, Yehao Luo, Yehao Luo, Zhaojun Yang, Zhaojun Yang, Zhaojun Yang, Jingyi Guo, Jingyi Guo, Jingyi Guo, Qiaoyun Liu, Qiaoyun Liu, Qiaoyun Liu, Lu Sun, Guanjie Fan, Guanjie Fan, Guanjie Fan

“…BackgroundThis study aims to evaluate the incidence of hyperkalemia and serum potassium levels associated with the use of sodium-glucose cotransporter-2 inhibitors (SGLT-2i), renin‐angiotensin‐aldosterone system inhibitors (RAASi) and concurrent use of these medications in individuals with diabetic kidney disease (DKD).MethodsA comprehensive systematic search was performed in EMBASE, the Cochrane Central Register of Controlled Trials (CENTRAL), Web of Science, Scopus, and PubMed database, covering studies up to March 2024. Relevant randomized controlled trials (RCT) included adults with DKD who were treated with SGLT-2i and RAASi or their combination, with a minimum follow-up duration of 12 weeks. …”
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Safety and Effectiveness of BPaL-Based Regimens to Treat Multidrug-Resistant TB: First Experience of an Italian Tuberculosis Referral Hospital by Gina Gualano, Maria Musso, Paola Mencarini, Silvia Mosti, Carlotta Cerva, Pietro Vittozzi, Antonio Mazzarelli, Angela Cannas, Assunta Navarra, Stefania Ianniello, Paolo Faccendini, Fabrizio Palmieri

“…Based on the evidence generated by the TB-PRACTECAL and ZeNix randomized controlled trials, BPaL/BPaLM regimens are recommended over the currently recommended longer regimens in patients with MDR-TB or monoresistance to rifampin (RR). …”
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Comparative Efficacy and Safety of Targeted Therapies for Chronic Thromboembolic Pulmonary Hypertension: A Systematic Review and Network Meta-Analysis by Yusi Chen, Fang Li, Jun Luo, Jingyuan Chen, Peng Luo, Jiang Li

“…A large number of randomized controlled trials (RCTs) have compared PAH-targeted therapies with placebo or conventional therapies. …”
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Concentrated growth factors promote epithelization in the mastoid obliteration after canal wall down mastoidectomy by Mengyi Liu, Lue Zhang, Quanming Zhang, Nan Zeng, Shuo Li, Shuyue Guo, Yaqin Zhao, Mingxing Tang, Qiong Yang

“…Conclusion: The application of CGF to surgical cavity obliteration following a CWD mastoidectomy significantly promotes epithelialization, thereby achieving satisfactory results. Randomized controlled trials with a larger number of patients enrolled were worth launching in the future to better substantiate the value of CGF in obliteration of mastoid cavity. …”
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Long-Term Results After Laparoscopic Lavage for Perforated Diverticulitis Purulent Peritonitis in Sweden: A Population-Based Observational Study by Andreas Samuelsson, MD, David Bock, PhD, Mattias Prytz, MD, PhD, Carolina Ehrencrona, BSc, Anette Wedin, RN, Eva Angenete, MD, PhD, Eva Haglind, MD, PhD

“…Laparoscopic lavage has been studied in 3 randomized controlled trials. Long-term results indicate that additional surgery and a remaining stoma are less common after lavage compared with resection, but data from routine care and larger cohorts are needed to get a more complete picture. …”
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The multiple uses of artificial intelligence in exercise programs: a narrative review by Alberto Canzone, Alberto Canzone, Giacomo Belmonte, Antonino Patti, Domenico Savio Salvatore Vicari, Domenico Savio Salvatore Vicari, Fabio Rapisarda, Valerio Giustino, Patrik Drid, Antonino Bianco

“…Machine learning, a subset of artificial intelligence, concentrates on empowering computers to learn and enhance from data autonomously; this narrative review seeks to elucidate the utilization of artificial intelligence in fostering physical activity, training, exercise, and health outcomes, addressing a significant gap in the comprehension of practical applications.MethodsOnly Randomized Controlled Trials (RCTs) published in English were included. …”
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Trends and Clinical Implications of Pediatric Pulmonary Function After Hematopoietic Stem Cell Transplantation: A Systematic Review by Xiaowei Zhao, Yuqi Zhao, Guoyu Ding, Xue Li, Xiaoyue Zhang, Yanli Leng, Hongmei Wang

“…The review included cohort studies, randomized controlled trials, and case‐control studies that assessed pulmonary function using standardized PFTs. …”
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Systematic review and meta-analysis of T1 glottic cancer outcomes comparing CO2 transoral laser microsurgery and radiotherapy by Michael F. Vaculik, Colin A. MacKay, S. Mark Taylor, Johnathan R. B. Trites, Robert D. Hart, Matthew H. Rigby

“…Limitations of our study include lack of randomized control trials, and non-randomized allocation of patients to treatment groups. …”
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Effects of Cinnamomum zeylanicum (Ceylon cinnamon) extract on lipid profile, glucose levels and its safety in adults: A randomized, double-blind, controlled trial. by Dimuthu Muthukuda, Chamini Kanatiwela de Silva, Saumiyah Ajanthan, Namal Wijesinghe, Anuradha Dahanayaka, Arunasalam Pathmeswaran

“…However, there are no well-conducted randomized controlled trials that can accurately measure the lipid and glucose-lowering effects of Cinnamomum zeylanicum (C. zeylanicum) extract. …”
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Near-infrared spectroscopy–guided personalized repetitive transcranial magnetic stimulation for bipolar depression: a case report by Chun-Hung Chang, Chun-Hung Chang, Chun-Hung Chang, Wen-Chun Liu, Po-Han Chou

“…Although our findings are promising, further randomized controlled trials are needed to validate the efficacy and safety of and determine the optimal parameters for this approach.…”
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Different Effects of Structured Education on Glycemic Control and Psychological Outcomes in Adolescent and Adult Patients with Type 1 Diabetes: A Systematic Review and Meta-Analysi... by Fang Liu, Yuzhu Guan, Xia Li, Yuting Xie, Jing He, Zhi-Guang Zhou, Lezhi Li

“…Electronic databases (EMBASE, Medline, PubMed, and the Cochrane Library) and the reference lists of included studies were searched from the beginning of the database through April 2019. Randomized controlled trials comparing SE with a control condition and reporting a change in glycosylated hemoglobin (HbA1c) level were included. …”
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Type of arrhythmias and the risk of sudden cardiac death in dialysis patients: a systematic review and meta-analysis by Subhash Chander, Ahmad Bin Aamir, Rabia Latif, Om Parkash, F. N. U. Sorath, Sam Tan, Abhi Chand Lohana, Sheena Shiwlani, Mohammed Yaqub Nadeem

“…Eight included studies were randomized controlled trials, and five were cohort studies, which provided a pooled population size of 12,611 dialysis patients for the meta-analysis, which indicated a significantly larger effect size of arrhythmia [Cohen’s d = 110.38 (95%CI 42.72–178.05), p = 0.0]. …”
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The effectiveness of dyadic interventions for health outcomes of prostate cancer patients and informal caregivers: a systematic review and meta-analysis by Yuan Xiao, Jiao Sun, Min Liu, Haifeng Wang, Jingjing Guan

“…However, given features such as research quality and sample size, further randomized controlled trials with excellent study designs are needed in the future to evaluate and validate the efficacy of dyadic care treatments for patients with prostate cancer. …”
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Effectiveness of a Dyadic Technology–Enhanced Home-Based Horticultural Therapy on Psychosocial Well-Being Among People With Dementia and Their Family Caregivers: Multimethods Pilot... by Patrick Pui Kin Kor, Justina Yat Wa Liu, Arkers Kwan Ching Wong, Alex Pak Lik Tsang, Han Zhi Tan, Daphne Sze Ki Cheung, Humphrey Kwong Wai Leung, Frances Kam Yuet Wong

“…Therefore, large-scale randomized controlled trials are encouraged to further confirm the effectiveness of the intervention. …”
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Shenkang injection for the treatment of acute kidney injury: a systematic review and meta-analysis by Shengchun Liao, Yurou Chen, Shuting Wang, Chen Wang, Chaoyang Ye

“…The objective of this systematic review was to assess the efficacy of Shenkang injection for the treatment of acute kidney injury (AKI).Methods A search was conducted across seven databases, encompassing data from the inception of each database through October 8th, 2023. Randomized controlled trials comparing SKI-treated AKI patients with control subjects were extracted. …”
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Exploring the association between statins use or HMG-CoA reductase inhibition and migraine: a systematic review and meta-analysis by Hamdy A. Makhlouf, Amr K. Hassan, Nereen A. Almosilhy, Ahmed S.A. Osman, Shrouk Ramadan, Moaz Elsayed Abouelmagd

“…Meta-analysis of randomized controlled trials (RCTs) showed that statins significantly reduced monthly migraine frequency (MD= -3.16, 95%CI= [-5.79, -0.53]; p = 0.02, I2 = 79%; P = 0.03). …”
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Sodium‐glucose cotransporter‐2 inhibitors in heart failure: an updated meta‐analysis by Yang Cao, Pengxiao Li, Yi Li, Yaling Han

“…Methods and results PubMed, Web of Science, and Cochrane Library were searched to identify randomized controlled trials comparing SGLT2i vs. placebo in HF patients. …”
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